PT1452171E - Suspensões líquidas farmacêuticas - Google Patents
Suspensões líquidas farmacêuticas Download PDFInfo
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- PT1452171E PT1452171E PT04013422T PT04013422T PT1452171E PT 1452171 E PT1452171 E PT 1452171E PT 04013422 T PT04013422 T PT 04013422T PT 04013422 T PT04013422 T PT 04013422T PT 1452171 E PT1452171 E PT 1452171E
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- 238000007254 oxidation reaction Methods 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 229960004624 perflexane Drugs 0.000 description 1
- WTWWXOGTJWMJHI-UHFFFAOYSA-N perflubron Chemical compound FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br WTWWXOGTJWMJHI-UHFFFAOYSA-N 0.000 description 1
- 229960001217 perflubron Drugs 0.000 description 1
- ZJIJAJXFLBMLCK-UHFFFAOYSA-N perfluorohexane Chemical compound FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F ZJIJAJXFLBMLCK-UHFFFAOYSA-N 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000007971 pharmaceutical suspension Substances 0.000 description 1
- 239000002831 pharmacologic agent Substances 0.000 description 1
- 238000001782 photodegradation Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 235000011151 potassium sulphates Nutrition 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011027 product recovery Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- ZMRUPTIKESYGQW-UHFFFAOYSA-N propranolol hydrochloride Chemical compound [H+].[Cl-].C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 ZMRUPTIKESYGQW-UHFFFAOYSA-N 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000007844 respiratory distress syndrome in premature infants Diseases 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229940126586 small molecule drug Drugs 0.000 description 1
- 235000015424 sodium Nutrition 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 238000007614 solvation Methods 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- PXXNTAGJWPJAGM-UHFFFAOYSA-N vertaline Natural products C1C2C=3C=C(OC)C(OC)=CC=3OC(C=C3)=CC=C3CCC(=O)OC1CC1N2CCCC1 PXXNTAGJWPJAGM-UHFFFAOYSA-N 0.000 description 1
- 238000004017 vitrification Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
- 235000005074 zinc chloride Nutrition 0.000 description 1
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/028244 WO2002032402A1 (en) | 2000-10-13 | 2000-10-13 | Composition and method for stable injectable liquids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1452171E true PT1452171E (pt) | 2010-03-08 |
Family
ID=21741883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT04013422T PT1452171E (pt) | 2000-10-13 | 2000-10-13 | Suspensões líquidas farmacêuticas |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1328255A1 (OSRAM) |
| JP (1) | JP2004513093A (OSRAM) |
| KR (1) | KR20030096224A (OSRAM) |
| CN (1) | CN100339066C (OSRAM) |
| AU (2) | AU1198601A (OSRAM) |
| CA (2) | CA2689856C (OSRAM) |
| ES (1) | ES2337252T3 (OSRAM) |
| MX (1) | MXPA03003236A (OSRAM) |
| NO (1) | NO20031706L (OSRAM) |
| PL (1) | PL360052A1 (OSRAM) |
| PT (1) | PT1452171E (OSRAM) |
| WO (1) | WO2002032402A1 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050267222A1 (en) * | 2002-10-22 | 2005-12-01 | Dainippon Pharmaceutical Co. Ltd. | Stabilized composition |
| JP2007001865A (ja) * | 2003-09-16 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 脂溶性薬物封入微粒子、その製造法およびそれを含有する製剤 |
| GB0408199D0 (en) * | 2004-04-13 | 2004-05-19 | Cambridge Biostability Ltd | Liquids containing suspended sugar glass particles |
| AU2005232441B2 (en) | 2004-04-13 | 2010-11-11 | Cambridge Biostability Limited | Liquids containing suspended glass particles |
| GB2430880A (en) * | 2005-10-04 | 2007-04-11 | Cambridge Biostability Ltd | Pharmaceutical compositions stabilized in glassy particles |
| GB0523638D0 (en) | 2005-11-21 | 2005-12-28 | Cambridge Biostability Ltd | Pharmaceutical device for the administration of substances to patients |
