PT2326350E - Compostos para matar células cancerosas resistentes a taxano, que expressam psma - Google Patents
Compostos para matar células cancerosas resistentes a taxano, que expressam psmaInfo
- Publication number
- PT2326350E PT2326350E PT97892848T PT09789284T PT2326350E PT 2326350 E PT2326350 E PT 2326350E PT 97892848 T PT97892848 T PT 97892848T PT 09789284 T PT09789284 T PT 09789284T PT 2326350 E PT2326350 E PT 2326350E
- Authority
- PT
- Portugal
- Prior art keywords
- taxane
- expressing
- cancer cells
- resistant cancer
- psma
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9530008P | 2008-09-08 | 2008-09-08 | |
US20539509P | 2009-01-20 | 2009-01-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2326350E true PT2326350E (pt) | 2013-12-10 |
Family
ID=41632348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97892848T PT2326350E (pt) | 2008-09-08 | 2009-09-08 | Compostos para matar células cancerosas resistentes a taxano, que expressam psma |
Country Status (8)
Country | Link |
---|---|
US (1) | US9242012B2 (pt) |
EP (2) | EP2326350B1 (pt) |
DK (1) | DK2326350T3 (pt) |
ES (1) | ES2438495T3 (pt) |
HK (1) | HK1159474A1 (pt) |
PL (1) | PL2326350T3 (pt) |
PT (1) | PT2326350E (pt) |
WO (1) | WO2010027513A2 (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
AU2008289108B2 (en) | 2007-08-17 | 2014-09-18 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
DK2326350T3 (da) | 2008-09-08 | 2013-12-16 | Psma Dev Company L L C | Forbindelser til at dræbe psma-udtrykkende, taxanresistente cancerceller |
CA2769444A1 (en) | 2009-05-19 | 2010-11-25 | Aic Blab Company | Composite current collector and methods therefor |
US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
KR102364214B1 (ko) | 2010-11-12 | 2022-02-17 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 공통 전립선 항원, 이것을 암호화하는 핵산 분자, 그리고 이것을 포함하는 백신 및 용도 |
US9687467B2 (en) | 2011-04-04 | 2017-06-27 | Children's Medical Center Corporation | Diagnosis and treatment of taxane-resistant cancers |
JP2014518615A (ja) | 2011-04-22 | 2014-08-07 | エマージェント プロダクト デベロップメント シアトル, エルエルシー | 前立腺特異的膜抗原結合タンパク質および関連組成物ならびに方法 |
NZ703298A (en) * | 2012-06-07 | 2016-04-29 | Ambrx Inc | Prostate-specific membrane antigen antibody drug conjugates |
KR20150023729A (ko) * | 2012-06-14 | 2015-03-05 | 암브룩스, 인코포레이티드 | 핵 수용체 리간드 폴리펩티드에 접합된 항-psma 항체 |
EA201890915A1 (ru) | 2012-11-15 | 2018-09-28 | Эндосайт, Инк. | Конъюгаты для доставки лекарственных средств и способы лечения заболеваний, вызванных клетками, экспрессирующими psma |
JP6908964B2 (ja) * | 2013-10-18 | 2021-07-28 | ピーエスエムエー ディベロップメント カンパニー,エルエルシー | Psmaリガンドコンジュゲートによる併用療法 |
US20150110814A1 (en) * | 2013-10-18 | 2015-04-23 | Psma Development Company, Llc | Combination therapies with psma ligand conjugates |
JP2016535013A (ja) | 2013-10-18 | 2016-11-10 | ドイチェス クレブスフォルシュンクスツェントルム | 前立腺特異的膜抗原(psma)の標識インヒビター、前立腺癌の治療のための画像化剤および薬剤としてのその使用 |
US20150147339A1 (en) | 2013-11-15 | 2015-05-28 | Psma Development Company, Llc | Biomarkers for psma targeted therapy for prostate cancer |
US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
UA126278C2 (uk) | 2015-09-21 | 2022-09-14 | Аптево Рісьорч Енд Девелопмент Ллс | Поліпептиди, які зв'язують cd3 |
MX2019012017A (es) | 2017-04-07 | 2020-02-12 | Juno Therapeutics Inc | Celulas modificadas que expresan antigeno de membrana especifico de prostata (psma) o una forma modificada del mismo y metodos relacionados. |
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DK2326350T3 (da) | 2008-09-08 | 2013-12-16 | Psma Dev Company L L C | Forbindelser til at dræbe psma-udtrykkende, taxanresistente cancerceller |
-
2009
- 2009-09-08 DK DK09789284.8T patent/DK2326350T3/da active
- 2009-09-08 EP EP09789284.8A patent/EP2326350B1/en not_active Not-in-force
- 2009-09-08 ES ES09789284.8T patent/ES2438495T3/es active Active
- 2009-09-08 WO PCT/US2009/005064 patent/WO2010027513A2/en active Application Filing
- 2009-09-08 EP EP13182516.8A patent/EP2727606A3/en not_active Withdrawn
- 2009-09-08 PT PT97892848T patent/PT2326350E/pt unknown
- 2009-09-08 PL PL09789284T patent/PL2326350T3/pl unknown
-
2011
- 2011-02-17 US US13/030,105 patent/US9242012B2/en active Active
- 2011-11-22 HK HK11112651.2A patent/HK1159474A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP2727606A2 (en) | 2014-05-07 |
US9242012B2 (en) | 2016-01-26 |
EP2326350B1 (en) | 2013-09-04 |
HK1159474A1 (en) | 2012-08-03 |
US20110250216A1 (en) | 2011-10-13 |
EP2727606A3 (en) | 2015-09-23 |
DK2326350T3 (da) | 2013-12-16 |
PL2326350T3 (pl) | 2014-03-31 |
WO2010027513A2 (en) | 2010-03-11 |
ES2438495T3 (es) | 2014-01-17 |
WO2010027513A3 (en) | 2010-06-10 |
EP2326350A2 (en) | 2011-06-01 |
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