PT1165797E - Partículas para a terapia genética - Google Patents

Partículas para a terapia genética Download PDF

Info

Publication number
PT1165797E
PT1165797E PT00909000T PT00909000T PT1165797E PT 1165797 E PT1165797 E PT 1165797E PT 00909000 T PT00909000 T PT 00909000T PT 00909000 T PT00909000 T PT 00909000T PT 1165797 E PT1165797 E PT 1165797E
Authority
PT
Portugal
Prior art keywords
particles
protein
gene therapy
virus
envelope
Prior art date
Application number
PT00909000T
Other languages
English (en)
Inventor
Eberhard Hildt
Peter Hofschneider
Original Assignee
Diaferon Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diaferon Gmbh filed Critical Diaferon Gmbh
Publication of PT1165797E publication Critical patent/PT1165797E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10141—Use of virus, viral particle or viral elements as a vector
    • C12N2730/10143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/40—Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source
    • C12N2810/405—Vectors comprising RGD peptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT00909000T 1999-02-05 2000-02-04 Partículas para a terapia genética PT1165797E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19904800A DE19904800C1 (de) 1999-02-05 1999-02-05 Partikel zur Gentherapie

Publications (1)

Publication Number Publication Date
PT1165797E true PT1165797E (pt) 2008-10-30

Family

ID=7896602

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00909000T PT1165797E (pt) 1999-02-05 2000-02-04 Partículas para a terapia genética

Country Status (9)

Country Link
US (1) US7018826B1 (pt)
EP (1) EP1165797B1 (pt)
AT (1) ATE402261T1 (pt)
CY (1) CY1107431T1 (pt)
DE (2) DE19904800C1 (pt)
DK (1) DK1165797T3 (pt)
ES (1) ES2310988T3 (pt)
PT (1) PT1165797E (pt)
WO (1) WO2000046376A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19850718C1 (de) 1998-11-03 2000-05-18 Hildt Eberhardt Zellpermeabilität-vermittelndes Polypeptid
JP2003286199A (ja) * 2002-03-29 2003-10-07 Japan Science & Technology Corp タンパク質中空ナノ粒子を用いる肝臓疾患治療用薬剤
US8101189B2 (en) 2002-07-05 2012-01-24 Folia Biotech Inc. Vaccines and immunopotentiating compositions and methods for making and using them
MXPA05000287A (es) * 2002-07-05 2005-09-08 Leclerc Denis Particula viral adyuvante.
DE10240894A1 (de) * 2002-09-04 2004-03-11 Procom Biotechnologische Produktions Gmbh Verstärkung der Resorption von Subtanzen über die Haut und Schleimhaut
KR101253261B1 (ko) * 2011-05-11 2013-04-10 한국과학기술연구원 ｓｉＲＮＡ 의 전달을 위한 재조합 단백질 및 이를 포함하는 조성물
CN108611395A (zh) * 2016-12-12 2018-10-02 中山大学 一种抗人乙肝病毒药物的筛选方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3940293A (en) 1992-04-03 1993-11-08 Alexander T. YOUNG Gene therapy using targeted viral vectors
JP2001519647A (ja) * 1995-12-28 2001-10-23 カイロン コーポレイション 標的細胞中へのウイルスおよび粒子の取り込みおよびインターナリゼーションのためのレセプター特異的キメラウイルス表面ポリペプチド
DE19850718C1 (de) 1998-11-03 2000-05-18 Hildt Eberhardt Zellpermeabilität-vermittelndes Polypeptid

Also Published As

Publication number Publication date
WO2000046376A2 (de) 2000-08-10
EP1165797A2 (de) 2002-01-02
WO2000046376A3 (de) 2000-11-16
EP1165797B1 (de) 2008-07-23
ATE402261T1 (de) 2008-08-15
DE19904800C1 (de) 2001-02-08
US7018826B1 (en) 2006-03-28
DE50015272D1 (de) 2008-09-04
ES2310988T3 (es) 2009-02-01
CY1107431T1 (el) 2012-12-19
DK1165797T3 (da) 2008-11-24

Similar Documents

Publication Publication Date Title
WO2000073316A3 (en) Virus immunologic determinants
CY1107431T1 (el) Σωματιδια για γoνιδιακη θεραπεια
WO2005003315A3 (en) Compositions and methods for peptide-assisted transfection
PL352332A1 (en) Expression and export of interferon-alpha proteins as fc fusion proteins
WO2002000730A3 (en) Pd-l2 molecules: novel pd-1 ligands and uses therefor
WO2005080556A3 (en) Virus purification methods
WO1999020766A3 (en) NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
UA42089C2 (uk) Протигрипозна вакцина на основі поверхневого антигену, спосіб її виробництва
PT1244805E (pt) Complexos de distribuicao de proteina-lipido cationico-acido nucleico do nucleo viral
WO2002006457A3 (en) Novel lipase genes
EP0859833A4 (en) RECOMBINANT HEPATITIS C VIRUS REPLICASE
DE69925618D1 (de) Rna krebsimpfstoff und verfahren zu dessen benutzung
AU7599500A (en) Novel gl50 molecules and uses therefor
EP1054683A4 (en) ANTIGENIC PEPTIDE COMPLEX / MODIFIED STRESS PROTEIN
WO2004024750A3 (en) Cd44-binding ligands
CA2379346A1 (en) Conjugate for mediating cell-specific, compartment-specific or membrane-specific transport of active substances
AU7093601A (en) Nucleic acid molecules encoding plant cell cycle proteins and uses therefor
WO2000075358A3 (en) Mammalian toll homologues and uses thereof
WO2001073028A3 (en) A p-selectin glycoprotein ligand (psgl-1) binding protein and uses therefor
WO2003004600A3 (en) Improvement of viral uptake into cells and tissues
EP1515738A4 (en) SCYTORIVINS AND CONJUGATES, FUSION PROTEINS, NUCLEIC ACIDS, VECTORS, HOST CELLS, COMPOSITIONS AND RELATED ANTIBODIES, AND METHODS OF USING SCYTOVIRINS
EE05691B1 (et) Ekspressioonivektorid ja nende rakendused
WO2001064912A3 (en) Triazine degrading enzymes
WO2000066743A3 (en) Viral expression vectors
WO2001049712A3 (en) Vaccine against isav (infectious salmon anaemia virus)