PT2493508T - Composições farmacêuticas transdérmicas compreendendo agentes activos - Google Patents

Composições farmacêuticas transdérmicas compreendendo agentes activos

Info

Publication number
PT2493508T
PT2493508T PT10768983T PT10768983T PT2493508T PT 2493508 T PT2493508 T PT 2493508T PT 10768983 T PT10768983 T PT 10768983T PT 10768983 T PT10768983 T PT 10768983T PT 2493508 T PT2493508 T PT 2493508T
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
active agents
transdermal pharmaceutical
transdermal
agents
Prior art date
Application number
PT10768983T
Other languages
English (en)
Portuguese (pt)
Inventor
Masini-Eteve Valérie
Canet Denis
Original Assignee
Besins Healthcare Lu Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Besins Healthcare Lu Sarl filed Critical Besins Healthcare Lu Sarl
Publication of PT2493508T publication Critical patent/PT2493508T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
PT10768983T 2009-10-27 2010-10-27 Composições farmacêuticas transdérmicas compreendendo agentes activos PT2493508T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25524109P 2009-10-27 2009-10-27
EP09178762 2009-12-10

Publications (1)

Publication Number Publication Date
PT2493508T true PT2493508T (pt) 2018-10-09

Family

ID=42102488

Family Applications (2)

Application Number Title Priority Date Filing Date
PT181636598T PT3360575T (pt) 2009-10-27 2010-10-27 Composições farmacêuticas transdérmicas compreendendo agentes ativos
PT10768983T PT2493508T (pt) 2009-10-27 2010-10-27 Composições farmacêuticas transdérmicas compreendendo agentes activos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT181636598T PT3360575T (pt) 2009-10-27 2010-10-27 Composições farmacêuticas transdérmicas compreendendo agentes ativos

Country Status (23)

Country Link
US (2) US10080760B2 (ja)
EP (2) EP2493508B1 (ja)
JP (1) JP5727494B2 (ja)
CN (1) CN102686240B (ja)
AU (1) AU2010311523B2 (ja)
BR (1) BR112012010083B8 (ja)
CA (1) CA2778689C (ja)
CY (1) CY1120888T1 (ja)
DK (2) DK3360575T3 (ja)
ES (2) ES2685313T3 (ja)
FI (1) FI3360575T3 (ja)
HR (2) HRP20230482T1 (ja)
HU (2) HUE062026T2 (ja)
IL (1) IL219236A (ja)
LT (2) LT3360575T (ja)
PL (2) PL2493508T3 (ja)
PT (2) PT3360575T (ja)
RS (2) RS57596B1 (ja)
RU (2) RU2639087C2 (ja)
SI (2) SI2493508T1 (ja)
TR (1) TR201811600T4 (ja)
WO (1) WO2011051354A2 (ja)
ZA (1) ZA201202855B (ja)

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US10080760B2 (en) 2009-10-27 2018-09-25 Besins Healthcare Luxembourg Sarl Transdermal pharmaceutical compositions comprising active agents
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US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
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RU2751037C1 (ru) * 2020-04-03 2021-07-07 Богдан Иванович Асатуров Фармацевтическая композиция на основе аутобиокомпонентов мочи человека для трансдермального применения с лечебной или косметической целью
CN111803469B (zh) * 2020-07-15 2022-08-12 浙江海阁堂医药有限公司 一种含雌二醇透皮吸收缓释贴片及其制备方法
CN113730339B (zh) * 2021-09-17 2023-08-22 中国药科大学 一种黄体酮缓释组合物及其应用
CN117545474A (zh) * 2021-11-08 2024-02-09 李维庸 一种用于向患者递送药物的透皮给药系统

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Also Published As

Publication number Publication date
SI2493508T1 (sl) 2018-10-30
US10080760B2 (en) 2018-09-25
RS57596B1 (sr) 2018-11-30
US11040043B2 (en) 2021-06-22
RS64190B1 (sr) 2023-06-30
CA2778689C (en) 2019-06-11
ES2685313T3 (es) 2018-10-08
HRP20230482T1 (hr) 2023-10-27
EP3360575B1 (en) 2023-04-19
ES2945590T3 (es) 2023-07-04
SI3360575T1 (sl) 2023-07-31
WO2011051354A3 (en) 2012-03-01
JP5727494B2 (ja) 2015-06-03
HUE062026T2 (hu) 2023-09-28
EP2493508B1 (en) 2018-07-18
PL2493508T3 (pl) 2018-11-30
PT3360575T (pt) 2023-05-15
CA2778689A1 (en) 2011-05-05
WO2011051354A2 (en) 2011-05-05
US20190160077A1 (en) 2019-05-30
DK2493508T3 (en) 2018-09-03
EP3360575A1 (en) 2018-08-15
HRP20181346T1 (hr) 2018-10-19
CN102686240B (zh) 2015-05-27
EP2493508A2 (en) 2012-09-05
HUE039200T2 (hu) 2018-12-28
BR112012010083B1 (pt) 2021-05-18
PL3360575T3 (pl) 2023-06-05
CY1120888T1 (el) 2019-12-11
US20110098258A1 (en) 2011-04-28
AU2010311523B2 (en) 2013-10-17
RU2017131709A (ru) 2019-02-06
TR201811600T4 (tr) 2018-09-21
IL219236A0 (en) 2012-06-28
LT3360575T (lt) 2023-06-12
IL219236A (en) 2016-02-29
AU2010311523A1 (en) 2012-05-17
ZA201202855B (en) 2013-06-26
RU2017131709A3 (ja) 2020-10-21
BR112012010083B8 (pt) 2021-08-31
BR112012010083A2 (pt) 2020-10-27
DK3360575T3 (da) 2023-05-08
CN102686240A (zh) 2012-09-19
FI3360575T3 (fi) 2023-05-05
JP2013508444A (ja) 2013-03-07
RU2639087C2 (ru) 2017-12-19
WO2011051354A4 (en) 2012-04-26
RU2012121708A (ru) 2013-12-10
LT2493508T (lt) 2018-10-25

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