PT1809270E - Ácido 5,6,7-tri-hidroxi-heptanóico e os seus análogos para o tratamento de doenças oculares e doenças associadas com respostas hiperproliferativas e angiogénicas - Google Patents

Ácido 5,6,7-tri-hidroxi-heptanóico e os seus análogos para o tratamento de doenças oculares e doenças associadas com respostas hiperproliferativas e angiogénicas Download PDF

Info

Publication number
PT1809270E
PT1809270E PT05824279T PT05824279T PT1809270E PT 1809270 E PT1809270 E PT 1809270E PT 05824279 T PT05824279 T PT 05824279T PT 05824279 T PT05824279 T PT 05824279T PT 1809270 E PT1809270 E PT 1809270E
Authority
PT
Portugal
Prior art keywords
straight
branched chain
composition according
compound
formula
Prior art date
Application number
PT05824279T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of PT1809270E publication Critical patent/PT1809270E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PT05824279T 2004-11-09 2005-11-08 Ácido 5,6,7-tri-hidroxi-heptanóico e os seus análogos para o tratamento de doenças oculares e doenças associadas com respostas hiperproliferativas e angiogénicas PT1809270E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62620904P 2004-11-09 2004-11-09

Publications (1)

Publication Number Publication Date
PT1809270E true PT1809270E (pt) 2010-05-25

Family

ID=35809550

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05824279T PT1809270E (pt) 2004-11-09 2005-11-08 Ácido 5,6,7-tri-hidroxi-heptanóico e os seus análogos para o tratamento de doenças oculares e doenças associadas com respostas hiperproliferativas e angiogénicas

Country Status (19)

Country Link
US (2) US7879905B2 (https=)
EP (1) EP1809270B1 (https=)
JP (3) JP2008519763A (https=)
KR (1) KR101237534B1 (https=)
CN (1) CN101052387A (https=)
AT (1) ATE461696T1 (https=)
AU (1) AU2005304733B2 (https=)
BR (1) BRPI0517972A (https=)
CA (1) CA2584286C (https=)
CY (1) CY1110644T1 (https=)
DE (1) DE602005020178D1 (https=)
DK (1) DK1809270T3 (https=)
ES (1) ES2340786T3 (https=)
MX (1) MX2007004622A (https=)
PL (1) PL1809270T3 (https=)
PT (1) PT1809270E (https=)
SI (1) SI1809270T1 (https=)
WO (1) WO2006052950A1 (https=)
ZA (1) ZA200703992B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1809270T3 (pl) * 2004-11-09 2010-08-31 Alcon Inc Kwas 5,6,7-trihydroksyheptanowy i jego analogi do leczenia chorób oczu i chorób związanych z odpowiedziami hiperproliferacyjnymi i angiogenicznymi
US20060154981A1 (en) * 2005-01-12 2006-07-13 Alcon, Inc. Method of reducing intraocular pressure and treating glaucoma
US7687539B1 (en) 2005-11-07 2010-03-30 Alcon Research, Ltd. Method of treating ocular allergy
MX2009004962A (es) * 2006-11-07 2009-05-21 Alcon Res Ltd Metodo para tratar asma, rinitis alergia y trastornos de la piel.
CA2781309A1 (en) * 2009-12-04 2011-06-09 Euclid Systems Corporation Composition and methods for the prevention and treatment of macular degeneration, diabetic retinopathy, and diabetic macular edema
WO2011096941A1 (en) * 2010-02-08 2011-08-11 Alcon Research, Ltd. Method of treating ocular allergy
WO2011106599A1 (en) * 2010-02-25 2011-09-01 Alcon Research, Ltd. Method of accelerating corneal wound healing
US11491006B2 (en) 2019-04-10 2022-11-08 Neovasc Tiara Inc. Prosthetic valve with natural blood flow

