PT2493471T - Nova terapia de combinação entérica - Google Patents

Nova terapia de combinação entérica

Info

Publication number
PT2493471T
PT2493471T PT108258435T PT10825843T PT2493471T PT 2493471 T PT2493471 T PT 2493471T PT 108258435 T PT108258435 T PT 108258435T PT 10825843 T PT10825843 T PT 10825843T PT 2493471 T PT2493471 T PT 2493471T
Authority
PT
Portugal
Prior art keywords
combination therapy
novel enteric
enteric combination
novel
therapy
Prior art date
Application number
PT108258435T
Other languages
English (en)
Original Assignee
Borody Thomas J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009905229A external-priority patent/AU2009905229A0/en
Application filed by Borody Thomas J filed Critical Borody Thomas J
Publication of PT2493471T publication Critical patent/PT2493471T/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
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    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
PT108258435T 2009-10-26 2010-10-22 Nova terapia de combinação entérica PT2493471T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU2009905229A AU2009905229A0 (en) 2009-10-26 Novel enteric combination therapy

Publications (1)

Publication Number Publication Date
PT2493471T true PT2493471T (pt) 2020-01-09

Family

ID=43921150

Family Applications (1)

Application Number Title Priority Date Filing Date
PT108258435T PT2493471T (pt) 2009-10-26 2010-10-22 Nova terapia de combinação entérica

Country Status (10)

