PT1851198E - Pirroles substituídos, composições contendo-os, processo de fabrico e utilização - Google Patents
Pirroles substituídos, composições contendo-os, processo de fabrico e utilização Download PDFInfo
- Publication number
- PT1851198E PT1851198E PT06709274T PT06709274T PT1851198E PT 1851198 E PT1851198 E PT 1851198E PT 06709274 T PT06709274 T PT 06709274T PT 06709274 T PT06709274 T PT 06709274T PT 1851198 E PT1851198 E PT 1851198E
- Authority
- PT
- Portugal
- Prior art keywords
- same
- compositions containing
- substituted pyrroles
- making
- making same
- Prior art date
Links
- 0 *C(NC(C1C(N)=O)NC=C1c(cc1)ccc1NC(Nc1cc(C(F)(F)F)ccc1F)=O)=O Chemical compound *C(NC(C1C(N)=O)NC=C1c(cc1)ccc1NC(Nc1cc(C(F)(F)F)ccc1F)=O)=O 0.000 description 3
- HYBXLDUPXUPJQQ-UHFFFAOYSA-N CC(NCC(c(cc1)ccc1[N+]([O-])=O)O)=O Chemical compound CC(NCC(c(cc1)ccc1[N+]([O-])=O)O)=O HYBXLDUPXUPJQQ-UHFFFAOYSA-N 0.000 description 1
- PXUCWKJFRBNHKS-UHFFFAOYSA-N NC(c1c(N)[nH]cc1-c(cc1)ccc1[N+]([O-])=O)=O Chemical compound NC(c1c(N)[nH]cc1-c(cc1)ccc1[N+]([O-])=O)=O PXUCWKJFRBNHKS-UHFFFAOYSA-N 0.000 description 1
- QGMHMZOHCYYHBA-UHFFFAOYSA-N NCC(c(cc1)ccc1[N+]([O-])=O)=O Chemical compound NCC(c(cc1)ccc1[N+]([O-])=O)=O QGMHMZOHCYYHBA-UHFFFAOYSA-N 0.000 description 1
- YZLPITQVHNCXRU-UHFFFAOYSA-N Nc([nH]cc1-c(cc2)ccc2[N+]([O-])=O)c1C#N Chemical compound Nc([nH]cc1-c(cc2)ccc2[N+]([O-])=O)c1C#N YZLPITQVHNCXRU-UHFFFAOYSA-N 0.000 description 1
- NAIKHCBDZGSGHH-UHFFFAOYSA-N O=C=Nc(cc(C(F)(F)F)cc1)c1F Chemical compound O=C=Nc(cc(C(F)(F)F)cc1)c1F NAIKHCBDZGSGHH-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0501354A FR2881742B1 (fr) | 2005-02-10 | 2005-02-10 | Pyrroles substitues, compositions les contenant, procede de fabrication et utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1851198E true PT1851198E (pt) | 2009-03-26 |
Family
ID=35478244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT06709274T PT1851198E (pt) | 2005-02-10 | 2006-02-08 | Pirroles substituídos, composições contendo-os, processo de fabrico e utilização |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US7592365B2 (pt) |
| EP (1) | EP1851198B1 (pt) |
| JP (1) | JP2008530061A (pt) |
| KR (1) | KR20070101317A (pt) |
| CN (1) | CN101115716A (pt) |
| AR (1) | AR052571A1 (pt) |
| AT (1) | ATE419234T1 (pt) |
| AU (1) | AU2006212106A1 (pt) |
| BR (1) | BRPI0606955A2 (pt) |
| CA (1) | CA2596822A1 (pt) |
| CR (1) | CR9231A (pt) |
| CY (1) | CY1108916T1 (pt) |
| DE (1) | DE602006004566D1 (pt) |
| DK (1) | DK1851198T3 (pt) |
| DO (1) | DOP2006000028A (pt) |
| EA (1) | EA013060B1 (pt) |
| ES (1) | ES2319926T3 (pt) |
| FR (1) | FR2881742B1 (pt) |
| GT (1) | GT200600048A (pt) |
| HR (1) | HRP20090158T1 (pt) |
| IL (1) | IL184488A0 (pt) |
| MA (1) | MA29248B1 (pt) |
| MX (1) | MX2007008789A (pt) |
| MY (1) | MY142082A (pt) |
| NO (1) | NO20074528L (pt) |
| PA (1) | PA8661601A1 (pt) |
| PE (1) | PE20061086A1 (pt) |
| PL (1) | PL1851198T3 (pt) |
| PT (1) | PT1851198E (pt) |
| RS (1) | RS50806B (pt) |
| SI (1) | SI1851198T1 (pt) |
| TN (1) | TNSN07241A1 (pt) |
| TW (1) | TW200640858A (pt) |
| UY (1) | UY29371A1 (pt) |
| WO (1) | WO2006084996A1 (pt) |
| ZA (1) | ZA200706157B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2881426B1 (fr) | 2005-02-03 | 2007-03-30 | Aventis Pharma Sa | Pyrolles et imidazoles substitues, compositions les contenant, procede de frabrication et utilisation |
| PL2084130T3 (pl) * | 2006-10-23 | 2012-11-30 | Lexicon Pharmaceuticals Inc | Sposób wytwarzania 5-alkilo-7H-pirolo[2,3-d]pirymidyn-2-oli |
| TW201111385A (en) | 2009-08-27 | 2011-04-01 | Biocryst Pharm Inc | Heterocyclic compounds as janus kinase inhibitors |
