PT2460825T - Derivado de um análogo de glp-1 ou os seus sais farcêuticos e a sua utilização - Google Patents

Derivado de um análogo de glp-1 ou os seus sais farcêuticos e a sua utilização

Info

Publication number
PT2460825T
PT2460825T PT10803913T PT10803913T PT2460825T PT 2460825 T PT2460825 T PT 2460825T PT 10803913 T PT10803913 T PT 10803913T PT 10803913 T PT10803913 T PT 10803913T PT 2460825 T PT2460825 T PT 2460825T
Authority
PT
Portugal
Prior art keywords
glp
analogue
derivative
pharmaceutical salts
pharmaceutical
Prior art date
Application number
PT10803913T
Other languages
English (en)
Inventor
Wang Yali
Lü Aifeng
Sun Changan
Yuan Hengli
Original Assignee
Jiangsu Hansoh Pharmaceutical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Hansoh Pharmaceutical Group Co Ltd filed Critical Jiangsu Hansoh Pharmaceutical Group Co Ltd
Publication of PT2460825T publication Critical patent/PT2460825T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT10803913T 2009-07-30 2010-07-29 Derivado de um análogo de glp-1 ou os seus sais farcêuticos e a sua utilização PT2460825T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009101655599A CN101987868B (zh) 2009-07-30 2009-07-30 Glp-1类似物的衍生物或其可药用盐和用途

Publications (1)

Publication Number Publication Date
PT2460825T true PT2460825T (pt) 2018-11-23

Family

ID=43528782

Family Applications (1)

Application Number Title Priority Date Filing Date
PT10803913T PT2460825T (pt) 2009-07-30 2010-07-29 Derivado de um análogo de glp-1 ou os seus sais farcêuticos e a sua utilização

Country Status (16)