Country Link
US (9) US8772242B2 (pt)
EP (1) EP2493471B1 (pt)
JP (1) JP2013508428A (pt)
AU (1) AU2010312309B2 (pt)
CA (1) CA2778181A1 (pt)
ES (1) ES2762442T3 (pt)
NZ (1) NZ598716A (pt)
PL (1) PL2493471T3 (pt)
PT (1) PT2493471T (pt)
WO (1) WO2011050397A1 (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1698630E (pt) 2005-03-03 2014-09-15 Alfa Wassermann Spa Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
US8772242B2 (en) * 2009-10-26 2014-07-08 Thomas Julius Borody Therapy for enteric infections
SI3564357T1 (sl) 2010-02-01 2022-09-30 Rebiotix, Inc. Bakterioterapija Clostridium Difficile colitisa
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
WO2012076832A1 (en) * 2010-12-09 2012-06-14 Cipla Limited Suppositories comprising rifaximin
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
US10039777B2 (en) 2012-03-20 2018-08-07 Neuro-Lm Sas Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
EP2991649B1 (en) * 2013-04-30 2020-06-03 Thomas Julius Borody Compositions for treating obsessive-compulsive disorder
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
PL3003330T3 (pl) 2013-06-05 2019-03-29 Rebiotix, Inc. Terapia przywracająca mikrobiota (MRT), kompozycje i sposoby wytwarzania
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
DK3546464T3 (da) 2014-05-12 2020-07-27 Alfasigma Spa Fremstilling og anvendelse af den krystallinske form tau af rifaximin solvateret med degme
WO2015175997A1 (en) * 2014-05-15 2015-11-19 The Trustees Of Columbia University In The City Of New York Methods and pharmaceutical compositions for treating diseases associated with altered sert activity
KR20170052626A (ko) 2014-09-05 2017-05-12 심바이오믹스 세러퓨틱스 엘엘씨 세균질증 치료에 사용하기 위한 세크니다졸
WO2016100203A1 (en) * 2014-12-20 2016-06-23 Gregg John Malcolm Hall Antimicrobial drug synthesis and therapeutic compositions
CA2988082C (en) 2015-06-01 2020-09-29 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
PL3307289T3 (pl) 2015-06-09 2022-01-17 Rebiotix, Inc. Sposoby wytwarzania kompozycji do terapii przywracającej mikrobiotę (mrt)
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
WO2017205302A1 (en) * 2016-05-23 2017-11-30 California Institute Of Technology Regulate gut microbiota to treat neurodegenerative disorders
US20200138794A1 (en) * 2017-08-15 2020-05-07 Thomas Julius Borody Novel parasite therapy
CN110290790A (zh) * 2017-08-31 2019-09-27 消化系统疾病中心 用于治疗强迫症的组合物、装置和方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEP19971086B (en) * 1991-02-22 1997-12-02 Tillotts Pharma Ag Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine
US5523401A (en) * 1991-04-09 1996-06-04 Abbott Laboratories Macrocyclic lactam prokinetic agents
US6861053B1 (en) * 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US7048906B2 (en) * 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
PT971735E (pt) * 1997-04-01 2008-06-02 Borody Thomas J Métodos e composições para tratamento de doença inflamatória do intestino
AUPO665397A0 (en) * 1997-05-07 1997-05-29 Borody, Thomas Julius Novel therapy for constipation
ATE295176T1 (de) * 1997-05-19 2005-05-15 Repligen Corp Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen
JP3449253B2 (ja) * 1998-10-29 2003-09-22 シオノギクオリカプス株式会社 硬質カプセルの製造方法
US20040170617A1 (en) * 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
US20060198815A1 (en) 2001-03-19 2006-09-07 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained release
US20030130171A1 (en) * 2001-10-30 2003-07-10 Schoenhard Grant L. Inhibitors of ABC drug transporters in multidrug resistant microbial cells
US20040077533A1 (en) * 2002-05-23 2004-04-22 Sayada Chalom B. Methods and compositions for treating bacterial infections and diseases associated therewith
JP2006501310A (ja) * 2002-08-29 2006-01-12 アクティブバイオティクス インコーポレイティッド クロストリジウム・ディフィシレの感染およびそれに関係する疾患を治療するための方法および試薬
AU2003273318A1 (en) * 2002-09-12 2004-04-30 University Of Chicago Monitoring and diagnosis of gastric emptying and gastroparesis
US7687075B2 (en) * 2003-11-19 2010-03-30 Salix Pharmaceuticals, Ltd. Colonic purgative composition with soluble binding agent
EP2361620B1 (en) * 2004-02-06 2016-04-06 PHARMATEL (R&D) PTY LIMITED as Trustee for the PHARMATEL (R & D) TRUST Use of aminosalicylates in diarrhoea-predominant irritable bowel syndrome
JP2008500058A (ja) * 2004-03-29 2008-01-10 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニア アルツハイマー病および他の神経変性疾患の発症前または発症後診断の方法および組成物
EP1611879B1 (en) * 2004-07-02 2009-08-12 Novagali Pharma SA Use of emulsions for intra- and periocular injection
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
TW200711649A (en) * 2005-06-17 2007-04-01 Combinatorx Inc Combination therapy for the treatment of immunoinflammatory disorders
US20110136867A1 (en) * 2006-02-02 2011-06-09 Justman Craig J Treatment of Synucleinopathies
US20090093548A1 (en) * 2007-10-05 2009-04-09 Mutual Pharmaceutical Company, Inc Colchine compositions and methods
RU2367458C1 (ru) * 2007-12-26 2009-09-20 Вагиф Султанович Султанов Лекарственное средство, фармацевтическая композиция, ингибитор роста helicobacter pylori и способ проведения антихеликобактерной терапии
CA2716375C (en) * 2008-02-20 2018-05-29 The Children's Hospital Of Philadelphia Genetic alterations associated with autism and the autistic phenotype and methods of use thereof for the diagnosis and treatmemt of autism
EP2259780A2 (en) * 2008-02-28 2010-12-15 Syntropharma Limited Pharmaceutical composition comprising naltrexone
BRPI0918997A2 (pt) * 2008-09-26 2015-12-01 Aska Pharm Co Ltd agente para evitar e/ou tratar um disturbio gastrointestinal funcional.
HUE048293T2 (hu) * 2008-10-02 2020-07-28 Salix Pharmaceuticals Ltd Eljárások hepatikus enkefalopátia kezelésére
BRPI1008058A8 (pt) * 2009-02-11 2018-03-27 Cedars Sinai Medical Center uso de antibióticos para reduzir a probabilidade de desenvolver síndrome do intestino irritável pós-infecciosa
US8772242B2 (en) * 2009-10-26 2014-07-08 Thomas Julius Borody Therapy for enteric infections
US8817519B2 (en) 2012-11-08 2014-08-26 SK Hynix Inc. Integrated circuit including e-fuse array circuit

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US8772242B2 (en) 2014-07-08
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US11471505B2 (en) 2022-10-18
US10517922B2 (en) 2019-12-31
EP2493471A1 (en) 2012-09-05
US11344602B2 (en) 2022-05-31
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US20220288158A1 (en) 2022-09-15
US20170202905A1 (en) 2017-07-20
US20140364373A1 (en) 2014-12-11
US20200297797A1 (en) 2020-09-24
US9095545B2 (en) 2015-08-04
US20150328281A1 (en) 2015-11-19
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US9468663B2 (en) 2016-10-18
US20180110825A1 (en) 2018-04-26
WO2011050397A1 (en) 2011-05-05
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US20120202738A1 (en) 2012-08-09
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US20220226429A1 (en) 2022-07-21

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