US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
DE10034712A1
(de)
*
|
2000-07-17 |
2002-02-07 |
Arimedes Biotechnology Gmbh |
Verbrückte Glykokonjugate
|
DE10045047A1
(de)
*
|
2000-09-12 |
2002-03-21 |
Beate Kehrel |
Arzneimittel enthaltend aktiviertes Antithrombin III
|
US20050042714A1
(en)
*
|
2001-08-17 |
2005-02-24 |
Michael Pawlita |
Glycoconjugates of sialic acid derivates, methods for their production and use thereof
|
CA2461895A1
(en)
|
2001-09-26 |
2003-04-10 |
Werner Rutter |
Use of mannosamine derivatives for the stimulation of neurite growth
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
EP2292273A3
(en)
*
|
2001-10-10 |
2011-11-23 |
BioGeneriX AG |
Remodeling and glycoconjugation of peptides
|
US7179617B2
(en)
*
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
WO2004099231A2
(en)
*
|
2003-04-09 |
2004-11-18 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
CN101724075B
(zh)
*
|
2001-10-10 |
2014-04-30 |
诺和诺德公司 |
肽的重构和糖缀合
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7473680B2
(en)
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
MXPA04012496A
(es)
*
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
PT1543106E
(pt)
|
2002-07-15 |
2007-05-31 |
Immunex Corp |
Métodos e meios para controlar a sialilação de proteínas produzidas por células de mamíferos
|
AU2003303394B2
(en)
*
|
2002-12-23 |
2009-02-19 |
Bristol-Myers Squibb Company |
Product quality enhancement in mammalian cell culture processes for protein production
|
CA2519092C
(en)
*
|
2003-03-14 |
2014-08-05 |
Neose Technologies, Inc. |
Branched water-soluble polymers and their conjugates
|
EP1613261A4
(en)
*
|
2003-04-09 |
2011-01-26 |
Novo Nordisk As |
INTRA-CELLULAR FORMATION OF PEPTIDE CONJUGATES
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
AU2004240553A1
(en)
|
2003-05-09 |
2004-12-02 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
US9005625B2
(en)
|
2003-07-25 |
2015-04-14 |
Novo Nordisk A/S |
Antibody toxin conjugates
|
US7842661B2
(en)
*
|
2003-11-24 |
2010-11-30 |
Novo Nordisk A/S |
Glycopegylated erythropoietin formulations
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
CA2547140A1
(en)
*
|
2003-11-24 |
2005-06-09 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US20060040856A1
(en)
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
US20070254836A1
(en)
*
|
2003-12-03 |
2007-11-01 |
Defrees Shawn |
Glycopegylated Granulocyte Colony Stimulating Factor
|
NZ548123A
(en)
*
|
2004-01-08 |
2010-05-28 |
Novo Nordisk As |
O-linked glycosylation of peptides
|
RU2006138181A
(ru)
|
2004-05-04 |
2008-06-10 |
Ново Нордиск Хелс Кеа Аг (Ch) |
О-связанные гликоформы полипептидов и способ их изготовления
|
EP1771066A2
(en)
|
2004-07-13 |
2007-04-11 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 glp-1
|
EP1799249A2
(en)
*
|
2004-09-10 |
2007-06-27 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
US20080176790A1
(en)
*
|
2004-10-29 |
2008-07-24 |
Defrees Shawn |
Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf)
|
US20090054623A1
(en)
*
|
2004-12-17 |
2009-02-26 |
Neose Technologies, Inc. |
Lipo-Conjugation of Peptides
|
WO2006074279A1
(en)
*
|
2005-01-06 |
2006-07-13 |
Neose Technologies, Inc. |
Glycoconjugation using saccharyl fragments
|
US9029331B2
(en)
|
2005-01-10 |
2015-05-12 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
RU2287345C2
(ru)
*
|
2005-01-25 |
2006-11-20 |
Бизяев Алексей Вячеславович |
Средство для стимуляции выработки фактора viii свертывания крови
|
US20060211754A1
(en)
*
|
2005-03-16 |
2006-09-21 |
Yu Ruey J |
