PT1372686E - Metodos e composicoes para a sintese de peptidos - Google Patents

Metodos e composicoes para a sintese de peptidos

Info

Publication number
PT1372686E
PT1372686E PT00992116T PT00992116T PT1372686E PT 1372686 E PT1372686 E PT 1372686E PT 00992116 T PT00992116 T PT 00992116T PT 00992116 T PT00992116 T PT 00992116T PT 1372686 E PT1372686 E PT 1372686E
Authority
PT
Portugal
Prior art keywords
compositions
methods
peptid
synthesis
peptid synthesis
Prior art date
Application number
PT00992116T
Other languages
English (en)
Portuguese (pt)
Inventor
Marc W Andersen
Bray Brian
Paul E Friedrich
Kang Myung-Chol
Original Assignee
Trimeris Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trimeris Inc filed Critical Trimeris Inc
Publication of PT1372686E publication Critical patent/PT1372686E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT00992116T 1999-07-07 2000-07-05 Metodos e composicoes para a sintese de peptidos PT1372686E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/349,205 US6469136B1 (en) 1999-07-07 1999-07-07 Methods and composition for peptide synthesis

Publications (1)

Publication Number Publication Date
PT1372686E true PT1372686E (pt) 2005-05-31

Family

ID=23371340

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00992116T PT1372686E (pt) 1999-07-07 2000-07-05 Metodos e composicoes para a sintese de peptidos

Country Status (17)

