PT2643342T - Novos agonistas do recetor de angiotensina tipo 2 (at2) e sua utilização - Google Patents

Novos agonistas do recetor de angiotensina tipo 2 (at2) e sua utilização

Info

Publication number
PT2643342T
PT2643342T PT117916361T PT11791636T PT2643342T PT 2643342 T PT2643342 T PT 2643342T PT 117916361 T PT117916361 T PT 117916361T PT 11791636 T PT11791636 T PT 11791636T PT 2643342 T PT2643342 T PT 2643342T
Authority
PT
Portugal
Prior art keywords
receptor agonists
angiotensin type
novel angiotensin
novel
type
Prior art date
Application number
PT117916361T
Other languages
English (en)
Inventor
De Vries Louwe
Adriaan Nelemans Sieger
Rink Rick
Jacobus Marinus Roks Antonius
Nikolaas Moll Gert
Original Assignee
Lanthiopep Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lanthiopep Bv filed Critical Lanthiopep Bv
Publication of PT2643342T publication Critical patent/PT2643342T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
PT117916361T 2010-11-23 2011-11-22 Novos agonistas do recetor de angiotensina tipo 2 (at2) e sua utilização PT2643342T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10192208A EP2455388A1 (en) 2010-11-23 2010-11-23 Novel angiotensin type 2 (AT2) receptor agonists and uses thereof.

Publications (1)

Publication Number Publication Date
PT2643342T true PT2643342T (pt) 2017-07-12

Family

ID=44072497

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117916361T PT2643342T (pt) 2010-11-23 2011-11-22 Novos agonistas do recetor de angiotensina tipo 2 (at2) e sua utilização

Country Status (19)

Country Link
US (4) US9290540B2 (pt)
EP (2) EP2455388A1 (pt)
JP (2) JP5837087B2 (pt)
KR (1) KR101512916B1 (pt)
CN (1) CN103314006B (pt)
AU (1) AU2011332397B2 (pt)
CA (1) CA2818299C (pt)
CY (1) CY1119036T1 (pt)
DK (1) DK2643342T3 (pt)
ES (1) ES2632553T3 (pt)
HR (1) HRP20171048T1 (pt)
HU (1) HUE035167T2 (pt)
LT (1) LT2643342T (pt)
NZ (1) NZ610732A (pt)
PL (1) PL2643342T3 (pt)
PT (1) PT2643342T (pt)
RS (1) RS56130B1 (pt)
SI (1) SI2643342T1 (pt)
WO (1) WO2012070936A1 (pt)

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BR102013023224B1 (pt) * 2012-09-14 2023-02-07 Universidade Federal De Minas Gerais PEPTÍDEO (ARGº)N-ANGIOTENSINA-(1-7) E COMPOSIÇÕES FARMACÊUTICAS PARA TRATAMENTO DE DOENÇAS
US8633158B1 (en) * 2012-10-02 2014-01-21 Tarix Pharmaceuticals Ltd. Angiotensin in treating brain conditions
CN105873598A (zh) 2013-07-03 2016-08-17 代表亚利桑那大学的亚利桑那校董会 用于治疗认知功能障碍的方法
CN106535920B (zh) 2014-07-21 2020-10-30 代表亚利桑那大学的亚利桑那校董会 Ang-(1-7)衍生物寡肽及其使用和生产方法
US10183055B2 (en) 2014-07-21 2019-01-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications
WO2016081733A2 (en) * 2014-11-19 2016-05-26 Novopyxis Inc. Compositions and methods for modulating at2r activity
WO2016107879A2 (en) * 2014-12-30 2016-07-07 Vicore Pharma Ab New use of angiotensin ii receptor agonists
EP3820498A1 (en) * 2018-06-14 2021-05-19 University College Cork-National University of Ireland Cork Peptide for disease treatment
CN110333302A (zh) * 2019-06-25 2019-10-15 武汉兴华智慧医药科技有限公司 乙酰半胱氨酸溶液中n，n-二乙酰基羊毛硫氨酸的检测方法
EP4007592A1 (en) 2019-08-02 2022-06-08 LanthioPep B.V. Angiotensin type 2 (at2) receptor agonists for use in the treatment of cancer
KR102488519B1 (ko) * 2020-07-22 2023-01-13 순천대학교 산학협력단 신규 고리형 펜타뎁시펩타이드 화합물 및 이를 유효성분으로 함유하는 상처 치유 또는 재생용 조성물