Compositions comprising N-propanoyl derivatives of amino acids, aminocarbohydrates and derivatives thereof
|
EP1866427A4
(en)
*
|
2005-03-30 |
2010-09-01 |
Novo Nordisk As |
MANUFACTURING PROCESS FOR THE PRODUCTION OF CULTIVE PEPTIDES IN CELL LINES OF INSECTS
|
EP1871795A4
(en)
|
2005-04-08 |
2010-03-31 |
Biogenerix Ag |
COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE
|
JP5216580B2
(ja)
|
2005-05-25 |
2013-06-19 |
ノヴォ ノルディスク アー/エス |
グリコペグ化第ix因子
|
EP1937719A4
(en)
*
|
2005-08-19 |
2010-11-24 |
Novo Nordisk As |
GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
WO2007056191A2
(en)
|
2005-11-03 |
2007-05-18 |
Neose Technologies, Inc. |
Nucleotide sugar purification using membranes
|
US7645860B2
(en)
*
|
2006-03-31 |
2010-01-12 |
Baxter Healthcare S.A. |
Factor VIII polymer conjugates
|
US7683158B2
(en)
|
2006-03-31 |
2010-03-23 |
Baxter International Inc. |
Pegylated factor VIII
|
US7982010B2
(en)
*
|
2006-03-31 |
2011-07-19 |
Baxter International Inc. |
Factor VIII polymer conjugates
|
US7985839B2
(en)
*
|
2006-03-31 |
2011-07-26 |
Baxter International Inc. |
Factor VIII polymer conjugates
|
US20080242607A1
(en)
*
|
2006-07-21 |
2008-10-02 |
Neose Technologies, Inc. |
Glycosylation of peptides via o-linked glycosylation sequences
|
US20100075375A1
(en)
*
|
2006-10-03 |
2010-03-25 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates
|
JP5457185B2
(ja)
*
|
2006-10-04 |
2014-04-02 |
ノヴォ ノルディスク アー/エス |
グリセロール連結のpeg化された糖および糖ペプチド
|
US20080207487A1
(en)
*
|
2006-11-02 |
2008-08-28 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
WO2008074032A1
(en)
|
2006-12-15 |
2008-06-19 |
Baxter International Inc. |
Factor viia- (poly) sialic acid conjugate having prolonged in vivo half-life
|
DK2144923T3
(da)
|
2007-04-03 |
2013-05-13 |
Biogenerix Ag |
Behandlingsfremgangsmåder under anvendelse af glycopegyleret g-csf
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
WO2008151258A2
(en)
*
|
2007-06-04 |
2008-12-11 |
Neose Technologies, Inc. |
O-linked glycosylation using n-acetylglucosaminyl transferases
|
WO2008154639A2
(en)
|
2007-06-12 |
2008-12-18 |
Neose Technologies, Inc. |
Improved process for the production of nucleotide sugars
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
JP5647899B2
(ja)
*
|
2008-01-08 |
2015-01-07 |
ラツィオファルム ゲーエムベーハーratiopharm GmbH |
オリゴサッカリルトランスフェラーゼを使用するポリペプチドの複合糖質化
|
CA2715465C
(en)
|
2008-02-27 |
2017-03-21 |
Novo Nordisk A/S |
Conjugated factor viii molecules
|
PL2459224T3
(pl)
|
2009-07-27 |
2017-08-31 |
Baxalta GmbH |
Koniugaty białka związanego z krzepnięciem krwi
|
US8809501B2
(en)
|
2009-07-27 |
2014-08-19 |
Baxter International Inc. |
Nucleophilic catalysts for oxime linkage
|
NZ597600A
(en)
|
2009-07-27 |
2014-05-30 |
Lipoxen Technologies Ltd |
Glycopolysialylation of non-blood coagulation proteins
|
DK2459224T3
(en)
*
|
2009-07-27 |
2016-07-25 |
Baxalta GmbH |
Blodstørkningsproteinkonjugater
|
US8642737B2
(en)
|
2010-07-26 |
2014-02-04 |
Baxter International Inc. |
Nucleophilic catalysts for oxime linkage
|
HUE049352T2
(hu)
|
2010-12-22 |
2020-09-28 |
Baxalta GmbH |
Anyagok és módszerek egy vízoldható zsírsavszármazéknak egy fehérjéhez való konjugálására
|
KR102617833B1
(ko)
|
2016-05-06 |
2023-12-27 |
엑시큐어 오퍼레이팅 컴퍼니 |
인터류킨 17 수용체 mRNA의 특이적 녹다운을 위한 안티센스 올리고뉴클레오티드 (ASO)를 제시하는 리포좀성 구형 핵산 (SNA) 구축물
|
RU2628882C1
(ru)
*
|
2016-10-24 |
2017-08-22 |
Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) |
Способ стимуляции выработки эритропоэтина клетками костного мозга in vitro
|
US11696954B2
(en)
|
2017-04-28 |
2023-07-11 |
Exicure Operating Company |
Synthesis of spherical nucleic acids using lipophilic moieties
|