PT2947086T - Novo composto de pirimidina fundida ou sal do mesmo - Google Patents
Novo composto de pirimidina fundida ou sal do mesmoInfo
- Publication number
- PT2947086T PT2947086T PT148367824T PT14836782T PT2947086T PT 2947086 T PT2947086 T PT 2947086T PT 148367824 T PT148367824 T PT 148367824T PT 14836782 T PT14836782 T PT 14836782T PT 2947086 T PT2947086 T PT 2947086T
- Authority
- PT
- Portugal
- Prior art keywords
- salt
- pyrimidine compound
- fused pyrimidine
- novel fused
- novel
- Prior art date
Links
- -1 pyrimidine compound Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013167600 | 2013-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2947086T true PT2947086T (pt) | 2018-03-09 |
Family
ID=52468312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT148367824T PT2947086T (pt) | 2013-08-12 | 2014-08-11 | Novo composto de pirimidina fundida ou sal do mesmo |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9580432B2 (enExample) |
| EP (1) | EP2947086B1 (enExample) |
| JP (1) | JP6035423B2 (enExample) |
| KR (1) | KR101828187B1 (enExample) |
| CN (1) | CN105452257B (enExample) |
| AU (1) | AU2014307437B2 (enExample) |
| BR (1) | BR112016002069B1 (enExample) |
| CA (1) | CA2921208C (enExample) |
| DK (1) | DK2947086T3 (enExample) |
| ES (1) | ES2661733T3 (enExample) |
| HU (1) | HUE036834T2 (enExample) |
| MX (1) | MX360498B (enExample) |
| MY (1) | MY171831A (enExample) |
| NO (1) | NO2947086T3 (enExample) |
| PH (1) | PH12015502737B1 (enExample) |
| PL (1) | PL2947086T3 (enExample) |
| PT (1) | PT2947086T (enExample) |
| RU (1) | RU2666349C2 (enExample) |
| SG (1) | SG11201600048VA (enExample) |
| TR (1) | TR201802875T4 (enExample) |
| TW (1) | TWI585089B (enExample) |
| WO (1) | WO2015022926A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014308616B2 (en) | 2013-08-23 | 2018-12-06 | Neupharma, Inc. | Certain chemical entities, compositions, and methods |
| HUE038041T2 (hu) | 2015-01-30 | 2018-10-29 | Taiho Pharmaceutical Co Ltd | Fuzionált pirimidin vegyület új sója és annak kristálya |
| MX381234B (es) * | 2015-01-30 | 2025-03-12 | Taiho Pharmaceutical Co Ltd | Agente preventivo y/o terapéutico de enfermedad inmune. |
| MY191938A (en) * | 2015-09-01 | 2022-07-19 | Taiho Pharmaceutical Co Ltd | Novel pyrazolo[3,4-d]pyrimidine compound or salt thereof |
| MA41559A (fr) * | 2015-09-08 | 2017-12-26 | Taiho Pharmaceutical Co Ltd | Composé de pyrimidine condensé ou un sel de celui-ci |
| TWI642671B (zh) * | 2015-10-28 | 2018-12-01 | 台灣神隆股份有限公司 | 依魯替尼之製備方法及其中間體 |
| PL3269370T3 (pl) | 2016-02-23 | 2020-06-01 | Taiho Pharmaceutical Co., Ltd. | Nowy skondensowany związek pirymidynowy lub jego sól |
| JP7101165B2 (ja) * | 2016-08-15 | 2022-07-14 | ニューファーマ， インコーポレイテッド | 特定の化学的実体、組成物、および方法 |
| TWI831739B (zh) * | 2017-02-28 | 2024-02-11 | 日商大鵬藥品工業股份有限公司 | 使用吡唑并[3,4-d]嘧啶化合物之抗腫瘤效果增強劑 |
| US12258376B2 (en) | 2017-08-21 | 2025-03-25 | Taiho Pharmaceutical Co., Ltd. | Fusion protein of DCTN1 protein with RET protein |
| MY206124A (en) * | 2019-01-11 | 2024-11-30 | Taiho Pharmaceutical Co Ltd | Pyrimidine compound or salt thereof |
| CN114364798A (zh) | 2019-03-21 | 2022-04-15 | 欧恩科斯欧公司 | 用于治疗癌症的Dbait分子与激酶抑制剂的组合 |