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4975537A (en) 1985-10-23 1990-12-04 The Upjohn Company Δ9(11) -angiostatic steroids
US4771042A (en) 1985-11-25 1988-09-13 The Upjohn Company Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments
JP2834512B2 (ja) * 1990-01-30 1998-12-09 帝人株式会社 リポキシン誘導体を有効成分とする疾患治療剤
US5441951A (en) 1994-06-15 1995-08-15 Brigham & Women's Hospital Lipoxin compounds
US6048897A (en) * 1993-06-15 2000-04-11 Brigham And Women's Hospital Lipoxin compounds and their use in treating cell proliferative disorders
JPH08268886A (ja) 1995-03-31 1996-10-15 Eisai Co Ltd 血管新生抑制剤
ATE258791T1 (de) * 1999-11-09 2004-02-15 Alcon Inc Lipoxin-a4 und deren analoge zur behandlung von trockenen augen
AR030345A1 (es) 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
WO2002070068A2 (en) * 2001-03-02 2002-09-12 The Brigham And Women's Hospital Lipoxin analogs as novel inhibitors of angiogenesis
DE602005017762D1 (de) 2004-05-14 2009-12-31 Alcon Inc Methode zur behandlung trockener augen und uveitis
PL1809270T3 (pl) * 2004-11-09 2010-08-31 Alcon Inc Kwas 5,6,7-trihydroksyheptanowy i jego analogi do leczenia chorób oczu i chorób związanych z odpowiedziami hiperproliferacyjnymi i angiogenicznymi

Also Published As

Publication number Publication date
US20060099248A1 (en) 2006-05-11
ES2340786T3 (es) 2010-06-09
EP1809270B1 (en) 2010-03-24
KR101237534B1 (ko) 2013-03-04
ZA200703992B (en) 2009-08-26
AU2005304733A1 (en) 2006-05-18
EP1809270A1 (en) 2007-07-25
SI1809270T1 (sl) 2010-07-30
PL1809270T3 (pl) 2010-08-31
US7879905B2 (en) 2011-02-01
DK1809270T3 (da) 2010-06-14
CN101052387A (zh) 2007-10-10
MX2007004622A (es) 2007-06-11
CA2584286C (en) 2014-01-14
US20110082200A1 (en) 2011-04-07
AU2005304733B2 (en) 2011-04-07
JP2012107073A (ja) 2012-06-07
ATE461696T1 (de) 2010-04-15
CA2584286A1 (en) 2006-05-18
HK1110768A1 (en) 2008-07-25
BRPI0517972A (pt) 2008-10-21
WO2006052950A1 (en) 2006-05-18
DE602005020178D1 (de) 2010-05-06
KR20070083980A (ko) 2007-08-24
JP2014198730A (ja) 2014-10-23
CY1110644T1 (el) 2015-04-29
JP2008519763A (ja) 2008-06-12

Similar Documents

Publication Publication Date Title
US20100048608A1 (en) Histone Deacetylase Inhibitors for the Treatment of Ocular Neovascular or Edematous Disorders and Diseases
CN101888839B (zh) 治疗眼睛病症的omega-3脂肪酸、羟基多不饱和脂肪酸、脂氧素类化合物或脂氧化物类化合物
US20110082200A1 (en) 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses
JP2004518612A (ja) インドール誘導体を用いて眼圧を下降させる方法
JP7636742B2 (ja) 制御送達性クロマカリムプロドラッグ
JP5586117B2 (ja) ベンゾイルフェニル酢酸を使用して、血管形成関連障害を処置するための方法
JP2002506022A (ja) 新脈管形成の阻害
US20050143468A1 (en) Method of treating vascular endothelial growth factor mediated vascular disorders
HK1110768B (en) 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses
WO2009110526A1 (ja) 3’,5-ジ-2-プロペニル-(1,1’-ビフェニル)-2,4’-ジオールを有効成分として含有する視神経障害の予防又は治療剤
NZ748526A (en) Novel prostaglandin derivative
JP2004182701A (ja) ヒドロキサム酸誘導体を有効成分とする眼組織血管新生阻害剤