PT1131071E - Composicoes farmaceuticas contendo nicotina dando uma absorcao por via transmucosa rapida - Google Patents

Composicoes farmaceuticas contendo nicotina dando uma absorcao por via transmucosa rapida

Info

Publication number
PT1131071E
PT1131071E PT99972537T PT99972537T PT1131071E PT 1131071 E PT1131071 E PT 1131071E PT 99972537 T PT99972537 T PT 99972537T PT 99972537 T PT99972537 T PT 99972537T PT 1131071 E PT1131071 E PT 1131071E
Authority
PT
Portugal
Prior art keywords
formulations
transmucose
route
fast
nicotine
Prior art date
Application number
PT99972537T
Other languages
English (en)
Inventor
Sven Borje Andersson
Tomas Landh
Stefan Jonn
Stefan Persson
Nils-Olof Lindberg
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of PT1131071E publication Critical patent/PT1131071E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT99972537T 1998-11-23 1999-11-04 Composicoes farmaceuticas contendo nicotina dando uma absorcao por via transmucosa rapida PT1131071E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9803986A SE9803986D0 (sv) 1998-11-23 1998-11-23 New compositions

Publications (1)

Publication Number Publication Date
PT1131071E true PT1131071E (pt) 2004-06-30

Family

ID=20413363

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99972537T PT1131071E (pt) 1998-11-23 1999-11-04 Composicoes farmaceuticas contendo nicotina dando uma absorcao por via transmucosa rapida

Country Status (12)

