PT2683824T - Modificação de microorganismos thraustochytrid - Google Patents
Modificação de microorganismos thraustochytridInfo
- Publication number
- PT2683824T PT2683824T PT127550515T PT12755051T PT2683824T PT 2683824 T PT2683824 T PT 2683824T PT 127550515 T PT127550515 T PT 127550515T PT 12755051 T PT12755051 T PT 12755051T PT 2683824 T PT2683824 T PT 2683824T
- Authority
- PT
- Portugal
- Prior art keywords
- engineering
- thraustochytrid microorganisms
- thraustochytrid
- microorganisms
- engineering thraustochytrid
- Prior art date
Links
- 241001467333 Thraustochytriaceae Species 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8206—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated
- C12N15/8207—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated by mechanical means, e.g. microinjection, particle bombardment, silicon whiskers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449848P | 2011-03-07 | 2011-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2683824T true PT2683824T (pt) | 2018-06-07 |
Family
ID=46797543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT127550515T PT2683824T (pt) | 2011-03-07 | 2012-03-07 | Modificação de microorganismos thraustochytrid |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9133463B2 (pt) |
| EP (1) | EP2683824B1 (pt) |
| JP (1) | JP6168700B2 (pt) |
| CN (2) | CN107630017A (pt) |
| AU (1) | AU2012226528B2 (pt) |
| CA (1) | CA2829296C (pt) |
| DK (1) | DK2683824T3 (pt) |
| ES (1) | ES2678997T3 (pt) |
| MX (1) | MX338479B (pt) |
| NO (1) | NO2773848T3 (pt) |
| PT (1) | PT2683824T (pt) |
| WO (1) | WO2012120375A1 (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101180462B1 (ko) | 2000-01-19 | 2012-09-06 | 마텍 바이오싸이언스스 코포레이션 | 무용매 추출 방법 |
| ES2758782T3 (es) | 2010-06-01 | 2020-05-06 | Dsm Ip Assets Bv | Extracción de lípido de células y productos del mismo |
| WO2012120375A1 (en) * | 2011-03-07 | 2012-09-13 | Ocean Nutrition Canada Limited | Engineering thraustochytrid microorganisms |
| US9873880B2 (en) | 2013-03-13 | 2018-01-23 | Dsm Nutritional Products Ag | Engineering microorganisms |
| CN115141859A (zh) | 2013-12-20 | 2022-10-04 | 玛拉可再生能源公司 | 从微生物中回收油的方法 |
| BR112016014208B1 (pt) | 2013-12-20 | 2022-09-20 | Dsm Nutricional Products Ag | Método de extração de lipídeos a partir de uma população de micro-organismos |
| TWI646188B (zh) | 2013-12-20 | 2019-01-01 | 荷蘭商Ｄｓｍ智慧財產有限公司 | 用於從微生物細胞獲得微生物油之方法（四） |
| NZ721413A (en) | 2013-12-20 | 2022-05-27 | Dsm Ip Assets Bv | Processes for obtaining microbial oil from microbial cells |
| KR102552228B1 (ko) | 2013-12-20 | 2023-07-05 | 디에스엠 아이피 어셋츠 비.브이. | 미생물 세포로부터의 미생물 오일의 수득 방법 |
| ES2796079T3 (es) | 2013-12-20 | 2020-11-25 | Dsm Ip Assets Bv | Procesos para obtener aceite microbiano de células microbianas |
| KR102236782B1 (ko) | 2014-05-22 | 2021-04-05 | 마라 리뉴어블즈 코퍼레이션 | 미생물에서 오일 생산 방법 |
| CN106604998B (zh) | 2014-10-16 | 2021-03-30 | 玛拉可再生能源公司 | 重复补料分批培养方法 |
| ES2856838T3 (es) * | 2014-10-16 | 2021-09-28 | Mara Renewables Corp | Métodos de cultivo semicontinuo |
| EP3098318A1 (en) * | 2015-01-24 | 2016-11-30 | Indian Oil Corporation Limited | Thraustochytrid based process for treating waste effluents |
| EP3265567B1 (en) | 2015-03-02 | 2020-07-29 | Conagen Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
| US20160264985A1 (en) * | 2015-03-12 | 2016-09-15 | Synthetic Genomics, Inc. | Microorganisms for fatty acid production using elongase and desaturase enzymes |
| AR104042A1 (es) | 2015-03-26 | 2017-06-21 | Mara Renewables Corp | Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto |
| US20180320208A1 (en) * | 2015-07-03 | 2018-11-08 | Kyushu University, National University Corporation | Labyrinthulid microorganism capable of producing microbial oil, microbial oil, methods for producing said microorganism and for producing said microbial oil, and uses of said microorganism and said microbial oil |
