PT2493487T - Composição para induzir uma tolerância imunitária específica - Google Patents
Composição para induzir uma tolerância imunitária específicaInfo
- Publication number
- PT2493487T PT2493487T PT107689796T PT10768979T PT2493487T PT 2493487 T PT2493487 T PT 2493487T PT 107689796 T PT107689796 T PT 107689796T PT 10768979 T PT10768979 T PT 10768979T PT 2493487 T PT2493487 T PT 2493487T
- Authority
- PT
- Portugal
- Prior art keywords
- composition
- specific immune
- immune tolerance
- induce specific
- induce
- Prior art date
Links
- 230000006058 immune tolerance Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46433—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Surgery (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25525009P | 2009-10-27 | 2009-10-27 | |
| US32551110P | 2010-04-19 | 2010-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2493487T true PT2493487T (pt) | 2016-11-08 |
Family
ID=43447351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT107689796T PT2493487T (pt) | 2009-10-27 | 2010-10-27 | Composição para induzir uma tolerância imunitária específica |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20120207745A1 (ja) |
| EP (1) | EP2493487B1 (ja) |
| JP (1) | JP5944318B2 (ja) |
| KR (1) | KR101823627B1 (ja) |
| CN (1) | CN102596208B (ja) |
| AU (1) | AU2010311515B2 (ja) |
| CA (1) | CA2778669C (ja) |
| DK (1) | DK2493487T3 (ja) |
| ES (1) | ES2600932T3 (ja) |
| HR (1) | HRP20161223T1 (ja) |
| HU (1) | HUE029150T2 (ja) |
| IL (1) | IL219288A (ja) |
| PL (1) | PL2493487T3 (ja) |
| PT (1) | PT2493487T (ja) |
| RU (1) | RU2012121865A (ja) |
| WO (1) | WO2011051346A1 (ja) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2919804B1 (fr) | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| JP6017422B2 (ja) | 2010-08-10 | 2016-11-02 | エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ（ウペエフエル）Ｅｃｏｌｅ Ｐｏｌｙｔｅｃｈｎｉｑｕｅ Ｆｅｄｅｒａｌｅ ｄｅ Ｌａｕｓａｎｎｅ （ＥＰＦＬ） | 赤血球結合療法 |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| LT2768942T (lt) | 2011-10-17 | 2020-04-10 | Massachusetts Institute Of Technology | Pristatymas į ląstelės vidų |
| NZ722352A (en) | 2012-02-15 | 2022-05-27 | Ecole Polytechnique Fed Lausanne Epfl | Erythrocyte-binding therapeutics |
| JP2015511628A (ja) * | 2012-04-02 | 2015-04-20 | ユニバーシティ オブ ブリストル | 寛容化誘導組成物 |
| KR102304167B1 (ko) | 2013-08-16 | 2021-09-24 | 메사추세츠 인스티튜트 오브 테크놀로지 | 세포로의 선택적 물질 전달 |
| JP6702866B2 (ja) | 2013-11-18 | 2020-06-03 | ルビウス セラピューティクス， インコーポレイテッド | 合成膜−レシーバー複合体 |
| FR3017299B1 (fr) | 2014-02-12 | 2018-05-18 | Erytech Pharma | Composition pharmaceutique comprenant des erythrocytes encapsulant une enzyme a plp et son cofacteur |
| ES2874884T3 (es) * | 2014-02-21 | 2021-11-05 | Ecole Polytechnique Fed De Lausanne Epfl Epfl Tto | Compuestos terapéuticos dirigidos a la glucosa |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| JP6735233B2 (ja) | 2014-04-01 | 2020-08-05 | ルビウス セラピューティクス， インコーポレイテッド | 免疫調節方法及び組成物 |
| RU2020139190A (ru) | 2014-10-31 | 2021-01-26 | Массачусетс Инститьют Оф Текнолоджи | Доставка биомолекул в клетки иммунной системы |
| JP6846345B2 (ja) | 2014-11-14 | 2021-03-24 | マサチューセッツ インスティテュート オブ テクノロジー | 破壊及び場による細胞への化合物及び組成物の送達 |
