PT1401442E - S-omeprazolo (complexo de inclusao de esomeprazolo com ciclodextrinas) - Google Patents
S-omeprazolo (complexo de inclusao de esomeprazolo com ciclodextrinas)Info
- Publication number
- PT1401442E PT1401442E PT02776528T PT02776528T PT1401442E PT 1401442 E PT1401442 E PT 1401442E PT 02776528 T PT02776528 T PT 02776528T PT 02776528 T PT02776528 T PT 02776528T PT 1401442 E PT1401442 E PT 1401442E
- Authority
- PT
- Portugal
- Prior art keywords
- omeprazolo
- esomeprazole
- cyclodextrins
- inclusion complex
- cyclodextrin
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0113792A GB2376231A (en) | 2001-06-06 | 2001-06-06 | Benzimidazole-cyclodextrin inclusion complex |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1401442E true PT1401442E (pt) | 2005-02-28 |
Family
ID=9916040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT02776528T PT1401442E (pt) | 2001-06-06 | 2002-06-06 | S-omeprazolo (complexo de inclusao de esomeprazolo com ciclodextrinas) |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20040147481A1 (pt) |
| EP (1) | EP1401442B1 (pt) |
| JP (1) | JP2004536810A (pt) |
| AT (1) | ATE282412T1 (pt) |
| AU (1) | AU2002344386B2 (pt) |
| CA (1) | CA2449769C (pt) |
| DE (1) | DE60201995T2 (pt) |
| ES (1) | ES2232780T3 (pt) |
| GB (1) | GB2376231A (pt) |
| HK (1) | HK1064602A1 (pt) |
| LT (1) | LT5182B (pt) |
| LV (1) | LV13154B (pt) |
| NZ (1) | NZ529956A (pt) |
| PL (1) | PL366940A1 (pt) |
| PT (1) | PT1401442E (pt) |
| RU (1) | RU2313343C2 (pt) |
| WO (1) | WO2002098423A1 (pt) |
| ZA (1) | ZA200309841B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1707217A1 (en) | 2004-12-17 | 2006-10-04 | Wacker Chemie AG | Process for preparing an alpha lipoic acid/cyclodextrin complex and product prepared |
| US20060229277A1 (en) * | 2005-04-08 | 2006-10-12 | Orbus Pharma, Inc. | Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor |
| ES2325336T3 (es) * | 2005-12-28 | 2009-09-01 | Union Quimico-Farmaceutica, S.A. | Procedimiento para la preparacion del enantiomero (s) de omeprazol. |
| KR20070069567A (ko) * | 2005-12-28 | 2007-07-03 | 에스케이케미칼주식회사 | 저장안정성이 우수한 ｓ-오메프라졸 함유 포접 복합체 및이의 제조방법 |
| DK2106397T3 (da) | 2007-09-25 | 2012-01-30 | Hetero Drugs Ltd | Fremgangsmåde til fremstilling af enantiomer-ren esomeprazol |
| WO2010097583A1 (en) * | 2009-02-24 | 2010-09-02 | Cipla Limited | Esomeprazole potassium polymorph and its preparation |
| CN104277030B (zh) * | 2013-07-03 | 2016-04-20 | 湖南理工学院 | 一种反应萃取分离泮托拉唑对映体的方法 |
| CN103768028A (zh) * | 2014-01-15 | 2014-05-07 | 山东新时代药业有限公司 | 一种注射用埃索美拉唑钠无菌冻干粉末及其制备工艺 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3427787A1 (de) * | 1984-07-27 | 1986-01-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Wirkstoffkomplexe von 5-methoxy-2((4-methoxy-3,5-dimethyl-2-pyridyl) methylsulfinyl)-1h-benzimidazol mit cyclodextrinen, deren herstellung und arzneimittel |
| TW224049B (pt) * | 1991-12-31 | 1994-05-21 | Sunkyong Ind Ltd | |
| US5877192A (en) * | 1993-05-28 | 1999-03-02 | Astra Aktiebolag | Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole |
| SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
