PT1140929E - 1h-imidazo¬4,5-d|piridazin-7-onas 3h-imidazo¬4,5-c|piridin-4-onas e as tionas correspondentes como ligandos receptores do factor de libertacao de corticotrofina (flc) - Google Patents

1h-imidazo¬4,5-d|piridazin-7-onas 3h-imidazo¬4,5-c|piridin-4-onas e as tionas correspondentes como ligandos receptores do factor de libertacao de corticotrofina (flc)

Info

Publication number
PT1140929E
PT1140929E PT99966736T PT99966736T PT1140929E PT 1140929 E PT1140929 E PT 1140929E PT 99966736 T PT99966736 T PT 99966736T PT 99966736 T PT99966736 T PT 99966736T PT 1140929 E PT1140929 E PT 1140929E
Authority
PT
Portugal
Prior art keywords
ones
factor
corticotrofin
imidazo4
flc
Prior art date
Application number
PT99966736T
Other languages
English (en)
Inventor
Rajagopal Bakthavatchalam
Paul Joseph Gilligan
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of PT1140929E publication Critical patent/PT1140929E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT99966736T 1998-12-30 1999-12-30 1h-imidazo¬4,5-d|piridazin-7-onas 3h-imidazo¬4,5-c|piridin-4-onas e as tionas correspondentes como ligandos receptores do factor de libertacao de corticotrofina (flc) PT1140929E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11418898P 1998-12-30 1998-12-30

Publications (1)

Publication Number Publication Date
PT1140929E true PT1140929E (pt) 2004-02-27

Family

ID=22353834

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99966736T PT1140929E (pt) 1998-12-30 1999-12-30 1h-imidazo¬4,5-d|piridazin-7-onas 3h-imidazo¬4,5-c|piridin-4-onas e as tionas correspondentes como ligandos receptores do factor de libertacao de corticotrofina (flc)

Country Status (10)

Country Link
US (2) US6271380B1 (pt)
EP (1) EP1140929B1 (pt)
AT (1) ATE251930T1 (pt)
AU (1) AU2222500A (pt)
CA (1) CA2351724A1 (pt)
DE (1) DE69912153T2 (pt)
DK (1) DK1140929T3 (pt)
ES (1) ES2209550T3 (pt)
PT (1) PT1140929E (pt)
WO (1) WO2000039127A1 (pt)

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Publication number Priority date Publication date Assignee Title
DE19837387A1 (de) * 1998-08-18 2000-02-24 Aventis Res & Tech Gmbh & Co 3'-Desoxypentopyranosyl-Nucleinsäure, ihre Herstellung und Verwendung
JP2004531475A (ja) 2001-01-26 2004-10-14 ブリストル−マイヤーズ　スクイブ　カンパニー コルチコトロピン放出因子阻害剤としてのイミダゾリル誘導体
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
RU2308457C2 (ru) 2001-04-27 2007-10-20 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Пиразоло [1, 5-а] пиридины и содержащие их лекарственные средства
JP2005526090A (ja) 2002-03-13 2005-09-02 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 神経伝達物質調節因子としてのピラゾロ（１，５−ａ）ピリジン誘導体
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
TWI283679B (en) 2002-10-22 2007-07-11 Eisai Co Ltd 7-phenylpyrazolopyridine compounds
US7176216B2 (en) 2002-10-22 2007-02-13 Eisai Co., Ltd. 7-phenylpyrazolopyridine compounds
SG149067A1 (en) 2003-12-22 2009-01-29 Leuven K U Res & Dev IMIDAZO[4,5-c]PYRIDINE COMPOUNDS AND METHODS OF ANTIVIRAL TREATMENT
US7572805B2 (en) 2004-07-14 2009-08-11 Bristol-Myers Squibb Company Pyrrolo(oxo)isoquinolines as 5HT ligands
ATE421518T1 (de) * 2005-02-10 2009-02-15 Bristol Myers Squibb Co Dihydrochinazolinone als 5ht-modulatoren
CN101268075A (zh) * 2005-07-28 2008-09-17 百时美施贵宝公司 作为5-羟色胺受体激动剂和拮抗剂的取代的四氢-1h吡啶并[4,3,b]吲哚
US7795436B2 (en) * 2005-08-24 2010-09-14 Bristol-Myers Squibb Company Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
NZ588376A (en) 2008-04-15 2011-06-30 Eisai R&D Man Co Ltd 3-phenylpyrazolo[5,1-b]thiazole compound having antagonism against corticotropin-releasing factor (CRF) receptor
AR078521A1 (es) 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
WO2013097052A1 (en) * 2011-12-30 2013-07-04 Abbott Laboratories Bromodomain inhibitors
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
AR096758A1 (es) * 2013-06-28 2016-02-03 Abbvie Inc Inhibidores cristalinos de bromodominios
CA2916542A1 (en) * 2013-06-28 2014-12-31 Abbvie Inc. Bromodomain inhibitors
MX2016007346A (es) * 2013-12-09 2016-09-13 Abbvie Inc Derivados de dihidropiridinona y dihidropiridazinona utiles como inhibidores de bromodominio.
EP3693369A3 (en) 2016-04-15 2020-09-09 AbbVie Inc. Bromodomain inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019715A1 (en) * 1990-06-15 1991-12-26 G.D. Searle & Co. 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS
CN1142817A (zh) 1993-10-12 1997-02-12 杜邦麦克制药有限公司 1n-烷基-n-芳基嘧啶胺及其衍生物
US5968944A (en) 1994-06-06 1999-10-19 Pfizer Inc. Substituted pyrazoles as corticotropin-releasing factor (CRF) antagonists
TW574214B (en) 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
EP0765327B1 (en) 1994-06-16 1999-07-21 Pfizer Inc. Pyrazolo and pyrrolopyridines
DK0778277T3 (da) 1995-12-08 2003-10-27 Pfizer Substituerede heterocycliske derivater som CRF antagonister
EP0970082A2 (en) * 1997-02-18 2000-01-12 Neurocrine Biosciences, Inc. Biazacyclic crf antagonists
US6143743A (en) * 1997-07-03 2000-11-07 Dupont Pharmaceuticals Company Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists

Also Published As

Publication number Publication date
EP1140929B1 (en) 2003-10-15
US6271380B1 (en) 2001-08-07
ES2209550T3 (es) 2004-06-16
CA2351724A1 (en) 2000-07-06
DK1140929T3 (da) 2004-02-16
EP1140929A4 (en) 2002-04-17
DE69912153D1 (de) 2003-11-20
EP1140929A1 (en) 2001-10-10
ATE251930T1 (de) 2003-11-15
US6518271B1 (en) 2003-02-11
AU2222500A (en) 2000-07-31
WO2000039127A1 (en) 2000-07-06
DE69912153T2 (de) 2004-08-26

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