PT1131083E - Utilizacao de compostos de libertacao de hormona de crescimento e seus antagonistas para o tratamento de tumores - Google Patents

Utilizacao de compostos de libertacao de hormona de crescimento e seus antagonistas para o tratamento de tumores

Info

Publication number
PT1131083E
PT1131083E PT99955974T PT99955974T PT1131083E PT 1131083 E PT1131083 E PT 1131083E PT 99955974 T PT99955974 T PT 99955974T PT 99955974 T PT99955974 T PT 99955974T PT 1131083 E PT1131083 E PT 1131083E
Authority
PT
Portugal
Prior art keywords
liberation
antagonists
tumors
compounds
treatment
Prior art date
Application number
PT99955974T
Other languages
English (en)
Inventor
Giampiero Muccioli
Mauro Papotti
Ezio Ghigo
Romano Deghenghi
Original Assignee
Ardana Bioscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ardana Bioscience Ltd filed Critical Ardana Bioscience Ltd
Publication of PT1131083E publication Critical patent/PT1131083E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT99955974T 1998-11-16 1999-11-11 Utilizacao de compostos de libertacao de hormona de crescimento e seus antagonistas para o tratamento de tumores PT1131083E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/192,406 US6124263A (en) 1998-11-16 1998-11-16 Treatment of tumors by administration of growth hormone releasing compounds and their antagonists

Publications (1)

Publication Number Publication Date
PT1131083E true PT1131083E (pt) 2004-06-30

Family

ID=22709509

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99955974T PT1131083E (pt) 1998-11-16 1999-11-11 Utilizacao de compostos de libertacao de hormona de crescimento e seus antagonistas para o tratamento de tumores

Country Status (30)

Country Link
US (1) US6124263A (pt)
EP (1) EP1131083B1 (pt)
JP (1) JP2002529512A (pt)
KR (1) KR100704138B1 (pt)
CN (3) CN100368014C (pt)
AR (1) AR021286A1 (pt)
AT (1) ATE258062T1 (pt)
BG (1) BG105572A (pt)
BR (1) BR9915390A (pt)
CA (1) CA2350914A1 (pt)
CO (1) CO5140111A1 (pt)
CZ (1) CZ20011577A3 (pt)
DE (1) DE69914365T2 (pt)
DK (1) DK1131083T3 (pt)
ES (1) ES2212650T3 (pt)
HK (1) HK1040934A1 (pt)
HU (1) HUP0104374A3 (pt)
IL (1) IL142858A0 (pt)
MX (1) MXPA01004689A (pt)
NO (1) NO20012367L (pt)
NZ (1) NZ511280A (pt)
PL (1) PL347659A1 (pt)
PT (1) PT1131083E (pt)
RU (1) RU2240133C2 (pt)
SK (1) SK6352001A3 (pt)
TR (1) TR200101350T2 (pt)
TW (2) TWI237565B (pt)
UA (1) UA73100C2 (pt)
WO (1) WO2000029011A1 (pt)
ZA (1) ZA200103182B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6211156B1 (en) * 1999-11-10 2001-04-03 Asta Medica A.G. Peptides for treatment of erectile dysfunction
CU23157A1 (es) * 2001-01-03 2006-07-18 Ct Ingenieria Genetica Biotech COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL
DE10112882A1 (de) * 2001-03-15 2002-09-19 Max Delbrueck Centrum Verwendung von Tryptophan-Derivaten zur spezifischen zytostatischen Behandlung von Serotonin-produzierenden Tumoren
AU2002254800B2 (en) * 2001-05-10 2006-09-28 Queensland University Of Technology Reproductive cancer diagnosis and therapy
EP1312363A1 (en) * 2001-09-28 2003-05-21 Pfizer Products Inc. Methods of treatment and kits comprising a growth hormone secretagogue
TWI331922B (en) * 2002-08-09 2010-10-21 Ipsen Pharma Sas Growth hormone releasing peptides
WO2005027913A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a growth hormone secretagogue
US20050164952A1 (en) * 2004-01-23 2005-07-28 Vital Pharmaceuticals, Inc. Delivery system for growth hormone releasing peptides
EP2021015A2 (en) * 2006-04-28 2009-02-11 The Administrators Of The Tulane Educational Fund Ghrelin/growth hormone releasing peptide/growth hormone secretatogue receptor antagonists and uses thereof
CN101541341B (zh) 2006-09-27 2013-06-05 益普生制药两合公司 N末端取代的生长素释放肽类似物
JP2010518158A (ja) * 2007-02-13 2010-05-27 ヘルシン セラピューティクス（ユー．エス．），インコーポレイティド 成長ホルモン分泌促進物質を用いた細胞増殖性障害の治療方法
WO2010118309A2 (en) * 2009-04-10 2010-10-14 Board Of Regents, The University Of Texas System Inhibitors of stat3 and uses thereof
US9724381B2 (en) 2009-05-12 2017-08-08 The Administrators Of The Tulane Educational Fund Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof
IT1399610B1 (it) * 2010-01-28 2013-04-26 Univ Milano Bicocca Uso di agonisti e antagonisti dei recettori per i growth hormone secretagogues per la prevenzione e il trattamento di convulsioni ed epilessia
EP3920961A4 (en) 2019-02-08 2022-12-14 United States Government as represented by the Department of Veterans Affairs GROWTH HORMONE RELEASING HORMONE ANTAGONISTS AND THEIR USES
WO2021011874A1 (en) * 2019-07-18 2021-01-21 University Of Miami Ghrh antagonists for use in a method of treating sarcoidosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2053250A1 (en) * 1989-04-26 1990-10-27 David H. Coy Linear somatostatin analogs
IT1240643B (it) * 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
US5385682A (en) * 1990-05-15 1995-01-31 Exxon Research & Engineering Co. Grease composition
SK15096A3 (en) * 1993-08-09 1996-07-03 Biomeasure Inc Therapeutic peptide derivatives and a method of their application
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US5807985A (en) * 1996-06-11 1998-09-15 Deghenghi; Romano Oligopeptide compounds containing D-2-alkyltryptophan capable of promoting the release of growth hormone
US6063796A (en) * 1997-04-04 2000-05-16 Merck & Co., Inc. Somatostatin agonists

