PT2942082T - Antagonistas do recetor de a2a para utilização no tratamento de distúrbios de movimento - Google Patents

Antagonistas do recetor de a2a para utilização no tratamento de distúrbios de movimento

Info

Publication number
PT2942082T
PT2942082T PT15165962T PT15165962T PT2942082T PT 2942082 T PT2942082 T PT 2942082T PT 15165962 T PT15165962 T PT 15165962T PT 15165962 T PT15165962 T PT 15165962T PT 2942082 T PT2942082 T PT 2942082T
Authority
PT
Portugal
Prior art keywords
treatment
movement disorders
receptor antogonists
antogonists
receptor
Prior art date
Application number
PT15165962T
Other languages
English (en)
Inventor
Kase Hiroshi
Karasawa Akira
Mori Akihisa
Waki Yutaka
Ohsawa Yutaka
Kuwana Yoshihisa
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27663091&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2942082(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of PT2942082T publication Critical patent/PT2942082T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT15165962T 2002-01-28 2003-01-28 Antagonistas do recetor de a2a para utilização no tratamento de distúrbios de movimento PT2942082T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35241302P 2002-01-28 2002-01-28

Publications (1)

Publication Number Publication Date
PT2942082T true PT2942082T (pt) 2019-06-06

Family

ID=27663091

Family Applications (2)

Application Number Title Priority Date Filing Date
PT10179406T PT2260850T (pt) 2002-01-28 2003-01-28 Antagonistas do recetor de a2a para utilização no tratamento de distúrbios de movimento
PT15165962T PT2942082T (pt) 2002-01-28 2003-01-28 Antagonistas do recetor de a2a para utilização no tratamento de distúrbios de movimento

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT10179406T PT2260850T (pt) 2002-01-28 2003-01-28 Antagonistas do recetor de a2a para utilização no tratamento de distúrbios de movimento

Country Status (16)

Country Link
US (7) US20040198753A1 (pt)
EP (4) EP2942082B1 (pt)
JP (3) JP4376630B2 (pt)
KR (5) KR101098209B1 (pt)
CN (3) CN1646132A (pt)
AU (2) AU2003207734C1 (pt)
BR (1) BR0306919A (pt)
CA (2) CA2473864C (pt)
CO (1) CO5601022A2 (pt)
EA (1) EA200400982A1 (pt)
ES (2) ES2686123T3 (pt)
HU (2) HUE039348T2 (pt)
MX (1) MXPA04007299A (pt)
PT (2) PT2260850T (pt)
TR (1) TR201903603T4 (pt)
WO (1) WO2003063876A2 (pt)