| US20120244141A1 (en) | 2010-09-28 | 2012-09-27 | Boehringer Ingelheim International Gmbh | Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors |
| WO2020034988A1 (zh) * | 2018-08-14 | 2020-02-20 | 江苏豪森药业集团有限公司 | 凋亡信号调节激酶1抑制剂的盐及其晶型 |
| CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0107901D0 (en) * | 2001-03-29 | 2001-05-23 | Cyclacel Ltd | Anti-cancer compounds |
| JP2005504806A (ja) * | 2001-09-21 | 2005-02-17 | スミスクライン・ビーチャム・コーポレイション | 化合物 |
| US7307097B2 (en) | 2001-09-27 | 2007-12-11 | Smithkline Beechman Corporation | Chemical compounds |
| US20040138269A1 (en) * | 2002-10-11 | 2004-07-15 | Sugen, Inc. | Substituted pyrroles as kinase inhibitors |
| GB0229581D0 (en) * | 2002-12-19 | 2003-01-22 | Cyclacel Ltd | Use |
| EP1606284B1 (en) * | 2003-03-13 | 2009-12-02 | Vertex Pharmaceuticals Incorporated | Compositions useful as protein kinase inhibitors |
| DE10354060A1 (de) * | 2003-11-19 | 2005-06-02 | Merck Patent Gmbh | Pyrrolderivate |
| US7183285B2 (en) * | 2004-04-29 | 2007-02-27 | Pharmix Corp. | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
| FR2881426B1 (fr) | 2005-02-03 | 2007-03-30 | Aventis Pharma Sa | Pyrolles et imidazoles substitues, compositions les contenant, procede de frabrication et utilisation |
-
2005
- 2005-02-10 FR FR0501354A patent/FR2881742B1/fr not_active Expired - Fee Related
-
2006
- 2006-02-02 DO DO2006000028A patent/DOP2006000028A/es unknown
- 2006-02-02 PA PA20068661601A patent/PA8661601A1/es unknown
- 2006-02-02 PE PE2006000135A patent/PE20061086A1/es not_active Application Discontinuation
- 2006-02-03 MY MYPI20060441A patent/MY142082A/en unknown
- 2006-02-08 KR KR1020077018321A patent/KR20070101317A/ko not_active Application Discontinuation
- 2006-02-08 SI SI200630232T patent/SI1851198T1/sl unknown
- 2006-02-08 DK DK06709274T patent/DK1851198T3/da active
- 2006-02-08 ES ES06709274T patent/ES2319926T3/es active Active
- 2006-02-08 AR ARP060100452A patent/AR052571A1/es unknown
- 2006-02-08 JP JP2007554598A patent/JP2008530061A/ja active Pending
- 2006-02-08 CN CNA2006800044573A patent/CN101115716A/zh active Pending
- 2006-02-08 PL PL06709274T patent/PL1851198T3/pl unknown
- 2006-02-08 CA CA002596822A patent/CA2596822A1/fr not_active Abandoned
- 2006-02-08 EA EA200701688A patent/EA013060B1/ru not_active IP Right Cessation
- 2006-02-08 WO PCT/FR2006/000286 patent/WO2006084996A1/fr active Application Filing
- 2006-02-08 DE DE602006004566T patent/DE602006004566D1/de active Active
- 2006-02-08 GT GT200600048A patent/GT200600048A/es unknown
- 2006-02-08 RS RSP-2009/0128A patent/RS50806B/sr unknown
- 2006-02-08 AT AT06709274T patent/ATE419234T1/de active
- 2006-02-08 ZA ZA200706157A patent/ZA200706157B/xx unknown
- 2006-02-08 MX MX2007008789A patent/MX2007008789A/es active IP Right Grant
- 2006-02-08 AU AU2006212106A patent/AU2006212106A1/en not_active Withdrawn
- 2006-02-08 EP EP06709274A patent/EP1851198B1/fr active Active
- 2006-02-08 BR BRPI0606955-0A patent/BRPI0606955A2/pt not_active IP Right Cessation
- 2006-02-08 PT PT06709274T patent/PT1851198E/pt unknown
- 2006-02-09 TW TW095104288A patent/TW200640858A/zh unknown
- 2006-02-10 UY UY29371A patent/UY29371A1/es unknown
-
2007
- 2007-06-26 TN TNP2007000241A patent/TNSN07241A1/fr unknown
- 2007-07-06 CR CR9231A patent/CR9231A/es not_active Application Discontinuation
- 2007-07-08 IL IL184488A patent/IL184488A0/en unknown
- 2007-08-01 US US11/832,208 patent/US7592365B2/en not_active Expired - Fee Related
- 2007-08-13 MA MA30134A patent/MA29248B1/fr unknown
- 2007-09-06 NO NO20074528A patent/NO20074528L/no not_active Application Discontinuation
-
2009
- 2009-03-17 HR HR20090158T patent/HRP20090158T1/xx unknown
- 2009-03-23 CY CY20091100344T patent/CY1108916T1/el unknown
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