| JPH0948730A (ja) * | 1995-06-02 | 1997-02-18 | Takeda Chem Ind Ltd | 水溶性の改善されたベンズイミダゾール系抗潰瘍剤含有安定組成物 |
| WO1996038175A1 (en) * | 1995-06-02 | 1996-12-05 | Takeda Chemical Industries, Ltd. | Stabilized composition comprising an antiulcerative benzimidazole |
| SE510666C2 (sv) | 1996-12-20 | 1999-06-14 | Astra Ab | Nya Kristallmodifikationer |
| CZ291842B6 (cs) * | 1997-03-13 | 2003-06-18 | Hexal Ag | Farmaceutická formulace |
| PT1018340E (pt) * | 1999-01-06 | 2003-12-31 | Tecnimede Sociedade Tecnico Medicinal Sa | Complexos de inclusao de sais de aminoacidos de derivados do benzimidazol com ciclodextrinas, sua preparacao e formulacoes farmaceuticas que os contem |
| JP4312405B2 (ja) * | 1999-08-26 | 2009-08-12 | エイエイアイファーマ・インコーポレイテッド | アルコキシ置換ベンズイミダゾール化合物、それを含む医薬製剤物、およびそれを使用する方法 |
| US6262085B1 (en) * | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| SE9903831D0 (sv) * | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
-
2001
- 2001-06-06 GB GB0113792A patent/GB2376231A/en not_active Withdrawn
-
2002
- 2002-06-06 ES ES02776528T patent/ES2232780T3/es not_active Expired - Lifetime
- 2002-06-06 JP JP2003501462A patent/JP2004536810A/ja active Pending
- 2002-06-06 AU AU2002344386A patent/AU2002344386B2/en not_active Ceased
- 2002-06-06 DE DE60201995T patent/DE60201995T2/de not_active Expired - Lifetime
- 2002-06-06 WO PCT/GB2002/002542 patent/WO2002098423A1/en active IP Right Grant
- 2002-06-06 EP EP02776528A patent/EP1401442B1/en not_active Expired - Lifetime
- 2002-06-06 US US10/479,658 patent/US20040147481A1/en not_active Abandoned
- 2002-06-06 CA CA2449769A patent/CA2449769C/en not_active Expired - Fee Related
- 2002-06-06 RU RU2003137221/15A patent/RU2313343C2/ru not_active IP Right Cessation
- 2002-06-06 PL PL02366940A patent/PL366940A1/xx not_active Application Discontinuation
- 2002-06-06 PT PT02776528T patent/PT1401442E/pt unknown
- 2002-06-06 AT AT02776528T patent/ATE282412T1/de not_active IP Right Cessation
- 2002-06-06 NZ NZ529956A patent/NZ529956A/en unknown
-
2003
- 2003-12-03 LT LT2003100A patent/LT5182B/lt not_active IP Right Cessation
- 2003-12-19 ZA ZA200309841A patent/ZA200309841B/en unknown
-
2004
- 2004-01-06 LV LVP-04-01A patent/LV13154B/en unknown
- 2004-09-30 HK HK04107536A patent/HK1064602A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2449769C (en) | 2010-12-14 |
| US20040147481A1 (en) | 2004-07-29 |
| NZ529956A (en) | 2005-07-29 |
| ZA200309841B (en) | 2005-03-14 |
| JP2004536810A (ja) | 2004-12-09 |
| RU2003137221A (ru) | 2005-06-10 |
| LT5182B (lt) | 2004-12-27 |
| PL366940A1 (en) | 2005-02-07 |
| ES2232780T3 (es) | 2005-06-01 |
| RU2313343C2 (ru) | 2007-12-27 |
| GB0113792D0 (en) | 2001-07-25 |
| HK1064602A1 (en) | 2005-02-04 |
| EP1401442B1 (en) | 2004-11-17 |
| LT2003100A (en) | 2004-09-27 |
| GB2376231A (en) | 2002-12-11 |
| DE60201995T2 (de) | 2005-11-24 |
| EP1401442A1 (en) | 2004-03-31 |
| ATE282412T1 (de) | 2004-12-15 |
| DE60201995D1 (de) | 2004-12-23 |
| AU2002344386B2 (en) | 2006-11-30 |
| WO2002098423A1 (en) | 2002-12-12 |
| CA2449769A1 (en) | 2002-12-12 |
| LV13154B (en) | 2004-07-20 |
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