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GB2348371B (en) * 2000-03-14 2001-04-04 Soares Da Silva Patricio Compositions comprising blockers of L-DOPA renal cell transfer for the treatment of Parkinson's disease
EP2942082B1 (en) * 2002-01-28 2019-03-06 Kyowa Hakko Kogyo Co., Ltd A2a receptor antogonists for use in the treatment of movement disorders
AU2003262860A1 (en) * 2002-08-30 2004-03-19 Kyowa Hakko Kogyo Co., Ltd. Adenosine a2a receptor antagonists for treating restless legs syndrome or related disorders
US20060128694A1 (en) * 2002-12-19 2006-06-15 Michael Grzelak Adenosine A2a receptor antagonists for the treatment of extra-pyramidal syndrome and other movement disorders
AU2003304527B2 (en) * 2002-12-19 2010-09-09 Merck Sharp & Dohme Corp. Uses of adenosine A2a receptor antagonists
US20060106040A1 (en) * 2002-12-19 2006-05-18 Michael Grzelak Adenosine A2a receptor antagonists for the treatment of extra-pyramidal syndrome and other movement disorders
AR056615A1 (es) * 2002-12-27 2007-10-17 Kyowa Hakko Kogyo Kk Un metodo de tratamiento de trastornos de la conducta
TW200507850A (en) 2003-07-25 2005-03-01 Kyowa Hakko Kogyo Kk Pharmaceutical composition
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US20050197385A1 (en) * 2004-02-20 2005-09-08 Schwarz Pharma Ag Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
EP1824495A2 (en) * 2004-12-03 2007-08-29 ProteoSys AG Finasteride, dutasteride and related compounds for preventing/treating neurologically-associated disorders
MY140748A (en) 2004-12-06 2010-01-15 Astrazeneca Ab Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
ATE556712T1 (de) * 2005-06-07 2012-05-15 Kyowa Hakko Kirin Co Ltd A2a antagonisten zur behandlung von motorischen störungen
US9066903B2 (en) * 2006-02-28 2015-06-30 The United States Of America As Represented By The Department Of Veterans Affairs Pharmacological treatment of Parkinson's disease
US8802002B2 (en) 2006-12-28 2014-08-12 3M Innovative Properties Company Dimensionally stable bonded nonwoven fibrous webs
US20090054468A1 (en) * 2007-08-23 2009-02-26 Astrazeneca Ab New Use 938
US20090118376A1 (en) * 2007-11-02 2009-05-07 Ru-Band Lu Memantine Protects Inflammation-Related Degeneration of Dopamine Neurons Through Inhibition of Over-Activated Microglia and Release of Neurotrophic Factors from Astroglia
KR101742668B1 (ko) 2008-06-12 2017-06-01 골지 피티와이 리미티드 운동부족 및/또는 운동과잉 상태의 검출
CA2750265A1 (en) * 2009-01-20 2010-07-29 Marc Cantillon Methods of alleviating or treating signs and/or symptoms associated with moderate to severe parkinson's disease
TWI548411B (zh) 2009-04-28 2016-09-11 Kyowa Hakko Kirin Co Ltd Exercise disorder treatment
WO2012060844A1 (en) * 2010-11-05 2012-05-10 Biotie Therapies, Inc A2a antagonists as cognition and motor function enhancers
US10258632B2 (en) * 2012-06-05 2019-04-16 International Stem Cell Corporation Method of prevention of neurological diseases
US9012640B2 (en) * 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives
CA2902756A1 (en) 2013-03-01 2014-09-04 Global Kinetics Corporation Pty Ltd System and method for assessing impulse control disorder
US10040817B2 (en) 2013-10-03 2018-08-07 Enterin Laboratories, Inc. Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
JP6381883B2 (ja) * 2013-10-04 2018-08-29 国立大学法人千葉大学 不随意運動の予防及び／又は治療組成物
US10736577B2 (en) 2014-03-03 2020-08-11 Global Kinetics Pty Ltd Method and system for assessing motion symptoms
WO2016148260A1 (ja) * 2015-03-17 2016-09-22 協和発酵キリン株式会社 医薬組成物
CA2988918A1 (en) 2015-06-19 2016-12-22 Biotie Therapies, Inc. Controlled-release tozadenant formulations
JP2019510088A (ja) * 2016-03-17 2019-04-11 ザ ジョンズ ホプキンス ユニバーシティーＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ Ｐａｒｉｓのファルネシル化によってパーキンソン病を予防または治療する方法
US10973815B2 (en) 2016-03-31 2021-04-13 Versi Group, Llc Delta opioid agonist mu opioid antagonist compositions and methods for treating Parkinsons disease
US11246871B2 (en) 2016-07-15 2022-02-15 Northwestern University Targeting adenosine A2A receptors for the treatment of levodopa-induced dyskinesias
WO2020189781A1 (ja) 2019-03-21 2020-09-24 協和キリン株式会社 パーキンソン病治療剤
EP3714888A1 (en) * 2019-03-25 2020-09-30 Assistance Publique - Hôpitaux De Paris Compounds for use in the treatment of adcy5-related dyskinesia
JP7382737B2 (ja) * 2019-05-13 2023-11-17 東和薬品株式会社 イストラデフィリン製剤
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EP2942082B1 (en) * 2002-01-28 2019-03-06 Kyowa Hakko Kogyo Co., Ltd A2a receptor antogonists for use in the treatment of movement disorders
AU2003262860A1 (en) * 2002-08-30 2004-03-19 Kyowa Hakko Kogyo Co., Ltd. Adenosine a2a receptor antagonists for treating restless legs syndrome or related disorders
DE602004029160D1 (pt) * 2003-06-10 2010-10-28 Kyowa Hakko Kirin Co Ltd
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US9238003B2 (en) * 2005-02-04 2016-01-19 Auburn University Extended or continuous wear silicone hydrogel contact lenses for the extended release of comfort molecules

Also Published As

Publication number Publication date
KR20110010829A (ko) 2011-02-07
CN101822676A (zh) 2010-09-08
KR101098209B1 (ko) 2011-12-23
WO2003063876A3 (en) 2003-11-27
EP1469855A2 (en) 2004-10-27
US20120122897A1 (en) 2012-05-17
JP2012140461A (ja) 2012-07-26
WO2003063876A2 (en) 2003-08-07
EP2260850A2 (en) 2010-12-15
MXPA04007299A (es) 2004-10-29
CA2473864A1 (en) 2003-08-07
EP2260850A3 (en) 2013-11-13
US20060148827A1 (en) 2006-07-06
BR0306919A (pt) 2004-11-09
PT2260850T (pt) 2018-10-24
US20170196872A1 (en) 2017-07-13
CA2473864C (en) 2013-06-11
TR201903603T4 (tr) 2019-04-22
US20040198753A1 (en) 2004-10-07
EP2044940A3 (en) 2010-11-10
HUE043353T2 (hu) 2019-08-28
KR101166000B1 (ko) 2012-07-16
CN101543497A (zh) 2009-09-30
CO5601022A2 (es) 2006-01-31
EA200400982A1 (ru) 2004-12-30
AU2003207734B2 (en) 2008-02-21
EP2942082A3 (en) 2016-01-27
ES2686123T3 (es) 2018-10-16
ES2716404T3 (es) 2019-06-12
AU2003207734C1 (en) 2009-10-08
AU2008200611B2 (en) 2011-12-15
JP2009067807A (ja) 2009-04-02
US7727993B2 (en) 2010-06-01
EP2044940A2 (en) 2009-04-08
CA2813048A1 (en) 2003-08-07
US20140249166A1 (en) 2014-09-04
KR20100056569A (ko) 2010-05-27
US20180221377A1 (en) 2018-08-09
EP2942082B1 (en) 2019-03-06
JP5171556B2 (ja) 2013-03-27
JP5612016B2 (ja) 2014-10-22
HUE039348T2 (hu) 2018-12-28
KR20040077763A (ko) 2004-09-06
CN1646132A (zh) 2005-07-27
JP2005523898A (ja) 2005-08-11
JP4376630B2 (ja) 2009-12-02
US20060178379A1 (en) 2006-08-10
KR20150080013A (ko) 2015-07-08
EP2942082A2 (en) 2015-11-11
EP2260850B1 (en) 2018-07-04
US7727994B2 (en) 2010-06-01
AU2008200611A1 (en) 2008-03-06
KR20120103740A (ko) 2012-09-19

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