PT2517700E - Cocristais farmaceuticamente aceitáveis de n-[2-(7-metoxi- 1-naftil)etil]acetamida e métodos para a sua preparação - Google Patents
Cocristais farmaceuticamente aceitáveis de n-[2-(7-metoxi- 1-naftil)etil]acetamida e métodos para a sua preparaçãoInfo
- Publication number
- PT2517700E PT2517700E PT110750734T PT11075073T PT2517700E PT 2517700 E PT2517700 E PT 2517700E PT 110750734 T PT110750734 T PT 110750734T PT 11075073 T PT11075073 T PT 11075073T PT 2517700 E PT2517700 E PT 2517700E
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutically acceptable
- methods
- acetamide
- naphthyl
- methoxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/145—Maleic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/265—Citric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11075073.4A EP2517700B1 (en) | 2011-04-28 | 2011-04-28 | Pharmaceutically acceptable cocrystals of N-[2-(7-methoxy-1-naphthyl]acetamide and methods of their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2517700E true PT2517700E (pt) | 2013-10-14 |
Family
ID=44519907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT110750734T PT2517700E (pt) | 2011-04-28 | 2011-04-28 | Cocristais farmaceuticamente aceitáveis de n-[2-(7-metoxi- 1-naftil)etil]acetamida e métodos para a sua preparação |
Country Status (16)
Country | Link |
---|---|
US (1) | US8927771B2 (pt) |
EP (1) | EP2517700B1 (pt) |
JP (1) | JP5770928B2 (pt) |
KR (1) | KR20140008370A (pt) |
CN (1) | CN103501777B (pt) |
BR (1) | BR112013023471A2 (pt) |
EA (1) | EA024422B1 (pt) |
ES (1) | ES2429348T3 (pt) |
IL (1) | IL228916A (pt) |
MX (1) | MX342807B (pt) |
PL (1) | PL2517700T3 (pt) |
PT (1) | PT2517700E (pt) |
RS (1) | RS52982B (pt) |
UA (1) | UA111844C2 (pt) |
WO (1) | WO2012146371A1 (pt) |
ZA (1) | ZA201307688B (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH12012000132B1 (en) | 2011-06-09 | 2014-10-20 | Servier Lab | New co-crystals of agomelatine, a process for their preparation and pharmaceutical compositions containing them |
EP2551257A1 (en) * | 2011-07-28 | 2013-01-30 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of agomelatine with co-crystal-formers |
WO2013170738A1 (zh) * | 2012-05-14 | 2013-11-21 | 上海右手医药科技开发有限公司 | 阿戈美拉汀酸根复合物及其制备方法和用途 |
US10098859B2 (en) | 2012-09-05 | 2018-10-16 | Amri Ssci, Llc | Cocrystals of p-coumaric acid |
EP2743255B1 (en) | 2012-12-17 | 2016-06-22 | Dr. Reddy's Laboratories Ltd. | Cocrystal of agomelatine with phosphoric acid |
PL2810656T3 (pl) | 2013-06-06 | 2018-01-31 | Zentiva Ks | Preparaty agomelatyny zawierające agomelatynę w postaci kokryształów |
EP2810647A1 (en) * | 2013-06-06 | 2014-12-10 | Zentiva, a.s. | Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid |
FR3012142B1 (fr) * | 2013-10-17 | 2016-07-15 | Servier Lab | Nouveaux complexes d'agomelatine et d'acides sulfoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
SI3027588T1 (sl) * | 2013-07-29 | 2020-08-31 | Les Laboratoires Servier | Kompleksi agomelatina in sulfonskih kislin, postopek za pripravo le-teh in farmacevtskih sestavkov, ki jih vsebujejo |
WO2015013865A1 (en) * | 2013-07-29 | 2015-02-05 | Les Laboratoires Servier | Agomelatine sulfonic acids complexes and preparation thereof |
