PT2307409E - Pirrolpiridinas como inibidores de cinase - Google Patents

Pirrolpiridinas como inibidores de cinase Download PDF

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Publication number
PT2307409E
PT2307409E PT97474043T PT09747404T PT2307409E PT 2307409 E PT2307409 E PT 2307409E PT 97474043 T PT97474043 T PT 97474043T PT 09747404 T PT09747404 T PT 09747404T PT 2307409 E PT2307409 E PT 2307409E
Authority
PT
Portugal
Prior art keywords
alkyl
hydrogen
phenyl
mmol
atoms
Prior art date
Application number
PT97474043T
Other languages
English (en)
Portuguese (pt)
Inventor
Bin Wang
James F Blake
Eli M Wallace
Le Huerou Yvan
Indrani W Gunwardana
Peter J Mohr
Mark Chicarelli
Michael Lyon
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40810786&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2307409(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of PT2307409E publication Critical patent/PT2307409E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT97474043T 2008-05-13 2009-05-13 Pirrolpiridinas como inibidores de cinase PT2307409E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5292608P 2008-05-13 2008-05-13

Publications (1)

Publication Number Publication Date
PT2307409E true PT2307409E (pt) 2015-11-04

Family

ID=40810786

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97474043T PT2307409E (pt) 2008-05-13 2009-05-13 Pirrolpiridinas como inibidores de cinase

Country Status (30)

Country Link
US (6) US8178131B2 (enExample)
EP (2) EP2990407B1 (enExample)
JP (2) JP5703212B2 (enExample)
KR (2) KR101657856B1 (enExample)
CN (3) CN104926810B (enExample)
AR (1) AR071717A1 (enExample)
AU (1) AU2009246402B2 (enExample)
BR (1) BRPI0913580B8 (enExample)
CA (1) CA2724262C (enExample)
CL (1) CL2009001152A1 (enExample)
CO (1) CO6321244A2 (enExample)
CR (1) CR11803A (enExample)
CY (1) CY1116692T1 (enExample)
DK (1) DK2307409T3 (enExample)
ES (1) ES2552643T3 (enExample)
HK (1) HK1219950A1 (enExample)
HR (1) HRP20151018T1 (enExample)
HU (1) HUE026160T2 (enExample)
IL (1) IL209258A (enExample)
MX (1) MX2010012449A (enExample)
NZ (1) NZ589318A (enExample)
PH (1) PH12013501779B1 (enExample)
PL (1) PL2307409T3 (enExample)
PT (1) PT2307409E (enExample)
RS (1) RS54358B1 (enExample)
RU (1) RU2517194C2 (enExample)
SI (1) SI2307409T1 (enExample)
TW (2) TWI554512B (enExample)
UA (1) UA111933C2 (enExample)
WO (1) WO2009140320A1 (enExample)

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US8481557B2 (en) 2009-04-11 2013-07-09 Array Biopharma Inc. Method of treatment using checkpoint kinase 1 inhibitors
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CN108912032A (zh) * 2018-08-13 2018-11-30 南通大学 一种（3s，4r）-4-甲基吡咯烷-3-基氨基甲醇叔丁酯盐酸盐的化学合成方法
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JP2023540673A (ja) 2020-07-15 2023-09-26 アイエフエム デュー インコーポレイテッド Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物
EP4274824A1 (en) 2021-01-08 2023-11-15 IFM Due, Inc. Heterobicyclic compounds having an urea or analogue and their compositions for treating conditions associated with sting activity
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ES2392014T3 (es) 2008-01-09 2012-12-03 Array Biopharma, Inc. Pirazolopiridinas como inhibidores de la cinasa
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Also Published As

Publication number Publication date
AU2009246402A1 (en) 2009-11-19
KR101643426B1 (ko) 2016-07-27
JP2015098482A (ja) 2015-05-28
CN104926810A (zh) 2015-09-23
JP2011520896A (ja) 2011-07-21
TWI458727B (zh) 2014-11-01
MX2010012449A (es) 2011-05-25
CL2009001152A1 (es) 2009-10-16
PL2307409T3 (pl) 2016-01-29
AU2009246402B2 (en) 2013-05-23
TW201529573A (zh) 2015-08-01
CN109942575A (zh) 2019-06-28
US20110070317A1 (en) 2011-03-24
US20160368916A1 (en) 2016-12-22
RU2517194C2 (ru) 2014-05-27
HUE026160T2 (en) 2016-05-30
US20150322061A1 (en) 2015-11-12
US9365568B2 (en) 2016-06-14
KR20140093266A (ko) 2014-07-25
TWI554512B (zh) 2016-10-21
AR071717A1 (es) 2010-07-07
CA2724262A1 (en) 2009-11-19
HK1152035A1 (en) 2012-02-17
IL209258A (en) 2017-01-31
US8758830B2 (en) 2014-06-24
CN104926810B (zh) 2019-02-19
KR101657856B1 (ko) 2016-09-19
CN102089307B (zh) 2015-07-01
CA2724262C (en) 2017-08-15
US8178131B2 (en) 2012-05-15
IL209258A0 (en) 2011-01-31
US20140100369A1 (en) 2014-04-10
US20140243520A1 (en) 2014-08-28
CN102089307A (zh) 2011-06-08
TW201002707A (en) 2010-01-16
BRPI0913580B1 (pt) 2020-03-10
DK2307409T3 (en) 2015-09-21
EP2307409A1 (en) 2011-04-13
CO6321244A2 (es) 2011-09-20
BRPI0913580A2 (pt) 2015-10-20
RS54358B1 (sr) 2016-04-28
UA111933C2 (uk) 2016-07-11
BRPI0913580B8 (pt) 2021-05-25
EP2307409B1 (en) 2015-08-12
SI2307409T1 (sl) 2015-11-30
EP2990407B1 (en) 2019-10-16
PH12013501779A1 (en) 2014-08-27
JP5703212B2 (ja) 2015-04-15
KR20110008102A (ko) 2011-01-25
HRP20151018T1 (hr) 2015-10-23
PH12013501779B1 (en) 2019-02-13
US8981085B2 (en) 2015-03-17
NZ589318A (en) 2011-06-30
RU2010150786A (ru) 2012-06-20
CY1116692T1 (el) 2017-03-15
US8545897B2 (en) 2013-10-01
HK1219950A1 (en) 2017-04-21
WO2009140320A1 (en) 2009-11-19
US9969727B2 (en) 2018-05-15
US20130045286A1 (en) 2013-02-21
ES2552643T3 (es) 2015-12-01
CR11803A (es) 2011-02-11
EP2990407A1 (en) 2016-03-02

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