| WO2017009790A1 (en) | 2015-07-13 | 2017-01-19 | MARA Renewables Corporation | Enhancing microalgal metabolism of xylose |
| FR3038914B1 (fr) * | 2015-07-17 | 2020-03-13 | Fermentalg | Biomasse de thraustochytrides, procede de culture et utilisations |
| CN106916796B (zh) * | 2015-12-28 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌delta-12脂肪酸脱饱和酶相关序列及其应用 |
| EP3430035A4 (en) * | 2016-03-16 | 2020-02-19 | Conagen Inc. | PRODUCTION OF PROTEINS IN LABYRINE THULOMYCETES |
| US10851395B2 (en) | 2016-06-10 | 2020-12-01 | MARA Renewables Corporation | Method of making lipids with improved cold flow properties |
| CN109415655A (zh) | 2016-07-20 | 2019-03-01 | 玛拉可再生能源公司 | 可流动的粗制微生物油以及生产方法 |
| EP3487969B1 (en) | 2016-07-20 | 2024-04-17 | Mara Renewables Corporation | A two-step fractionation method for winterizing oil. |
| US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
| MX2019007315A (es) * | 2016-12-22 | 2019-09-06 | Mara Renewables Corp | Metodos para producir biomasa rica en dha, acido palmitico y proteinas con un microorganismo eucariota. |
| CN109517834B (zh) * | 2018-11-27 | 2022-06-07 | 昆明藻能生物科技有限公司 | 一种通过遗传改造提高裂殖壶藻atcc20888油脂和dha含量的方法 |
| WO2023144707A1 (en) | 2022-01-25 | 2023-08-03 | Dsm Ip Assets B.V. | Media refinement and nutrient feeding approaches to increase polyunsaturated fatty acid production |
| WO2024006765A2 (en) * | 2022-06-27 | 2024-01-04 | Wisconsin Alumni Research Foundation | Universal method for parasite and eukaryotic endosymbiont identification |
| CN117721111B (zh) * | 2023-12-19 | 2024-06-07 | 海南省海洋与渔业科学院 | 红树植物白骨壤内源启动子amgt1p5及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
| US6451567B1 (en) | 1988-09-07 | 2002-09-17 | Omegatech, Inc. | Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms |
| US6027900A (en) * | 1996-04-12 | 2000-02-22 | Carnegie Institution Of Washington | Methods and tools for transformation of eukaryotic algae |
| US5968809A (en) | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| NZ520420A (en) | 2000-01-28 | 2005-03-24 | Martek Biosciences Corp | Enhanced production of lipids containing polyenoic fatty acids by high density cultures of eukaryotic microbes in fermentors |
| TWI350854B (en) | 2001-04-16 | 2011-10-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7211656B2 (en) | 2002-01-30 | 2007-05-01 | Abbott Laboratories | Desaturase genes, enzymes encoded thereby, and uses thereof |
| JP4280158B2 (ja) | 2002-12-27 | 2009-06-17 | 富士フイルム株式会社 | ドコサヘキサエン酸生産能を有する微生物及びその利用 |
| US7214491B2 (en) | 2003-05-07 | 2007-05-08 | E. I. Du Pont De Nemours And Company | Δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts |
| DE10352837A1 (de) * | 2003-11-10 | 2005-07-07 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Prozess zur Kultivierung von Mikroorganismen der Gattung Thraustochytriales |
| DE102004063326A1 (de) | 2004-12-23 | 2006-07-06 | Basf Plant Science Gmbh | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen |
| JP4796787B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
| JP4796786B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
| ES2451667T3 (es) * | 2005-06-07 | 2014-03-28 | Ocean Nutrition Canada Limited | Microorganismos eucariotas para producir lípidos y antioxidantes |
| CN101573451B (zh) * | 2006-03-15 | 2014-04-30 | Dsmip资产公司 | 利用pufa聚酮化合物合成酶系统在异源的生物体中产生多不饱和脂肪酸的方法 |
| EP2082053B1 (en) | 2006-08-01 | 2016-04-13 | DSM Nutritional Products AG | Process for producing microbial oil comprising polyunsaturated fatty acids |
| US8765422B2 (en) * | 2007-07-13 | 2014-07-01 | Dsm Nutritional Products Ag | D4 desaturases and D5 elongases |
| US8940884B2 (en) * | 2009-03-19 | 2015-01-27 | Dsm Ip Assets B.V. | Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof |
