PT2776382T - Folatos de 18f-sacárido - Google Patents

Folatos de 18f-sacárido

Info

Publication number
PT2776382T
PT2776382T PT12748492T PT12748492T PT2776382T PT 2776382 T PT2776382 T PT 2776382T PT 12748492 T PT12748492 T PT 12748492T PT 12748492 T PT12748492 T PT 12748492T PT 2776382 T PT2776382 T PT 2776382T
Authority
PT
Portugal
Prior art keywords
folates
saccharide
Prior art date
Application number
PT12748492T
Other languages
English (en)
Inventor
Moser Rudolf
Mensah Ametamey Simon
Groehn Viola
Schibli Roger
Magdalena Müller Cristina
Ramona Fischer Cindy
Original Assignee
Merck & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Cie filed Critical Merck & Cie
Publication of PT2776382T publication Critical patent/PT2776382T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/005Sugars; Derivatives thereof; Nucleosides; Nucleotides; Nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nuclear Medicine (AREA)
PT12748492T 2011-08-22 2012-08-21 Folatos de 18f-sacárido PT2776382T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11178260 2011-08-22

Publications (1)

Publication Number Publication Date
PT2776382T true PT2776382T (pt) 2018-12-24

Family

ID=46704677

Family Applications (1)

Application Number Title Priority Date Filing Date
PT12748492T PT2776382T (pt) 2011-08-22 2012-08-21 Folatos de 18f-sacárido

Country Status (18)

Country Link
US (2) US10322195B2 (pt)
EP (1) EP2776382B1 (pt)
JP (1) JP6161209B2 (pt)
KR (1) KR101994327B1 (pt)
CN (1) CN103732563B (pt)
AU (2) AU2012298546A1 (pt)
CA (1) CA2839654C (pt)
DK (1) DK2776382T3 (pt)
EA (1) EA201400253A1 (pt)
ES (1) ES2703107T3 (pt)
HK (1) HK1194355A1 (pt)
IL (1) IL230760A (pt)
PL (1) PL2776382T3 (pt)
PT (1) PT2776382T (pt)
SG (2) SG2014001085A (pt)
TR (1) TR201819447T4 (pt)
WO (1) WO2013026842A1 (pt)
ZA (1) ZA201400175B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10029995B2 (en) 2015-09-03 2018-07-24 Forma Therapeutics, Inc. [6,6] fused bicyclic HDAC8 inhibitors
TWI732825B (zh) * 2016-05-20 2021-07-11 日商王子控股股份有限公司 圖案形成用定向自組裝組成物、圖案形成用定向自組裝組成物用單體及圖案形成方法
CN109232690A (zh) * 2018-09-10 2019-01-18 南方医科大学南方医院 一种正电子显像剂标准品前体及其制备方法
EP3671511B1 (en) 2018-12-19 2022-07-06 Rohde & Schwarz GmbH & Co. KG Communication system and method
CN111714640B (zh) * 2019-03-14 2023-02-14 北京和益源生物技术有限公司 一种糖修饰的叶酸衍生物制备的纳米运载颗粒及其应用
CN111748002B (zh) * 2019-03-14 2022-03-29 北京和益源生物技术有限公司 一种脱氧葡萄糖修饰的叶酸衍生物及其合成与应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276280A (en) 1976-09-29 1981-06-30 Becton, Dickinson And Company Radiolabeled derivatives of folic acid
US4628090A (en) 1984-08-21 1986-12-09 Rensselaer Polytechnic Institute Fluorine-containing antifolates incapable of polyglutanayte formation related compounds
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
ES2566761T3 (es) 2002-05-30 2016-04-15 The Scripps Research Institute Ligación de azidas y acetilenos catalizada por cobre
EP2452695A3 (en) 2004-12-23 2013-01-23 Purdue Research Foundation Positron emission tomography imaging method
EP1875240A2 (en) 2005-04-27 2008-01-09 Siemens Medical Solutions USA, Inc. The preparation of molecular imaging probes using click chemistry
WO2007042504A2 (fr) * 2005-10-07 2007-04-19 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
EP2109466B1 (en) 2007-02-07 2014-11-12 Purdue Research Foundation Positron emission tomography imaging method
CA2670379C (en) * 2007-04-11 2015-06-23 Merck Eprova Ag 18f-labelled folates
PL2146944T3 (pl) 2007-04-11 2014-05-30 Merck & Cie Sposób otrzymywania folianów znakowanych fluorem-18
KR101639268B1 (ko) * 2007-04-11 2016-07-13 메르크 앤드 씨에 18 f-표지된 폴레이트
EP2194068B1 (en) * 2007-09-28 2013-04-17 Nanodex INC. Cyclodextrin compound modified with folic acid, process for production thereof, drug delivery agent for targeting drug delivery system, pharmaceutical composition, and imaging agent
SG195545A1 (en) * 2008-10-10 2013-12-30 Merck & Cie 18f-labelled folates as pet radiotracers
WO2013024035A1 (en) * 2011-08-17 2013-02-21 Merck & Cie Folate conjugates of albumin-binding entities

Also Published As

Publication number Publication date
CN103732563A (zh) 2014-04-16
PL2776382T3 (pl) 2019-05-31
SG10201606981QA (en) 2016-10-28
DK2776382T3 (en) 2019-01-14
SG2014001085A (en) 2014-03-28
HK1194355A1 (zh) 2014-10-17
CN103732563B (zh) 2016-04-20
EP2776382B1 (en) 2018-09-19
CA2839654C (en) 2021-02-16
US10973936B2 (en) 2021-04-13
EP2776382A1 (en) 2014-09-17
IL230760A0 (en) 2014-03-31
CA2839654A1 (en) 2013-02-28
AU2017203512A1 (en) 2017-06-15
US20140193337A1 (en) 2014-07-10
TR201819447T4 (tr) 2019-01-21
IL230760A (en) 2017-08-31
JP2014531411A (ja) 2014-11-27
KR101994327B1 (ko) 2019-06-28
US10322195B2 (en) 2019-06-18
AU2012298546A1 (en) 2014-02-20
JP6161209B2 (ja) 2017-07-12
WO2013026842A1 (en) 2013-02-28
ZA201400175B (en) 2015-08-26
ES2703107T3 (es) 2019-03-07
US20190255200A1 (en) 2019-08-22
AU2017203512B2 (en) 2019-02-28
EA201400253A1 (ru) 2014-08-29
KR20140054284A (ko) 2014-05-08

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