| US8946200B2 (en) | 2006-11-02 | 2015-02-03 | Southwest Research Institute | Pharmaceutically active nanosuspensions |
| MX2010007632A (es) * | 2008-01-18 | 2010-08-03 | Asahi Kasei Pharma Corp | Composicion farmaceutica estable. |
| US8404850B2 (en) | 2008-03-13 | 2013-03-26 | Southwest Research Institute | Bis-quaternary pyridinium-aldoxime salts and treatment of exposure to cholinesterase inhibitors |
| US8722706B2 (en) | 2008-08-15 | 2014-05-13 | Southwest Research Institute | Two phase bioactive formulations of bis-quaternary pyridinium oxime sulfonate salts |
| US8309134B2 (en) | 2008-10-03 | 2012-11-13 | Southwest Research Institute | Modified calcium phosphate nanoparticle formation |
| WO2010146536A1 (en) | 2009-06-18 | 2010-12-23 | Koninklijke Philips Electronics N.V. | Suspension of particles with drug |
| WO2011007327A2 (en) | 2009-07-16 | 2011-01-20 | Koninklijke Philips Electronics N.V. | Suspension for therapeutic use and device for delivering said suspension |
| ES2362525B8 (es) | 2009-10-08 | 2013-01-03 | Azurebio, S.L. | Formulación de medicamentos en forma de agujas percutaneas penetrantes. |
| US9028873B2 (en) | 2010-02-08 | 2015-05-12 | Southwest Research Institute | Nanoparticles for drug delivery to the central nervous system |
| TWI654098B (zh) | 2014-03-24 | 2019-03-21 | 日商精工愛普生股份有限公司 | Belt printing device and tape printing system |
| WO2015145353A1 (en) * | 2014-03-27 | 2015-10-01 | Novartis Ag | Spray-dried solid-in-oil-in-water dispersions for inhalation of active pharmaceutical ingredients |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR78151B (OSRAM) * | 1982-04-05 | 1984-09-26 | Alcon Lab Inc | |
| US5518731A (en) * | 1990-09-27 | 1996-05-21 | Allergan, Inc. | Nonaqueous fluorinated drug delivery vehicle suspensions |
| WO1993018748A1 (en) * | 1992-03-19 | 1993-09-30 | Allergan, Inc. | Compositions comprising a drug delivery vehicle suspended in a nonaqueous fluorinated liquid |
| GB9705588D0 (en) * | 1997-03-18 | 1997-05-07 | Anglia Research Foundation | Stable particle in liquid formulations |
| US6190701B1 (en) * | 1999-03-17 | 2001-02-20 | Peter M. Ronai | Composition and method for stable injectable liquids |
-
2000
- 2000-10-13 PL PL00360052A patent/PL360052A1/xx unknown
- 2000-10-13 AU AU1198601A patent/AU1198601A/xx active Pending
- 2000-10-13 CN CNB008199655A patent/CN100339066C/zh not_active Expired - Fee Related
- 2000-10-13 WO PCT/US2000/028244 patent/WO2002032402A1/en not_active Ceased
- 2000-10-13 JP JP2002535640A patent/JP2004513093A/ja not_active Withdrawn
- 2000-10-13 ES ES04013422T patent/ES2337252T3/es not_active Expired - Lifetime
- 2000-10-13 EP EP00973483A patent/EP1328255A1/en not_active Withdrawn
- 2000-10-13 CA CA2689856A patent/CA2689856C/en not_active Expired - Lifetime
- 2000-10-13 AU AU2001211986A patent/AU2001211986B2/en not_active Ceased
- 2000-10-13 MX MXPA03003236A patent/MXPA03003236A/es active IP Right Grant
- 2000-10-13 PT PT04013422T patent/PT1452171E/pt unknown
- 2000-10-13 KR KR10-2003-7004941A patent/KR20030096224A/ko not_active Ceased
- 2000-10-13 CA CA2424656A patent/CA2424656C/en not_active Expired - Lifetime
-
2003
- 2003-04-11 NO NO20031706A patent/NO20031706L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004513093A (ja) | 2004-04-30 |
| AU2001211986B2 (en) | 2007-04-26 |
| CA2689856C (en) | 2013-09-24 |
| EP1328255A1 (en) | 2003-07-23 |
| CN1527699A (zh) | 2004-09-08 |
| KR20030096224A (ko) | 2003-12-24 |
| MXPA03003236A (es) | 2004-12-03 |
| NO20031706D0 (no) | 2003-04-11 |
| WO2002032402A1 (en) | 2002-04-25 |
| PL360052A1 (en) | 2004-09-06 |
| CA2424656C (en) | 2010-03-23 |
| ES2337252T3 (es) | 2010-04-22 |
| CA2689856A1 (en) | 2002-04-25 |
| NO20031706L (no) | 2003-04-11 |
| CA2424656A1 (en) | 2002-04-25 |
| AU1198601A (en) | 2002-04-29 |
| CN100339066C (zh) | 2007-09-26 |
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