PT1432709E - Indolizinas de 1-glioxilamida para o trtamento do cancro - Google Patents
Indolizinas de 1-glioxilamida para o trtamento do cancroInfo
- Publication number
- PT1432709E PT1432709E PT02798231T PT02798231T PT1432709E PT 1432709 E PT1432709 E PT 1432709E PT 02798231 T PT02798231 T PT 02798231T PT 02798231 T PT02798231 T PT 02798231T PT 1432709 E PT1432709 E PT 1432709E
- Authority
- PT
- Portugal
- Prior art keywords
- substituted
- group
- unsubstituted
- independently
- aryl group
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 150000002478 indolizines Chemical class 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 5
- 125000001931 aliphatic group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32202001P | 2001-09-13 | 2001-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1432709E true PT1432709E (pt) | 2005-10-31 |
Family
ID=23253054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT02798231T PT1432709E (pt) | 2001-09-13 | 2002-09-13 | Indolizinas de 1-glioxilamida para o trtamento do cancro |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6861436B2 (enExample) |
| EP (1) | EP1432709B8 (enExample) |
| JP (1) | JP2005504795A (enExample) |
| KR (1) | KR20040053125A (enExample) |
| CN (1) | CN1568324A (enExample) |
| AT (1) | ATE300542T1 (enExample) |
| AU (1) | AU2002333626B2 (enExample) |
| BR (1) | BR0212794A (enExample) |
| CA (1) | CA2459886A1 (enExample) |
| DE (1) | DE60205265T2 (enExample) |
| ES (1) | ES2245747T3 (enExample) |
| IL (1) | IL160810A0 (enExample) |
| IS (1) | IS7176A (enExample) |
| MX (1) | MXPA04002323A (enExample) |
| NO (1) | NO20041035L (enExample) |
| NZ (1) | NZ531700A (enExample) |
| PT (1) | PT1432709E (enExample) |
| WO (1) | WO2003022846A1 (enExample) |
| ZA (1) | ZA200401996B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040116462A1 (en) * | 2002-12-12 | 2004-06-17 | Mitsunori Ono | Indolizine compounds |
| PT1432709E (pt) * | 2001-09-13 | 2005-10-31 | Synta Pharmaceuticals Corp | Indolizinas de 1-glioxilamida para o trtamento do cancro |
| JP2006504692A (ja) * | 2002-09-13 | 2006-02-09 | シンタ ファーマシューティカルズ コーポレーション | インドリジンの合成方法 |
| DE10318611A1 (de) | 2003-04-24 | 2004-11-11 | Elbion Ag | 4-, 6- oder 7-Hydroxyindole mit N-Oxidgruppen und deren Verwendung als Therapeutika |
| WO2005099824A1 (en) * | 2004-03-30 | 2005-10-27 | Synta Pharmaceuticals, Corp. | 1-glyoxylamide indolizines for treating lung and ovarian cancer |
| GB0413605D0 (en) | 2004-06-17 | 2004-07-21 | Addex Pharmaceuticals Sa | Novel compounds |
| US20070293456A9 (en) * | 2004-12-30 | 2007-12-20 | Anthony Hayford | Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds |
| WO2006128184A2 (en) * | 2005-05-20 | 2006-11-30 | Alantos-Pharmaceuticals, Inc. | Pyrimidine or triazine fused bicyclic metalloprotease inhibitors |
| US20070155738A1 (en) | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
| CA2733247C (en) * | 2008-08-14 | 2018-04-03 | Beta Pharma Canada Inc. | Heterocyclic amide derivatives as ep4 receptor antagonists |
| EP4008327A1 (en) | 2009-04-29 | 2022-06-08 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| AR077428A1 (es) * | 2009-07-29 | 2011-08-24 | Sanofi Aventis | (aza) indolizinacarboxamidas ciclicas su preparacion y su uso como agentes farmaceuticos |