Also Published As

Publication number Publication date
ZA200103182B (en) 2001-09-07
CN1895660A (zh) 2007-01-17
ES2212650T3 (es) 2004-07-16
PL347659A1 (en) 2002-04-22
KR100704138B1 (ko) 2007-04-09
SK6352001A3 (en) 2002-09-10
NO20012367D0 (no) 2001-05-14
EP1131083A1 (en) 2001-09-12
KR20010089459A (ko) 2001-10-06
IL142858A0 (en) 2002-03-10
RU2240133C2 (ru) 2004-11-20
CN1200726C (zh) 2005-05-11
CN1594358A (zh) 2005-03-16
DE69914365T2 (de) 2004-11-04
NO20012367L (no) 2001-07-09
NZ511280A (en) 2002-10-25
WO2000029011A1 (en) 2000-05-25
MXPA01004689A (es) 2002-09-18
CN100368014C (zh) 2008-02-13
DE69914365D1 (de) 2004-02-26
CZ20011577A3 (cs) 2002-07-17
CO5140111A1 (es) 2002-03-22
DK1131083T3 (da) 2004-04-26
ATE258062T1 (de) 2004-02-15
BR9915390A (pt) 2001-08-07
JP2002529512A (ja) 2002-09-10
EP1131083B1 (en) 2004-01-21
UA73100C2 (en) 2005-06-15
HUP0104374A3 (en) 2003-03-28
CN1277840C (zh) 2006-10-04
HK1040934A1 (zh) 2002-06-28
AR021286A1 (es) 2002-07-03
TWI263642B (en) 2006-10-11
HUP0104374A2 (hu) 2002-04-29
TR200101350T2 (tr) 2001-11-21
CN1326353A (zh) 2001-12-12
CA2350914A1 (en) 2000-05-25
BG105572A (en) 2002-01-31
TWI237565B (en) 2005-08-11
US6124263A (en) 2000-09-26
TW200530270A (en) 2005-09-16

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