PT2563763E - Composições farmacêuticas que compreendem n-(4-(2-amino-3-cloropiridin-4-iloxi)-3-fluorofenil)-4- etoxi-l-(4-fluorofenil)-2-oxo-1,2-dihidropiridina-3- carboxamida - Google Patents
Composições farmacêuticas que compreendem n-(4-(2-amino-3-cloropiridin-4-iloxi)-3-fluorofenil)-4- etoxi-l-(4-fluorofenil)-2-oxo-1,2-dihidropiridina-3- carboxamida Download PDFInfo
- Publication number
- PT2563763E PT2563763E PT11717917T PT11717917T PT2563763E PT 2563763 E PT2563763 E PT 2563763E PT 11717917 T PT11717917 T PT 11717917T PT 11717917 T PT11717917 T PT 11717917T PT 2563763 E PT2563763 E PT 2563763E
- Authority
- PT
- Portugal
- Prior art keywords
- fluorofenyl
- etoxy
- chloropyridin
- dihydropyridine
- yloxy
- Prior art date
Links
- -1 4- (2-AMINO-3-CHLOROPYRIDIN-4-YLOXY) -3-FLUOROPHENYL Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32971010P | 2010-04-30 | 2010-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2563763E true PT2563763E (pt) | 2015-03-31 |
Family
ID=44209564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT11717917T PT2563763E (pt) | 2010-04-30 | 2011-04-29 | Composições farmacêuticas que compreendem n-(4-(2-amino-3-cloropiridin-4-iloxi)-3-fluorofenil)-4- etoxi-l-(4-fluorofenil)-2-oxo-1,2-dihidropiridina-3- carboxamida |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8911785B2 (https=) |
| EP (1) | EP2563763B1 (https=) |
| JP (1) | JP5820874B2 (https=) |
| KR (1) | KR101897302B1 (https=) |
| CN (1) | CN102971296B (https=) |
| DK (1) | DK2563763T3 (https=) |
| ES (1) | ES2533075T3 (https=) |
| HR (1) | HRP20150105T1 (https=) |
| MY (1) | MY183769A (https=) |
| PH (1) | PH12012502019A1 (https=) |
| PL (1) | PL2563763T3 (https=) |
| PT (1) | PT2563763E (https=) |
| RS (1) | RS53790B1 (https=) |
| SG (1) | SG184891A1 (https=) |
| SI (1) | SI2563763T1 (https=) |
| SM (1) | SMT201500069B (https=) |
| WO (1) | WO2011137274A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104080905B (zh) * | 2011-12-22 | 2016-11-16 | 生命技术公司 | 细胞培养基和方法 |
| KR101545268B1 (ko) | 2015-02-05 | 2015-08-20 | 보령제약 주식회사 | 정제 및 이의 제조방법 |
| WO2016126012A1 (en) * | 2015-02-05 | 2016-08-11 | Boryung Pharmaceutical Co., Ltd | Tablet and method of preparing the same |
| WO2020150307A1 (en) * | 2019-01-15 | 2020-07-23 | The Translational Genomics Research Institute | Phosphonate conjugates and uses thereof |
| US20230257364A1 (en) * | 2022-02-16 | 2023-08-17 | Cmg Pharmaceutical Co., Ltd. | Pyridazinone-based compounds as axl, c-met, and mer inhibitors and methods of use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214344B1 (en) | 1995-06-02 | 2001-04-10 | Genetech, Inc. | Hepatocyte growth factor receptor antagonists and uses thereof |
| ID21762A (id) * | 1996-09-24 | 1999-07-22 | Lilly Co Eli | Formulasi partikel bersaput |
| US7459562B2 (en) | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
| WO2006118210A1 (ja) * | 2005-04-28 | 2006-11-09 | Eisai R & D Management Co., Ltd. | ジヒドロピリジン系化合物の分解を防止する方法 |