| CN113603694B (zh) * | 2021-07-16 | 2022-07-22 | 浙江工业大学 | 一种1,2-二酮类化合物及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2287706A (en) * | 1994-03-21 | 1995-09-27 | Fujisawa Pharmaceutical Co | Indolizine derivatives |
| FR2757166B1 (fr) * | 1996-12-12 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derives du pyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent |
| WO1998047507A1 (en) * | 1997-04-24 | 1998-10-29 | Shionogi & Co., Ltd. | Method for the treatment of stroke using n-heterocyclic glyoxylamide compounds |
| US6472389B1 (en) | 1998-05-21 | 2002-10-29 | Shionogi & Co., Ltd. | Pyrrolo[1,2-b] pyridazine derivatives having sPLA2 inhibitory effect |
| CA2346334A1 (en) | 1998-10-14 | 2000-04-20 | Shionogi & Co., Ltd. | Composition for treating or preventing ischemia reperfusion injury |
| US6461538B2 (en) * | 1999-12-16 | 2002-10-08 | Fuji Photo Film Co., Ltd. | Production process for indolizine compounds and their use in organic light-emitting devices |
| PT1432709E (pt) * | 2001-09-13 | 2005-10-31 | Synta Pharmaceuticals Corp | Indolizinas de 1-glioxilamida para o trtamento do cancro |
| US20040116462A1 (en) * | 2002-12-12 | 2004-06-17 | Mitsunori Ono | Indolizine compounds |
-
2002
- 2002-09-13 PT PT02798231T patent/PT1432709E/pt unknown
- 2002-09-13 ES ES02798231T patent/ES2245747T3/es not_active Expired - Lifetime
- 2002-09-13 AU AU2002333626A patent/AU2002333626B2/en not_active Ceased
- 2002-09-13 US US10/244,088 patent/US6861436B2/en not_active Expired - Fee Related
- 2002-09-13 WO PCT/US2002/029154 patent/WO2003022846A1/en not_active Ceased
- 2002-09-13 DE DE60205265T patent/DE60205265T2/de not_active Expired - Fee Related
- 2002-09-13 CN CNA028202848A patent/CN1568324A/zh active Pending
- 2002-09-13 BR BR0212794-6A patent/BR0212794A/pt not_active IP Right Cessation
- 2002-09-13 KR KR10-2004-7003754A patent/KR20040053125A/ko not_active Withdrawn
- 2002-09-13 EP EP02798231A patent/EP1432709B8/en not_active Expired - Lifetime
- 2002-09-13 AT AT02798231T patent/ATE300542T1/de not_active IP Right Cessation
- 2002-09-13 IL IL16081002A patent/IL160810A0/xx unknown
- 2002-09-13 MX MXPA04002323A patent/MXPA04002323A/es unknown
- 2002-09-13 JP JP2003526921A patent/JP2005504795A/ja active Pending
- 2002-09-13 NZ NZ531700A patent/NZ531700A/en unknown
- 2002-09-13 CA CA002459886A patent/CA2459886A1/en not_active Abandoned
-
2004
- 2004-03-11 IS IS7176A patent/IS7176A/is unknown
- 2004-03-11 ZA ZA200401996A patent/ZA200401996B/xx unknown
- 2004-03-11 NO NO20041035A patent/NO20041035L/no not_active Application Discontinuation
- 2004-05-20 US US10/849,978 patent/US20040214850A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL160810A0 (en) | 2004-08-31 |
| CA2459886A1 (en) | 2003-03-20 |
| NO20041035L (no) | 2004-04-30 |
| AU2002333626B2 (en) | 2006-06-29 |
| DE60205265T2 (de) | 2006-03-30 |
| KR20040053125A (ko) | 2004-06-23 |
| ZA200401996B (en) | 2005-05-31 |
| MXPA04002323A (es) | 2005-04-08 |
| EP1432709B1 (en) | 2005-07-27 |
| EP1432709A1 (en) | 2004-06-30 |
