PT1268387E - Formas especificas de sais de derivados de trifeniletileno como moduladores selectivos de rceptores de estrogenio - Google Patents

Formas especificas de sais de derivados de trifeniletileno como moduladores selectivos de rceptores de estrogenio

Info

Publication number
PT1268387E
PT1268387E PT01926670T PT01926670T PT1268387E PT 1268387 E PT1268387 E PT 1268387E PT 01926670 T PT01926670 T PT 01926670T PT 01926670 T PT01926670 T PT 01926670T PT 1268387 E PT1268387 E PT 1268387E
Authority
PT
Portugal
Prior art keywords
trifenylethylene
derivatives
salts
selective modulators
specified forms
Prior art date
Application number
PT01926670T
Other languages
English (en)
Inventor
Gary A Cain
Reginald O Cann
Christopher A Teleha
Denette K Murphy
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of PT1268387E publication Critical patent/PT1268387E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
PT01926670T 2000-04-05 2001-04-05 Formas especificas de sais de derivados de trifeniletileno como moduladores selectivos de rceptores de estrogenio PT1268387E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19458000P 2000-04-05 2000-04-05

Publications (1)

Publication Number Publication Date
PT1268387E true PT1268387E (pt) 2004-09-30

Family

ID=22718126

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01926670T PT1268387E (pt) 2000-04-05 2001-04-05 Formas especificas de sais de derivados de trifeniletileno como moduladores selectivos de rceptores de estrogenio

Country Status (12)

Country Link
US (1) US6417394B2 (pt)
EP (1) EP1268387B1 (pt)
JP (1) JP2004507452A (pt)
AT (1) ATE269291T1 (pt)
AU (2) AU2001253191B2 (pt)
CA (1) CA2403263A1 (pt)
DE (1) DE60103867T2 (pt)
DK (1) DK1268387T3 (pt)
ES (1) ES2222988T3 (pt)
PT (1) PT1268387E (pt)
TR (1) TR200401601T4 (pt)
WO (1) WO2001077055A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002323098A1 (en) 2001-08-11 2003-03-03 Bristol-Myers Squibb Pharma Company Selective estrogen receptor modulators
EP1692127B1 (en) 2003-10-08 2008-07-02 Smithkline Beecham Corporation Triphenylethylene compounds as selective estrogen receptor modulators
US7196119B2 (en) * 2003-10-21 2007-03-27 The Regents Of The University Of California Development of new selective estrogen receptor modulators
US7425580B2 (en) * 2004-05-19 2008-09-16 Wyeth (Diaryl-methyl)-malononitriles and their use as estrogen receptor ligands
US20080234199A1 (en) * 2005-11-22 2008-09-25 Smithkline Beecham Corporation Chemical Compounds
WO2009120999A2 (en) * 2008-03-28 2009-10-01 Olema Pharmaceuticals, Inc. Use of an endoxifen prodrug for treatment of breast cancer
EP2802608A4 (en) * 2012-01-12 2015-08-05 Univ Yale COMPOUNDS AND METHODS FOR ENHANCED DEGRADATION OF TARGET PROTEINS AND OTHER POLYPEPTIDES BY E3 UBIQUITIN LIGASE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9208511D0 (en) * 1991-05-09 1992-06-03 Ici Plc Compounds
US5681835A (en) * 1994-04-25 1997-10-28 Glaxo Wellcome Inc. Non-steroidal ligands for the estrogen receptor
HUP0002852A3 (en) * 1997-08-15 2001-11-28 Univ Durham A method of preventing or treating estrogen-dependent diseases and disorders using triphenil-ethylene derivatives

Also Published As

Publication number Publication date
EP1268387B1 (en) 2004-06-16
ATE269291T1 (de) 2004-07-15
JP2004507452A (ja) 2004-03-11
CA2403263A1 (en) 2001-10-18
DE60103867D1 (de) 2004-07-22
WO2001077055A3 (en) 2002-05-30
US20020004496A1 (en) 2002-01-10
ES2222988T3 (es) 2005-02-16
US6417394B2 (en) 2002-07-09
EP1268387A2 (en) 2003-01-02
TR200401601T4 (tr) 2004-08-23
AU2001253191B2 (en) 2006-03-02
WO2001077055A2 (en) 2001-10-18
AU5319101A (en) 2001-10-23
DK1268387T3 (da) 2004-10-18
DE60103867T2 (de) 2005-06-30

Similar Documents

Publication Publication Date Title
DK1353672T3 (da) Syntese af 4-amino-thalidomidenantiomerer
DE69935335D1 (de) Pyrazole als modulatoren des östrogenrezeptors
WO2003016270A3 (en) Selective estrogen receptor modulators
HK1052500A1 (en) Pyridine derivatives inhibiting angiogenesis and/or vegf receptor tyrosine kinase
ATE269357T1 (de) Zusammensetzungen und verfahren zur krebsbehandlung durch die selektive hemmung von vegf
HK1098460A1 (en) Fused hetrocyclic compounds and their use as metabotropic receptor antagonists for the treatment of gastrointestinal disorders
WO2006126939A8 (en) Novel 8-sulfonylamino-3 aminosubstituted chroman or tetrahydronaphtalene derivatives modulating the 5ht6 receptor
IL153406A0 (en) Cyclopentanoindoles, compositions containing such compounds and methods of treatment
NO20031687D0 (no) Veksthormonsekretagoger
YU80902A (sh) Novi indolin-2-on derivati, njihovo dobijanje i farmaceuski oblici koji ih sadrže
DK1263752T3 (da) LPA-receptoragonister og -antagonister og fremgangsmåde til anvendelse heraf
DK1124842T3 (da) Betulinsyrederivater anvendelige til behandling af neuroektodermale tumorer
GT200200152A (es) Derivados de 2 pirrolidona como agonistas prostanoideos
PT1268387E (pt) Formas especificas de sais de derivados de trifeniletileno como moduladores selectivos de rceptores de estrogenio
ATE374190T1 (de) Tetrahydrochinazolinderivate als cfr-antagonisten
DE60105785D1 (de) Halogenierte triphenylethylene derivate als selektive östrogenrezeptormodulatoren
MXPA01008347A (es) Compuestos quimicos.
WO2008059514A3 (en) Process for preparing escitalopram
GB0425548D0 (en) Radiolabelled ligands
WO2004087673A3 (en) Migrastatin analogs and uses thereof
DE69906101D1 (de) 3-bicycloindole als liganden des 5-ht 1d rezeptors
MX2023004116A (es) Nuevos compuestos potentes y selectivos como moduladores del receptor de serotonina 1b.
TW200510390A (en) Benzimidazole derivatives and their use for modulating the GABAA receptor complex