PT1835923E - Regimes para viscossuplementação intra-articular - Google Patents

Regimes para viscossuplementação intra-articular Download PDF

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Publication number
PT1835923E
PT1835923E PT58550344T PT05855034T PT1835923E PT 1835923 E PT1835923 E PT 1835923E PT 58550344 T PT58550344 T PT 58550344T PT 05855034 T PT05855034 T PT 05855034T PT 1835923 E PT1835923 E PT 1835923E
Authority
PT
Portugal
Prior art keywords
quot
pain
gel
viscossupplement
use according
Prior art date
Application number
PT58550344T
Other languages
English (en)
Portuguese (pt)
Inventor
Francois Bailleul
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36633154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1835923(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of PT1835923E publication Critical patent/PT1835923E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
PT58550344T 2004-12-30 2005-12-20 Regimes para viscossuplementação intra-articular PT1835923E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64074904P 2004-12-30 2004-12-30

Publications (1)

Publication Number Publication Date
PT1835923E true PT1835923E (pt) 2013-11-04

Family

ID=36633154

Family Applications (2)

Application Number Title Priority Date Filing Date
PT58550344T PT1835923E (pt) 2004-12-30 2005-12-20 Regimes para viscossuplementação intra-articular
PT131804650T PT2664334E (pt) 2004-12-30 2005-12-20 Regimes para viscossuplementação intra-articular

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT131804650T PT2664334E (pt) 2004-12-30 2005-12-20 Regimes para viscossuplementação intra-articular

Country Status (16)

Country Link
US (4) US7931030B2 (enExample)
EP (5) EP2664335A3 (enExample)
JP (4) JP5725594B2 (enExample)
KR (3) KR101808800B1 (enExample)
CN (4) CN102416020A (enExample)
AU (1) AU2005323095B2 (enExample)
BR (1) BRPI0518542A2 (enExample)
CA (2) CA2590159C (enExample)
DK (2) DK2664334T3 (enExample)
ES (2) ES2537751T3 (enExample)
HU (1) HUE025255T2 (enExample)
IL (1) IL183581A (enExample)
PL (2) PL2664334T3 (enExample)
PT (2) PT1835923E (enExample)
SI (2) SI2664334T1 (enExample)
WO (1) WO2006073835A2 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2891651B2 (ja) 1995-07-03 1999-05-17 三菱重工業株式会社 C型コイル
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
ES2537751T3 (es) 2004-12-30 2015-06-11 Genzyme Corporation Regímenes para viscosuplementación intraarticular
EP3028677A1 (en) 2005-12-14 2016-06-08 Anika Therapeutics Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid
WO2007070546A2 (en) * 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Meniscal implant of hyaluronic acid derivatives for treatment of meniscal defects
EP1968614A2 (en) * 2005-12-14 2008-09-17 Anika Therapeutics Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid
AU2007328871B2 (en) * 2006-12-06 2013-11-21 Seikagaku Corporation Pharmaceutical agent having long-lasting effect of treating arthritic disorders
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
AU2009288118B2 (en) 2008-09-02 2014-12-11 Allergan, Inc. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
EP2451381B1 (en) * 2009-07-10 2016-04-06 Kirk Promotion LTD. Implantable medical device for lubrication of a synovial joint
JO3008B1 (ar) 2009-08-13 2016-09-05 Seikagaku Kogyo Co Ltd تركيب صيدلي لتخفيف الألم
KR101834588B1 (ko) 2010-08-23 2018-03-05 덴카 주식회사 가교 히알루론산 조성물 및 자기 가교 히알루론산 입자
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
US9492474B2 (en) 2013-07-10 2016-11-15 Matrix Biology Institute Compositions of hyaluronan with high elasticity and uses thereof
KR101582380B1 (ko) * 2013-09-11 2016-01-05 주식회사 제네웰 손상 조직에 대한 세포 전달 및 조직 재생용 생체재료와 제조방법
WO2015142781A1 (en) * 2014-03-21 2015-09-24 Rmg, Inc. Mobile based exercise and rehabilitation
GB201408752D0 (en) * 2014-05-16 2014-07-02 Stemmatters Biotecnologia E Medicina Regenerativa Sa Arthritis treatment
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
US10004824B2 (en) 2015-05-11 2018-06-26 Laboratoires Vivacy Compositions comprising at least one polyol and at least one anesthetic
WO2016034745A2 (en) * 2015-09-22 2016-03-10 Cylenchar Limited A method for concentrating and/or entrapping radioisotopes from an aqueous solution
PT3842047T (pt) 2015-09-24 2024-09-19 Matrix Biology Inst Composições de hialuronano de elevada elasticidade e processos para o seu uso
KR20170090965A (ko) * 2016-01-29 2017-08-08 한미약품 주식회사 복합 히알루론산 가교물 및 그 제조방법
ES2953017T3 (es) * 2018-04-03 2023-11-07 Sanofi Sa Dispositivo de tira de inmunoensayo de flujo lateral
WO2022051060A1 (en) * 2020-09-01 2022-03-10 Orthogenrx, Inc. Crosslinking of non-animal-derived hyaluronic acid with divinyl sulfone
WO2025068242A1 (en) * 2023-09-25 2025-04-03 Hyamedix Dexamethasone delivery system