| US6861436B2 (en) | 2005-03-01 |
| JP2005504795A (ja) | 2005-02-17 |
| EP1432709B8 (en) | 2005-11-02 |
| IS7176A (is) | 2004-03-11 |
| ES2245747T3 (es) | 2006-01-16 |
| WO2003022846A1 (en) | 2003-03-20 |
| HK1063322A1 (en) | 2004-12-24 |
| DE60205265D1 (de) | 2005-09-01 |
| BR0212794A (pt) | 2004-10-05 |
| CN1568324A (zh) | 2005-01-19 |
| ATE300542T1 (de) | 2005-08-15 |
| US20030153759A1 (en) | 2003-08-14 |
| NZ531700A (en) | 2006-10-27 |
| US20040214850A1 (en) | 2004-10-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1432709E (pt) | Indolizinas de 1-glioxilamida para o trtamento do cancro | |
| AR043158A1 (es) | Compuestos activadores de glucoquinasa de amida tri(ciclo) sustituidos, procedimientos para su preparacion y composiciones farmaceuticas que los contienen | |
| HRP20050688A2 (en) | Pyrimidine derivatives for the prevention of hiv infection | |
| NO20050418L (no) | Kondenserte pyridiner og pyrimidiner med TIE2(TEK) aktivitet | |
| NO20042584L (no) | Dibenzylaminforbindelser og farmasoytisk anvendelse derav | |
| PE20030746A1 (es) | DERIVADOS DE PIRIDO [2,1-a] ISOQUINOLINA | |
| CO4970713A1 (es) | Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen | |
| TW200800949A (en) | Macrocylic inhibitors of hepatitis C virus | |
| AR049331A1 (es) | Derivados de imidazopiridinas, imidazoquinolinas e iimidazonaftiridinas sustituidas con amidas como moduladores de biosintesis de citoquinas. composiciones farmaceuticas. | |
| CY1108341T1 (el) | Η ΧΡΗΣΗ ΤΩΝ 2-ΦΘΟΡΟ-3-ΚΕΤΟΕΣΤΕΡΩΝ ΓΙΑ ΤΗΝ ΠΑΡΑΣΚΕΥΗ ΤΩΝ 3-ΦΘΟΡΟ-6,7,8,9-ΤΕΤΡΑΫΔΡΟ-4-Η-ΠΥΡΙΜΙΔΟ[1,2-α]ΠΥΡΙΜΙΔΙΝ-4-ΟΝΩΝ | |
| CO5590895A2 (es) | Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos | |
| ES2038678T3 (es) | Procedimiento para la preparacion de n-(2-alquil-3-mercapto-glutaril)-alfamino-acidos. | |
| DK471586D0 (da) | 3-vinyl- og 3-ethynyl-beta-carbolinderivater, deres fremstilling og deres anvendelse som laegemiddel | |
| CA2461060A1 (en) | Method for preparing pyrimidinone compound and pharmaceutically acceptable salts thereof | |
| GB0401336D0 (en) | Organic compounds | |
| HUP0201475A2 (hu) | Heteroarilamidin-, metilamidin- és guanidinszármazékok, előállításuk és alkalmazásuk, valamint e vegyületeket tartalmazó gyógyászati készítmények | |
| CO5690577A2 (es) | Derivados de imidazoquinolina como ligandos receptores de adenosina a3 | |
| DK118287D0 (da) | Heteroaryloxy-beta-carbolinderivater, deres fremstilling og deres anvendelse som laegemiddel | |
| DK1303512T3 (da) | Fremgangsmåde til fremstilling af arylacetylaminothiazoler | |
| DK543886A (da) | Phenoxysubstituerede beta-carbolinderivater, deres fremstilling ogderes anvendelse som laegemiddel | |
| AR036735A1 (es) | Derivados de 5-metoxi-8-aril-[1,2,4]triazolo[1,5-a]piridina | |
| TW200602039A (en) | 1-Glyoxylamide indolizines for treating lung and ovarian cancer | |
| Schantl et al. | Expedient synthesis of N-substituted 2-aminothiazoles | |
| AR056418A1 (es) | Derivados de bencimidazol como 5-ht6, 5-ht2a, metodo para la obtencion del compuesto y el uso para la fabricacion de un mediicamento | |
| ES435955A1 (es) | Un procedimiento para obtener un derivado de pirido (3,4-d) piridezina. |