PL2326350T3 - Związki do zabijania eksprymujących PSMA, opornych na taksan komórek rakowych - Google Patents
Związki do zabijania eksprymujących PSMA, opornych na taksan komórek rakowychInfo
- Publication number
- PL2326350T3 PL2326350T3 PL09789284T PL09789284T PL2326350T3 PL 2326350 T3 PL2326350 T3 PL 2326350T3 PL 09789284 T PL09789284 T PL 09789284T PL 09789284 T PL09789284 T PL 09789284T PL 2326350 T3 PL2326350 T3 PL 2326350T3
- Authority
- PL
- Poland
- Prior art keywords
- taxane
- expressing
- compounds
- cancer cells
- resistant cancer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9530008P | 2008-09-08 | 2008-09-08 | |
| US20539509P | 2009-01-20 | 2009-01-20 | |
| PCT/US2009/005064 WO2010027513A2 (en) | 2008-09-08 | 2009-09-08 | Methods for killing psma-expressing, taxane-resistant cancer cells |
| EP09789284.8A EP2326350B1 (en) | 2008-09-08 | 2009-09-08 | Compounds for killing psma-expressing, taxane-resistant cancer cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2326350T3 true PL2326350T3 (pl) | 2014-03-31 |
Family
ID=41632348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09789284T PL2326350T3 (pl) | 2008-09-08 | 2009-09-08 | Związki do zabijania eksprymujących PSMA, opornych na taksan komórek rakowych |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9242012B2 (pl) |
| EP (2) | EP2727606A3 (pl) |
| DK (1) | DK2326350T3 (pl) |
| ES (1) | ES2438495T3 (pl) |
| HK (1) | HK1159474A1 (pl) |
| PL (1) | PL2326350T3 (pl) |
| PT (1) | PT2326350E (pl) |
| WO (1) | WO2010027513A2 (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| SI2187965T1 (sl) | 2007-08-17 | 2020-03-31 | Purdue Research Foundation Office Of Technology Commercialization | Konjugati vezalca ligand-veznika PSMA in metode za uporabo |
| WO2010027513A2 (en) | 2008-09-08 | 2010-03-11 | Psma Development Company, Llc | Methods for killing psma-expressing, taxane-resistant cancer cells |
| US20120183847A1 (en) | 2009-05-19 | 2012-07-19 | Aic Blab | Composite current collector and methods therefor |
| US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| CN106434676B (zh) | 2010-11-12 | 2020-10-23 | 宾夕法尼亚大学托管会 | 共有前列腺抗原、编码所述抗原的核酸分子以及包含所述核酸分子的疫苗及其用途 |
| WO2012138691A2 (en) * | 2011-04-04 | 2012-10-11 | Children's Medical Center Corporation | Diagnosis and treatment of taxane-resistant cancers |
| RU2632647C2 (ru) | 2011-04-22 | 2017-10-06 | Аптево Рисерч Энд Девелопмент Ллс | Белки, связывающие специфический мембранный антиген простаты, и соответствующие композиции и способы |
| MX363116B (es) * | 2012-06-07 | 2019-03-11 | Ambrx Inc | Conjugados anticuerpo-farmaco de antigeno de membrana especifico de prostata. |
| KR20150023729A (ko) * | 2012-06-14 | 2015-03-05 | 암브룩스, 인코포레이티드 | 핵 수용체 리간드 폴리펩티드에 접합된 항-psma 항체 |
| EP2919774A4 (en) | 2012-11-15 | 2016-11-09 | Endocyte Inc | CONJUGATES FOR THE TREATMENT OF DISEASES CAUSED BY PSMA-EXPRESSING CELLS |
| MY194484A (en) | 2013-10-18 | 2022-11-30 | Deutsches Krebsforsch | Labeled Inhibitors of Prostate Specific Membrane Antigen (PSMA), Their use as Imaging Agents and Pharmaceutical Agents for the Treatment of Prostate Cancer |
| WO2015057250A1 (en) * | 2013-10-18 | 2015-04-23 | Psma Development Company, Llc | Combination therapies with psma ligand conjugates |
| JP6908964B2 (ja) * | 2013-10-18 | 2021-07-28 | ピーエスエムエー ディベロップメント カンパニー，エルエルシー | Ｐｓｍａリガンドコンジュゲートによる併用療法 |
| US20150147339A1 (en) | 2013-11-15 | 2015-05-28 | Psma Development Company, Llc | Biomarkers for psma targeted therapy for prostate cancer |
| US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
| MY197562A (en) | 2015-09-21 | 2023-06-23 | Aptevo Res & Development Llc | Cd3 binding polypeptides |
| US20230190796A1 (en) | 2017-04-07 | 2023-06-22 | Juno Therapeutics, Inc. | Engineered cells expressing prostate-specific membrane antigen (psma) or a modified form thereof and related methods |
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-
2009
- 2009-09-08 WO PCT/US2009/005064 patent/WO2010027513A2/en active Application Filing
- 2009-09-08 PT PT97892848T patent/PT2326350E/pt unknown
- 2009-09-08 DK DK09789284.8T patent/DK2326350T3/da active
- 2009-09-08 EP EP13182516.8A patent/EP2727606A3/en not_active Withdrawn
- 2009-09-08 ES ES09789284.8T patent/ES2438495T3/es active Active
- 2009-09-08 EP EP09789284.8A patent/EP2326350B1/en not_active Not-in-force
- 2009-09-08 PL PL09789284T patent/PL2326350T3/pl unknown
-
2011
- 2011-02-17 US US13/030,105 patent/US9242012B2/en active Active
- 2011-11-22 HK HK11112651.2A patent/HK1159474A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2438495T3 (es) | 2014-01-17 |
| EP2326350A2 (en) | 2011-06-01 |
| PT2326350E (pt) | 2013-12-10 |
| WO2010027513A2 (en) | 2010-03-11 |
| EP2727606A3 (en) | 2015-09-23 |
| WO2010027513A3 (en) | 2010-06-10 |
| EP2727606A2 (en) | 2014-05-07 |
| HK1159474A1 (en) | 2012-08-03 |
| DK2326350T3 (da) | 2013-12-16 |
| US9242012B2 (en) | 2016-01-26 |
| EP2326350B1 (en) | 2013-09-04 |
| US20110250216A1 (en) | 2011-10-13 |
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