Country Link
US (2) US6469136B1 (enExample)
EP (1) EP1372686B1 (enExample)
JP (1) JP2003530311A (enExample)
KR (1) KR100631874B1 (enExample)
CN (1) CN1267449C (enExample)
AR (1) AR024686A1 (enExample)
AT (1) ATE288278T1 (enExample)
AU (1) AU4133701A (enExample)
BR (1) BR0012249A (enExample)
CA (1) CA2378086A1 (enExample)
DE (1) DE60017955T2 (enExample)
DK (1) DK1372686T3 (enExample)
ES (1) ES2236043T3 (enExample)
MX (1) MXPA02000021A (enExample)
PT (1) PT1372686E (enExample)
TW (1) TWI237640B (enExample)
WO (1) WO2001034635A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656906B1 (en) * 1998-05-20 2003-12-02 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
SK782002A3 (en) * 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
NZ537493A (en) * 2002-07-24 2007-05-31 Hoffmann La Roche Pegylated T1249 polypeptide
US20040158037A1 (en) * 2003-02-12 2004-08-12 Bohling James Charles Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith
AU2004200485A1 (en) * 2003-02-25 2004-09-09 Rohm And Haas Company Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
US7348004B2 (en) 2003-05-06 2008-03-25 Syntonix Pharmaceuticals, Inc. Immunoglobulin chimeric monomer-dimer hybrids
ATE497783T1 (de) * 2003-05-06 2011-02-15 Syntonix Pharmaceuticals Inc Gerinnungsfaktor vii-fc chimäre proteine zur behandlung von hämostatischen krankheiten
DE602004017057D1 (de) * 2003-12-31 2008-11-20 Hoffmann La Roche Verfahren und systeme zur rückgewinnung von peptiden
EP1701976A2 (en) * 2003-12-31 2006-09-20 F.Hoffmann-La Roche Ag Peptide synthesis and deprotection with co-solvent
WO2005063792A2 (en) * 2003-12-31 2005-07-14 F. Hoffmann-La Roche Ag Methods for recovering cleaved peptide from a support
EP1701971A2 (en) * 2003-12-31 2006-09-20 F.Hoffmann-La Roche Ag Peptide synthesis using decanting filter
EP1701969B1 (en) * 2003-12-31 2007-10-24 F.Hoffmann-La Roche Ag Process for peptide synthesis using a reduced amount of deprotection agent
CN101132812A (zh) * 2004-03-15 2008-02-27 阿拉巴马耐科塔医药公司 Hiv进入抑制剂的聚合物基组合物和结合物
CA2593866C (en) * 2004-12-30 2013-08-06 F. Hoffmann-La Roche Ag Synthesis of peptide t-1249 using peptide intermediate fragments
CA2592438C (en) * 2004-12-30 2013-09-03 F.Hoffmann-La Roche Ag Synthesis of peptide t-20 using peptide intermediate fragments
WO2006069779A1 (en) * 2004-12-30 2006-07-06 F. Hoffmann-La Roche Ag Preparing of peptides with excellent solubility
WO2006069697A1 (en) * 2004-12-30 2006-07-06 F. Hoffmann-La Roche Ag Colorimetrically assessing peptide characteristics
WO2006105199A2 (en) * 2005-03-30 2006-10-05 Trimeris, Inc. Compositions and methods for synthesis of peptide and related conjugate
TW200745163A (en) 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
CA2651070A1 (en) 2006-05-03 2007-11-15 Mallinckrodt Inc. Composition and method for the release of protected peptides from a resin
CN101195653B (zh) * 2006-12-08 2010-05-12 吉尔生化（上海）有限公司 亮丙瑞林的固液合成法
JP2010535788A (ja) * 2007-08-09 2010-11-25 シントニックス・ファーマシューティカルズ・インコーポレーテッド 免疫調節性ペプチド
BRPI0817697A2 (pt) * 2007-09-25 2015-04-07 Trimeris Inc Método de síntese de um peptídeo, conjunto de fragmentos de peptídeo, e, peptídeo
JP5473925B2 (ja) * 2007-10-27 2014-04-16 コーデン ファーマ コロラド インコーポレイテッド 固相および溶液相の組み合わせ技法を使用するインスリン分泌性ペプチドの合成
AU2008334783A1 (en) * 2007-12-11 2009-06-18 F. Hoffmann-La Roche Ag Insulinotropic peptide synthesis using solid and solution phase combination techniques
WO2010014909A1 (en) * 2008-08-01 2010-02-04 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
SI2591006T1 (sl) 2010-07-09 2019-10-30 Bioverativ Therapeutics Inc Enoverižne molekule, ki jih lahko obdelujemo in polipeptidi izdelani z njihovo uporabo
CN102268065A (zh) * 2011-06-23 2011-12-07 成都圣诺科技发展有限公司 氨基保护丝氨酸寡肽及其制备方法和用途
CN102603869B (zh) * 2012-03-27 2013-03-27 西安华澳丽康生物工程有限公司 六胜肽的合成方法
TWI745671B (zh) 2013-03-15 2021-11-11 美商百歐維拉提夫治療公司 因子ｉｘ多肽調配物
AU2014234400B2 (en) 2013-03-21 2017-11-16 Sanofi-Aventis Deutschland Gmbh Synthesis of hydantoin containing peptide products
DK2976325T3 (en) 2013-03-21 2017-06-06 Sanofi Aventis Deutschland SYNTHESIS OF PEPTIDE PRODUCTS CONTAINING CYCLIC IMID
CN108572171A (zh) * 2017-03-10 2018-09-25 江苏金斯瑞生物科技有限公司 一种检测哌啶残留的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994002505A1 (en) * 1992-07-20 1994-02-03 Duke University Compounds which inhibit hiv replication
CA2150371C (en) 1992-12-11 2002-09-17 Dov Borovsky Materials and methods for control of pests
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
EP0708659A4 (en) 1993-06-07 2000-08-23 Genentech Inc HIV ENVELOPE POLYPEPTIDE
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
DE69926061T2 (de) * 1998-03-23 2006-06-01 Trimeris Inc. Verfahren und zusammensetzungen zur peptidsynthese (t-20)
US6258782B1 (en) * 1998-05-20 2001-07-10 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
US6217666B1 (en) 1998-08-31 2001-04-17 Danieli Technology, Inc. Countercurrent reduction of oxides on moving metal

Also Published As

Publication number Publication date
CA2378086A1 (en) 2001-05-17
EP1372686A2 (en) 2004-01-02
CN1450906A (zh) 2003-10-22
DE60017955D1 (de) 2005-03-10
ATE288278T1 (de) 2005-02-15
WO2001034635A3 (en) 2003-10-16
WO2001034635A2 (en) 2001-05-17
BR0012249A (pt) 2003-11-11
EP1372686A4 (en) 2004-01-02
TWI237640B (en) 2005-08-11
MXPA02000021A (es) 2002-07-02
KR20020038676A (ko) 2002-05-23
ES2236043T3 (es) 2005-07-16
US6469136B1 (en) 2002-10-22
WO2001034635A9 (en) 2002-08-01
AU4133701A (en) 2001-06-06
US20030125516A1 (en) 2003-07-03
EP1372686B1 (en) 2005-02-02
AR024686A1 (es) 2002-10-23
US6767993B2 (en) 2004-07-27
KR100631874B1 (ko) 2006-10-09
JP2003530311A (ja) 2003-10-14
CN1267449C (zh) 2006-08-02
DK1372686T3 (da) 2005-05-30
DE60017955T2 (de) 2006-01-12

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