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716224A (en) 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
US4636524A (en) * 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US5128326A (en) * 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US5099013A (en) 1985-03-12 1992-03-24 Biomatrix, Inc, Hylan preparation and method of recovery thereof from animal tissues
US4713448A (en) 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
SE8501723L (sv) * 1985-04-09 1986-10-10 Pharmacia Ab Preparation att anvendas vid behandling av ledinflammation
US4808576A (en) * 1986-04-28 1989-02-28 Mobay Corporation Remote administration of hyaluronic acid to mammals
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
US4795741A (en) * 1987-05-06 1989-01-03 Biomatrix, Inc. Compositions for therapeutic percutaneous embolization and the use thereof
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5246698A (en) 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
CA2061566C (en) * 1992-02-20 2002-07-09 Rudolf E. Falk Treatment of disease employing hyaluronic acid and nsaids
US5219360A (en) * 1991-05-10 1993-06-15 Fortis Research Corporation Mammary prosthesis fill and method of making same
US5143351A (en) * 1991-08-29 1992-09-01 Pierce Daniel H Self-locking valve spring retainer
US5690961A (en) * 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
US5612321A (en) * 1995-06-22 1997-03-18 Hercules Incorporated Antioxidant grafted polysaccharides
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
AU722250B2 (en) 1995-11-15 2000-07-27 Seikagaku Corporation Photocured crosslinked-hyaluronic acid gel and method of preparation thereof
US6096728A (en) 1996-02-09 2000-08-01 Amgen Inc. Composition and method for treating inflammatory diseases
DE69739656D1 (de) * 1996-02-09 2009-12-31 Amgen Inc 1 inhibitor und hyaluronan als polymer mit verzögerter wirkstofffreigabe
JP3521378B2 (ja) * 1996-08-13 2004-04-19 コニカミノルタホールディングス株式会社 両面複写装置
US6294170B1 (en) * 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
ATE261454T1 (de) * 1998-02-27 2004-03-15 Stichting Hippomedics Verfahren zur herstellung von vernetzter hyaluronsäure
US6630457B1 (en) * 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
CA2349168C (en) 1998-11-10 2009-01-06 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel, method of its production and medical material containing it
US6677321B1 (en) * 1999-12-09 2004-01-13 Bruce Levin Methods and compositions for treatment of inflammatory disease
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US6645485B2 (en) * 2000-05-10 2003-11-11 Allan R. Dunn Method of treating inflammation in the joints of a body
US6800298B1 (en) * 2000-05-11 2004-10-05 Clemson University Biological lubricant composition and method of applying lubricant composition
US6527760B1 (en) * 2000-09-25 2003-03-04 Vijay B. Vad Out-patient joint lavage kit and protocol
EP1217008B1 (en) 2000-12-19 2006-03-01 Seikagaku Corporation Photocurable hyaluronic acid derivative and process for producing the same, and photocured crosslinked hyaluronic acid derivative and medical material using the same
US7119062B1 (en) * 2001-02-23 2006-10-10 Neucoll, Inc. Methods and compositions for improved articular surgery using collagen
US20030008817A1 (en) * 2001-07-03 2003-01-09 Tom Sander Cross-link reversing agent
MXPA01011542A (es) * 2001-11-13 2003-05-22 Alcon Inc Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel.
AU2003248584A1 (en) * 2002-03-01 2003-09-16 Warner-Lambert Company Llc Method of treating osteoarthritis
US20030232784A1 (en) * 2002-06-14 2003-12-18 Benedict James J. Hyaluronic acid-associated superoxide dismutase mimics and their use in the treatment of joint pain
JP4383035B2 (ja) * 2002-10-29 2009-12-16 電気化学工業株式会社 ヒアルロン酸ゲル及びその製造方法
CA2517145C (en) * 2003-03-05 2017-08-01 Halozyme, Inc. Soluble hyaluronidase glycoprotein (shasegp), process for preparing the same, uses and pharmaceutical compositions comprising thereof
US20050026887A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a steroid
JP2007507431A (ja) * 2003-10-09 2007-03-29 ロバート・ジョン・ペトレラ ヒアルロン酸を使用する急性及び過用性の捻挫及び筋違いの治療方法
US8524213B2 (en) 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
MXPA06007556A (es) 2003-12-30 2006-08-31 Genzyme Corp Geles cohesivos de hialuronano y/o hilano entrecruzados, su preparacion y su uso.
JP2008507553A (ja) * 2004-07-23 2008-03-13 ミューコサル セラピューティクス リミテッド ライアビリディ カンパニー 粘性補給のための組成物および方法
AU2005272578A1 (en) * 2004-08-13 2006-02-23 Angiotech International Ag Compositions and methods using hyaluronic acid and hyluronidase inhibitors
ES2537751T3 (es) 2004-12-30 2015-06-11 Genzyme Corporation Regímenes para viscosuplementación intraarticular
EP1968614A2 (en) 2005-12-14 2008-09-17 Anika Therapeutics Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid

