PT1266887E - Derivados de indenoindolonas, processo para a sua preparacao e as composicoes farmaceuticas que os contem - Google Patents

Derivados de indenoindolonas, processo para a sua preparacao e as composicoes farmaceuticas que os contem

Info

Publication number
PT1266887E
PT1266887E PT02291463T PT02291463T PT1266887E PT 1266887 E PT1266887 E PT 1266887E PT 02291463 T PT02291463 T PT 02291463T PT 02291463 T PT02291463 T PT 02291463T PT 1266887 E PT1266887 E PT 1266887E
Authority
PT
Portugal
Prior art keywords
alkyl
aryl
optionally substituted
groups
alkoxy
Prior art date
Application number
PT02291463T
Other languages
English (en)
Inventor
Michel Wierzbicki
Stephane Leonce
Marie-Francoise Boussard
Alain Pierre
Laurence Kraus-Berthier
Ghanem Atassi
Anne Rousseau
John Hickman
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of PT1266887E publication Critical patent/PT1266887E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT02291463T 2001-06-13 2002-06-12 Derivados de indenoindolonas, processo para a sua preparacao e as composicoes farmaceuticas que os contem PT1266887E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0107718A FR2826009B1 (fr) 2001-06-13 2001-06-13 Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
PT1266887E true PT1266887E (pt) 2005-10-31

Family

ID=8864253

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02291463T PT1266887E (pt) 2001-06-13 2002-06-12 Derivados de indenoindolonas, processo para a sua preparacao e as composicoes farmaceuticas que os contem

Country Status (26)

Country Link
US (1) US6627650B2 (pt)
EP (1) EP1266887B1 (pt)
JP (1) JP3837090B2 (pt)
KR (1) KR100466068B1 (pt)
CN (1) CN1156446C (pt)
AR (1) AR034471A1 (pt)
AT (1) ATE302183T1 (pt)
AU (1) AU781768B2 (pt)
BR (1) BR0202279A (pt)
CA (1) CA2389766C (pt)
CZ (1) CZ20022083A3 (pt)
DE (1) DE60205538T2 (pt)
DK (1) DK1266887T3 (pt)
EA (1) EA004571B1 (pt)
ES (1) ES2247282T3 (pt)
FR (1) FR2826009B1 (pt)
HK (1) HK1052172A1 (pt)
HU (1) HUP0201992A3 (pt)
MX (1) MXPA02005808A (pt)
NO (1) NO322709B1 (pt)
NZ (1) NZ519522A (pt)
PL (1) PL354472A1 (pt)
PT (1) PT1266887E (pt)
SI (1) SI1266887T1 (pt)
SK (1) SK286055B6 (pt)
ZA (1) ZA200204757B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
EP3147323B2 (de) 2015-09-28 2022-12-28 Henkel AG & Co. KGaA Thermisch expandierbare zusammensetzungen mit polysaccharid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6256471A (ja) * 1985-09-05 1987-03-12 Teikoku Hormone Mfg Co Ltd 含窒素四環式化合物
SE8902274D0 (sv) * 1989-06-22 1989-06-22 Univ Cincinnati Indenoidole compounds ii
SE8902273D0 (sv) * 1989-06-22 1989-06-22 Univ Cincinnati Indenoindole compounds i
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
US6069153A (en) * 1998-05-12 2000-05-30 American Home Products Corporation Indenoindoles and benzocarbazoles as estrogenic agents
FR2821843B1 (fr) * 2001-03-12 2003-05-09 Servier Lab Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
US20030125369A1 (en) 2003-07-03
AU781768B2 (en) 2005-06-09
JP2003012644A (ja) 2003-01-15
SK8342002A3 (en) 2003-01-09
US6627650B2 (en) 2003-09-30
CN1390834A (zh) 2003-01-15
AR034471A1 (es) 2004-02-25
DK1266887T3 (da) 2005-10-31
EA004571B1 (ru) 2004-06-24
ES2247282T3 (es) 2006-03-01
NO20022794D0 (no) 2002-06-12
ZA200204757B (en) 2003-02-17
CA2389766A1 (fr) 2002-12-13
AU4590302A (en) 2002-12-19
BR0202279A (pt) 2003-04-29
FR2826009A1 (fr) 2002-12-20
SK286055B6 (sk) 2008-02-05
ATE302183T1 (de) 2005-09-15
KR100466068B1 (ko) 2005-01-13
EP1266887A3 (fr) 2003-07-02
NO322709B1 (no) 2006-11-27
KR20020094914A (ko) 2002-12-18
PL354472A1 (en) 2002-12-16
HU0201992D0 (pt) 2002-08-28
HUP0201992A3 (en) 2004-04-28
SI1266887T1 (sl) 2005-12-31
EP1266887B1 (fr) 2005-08-17
EA200200563A1 (ru) 2002-12-26
CA2389766C (fr) 2007-09-25
DE60205538T2 (de) 2006-06-14
EP1266887A2 (fr) 2002-12-18
HUP0201992A2 (hu) 2003-04-28
NZ519522A (en) 2003-11-28
CZ20022083A3 (cs) 2003-04-16
JP3837090B2 (ja) 2006-10-25
CN1156446C (zh) 2004-07-07
FR2826009B1 (fr) 2003-08-15
DE60205538D1 (de) 2005-09-22
MXPA02005808A (es) 2004-12-13
NO20022794L (no) 2002-12-16
HK1052172A1 (en) 2003-09-05

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