| US20220401436A1 (en) | 2019-11-08 | 2022-12-22 | INSERM (Institute National de la Santé et de la Recherche Médicale) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| EP4079306A4 (en) * | 2019-12-19 | 2024-01-10 | Taiho Pharmaceutical Co., Ltd. | THERAPEUTIC AGENT CONTAINING A PYRIMIDINE COMPOUND AS ACTIVE INGREDIENT |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| EP4183395A4 (en) * | 2020-07-15 | 2024-07-24 | Taiho Pharmaceutical Co., Ltd. | PYRIMIDINE COMPOUND-CONTAINING COMBINATION FOR USE IN TUMOR TREATMENT |
| WO2022140246A1 (en) | 2020-12-21 | 2022-06-30 | Hangzhou Jijing Pharmaceutical Technology Limited | Methods and compounds for targeted autophagy |
| CN114736207B (zh) * | 2022-04-28 | 2023-03-31 | 武汉九州钰民医药科技有限公司 | 一种小分子her2抑制剂的制备工艺 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005042556A1 (en) | 2003-10-27 | 2005-05-12 | Genelabs Technologies, Inc. | Nucleoside compounds for treating viral infections |
| WO2007067781A2 (en) | 2005-12-08 | 2007-06-14 | Abbott Laboratories | 9-membered heterobicyclic compounds as inhibitors of protein kinases |
| WO2007126841A2 (en) | 2006-03-29 | 2007-11-08 | Foldrx Pharmaceuticals, Inc. | Inhibition of alpha-synuclein toxicity |
| EP2089391B1 (en) | 2006-11-03 | 2013-01-16 | Pharmacyclics, Inc. | Bruton's tyrosine kinase activity probe and method of using |
| ES2562215T3 (es) | 2007-03-28 | 2016-03-03 | Pharmacyclics Llc | Inhibidores de la tirosina quinasa de Bruton |
| JP2009235057A (ja) | 2007-10-31 | 2009-10-15 | Santen Pharmaceut Co Ltd | 血管新生阻害活性を有する新規インドール誘導体 |
| US8338439B2 (en) | 2008-06-27 | 2012-12-25 | Celgene Avilomics Research, Inc. | 2,4-disubstituted pyrimidines useful as kinase inhibitors |
| CA2986640C (en) | 2008-06-27 | 2019-03-26 | Celgene Avilomics Research, Inc. | Heteroaryl compounds and uses thereof |
| CN103857396A (zh) | 2011-07-13 | 2014-06-11 | 药品循环公司 | 布鲁顿酪氨酸激酶抑制剂 |
| CN103717247B (zh) * | 2011-07-15 | 2016-04-27 | 赛诺菲-安万特德国有限公司 | 药物输送装置 |
| PT2657233E (pt) | 2012-01-19 | 2014-10-24 | Taiho Pharmaceutical Co Ltd | Composto de alcinil-benzeno substituído nas posições 3 e 5 e um seu sal |
| CN104250250A (zh) * | 2013-06-25 | 2014-12-31 | 苏州科捷生物医药有限公司 | 4-芳香胺基嘧啶类化合物及其抗肿瘤用途 |
-
2014
- 2014-08-11 BR BR112016002069-3A patent/BR112016002069B1/pt active IP Right Grant
- 2014-08-11 TR TR2018/02875T patent/TR201802875T4/tr unknown
- 2014-08-11 MY MYPI2015704772A patent/MY171831A/en unknown
- 2014-08-11 CA CA2921208A patent/CA2921208C/en active Active
- 2014-08-11 CN CN201480043405.1A patent/CN105452257B/zh active Active
- 2014-08-11 WO PCT/JP2014/071158 patent/WO2015022926A1/ja not_active Ceased
- 2014-08-11 AU AU2014307437A patent/AU2014307437B2/en active Active
- 2014-08-11 TW TW103127536A patent/TWI585089B/zh active
- 2014-08-11 KR KR1020167003396A patent/KR101828187B1/ko active Active
- 2014-08-11 DK DK14836782.4T patent/DK2947086T3/en active
- 2014-08-11 NO NO14836782A patent/NO2947086T3/no unknown
- 2014-08-11 MX MX2016001845A patent/MX360498B/es active IP Right Grant
- 2014-08-11 HU HUE14836782A patent/HUE036834T2/hu unknown
- 2014-08-11 US US14/784,239 patent/US9580432B2/en active Active
- 2014-08-11 RU RU2015156524A patent/RU2666349C2/ru active
- 2014-08-11 PT PT148367824T patent/PT2947086T/pt unknown
- 2014-08-11 EP EP14836782.4A patent/EP2947086B1/en active Active
- 2014-08-11 PL PL14836782T patent/PL2947086T3/pl unknown
- 2014-08-11 ES ES14836782.4T patent/ES2661733T3/es active Active
- 2014-08-11 SG SG11201600048VA patent/SG11201600048VA/en unknown
- 2014-08-11 JP JP2015531804A patent/JP6035423B2/ja active Active
-
2015
- 2015-12-07 PH PH12015502737A patent/PH12015502737B1/en unknown
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