| EP3245294A4 (en) | 2015-01-12 | 2018-05-30 | Massachusetts Institute of Technology | Gene editing through microfluidic delivery |
| GB201508025D0 (en) | 2015-05-11 | 2015-06-24 | Ucl Business Plc | Fabry disease gene therapy |
| JP6925984B2 (ja) | 2015-07-09 | 2021-08-25 | マサチューセッツ インスティテュート オブ テクノロジー | 無核細胞への物質の送達 |
| WO2017041051A1 (en) | 2015-09-04 | 2017-03-09 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to cells comprising a cell wall |
| SI3402491T1 (sl) | 2016-01-11 | 2022-05-31 | Rubius Therapeutics, Inc. | Sestavki in postopki v zvezi z multimodalnimi terapevtskimi celičnimi sistemi za indikacije raka |
| SG11201809437TA (en) * | 2016-05-03 | 2018-11-29 | Sqz Biotechnologies Co | Intracellular delivery of biomolecules to induce tolerance |
| US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| US20200247903A1 (en) * | 2017-10-20 | 2020-08-06 | Csl Ltd. | Method |
| BR112021016903A2 (pt) | 2019-02-28 | 2021-11-03 | Sqz Biotechnologies Co | Administração de biomoléculas a pbmcs para modificação de uma resposta imune |
| WO2020210162A1 (en) | 2019-04-08 | 2020-10-15 | Sqz Biotechnologies Company | Cartridge for use in a system for delivery of a payload into a cell |
| WO2021228832A1 (en) | 2020-05-11 | 2021-11-18 | Erytech Pharma | Red cell extracellular vesicles (rcevs) containing cargoes and methods of use and production thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5482945A (en) * | 1992-12-22 | 1996-01-09 | American Home Products Corporation | Innovative technique for immunosuppression involving administration of rapamycin loaded formed blood elements |
| IL115744A (en) * | 1994-10-27 | 2000-07-16 | Akzo Nobel Nv | Peptides comprising a subsequence of human cartilage glycoprotein - 39 |
| US20020012667A1 (en) * | 2000-05-16 | 2002-01-31 | Mcmichael John | Method for preventing allograft rejection |
| AU2002249895A1 (en) * | 2001-01-05 | 2002-07-16 | Joslin Diabetes Center, Inc. | Autoantigen composition |
| US7485314B2 (en) * | 2002-05-06 | 2009-02-03 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Induction of antigen specific immunologic tolerance |
| FR2873925B1 (fr) * | 2004-08-05 | 2006-10-13 | Erytech Pharma Soc Par Actions | Procede et dispositif de lyse-rescellement pour l'incorporation de principe actif notamment asparaginase ou inositol hexaphosphate, dans des erythrocytes |
| AU2005316503A1 (en) * | 2004-12-17 | 2006-06-22 | Dynavax Technologies Corporation | Methods and compositions for induction or promotion of immune tolerance |
| KR20100022022A (ko) * | 2007-04-24 | 2010-02-26 | 다이아미드 쎄라퓨틱스 아베 | 자가면역 질환 및 암을 치료하기 위한 의약 및 방법 |
| EP2150254A4 (en) * | 2007-04-26 | 2010-11-10 | Amicus Therapeutics Inc | DOSAGES FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES WITH PHARMACOLOGICAL CHAPTERONES |
| FR2919804B1 (fr) * | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
| GB0909754D0 (en) * | 2009-06-05 | 2009-07-22 | Magnani Mauro | Drug delivery systems |
-
2010
- 2010-10-27 EP EP10768979.6A patent/EP2493487B1/en active Active
- 2010-10-27 DK DK10768979.6T patent/DK2493487T3/en active
- 2010-10-27 US US13/503,955 patent/US20120207745A1/en not_active Abandoned