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JPS6443695A (en) 1987-08-07 1989-02-15 Sun Tech Inc Casing expansion joint device in excavator
US5240928A (en) 1989-07-03 1993-08-31 Merck & Co., Inc. Substituted quinazolinones as angiotensin II antagonists
EP0409332A3 (en) 1989-07-19 1991-08-07 Merck & Co. Inc. Substituted triazoles as angiotensin ii antagonists
US5166206A (en) 1990-03-30 1992-11-24 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
US5091390A (en) 1990-09-20 1992-02-25 E. I. Du Pont De Nemours And Company Treatment of CNS disorders with 4,5,6,7-tetrahydro-1H-imidazo (4,5-)-pyridines and analogs
EP0481614A1 (en) 1990-10-01 1992-04-22 Merck & Co. Inc. Substituted pyridopyrimidinones and related heterocycles as angiotensin II antagonists
US5250521A (en) 1990-12-07 1993-10-05 Merck & Co., Inc. Substituted pyrazolopyrimidines as angiotensin II antagonists
US5260285A (en) 1990-12-07 1993-11-09 Merck & Co., Inc. Substituted imidazopyridazines as angiotensin II antagonists
CA2062558A1 (en) 1991-03-08 1992-09-09 Prasun K. Chakravarty Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists
US5177074A (en) 1991-03-26 1993-01-05 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5252574A (en) 1991-04-26 1993-10-12 Merck & Co., Inc. Angiotensin II antagonists incorporating a substituted thiophene or furan
US5198438A (en) 1991-05-07 1993-03-30 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5312820A (en) 1992-07-17 1994-05-17 Merck & Co., Inc. Substituted carbamoyl and oxycarbonyl derivatives of biphenylmethylamines
WO1994002142A1 (en) 1992-07-17 1994-02-03 Merck & Co., Inc. Substituted biphenylmethylimidazopyridines
US5310929A (en) 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
US5376666A (en) 1992-11-30 1994-12-27 The Du Pont Merck Pharmaceutical Company Angiotension-II receptor blocking, azacycloalkyl or azacycloalkenyl
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WO2008130217A1 (en) * 2006-08-08 2008-10-30 Applied Nanosystems B.V. Cyclic angiotensin analogs
BRPI0800585B8 (pt) 2008-02-13 2021-05-25 Univ Minas Gerais composições farmacêuticas do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7) e uso do peptídeo des-[asp1]-[ala1]-angiotensina-(1-7)

Also Published As

Publication number Publication date
EP2643342A1 (en) 2013-10-02
AU2011332397B2 (en) 2015-11-05
CA2818299A1 (en) 2012-05-31
JP2014503506A (ja) 2014-02-13
JP2016074675A (ja) 2016-05-12
WO2012070936A1 (en) 2012-05-31
CN103314006A (zh) 2013-09-18
US20170283465A1 (en) 2017-10-05
US9707268B2 (en) 2017-07-18
CA2818299C (en) 2018-12-04
EP2643342B1 (en) 2017-04-12
DK2643342T3 (en) 2017-07-24
NZ610732A (en) 2014-05-30
ES2632553T3 (es) 2017-09-14
US20140094400A1 (en) 2014-04-03
KR101512916B1 (ko) 2015-04-16
US20160220632A1 (en) 2016-08-04
EP2455388A1 (en) 2012-05-23
CN103314006B (zh) 2016-04-13
JP5837087B2 (ja) 2015-12-24
US9290540B2 (en) 2016-03-22
US20190135867A1 (en) 2019-05-09
LT2643342T (lt) 2017-09-11
HRP20171048T1 (hr) 2017-10-06
KR20130099178A (ko) 2013-09-05
RS56130B1 (sr) 2017-10-31
CY1119036T1 (el) 2018-01-10
SI2643342T1 (sl) 2017-08-31
PL2643342T3 (pl) 2017-09-29
HUE035167T2 (en) 2018-05-02
US10214563B2 (en) 2019-02-26
AU2011332397A1 (en) 2013-05-02

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