| KR20130026411A (en) * | 2009-09-24 | 2013-03-13 | Univ Kyushu Nat Univ Corp | Method for transforming stramenopile |
| KR101068520B1 (ko) * | 2009-10-07 | 2011-09-28 | 대상 주식회사 | 고함량의 도코사헥사엔산을 함유하는 오메가-3 불포화 지방산을 생산하는 균주 및 이를 이용한 오메가-3 불포화 지방산의 제조방법 |
| CA3153553A1 (en) | 2009-12-28 | 2011-07-28 | Sanofi Vaccine Technologies, S.A.S. | Methods of producing heterologous proteins comprising membrane domains in microalgal extracellular bodies |
| CA2791695C (en) | 2010-03-02 | 2018-04-24 | Massachusetts Institute Of Technology | Microbial engineering for the production of fatty acids and fatty acid derivatives |
| WO2012120375A1 (en) * | 2011-03-07 | 2012-09-13 | Ocean Nutrition Canada Limited | Engineering thraustochytrid microorganisms |
| US9873880B2 (en) * | 2013-03-13 | 2018-01-23 | Dsm Nutritional Products Ag | Engineering microorganisms |
-
2012
- 2012-03-07 WO PCT/IB2012/000528 patent/WO2012120375A1/en active Application Filing
- 2012-03-07 CA CA2829296A patent/CA2829296C/en not_active Expired - Fee Related
- 2012-03-07 MX MX2013010167A patent/MX338479B/es active IP Right Grant
- 2012-03-07 PT PT127550515T patent/PT2683824T/pt unknown
- 2012-03-07 EP EP12755051.5A patent/EP2683824B1/en not_active Not-in-force
- 2012-03-07 JP JP2013557186A patent/JP6168700B2/ja active Active
- 2012-03-07 CN CN201710887601.2A patent/CN107630017A/zh active Pending
- 2012-03-07 US US13/414,353 patent/US9133463B2/en active Active
- 2012-03-07 DK DK12755051.5T patent/DK2683824T3/en active
- 2012-03-07 ES ES12755051.5T patent/ES2678997T3/es active Active
- 2012-03-07 CN CN201280018055.4A patent/CN103649313B/zh not_active Expired - Fee Related
- 2012-03-07 AU AU2012226528A patent/AU2012226528B2/en not_active Ceased
- 2012-10-26 NO NO12845260A patent/NO2773848T3/no unknown
-
2015
- 2015-08-04 US US14/817,705 patent/US9758787B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9133463B2 (en) | 2015-09-15 |
| MX338479B (es) | 2016-04-19 |
| EP2683824B1 (en) | 2018-04-25 |
| CA2829296C (en) | 2019-10-29 |
| AU2012226528A1 (en) | 2013-05-02 |
| US9758787B2 (en) | 2017-09-12 |
| JP6168700B2 (ja) | 2017-07-26 |
| EP2683824A1 (en) | 2014-01-15 |
| MX2013010167A (es) | 2014-04-14 |
| NO2773848T3 (pt) | 2018-03-31 |
| CN103649313B (zh) | 2017-10-24 |
| WO2012120375A1 (en) | 2012-09-13 |
| CN107630017A (zh) | 2018-01-26 |
| JP2014507952A (ja) | 2014-04-03 |
| CA2829296A1 (en) | 2012-09-13 |
| US20160010095A1 (en) | 2016-01-14 |
| DK2683824T3 (en) | 2018-06-18 |
| ES2678997T3 (es) | 2018-08-21 |
| CN103649313A (zh) | 2014-03-19 |
| EP2683824A4 (en) | 2015-05-06 |
| US20120244584A1 (en) | 2012-09-27 |
| AU2012226528B2 (en) | 2015-08-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT2683824T (pt) | Modificação de microorganismos thraustochytrid | |
| IL228862A (en) | Imidazole derivatives are merged for use as ido engines | |
| ZA201404078B (en) | Bradyrhizobium strains | |
| HUE046097T2 (hu) | Átvezetés | |
| GB2501442B (en) | Dynamic binary optimization | |
| EP2752601A4 (en) | INTEGRATED SEAL INTO A PLATE | |
| EP2729605A4 (en) | RNA YY1 INTERACTIONS | |
| GB201112231D0 (en) | Micro-organism | |
| EP2754926A4 (en) | SEAL | |
| SG11201403280PA (en) | Bioreactor | |
| EP2746382A4 (en) | WHEAT BIOREACTOR | |
| EP2663331A4 (en) | NEW USES | |
| GB201105796D0 (en) | Seals | |
| EP2705458A4 (en) | ENGINEERING IDENTIFICATION TECHNOLOGIES | |
| SG11201503233UA (en) | Bacterial engineering | |
| PL2683966T3 (pl) | Uszczelka pół falista | |
| EP2736056A4 (en) | REACTOR | |
| GB2500854B (en) | Biosurface engineering | |
| GB201112812D0 (en) | Preventing anaerobic corrosion | |
| GB2491820B (en) | Clipboard | |
| GB201109862D0 (en) | Hydro clear | |
| GB201109024D0 (en) | Can | |
| GB201121295D0 (en) | Microorganisms | |
| GB201109627D0 (en) | Easy clear | |
| GB201110577D0 (en) | Culturing microorganisms |