- 2010-10-27 WO PCT/EP2010/066269 patent/WO2011051346A1/en active Application Filing
- 2010-10-27 CA CA2778669A patent/CA2778669C/en active Active
- 2010-10-27 KR KR1020127013462A patent/KR101823627B1/ko active IP Right Grant
- 2010-10-27 JP JP2012535811A patent/JP5944318B2/ja active Active
- 2010-10-27 ES ES10768979.6T patent/ES2600932T3/es active Active
- 2010-10-27 PL PL10768979T patent/PL2493487T3/pl unknown
- 2010-10-27 HU HUE10768979A patent/HUE029150T2/hu unknown
- 2010-10-27 CN CN201080048552.XA patent/CN102596208B/zh active Active
- 2010-10-27 AU AU2010311515A patent/AU2010311515B2/en active Active
- 2010-10-27 PT PT107689796T patent/PT2493487T/pt unknown
- 2010-10-27 RU RU2012121865/15A patent/RU2012121865A/ru unknown
-
2012
- 2012-04-19 IL IL219288A patent/IL219288A/en active IP Right Grant
-
2016
- 2016-09-26 HR HRP20161223TT patent/HRP20161223T1/hr unknown
-
2021
- 2021-02-05 US US17/169,357 patent/US20210268082A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL2493487T3 (pl) | 2017-02-28 |
| US20120207745A1 (en) | 2012-08-16 |
| CA2778669C (en) | 2019-04-16 |
| US20210268082A1 (en) | 2021-09-02 |
| IL219288A (en) | 2017-02-28 |
| AU2010311515B2 (en) | 2014-02-20 |
| JP5944318B2 (ja) | 2016-07-05 |
| AU2010311515A1 (en) | 2012-05-17 |
| DK2493487T3 (en) | 2016-12-05 |
| CN102596208A (zh) | 2012-07-18 |
| JP2013508442A (ja) | 2013-03-07 |
| EP2493487B1 (en) | 2016-08-24 |
| CN102596208B (zh) | 2017-06-20 |
| CA2778669A1 (en) | 2011-05-05 |
| KR20120101657A (ko) | 2012-09-14 |
| EP2493487A1 (en) | 2012-09-05 |
| IL219288A0 (en) | 2012-06-28 |
| ES2600932T3 (es) | 2017-02-13 |
| KR101823627B1 (ko) | 2018-01-30 |
| RU2012121865A (ru) | 2013-12-10 |
| HRP20161223T1 (hr) | 2016-11-18 |
| RU2017139244A (ru) | 2019-02-12 |
| RU2017139244A3 (ja) | 2021-02-26 |
| HUE029150T2 (hu) | 2017-02-28 |
| WO2011051346A1 (en) | 2011-05-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL219288A0 (en) | Composition to induce specific immune tolerance | |
| HK1217711A1 (zh) | 特異於鈣粘素- 的抗體 | |
| GB0915782D0 (en) | Improvements in or relating to pointing devices | |
| GB0905863D0 (en) | Novel composition | |
| ZA201107961B (en) | Borinic compositions | |
| ZA201105384B (en) | To be advised | |
| ZA201107838B (en) | Composition | |
| IL216395A0 (en) | Prothrombic complex composition | |
| GB0901966D0 (en) | Composition | |
| EP2394634A4 (en) | HESPERIDO-CONTAINING COMPOSITION | |
| GB0907115D0 (en) | Improvements relating to bras | |
| GB0905657D0 (en) | Improvements in or relating to stairlifts | |
| GB0904941D0 (en) | Composition | |
| EP2444061A4 (en) | COMPOSITION CONTAINING APIGENIN | |
| GB201009275D0 (en) | Improvements in or relating to compositions | |
| GB0903688D0 (en) | Composition | |
| GB201020990D0 (en) | Improvements relating to trams | |
| GB0912768D0 (en) | Novel composition | |
| GB0909994D0 (en) | Improvements in or relating to stairlifts | |
| GB0902959D0 (en) | Composition | |
| GB0902917D0 (en) | Composition | |
| GB201013425D0 (en) | Improvement to packaging | |
| GB2466949B (en) | Improvements relating to containers | |
| GB0908476D0 (en) | Improvements in or relating to compositions | |
| GB0914198D0 (en) | Herbal composition |