Also Published As

Publication number Publication date
AU2005323095B2 (en) 2011-12-15
EP2664334B1 (en) 2015-03-04
EP2664334A1 (en) 2013-11-20
US7931030B2 (en) 2011-04-26
CN103860582A (zh) 2014-06-18
KR20070104579A (ko) 2007-10-26
HUE025255T2 (en) 2016-03-29
EP2289523A3 (en) 2011-09-28
ES2436179T3 (es) 2013-12-27
EP2664335A3 (en) 2015-12-16
EP2664336A2 (en) 2013-11-20
PL1835923T3 (pl) 2014-03-31
PT2664334E (pt) 2015-04-23
CN101094680A (zh) 2007-12-26
ES2537751T3 (es) 2015-06-11
EP1835923A2 (en) 2007-09-26
WO2006073835A2 (en) 2006-07-13
KR101808800B1 (ko) 2018-01-18
SI2664334T1 (sl) 2015-06-30
JP2008526747A (ja) 2008-07-24
EP1835923B1 (en) 2013-10-09
IL183581A (en) 2016-10-31
US20130197444A1 (en) 2013-08-01
WO2006073835A3 (en) 2006-10-05
SI1835923T1 (sl) 2014-01-31
DK2664334T3 (en) 2015-03-23
CA2744999A1 (en) 2006-07-13
KR20150052326A (ko) 2015-05-13
CN104689460A (zh) 2015-06-10
JP6139716B2 (ja) 2017-05-31
AU2005323095A1 (en) 2006-07-13
PL2664334T3 (pl) 2015-08-31
JP2016128469A (ja) 2016-07-14
CN102416020A (zh) 2012-04-18
US20120258931A1 (en) 2012-10-11
EP2664335A2 (en) 2013-11-20
DK1835923T3 (da) 2013-10-21
US20060148755A1 (en) 2006-07-06
EP2289523A2 (en) 2011-03-02
BRPI0518542A2 (pt) 2008-11-25
JP2013035860A (ja) 2013-02-21
JP2015007077A (ja) 2015-01-15
CA2590159A1 (en) 2006-07-13
EP2664336A3 (en) 2015-12-16
CN104689460B (zh) 2018-03-13
US20110183936A1 (en) 2011-07-28
CA2590159C (en) 2011-07-12
KR20140041926A (ko) 2014-04-04
JP5725594B2 (ja) 2015-05-27
IL183581A0 (en) 2007-10-31

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