WO2015013903A1 (en) * | 2013-07-31 | 2015-02-05 | Les Laboratoires Servier | NEW AGOMELATINE p-TOLUENESULFONIC ACID CO-CRYSTAL FORMS AND PREPARATION THEREOF |
ES2734562T3 (es) * | 2013-07-31 | 2019-12-10 | Servier Lab | Co-cristales de agomelatina y ácido p-toluensulfónico, su procedimiento de preparación y composiciones farmacéuticas que los contienen |
CN105473551B (zh) * | 2013-07-31 | 2019-01-11 | 法国施维雅药厂 | 阿戈美拉汀和对甲苯磺酸的共晶的新形式、其制备方法和包含其的药物组合物 |
KR101404836B1 (ko) | 2014-03-21 | 2014-06-09 | 순천향대학교 산학협력단 | 아고멜라틴의 공결정 및 그의 제조방법 |
KR101470794B1 (ko) | 2014-06-30 | 2014-12-08 | 순천향대학교 산학협력단 | 아고멜라틴 공결정의 제조 방법 및 이를 포함하는 조성물 |
ES2959460T3 (es) | 2015-03-31 | 2024-02-26 | Fis Fabbrica Italiana Sintetici Spa | Forma sólida de agomelatina |
WO2017115284A1 (en) * | 2015-12-28 | 2017-07-06 | Leiutis Pharmaceuticals Pvt, Ltd. | Novel co-crystal forms of agomelatine |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2514733A1 (en) * | 2003-02-28 | 2004-09-16 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
AR047553A1 (es) * | 2003-07-04 | 2006-01-25 | Lundbeck & Co As H | La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina |
WO2008035177A2 (en) * | 2006-09-18 | 2008-03-27 | Copharm | Combination of mt1 and mt2 melatonin receptor agonists and a norepinephrine/dopamine reuptake inhibitor |
CN101481321B (zh) * | 2009-02-27 | 2012-04-18 | 上海医药工业研究院 | 阿戈美拉汀卤化氢复合物及其制备方法 |
CN102106806B (zh) * | 2009-12-29 | 2013-04-17 | 上海中西制药有限公司 | 一种固体制剂的制备方法及所得固体制剂 |
WO2012046253A2 (en) * | 2010-10-08 | 2012-04-12 | Msn Laboratories Limited | Process for the preparation of n-[2- (7-methoxy-l-naphthyl) ethyl] acetamide and its novel crystalline forms |
PH12012000132B1 (en) * | 2011-06-09 | 2014-10-20 | Servier Lab | New co-crystals of agomelatine, a process for their preparation and pharmaceutical compositions containing them |
-
2011
- 2011-04-28 EP EP11075073.4A patent/EP2517700B1/en not_active Not-in-force
- 2011-04-28 PL PL11075073T patent/PL2517700T3/pl unknown
- 2011-04-28 ES ES11075073T patent/ES2429348T3/es active Active
- 2011-04-28 PT PT110750734T patent/PT2517700E/pt unknown
- 2011-04-28 RS RS20130436A patent/RS52982B/en unknown
-
2012
- 2012-04-25 UA UAA201313793A patent/UA111844C2/uk unknown
- 2012-04-25 EA EA201391574A patent/EA024422B1/ru not_active IP Right Cessation
- 2012-04-25 MX MX2013012103A patent/MX342807B/es active IP Right Grant
- 2012-04-25 BR BR112013023471A patent/BR112013023471A2/pt not_active Application Discontinuation
- 2012-04-25 CN CN201280020790.9A patent/CN103501777B/zh not_active Expired - Fee Related
- 2012-04-25 WO PCT/EP2012/001761 patent/WO2012146371A1/en active Application Filing
- 2012-04-25 KR KR1020137024023A patent/KR20140008370A/ko not_active Application Discontinuation
- 2012-04-25 JP JP2014506792A patent/JP5770928B2/ja not_active Expired - Fee Related
- 2012-04-25 US US14/114,211 patent/US8927771B2/en not_active Expired - Fee Related
-
2013
- 2013-10-16 ZA ZA2013/07688A patent/ZA201307688B/en unknown
- 2013-10-16 IL IL228916A patent/IL228916A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
UA111844C2 (uk) | 2016-06-24 |
EA024422B1 (ru) | 2016-09-30 |
US8927771B2 (en) | 2015-01-06 |
BR112013023471A2 (pt) | 2016-12-13 |
