PT1266967E - Processo para a producao de pravastatina e lovastatina - Google Patents

Processo para a producao de pravastatina e lovastatina

Info

Publication number
PT1266967E
PT1266967E PT01114462T PT01114462T PT1266967E PT 1266967 E PT1266967 E PT 1266967E PT 01114462 T PT01114462 T PT 01114462T PT 01114462 T PT01114462 T PT 01114462T PT 1266967 E PT1266967 E PT 1266967E
Authority
PT
Portugal
Prior art keywords
pravastatin
production
lovastatin
aspergillus
exocellular
Prior art date
Application number
PT01114462T
Other languages
English (en)
Inventor
Alberto Benedetti
Matilde Manzoni
Marina Nichele
Manuela Rollini
Original Assignee
Gnosis Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Srl filed Critical Gnosis Srl
Publication of PT1266967E publication Critical patent/PT1266967E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pyrane Compounds (AREA)
PT01114462T 2001-06-15 2001-06-15 Processo para a producao de pravastatina e lovastatina PT1266967E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01114462A EP1266967B1 (en) 2001-06-15 2001-06-15 Process for the production of pravastatin and lovastatin

Publications (1)

Publication Number Publication Date
PT1266967E true PT1266967E (pt) 2004-05-31

Family

ID=8177727

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01114462T PT1266967E (pt) 2001-06-15 2001-06-15 Processo para a producao de pravastatina e lovastatina

Country Status (7)

Country Link
EP (1) EP1266967B1 (pt)
AT (1) ATE258603T1 (pt)
DE (1) DE60101904T2 (pt)
DK (1) DK1266967T3 (pt)
ES (1) ES2210066T3 (pt)
PT (1) PT1266967E (pt)
TR (1) TR200400357T4 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2029750T1 (sl) * 2006-06-22 2011-11-30 Dsm Ip Assets Bv Proizvajanje pravastatina
WO2009077523A2 (en) * 2007-12-18 2009-06-25 Dsm Ip Assets B.V. Improved statin production
JP6916482B2 (ja) * 2016-06-23 2021-08-11 学校法人日本大学 アスペルギルス・テレウス検出用プローブ、及びアスペルギルス・テレウスの検出方法
CN112553262B (zh) * 2020-12-31 2023-04-07 广东蓝宝制药有限公司 一种普伐他汀的发酵工艺
CN113061536B (zh) * 2021-03-17 2022-08-23 江南大学 一株高产洛伐他汀的紫色红曲菌z-27及其应用
CN114958625B (zh) * 2022-07-07 2023-12-19 福安药业集团烟台只楚药业有限公司 一种发酵生产洛伐他汀的土曲霉的培养与保存方法
CN116925926B (zh) * 2023-07-14 2024-02-02 中国农业大学 富硒红色红曲霉发酵生产洛伐他汀的方法

Also Published As

Publication number Publication date
TR200400357T4 (tr) 2004-03-22
DK1266967T3 (da) 2004-05-03
DE60101904T2 (de) 2004-07-15
DE60101904D1 (de) 2004-03-04
EP1266967A1 (en) 2002-12-18
ATE258603T1 (de) 2004-02-15
ES2210066T3 (es) 2004-07-01
EP1266967B1 (en) 2004-01-28

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