Country Link
US (1) US20120129768A1 (pt)
EP (1) EP2460825B1 (pt)
JP (1) JP5768048B2 (pt)
CN (2) CN101987868B (pt)
AU (1) AU2010278466B2 (pt)
BR (1) BR112012001915B1 (pt)
CA (1) CA2769229C (pt)
DK (1) DK2460825T3 (pt)
ES (1) ES2694394T3 (pt)
HK (1) HK1154027A1 (pt)
MX (1) MX2012001186A (pt)
PL (1) PL2460825T3 (pt)
PT (1) PT2460825T (pt)
RU (1) RU2565536C2 (pt)
WO (1) WO2011012080A1 (pt)
ZA (1) ZA201200239B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102229668A (zh) * 2011-06-03 2011-11-02 浙江贝达药业有限公司 一种glp-1衍生物及其应用
CN103566354B (zh) * 2012-07-25 2017-12-05 江苏豪森药业集团有限公司 含有glp‑1类似物的衍生物或其可药用盐的药物组合物
CN103861089B (zh) * 2012-12-17 2019-06-28 江苏豪森药业集团有限公司 Glp-1类似物的衍生物或其可药用盐注射液及其制备方法和用途
JP6991196B2 (ja) * 2016-03-23 2022-02-03 バッヘン・ホールディング・アクチエンゲゼルシャフト グルカゴン様ペプチドを製造するための方法
TW201821434A (zh) 2016-10-10 2018-06-16 法商賽諾菲公司 製備包含親脂性修飾的離胺酸側鏈的肽的方法
CN110291099B (zh) * 2016-12-10 2024-06-21 拜康有限公司 利拉鲁肽的合成
TW201822787A (zh) * 2016-12-30 2018-07-01 大陸商江蘇恆瑞醫藥股份有限公司 一種ｇｌｐ－１類似物的藥物組成物及其製備方法
CN109806386A (zh) * 2017-11-20 2019-05-28 江苏恒瑞医药股份有限公司 Fxr激动剂与glp-1类似物的药物组合物和用途
CN113214382B (zh) * 2018-04-19 2024-01-19 杭州先为达生物科技股份有限公司 酰化的glp-1衍生物
CN115814063A (zh) * 2018-04-19 2023-03-21 杭州先为达生物科技有限公司 Glp-1衍生物及其治疗用途
WO2020104833A1 (en) * 2018-11-19 2020-05-28 4P-Pharma Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production
AU2020256648A1 (en) * 2019-04-11 2021-11-04 Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Multi-receptor agonist and medical use thereof
CN110540587B (zh) * 2019-08-30 2021-03-02 江苏诺泰澳赛诺生物制药股份有限公司 一种有效提高合成肽纯化收率的色谱方法
CN110551203B (zh) * 2019-09-25 2023-02-10 成都奥达生物科技有限公司 一种艾塞那肽类似物
CN110684082B (zh) * 2019-10-08 2021-12-10 江苏诺泰澳赛诺生物制药股份有限公司 Gip和glp-1双激动多肽化合物及药学上可接受的盐与用途
CN114617956B (zh) * 2020-12-10 2023-10-03 江苏中新医药有限公司 一种高效降糖的蛋白质药物
CN114685644A (zh) * 2020-12-29 2022-07-01 苏州康宁杰瑞生物科技有限公司 一种人glp-1多肽变体及其应用
CN114685643A (zh) * 2020-12-29 2022-07-01 苏州康宁杰瑞生物科技有限公司 一种人glp-1多肽变体及其应用
AU2022386489A1 (en) * 2021-11-12 2024-05-23 Fujian Shengdi Pharmaceutical Co., Ltd. Pharmaceutical composition of glp-1 receptor and gip receptor dual agonist, and use thereof
CN116514952B (zh) * 2022-10-13 2024-02-02 江苏师范大学 一类glp-1类似物及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545618A (en) * 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
US5424286A (en) * 1993-05-24 1995-06-13 Eng; John Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
US7235627B2 (en) * 1996-08-30 2007-06-26 Novo Nordisk A/S Derivatives of GLP-1 analogs
EP1826216A1 (en) 1996-08-30 2007-08-29 Novo Nordisk A/S Glp-1 derivatives
EP1056774A1 (en) 1998-02-27 2000-12-06 Novo Nordisk A/S N-terminally truncated glp-1 derivatives
US7399489B2 (en) * 1999-01-14 2008-07-15 Amylin Pharmaceuticals, Inc. Exendin analog formulations
ES2343072T3 (es) * 1999-01-14 2010-07-22 Amylin Pharmaceuticals, Inc. Exendina para la supresion del glucagon.
ES2209885T3 (es) * 1999-05-17 2004-07-01 Conjuchem, Inc. Peptidos insulinotropicos de larga duracion.
EP1076066A1 (en) * 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptides for lowering blood glucose levels
DE602005014969D1 (de) * 2004-04-23 2009-07-30 Conjuchem Biotechnologies Inc Verfahren zur aufreinigung von albumin-konjugaten
DE102004043153B4 (de) * 2004-09-03 2013-11-21 Philipps-Universität Marburg Erfindung betreffend GLP-1 und Exendin
AU2006224537A1 (en) * 2005-03-18 2006-09-21 Novo Nordisk A/S Extended GLP-1 compounds
JP2009532422A (ja) 2006-04-03 2009-09-10 ノボ・ノルデイスク・エー／エス Ｇｌｐ−１ペプチドアゴニスト
US8288339B2 (en) * 2006-04-20 2012-10-16 Amgen Inc. GLP-1 compounds
CN102827284B (zh) * 2006-11-14 2015-07-29 上海仁会生物制药股份有限公司 带有聚乙二醇基团的Exendin或其类似物及其制剂和用途

Also Published As

Publication number Publication date
ES2694394T3 (es) 2018-12-20
EP2460825A4 (en) 2014-03-19
CN101987868B (zh) 2013-09-04
HK1154027A1 (en) 2012-04-20
RU2565536C2 (ru) 2015-10-20
MX2012001186A (es) 2012-06-27
CN101987868A (zh) 2011-03-23
ZA201200239B (en) 2012-09-26
AU2010278466B2 (en) 2014-10-30
WO2011012080A1 (zh) 2011-02-03
EP2460825B1 (en) 2018-08-22
CN102421797A (zh) 2012-04-18
PL2460825T3 (pl) 2019-01-31
EP2460825A1 (en) 2012-06-06
CA2769229C (en) 2019-12-31
BR112012001915B1 (pt) 2019-11-12
CN102421797B (zh) 2014-12-31
JP5768048B2 (ja) 2015-08-26
DK2460825T3 (en) 2018-11-19
BR112012001915A2 (pt) 2016-11-08
JP2013500278A (ja) 2013-01-07
CA2769229A1 (en) 2011-02-03
US20120129768A1 (en) 2012-05-24
AU2010278466A1 (en) 2012-03-15
RU2012105355A (ru) 2013-09-10

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