| TR200504775A1 (tr) | 2005-11-30 | 2007-10-22 | Esen Beki̇r | Kendinden metal takviyeli pvc pencere ve kapı profilleri |
| PT1808164E (pt) * | 2006-01-05 | 2009-03-17 | Teva Pharma | Método de granulação húmida para a preparação de composições farmacêuticas de aripiprazole |
| US7851489B2 (en) * | 2006-11-08 | 2010-12-14 | Bristol-Myers Squibb Company | Pyridinone compounds |
| US20080260837A1 (en) * | 2007-04-20 | 2008-10-23 | Qpharma, L.L.C. | Physically stable aqueous suspensions of active pharmaceuticals |
| US8263652B2 (en) * | 2007-10-31 | 2012-09-11 | Sk Biopharmaceuticals Co., Ltd. | Stabilized pediatric suspension of carisbamate |
| JP5693239B2 (ja) | 2008-01-23 | 2015-04-01 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 4−ピリジノン化合物および癌についてのその使用 |
-
2011
- 2011-04-29 CN CN201180032341.1A patent/CN102971296B/zh active Active
- 2011-04-29 RS RS20150055A patent/RS53790B1/sr unknown
- 2011-04-29 PH PH1/2012/502019A patent/PH12012502019A1/en unknown
- 2011-04-29 EP EP11717917.6A patent/EP2563763B1/en active Active
- 2011-04-29 WO PCT/US2011/034417 patent/WO2011137274A1/en not_active Ceased
- 2011-04-29 KR KR1020127031220A patent/KR101897302B1/ko active Active
- 2011-04-29 DK DK11717917.6T patent/DK2563763T3/en active
- 2011-04-29 JP JP2013508267A patent/JP5820874B2/ja active Active
- 2011-04-29 PT PT11717917T patent/PT2563763E/pt unknown
- 2011-04-29 ES ES11717917.6T patent/ES2533075T3/es active Active
- 2011-04-29 HR HRP20150105AT patent/HRP20150105T1/hr unknown
- 2011-04-29 MY MYPI2012004708A patent/MY183769A/en unknown
- 2011-04-29 PL PL11717917T patent/PL2563763T3/pl unknown
- 2011-04-29 SI SI201130405T patent/SI2563763T1/sl unknown
- 2011-04-29 US US13/643,561 patent/US8911785B2/en active Active
- 2011-04-29 SG SG2012076865A patent/SG184891A1/en unknown
-
2014
- 2014-09-15 US US14/486,139 patent/US9233948B2/en active Active
-
2015
- 2015-03-18 SM SM201500069T patent/SMT201500069B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2533075T3 (es) | 2015-04-07 |
| US20150065719A1 (en) | 2015-03-05 |
| SG184891A1 (en) | 2012-11-29 |
| US8911785B2 (en) | 2014-12-16 |
| KR20130100237A (ko) | 2013-09-10 |
| US20130039989A1 (en) | 2013-02-14 |
| RS53790B1 (sr) | 2015-06-30 |
| EP2563763A1 (en) | 2013-03-06 |
| PH12012502019A1 (en) | 2017-08-18 |
| WO2011137274A1 (en) | 2011-11-03 |
| DK2563763T3 (en) | 2015-04-07 |
| HK1179260A1 (en) | 2013-09-27 |
| KR101897302B1 (ko) | 2018-09-11 |
| SI2563763T1 (sl) | 2015-03-31 |
| JP5820874B2 (ja) | 2015-11-24 |
| EP2563763B1 (en) | 2014-12-31 |
| SMT201500069B (it) | 2015-05-05 |
| HRP20150105T1 (hr) | 2015-03-13 |
| CN102971296A (zh) | 2013-03-13 |
| JP2013525455A (ja) | 2013-06-20 |
| AU2011245269A1 (en) | 2012-12-20 |
| PL2563763T3 (pl) | 2015-06-30 |
| US9233948B2 (en) | 2016-01-12 |
| MY183769A (en) | 2021-03-12 |
| CN102971296B (zh) | 2015-11-25 |
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