CN103501777A (zh) | 2014-01-08 |
EP2517700A1 (en) | 2012-10-31 |
JP5770928B2 (ja) | 2015-08-26 |
EA201391574A1 (ru) | 2014-04-30 |
US20140051887A1 (en) | 2014-02-20 |
PL2517700T3 (pl) | 2013-12-31 |
MX2013012103A (es) | 2014-01-24 |
ES2429348T3 (es) | 2013-11-14 |
IL228916A (en) | 2016-05-31 |
KR20140008370A (ko) | 2014-01-21 |
JP2014522388A (ja) | 2014-09-04 |
WO2012146371A1 (en) | 2012-11-01 |
RS52982B (en) | 2014-02-28 |
IL228916A0 (en) | 2013-12-31 |
ZA201307688B (en) | 2015-04-29 |
CN103501777B (zh) | 2015-08-19 |
EP2517700B1 (en) | 2013-07-17 |
MX342807B (es) | 2016-10-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT2517700E (pt) | Cocristais farmaceuticamente aceitáveis de n-[2-(7-metoxi- 1-naftil)etil]acetamida e métodos para a sua preparação | |
IL260297A (en) | Process for preparing n-[5-(5,3-difluoro-benzyl)-h1-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino )–benzamide | |
EP2705023A4 (en) | PROCESSES FOR THE PREPARATION OF N- [2- (7-METHOXY-1-NAPHTHYLLELYHYL) ACETAMIDE | |
MD20120050A2 (en) | New agomelatine cocrystals, process for their preparation and pharmaceutical compositions containing them | |
IN2015KN00262A (pt) | ||
WO2014041565A3 (en) | Improved process for preparation of vilanterol and intermediates thereof | |
WO2013098833A3 (en) | Processes and intermediates for preparing rivaroxaban | |
HK1197414A1 (zh) | 雌甾- -四烯- -甲酰胺衍生物、其製備方法、包含其的藥物製劑及其用於製備藥物的用途 | |
IL222999A (en) | Process for the preparation of pluromutilins, intermediates and pharmaceutical preparations containing pluromutilins | |
CL2011001405A1 (es) | Procedimiento para la preparacion de n-[2-(7-metoxi-1-naftil)etil]acetamida, agometalina. | |
WO2013093931A3 (en) | Novel prodrugs of phenolic drugs | |
HUP1100701A2 (en) | Novel process for the preparation of travoprost | |
EP2697238A4 (en) | SOLID FORMS OF ANTIRETROVIRUS COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITION | |
MX2012008413A (es) | Composicion novedosa de retigabina. | |
EP2773610A4 (en) | DEODODING PROCESS FOR PREPARING AROMATIC 3,5-DISUBSTITUTED 2,4,6-TRIJOD AMINE COMPOUNDS | |
NZ701103A (en) | Solid state forms of n-((s)-2,3-dihydroxy-propyl)-3-(2-fluoro-4-iodo-phenylamino)-isonicotinamide | |
MA35002B1 (fr) | Forme cristalline delta du sel d'arginine du périndopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent | |
HK1178881A1 (en) | New co-crystals of agomelatine, a process for their preparation and pharmaceutical compositions containing them | |
GEP20094746B (en) | Use of agomelatine to obtain medication aimed at treating smith-magenis syndrome | |
EA201201123A1 (ru) | Применение агомелатина для получения лекарственных средств, предназначенных для лечения обсессивно-компульсивного расстройства (окр) | |
IL222799A0 (en) | Novel process for the preparation of nitrogen substituted aminotetralins derivatives | |
EP2677868A4 (en) | PHARMACEUTICAL COMPOSITIONS OF MARAVIROC AND METHOD OF PREPARING THEM | |
MD20160072A2 (ro) | Procedeu nou de sinteză a 7-metoxi-naftalină-1-carbaldehidei şi aplicarea acesteia în sinteza agomelatinei | |
IN2013MU01336A (pt) | ||
PL396024A1 (pl) | Sposób wytwarzania 4,2',4' -trihydroksy-6'-metoksy-3'-prenylo-α,ß-dihydrochalkonu |