PT2342182E - Derivados de isoquinolinona como antagonistas de nk3 - Google Patents
Derivados de isoquinolinona como antagonistas de nk3Info
- Publication number
- PT2342182E PT2342182E PT97762850T PT09776285T PT2342182E PT 2342182 E PT2342182 E PT 2342182E PT 97762850 T PT97762850 T PT 97762850T PT 09776285 T PT09776285 T PT 09776285T PT 2342182 E PT2342182 E PT 2342182E
- Authority
- PT
- Portugal
- Prior art keywords
- antagonists
- isoquinolinone derivatives
- isoquinolinone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200801290 | 2008-09-15 | ||
| DKPA200900010 | 2009-01-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2342182E true PT2342182E (pt) | 2013-02-11 |
Family
ID=41227186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97762850T PT2342182E (pt) | 2008-09-15 | 2009-09-11 | Derivados de isoquinolinona como antagonistas de nk3 |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP2342182B1 (pt) |
| JP (1) | JP5536776B2 (pt) |
| KR (1) | KR101638641B1 (pt) |
| CN (1) | CN102149685B (pt) |
| AR (1) | AR073511A1 (pt) |
| AU (1) | AU2009291309B2 (pt) |
| BR (1) | BRPI0917245B8 (pt) |
| CA (1) | CA2732612C (pt) |
| CL (1) | CL2011000533A1 (pt) |
| CO (1) | CO6351781A2 (pt) |
| CY (1) | CY1113743T1 (pt) |
| DK (1) | DK2342182T3 (pt) |
| EA (1) | EA021581B1 (pt) |
| ES (1) | ES2399177T3 (pt) |
| HR (1) | HRP20130038T1 (pt) |
| IL (1) | IL210236A (pt) |
| MX (1) | MX2011001786A (pt) |
| MY (1) | MY164998A (pt) |
| NZ (1) | NZ591265A (pt) |
| PL (1) | PL2342182T3 (pt) |
| PT (1) | PT2342182E (pt) |
| RS (1) | RS52674B (pt) |
| SI (1) | SI2342182T1 (pt) |
| SM (1) | SMT201300020B (pt) |
| TW (1) | TWI454461B (pt) |
| WO (1) | WO2010028655A1 (pt) |
| ZA (1) | ZA201103119B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008131779A1 (en) | 2007-04-26 | 2008-11-06 | H. Lundbeck A/S | Isoquinolinone derivatives as nk3 antagonists |
| EA201170074A1 (ru) | 2008-06-23 | 2011-10-31 | Х. Лундбекк А/С | Изохинолиноновые производные в качестве антагонистов nk3 |
| MX2011004034A (es) | 2008-10-20 | 2011-05-10 | Lundbeck & Co As H | Derivados de isoquinolinona como antagonistas de nk3. |
| TW201143768A (en) | 2009-12-15 | 2011-12-16 | Lundbeck & Co As H | Pyridone derivatives as NK3 antagonists |
| TW201144311A (en) * | 2010-03-12 | 2011-12-16 | Lundbeck & Co As H | Azaisoquionolinone derivatives as NK3 antagonists |
| CN104203919A (zh) | 2011-11-09 | 2014-12-10 | 艾伯维德国有限责任两合公司 | 可用作10a型磷酸二酯酶的抑制剂的杂环甲酰胺类 |
| CA3098603A1 (en) * | 2018-04-27 | 2019-10-31 | Sojournix, Inc. | Polymorphic and amorphous forms of isoquinolinone and methods of use thereof |
| WO2023152888A1 (ja) * | 2022-02-10 | 2023-08-17 | カルナバイオサイエンス株式会社 | フルオロイソキノリン化合物およびその製造法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9825554D0 (en) * | 1998-11-20 | 1999-01-13 | Smithkline Beecham Spa | Novel Compounds |
| JP2004525183A (ja) * | 2001-04-11 | 2004-08-19 | グラクソスミスクライン・ソシエタ・ペル・アチオニ | Ｎｋ−３およびｎｋ−２受容体アンタゴニストとしてのキノリン−４−カルボキサミド誘導体 |
| GB0509405D0 (en) * | 2005-05-10 | 2005-06-15 | Merck Sharp & Dohme | Therapeutic compounds |
| WO2008131779A1 (en) * | 2007-04-26 | 2008-11-06 | H. Lundbeck A/S | Isoquinolinone derivatives as nk3 antagonists |
-
2009
- 2009-09-11 MY MYPI2011001144A patent/MY164998A/en unknown
- 2009-09-11 WO PCT/DK2009/050237 patent/WO2010028655A1/en active Application Filing
- 2009-09-11 RS RS20130036A patent/RS52674B/en unknown
- 2009-09-11 NZ NZ591265A patent/NZ591265A/xx not_active IP Right Cessation
- 2009-09-11 JP JP2011526372A patent/JP5536776B2/ja not_active Expired - Fee Related
- 2009-09-11 BR BRPI0917245A patent/BRPI0917245B8/pt not_active IP Right Cessation
- 2009-09-11 EA EA201170447A patent/EA021581B1/ru not_active IP Right Cessation
- 2009-09-11 SI SI200930492T patent/SI2342182T1/sl unknown
- 2009-09-11 MX MX2011001786A patent/MX2011001786A/es active IP Right Grant
- 2009-09-11 AU AU2009291309A patent/AU2009291309B2/en not_active Ceased
- 2009-09-11 DK DK09776285.0T patent/DK2342182T3/da active
- 2009-09-11 CA CA2732612A patent/CA2732612C/en not_active Expired - Fee Related
- 2009-09-11 CN CN200980136727.XA patent/CN102149685B/zh not_active Expired - Fee Related
- 2009-09-11 PT PT97762850T patent/PT2342182E/pt unknown
- 2009-09-11 PL PL09776285T patent/PL2342182T3/pl unknown
- 2009-09-11 KR KR1020117005880A patent/KR101638641B1/ko active IP Right Grant
- 2009-09-11 EP EP09776285A patent/EP2342182B1/en active Active
- 2009-09-11 ES ES09776285T patent/ES2399177T3/es active Active
- 2009-09-14 TW TW098130900A patent/TWI454461B/zh not_active IP Right Cessation
- 2009-09-14 AR ARP090103522A patent/AR073511A1/es active IP Right Grant
-
2010
- 2010-12-23 IL IL210236A patent/IL210236A/en active IP Right Grant
-
2011
- 2011-03-04 CO CO11026657A patent/CO6351781A2/es not_active Application Discontinuation
- 2011-03-14 CL CL2011000533A patent/CL2011000533A1/es unknown
- 2011-04-28 ZA ZA2011/03119A patent/ZA201103119B/en unknown
-
2013
- 2013-01-17 HR HRP20130038AT patent/HRP20130038T1/hr unknown
- 2013-02-06 CY CY20131100105T patent/CY1113743T1/el unknown
- 2013-02-13 SM SM201300020T patent/SMT201300020B/xx unknown
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