Country Link
US (1) US6676959B1 (pt)
EP (1) EP1131071B1 (pt)
JP (1) JP2002530335A (pt)
AT (1) ATE264102T1 (pt)
AU (1) AU1434000A (pt)
DE (1) DE69916486T2 (pt)
DK (1) DK1131071T3 (pt)
ES (1) ES2220149T3 (pt)
HK (1) HK1040614B (pt)
PT (1) PT1131071E (pt)
SE (1) SE9803986D0 (pt)
WO (1) WO2000030641A1 (pt)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0103211D0 (sv) * 2001-09-27 2001-09-27 Pharmacia Ab New formulations and use thereof
SE0103210D0 (sv) * 2001-09-27 2001-09-27 Pharmacia Ab New formulations and use thereof
US20030087937A1 (en) * 2001-10-15 2003-05-08 Nils-Olof Lindberg Nicotine and cocoa powder compositions
SE0202365D0 (sv) 2002-08-05 2002-08-05 Pharmacia Ab New formulation and use thereof
DE10251963A1 (de) * 2002-11-08 2004-05-19 Lts Lohmann Therapie-Systeme Ag Transmucosale pharmazeutische Darreichungsform
US9358296B2 (en) * 2003-02-24 2016-06-07 Pharmaceutical Productions Inc. Transmucosal drug delivery system
SE0300831D0 (sv) * 2003-03-26 2003-03-26 Pharmacia Ab New formulations and use therof
SE0300830D0 (sv) * 2003-03-26 2003-03-26 Pharmacia Ab New formulations and use thereof
US8627828B2 (en) * 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
EP1691631A4 (en) 2003-11-07 2012-09-05 Us Smokeless Tobacco Co TOBACCO COMPOSITIONS
FR2882656B1 (fr) * 2005-03-07 2007-06-22 Schwartz Laboratoires Robert S Composition antitabagique
US20070134169A1 (en) * 2005-12-11 2007-06-14 Rabinoff Michael D Methods for smoking cessation or alcohol cessation or other addiction cessation
US7946296B2 (en) * 2006-05-26 2011-05-24 Philip Morris Usa Inc. Dissolvable tobacco film strips and method of making the same
PL2450446T3 (pl) * 2006-09-13 2015-10-30 22Nd Century Ltd Llc Zwiększanie poziomów alkaloidów nikotynowych
US20080131508A1 (en) * 2006-12-01 2008-06-05 Cephalon, Inc Oral transmucosal nicotine dosage form
US20100028447A1 (en) 2007-01-22 2010-02-04 Targacept, Inc. Intranasal, Buccal, And Sublingual Administration Of Metanicotine Analogs
AU2008215771A1 (en) * 2007-02-15 2008-08-21 Derma-Young Ltd. Compositions and methods for enhancing transmucosal delivery
US8356606B2 (en) * 2007-06-01 2013-01-22 Philip Morris Usa Inc. Production of micronized encapsulated tobacco particles for tobacco flavor delivery from an oral pouch
US9167835B2 (en) 2008-12-30 2015-10-27 Philip Morris Usa Inc. Dissolvable films impregnated with encapsulated tobacco, tea, coffee, botanicals, and flavors for oral products
US9167847B2 (en) * 2009-03-16 2015-10-27 Philip Morris Usa Inc. Production of coated tobacco particles suitable for usage in a smokeless tobacoo product
US10327467B2 (en) 2010-04-14 2019-06-25 Altria Client Services Llc Preformed smokeless tobacco product
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9763928B2 (en) * 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US9044035B2 (en) 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
US10799548B2 (en) * 2013-03-15 2020-10-13 Altria Client Services Llc Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products
US11503853B2 (en) 2013-09-09 2022-11-22 R.J. Reynolds Tobacco Company Smokeless tobacco composition incorporating a botanical material
US10357054B2 (en) 2013-10-16 2019-07-23 R.J. Reynolds Tobacco Company Smokeless tobacco pastille
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
CN113754634A (zh) 2014-05-27 2021-12-07 R.J.雷诺兹烟草公司 烟碱盐、共晶体和盐共晶体络合物
US10881133B2 (en) 2015-04-16 2021-01-05 R.J. Reynolds Tobacco Company Tobacco-derived cellulosic sugar
US10869497B2 (en) 2015-09-08 2020-12-22 R.J. Reynolds Tobacco Company High-pressure cold pasteurization of tobacco material
WO2017089931A1 (en) 2015-11-25 2017-06-01 R. J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US10499684B2 (en) 2016-01-28 2019-12-10 R.J. Reynolds Tobacco Company Tobacco-derived flavorants
US11154087B2 (en) 2016-02-02 2021-10-26 R.J. Reynolds Tobacco Company Method for preparing flavorful compounds isolated from black liquor and products incorporating the flavorful compounds
US11091446B2 (en) 2017-03-24 2021-08-17 R.J. Reynolds Tobacco Company Methods of selectively forming substituted pyrazines
WO2019049049A1 (en) 2017-09-05 2019-03-14 R. J. Reynolds Tobacco Company SALTS, CO-CRYSTALS, AND CO-CRYSTAL COMPLEXES OF NICOTINE SALTS
US20190307082A1 (en) 2018-04-05 2019-10-10 R.J. Reynolds Tobacco Company Oriental tobacco production methods
BR112020025604A2 (pt) 2018-06-15 2021-03-23 R.J. Reynolds Tobacco Company purificação de nicotina
WO2021116865A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Agents for oral composition
WO2021116855A1 (en) 2019-12-09 2021-06-17 Nicoventures Trading Limited Oral compositions and methods of manufacture
EP4304568A1 (en) 2021-03-09 2024-01-17 Nicoventures Trading Limited Oral products and methods of manufacture
US20220354785A1 (en) 2021-04-22 2022-11-10 Nicoventures Trading Limited Oral lozenge products
JP2024519718A (ja) 2021-05-06 2024-05-21 ニコベンチャーズ トレーディング リミテッド 喉の刺激を減少させるための口腔用組成物及び関連する方法
WO2023053062A1 (en) 2021-09-30 2023-04-06 Nicoventures Trading Limited Oral product with a basic amine and an ion pairing agent
WO2023084499A1 (en) 2021-11-15 2023-05-19 Nicoventures Trading Limited Products with enhanced sensory characteristics
WO2023248187A1 (en) 2022-06-24 2023-12-28 Nicoventures Trading Limited Oral composition comprising a receptor modulator
GB202214771D0 (en) 2022-10-07 2022-11-23 Nicoventures Trading Ltd Oral product
WO2024074842A1 (en) 2022-10-07 2024-04-11 Nicoventures Trading Limited Oral product
WO2024074843A1 (en) 2022-10-07 2024-04-11 Nicoventures Trading Limited Oral product
GB202214775D0 (en) 2022-10-07 2022-11-23 Nicoventures Trading Ltd Oral product
WO2024074839A1 (en) 2022-10-07 2024-04-11 Nicoventures Trading Limited Oral product
GB202214803D0 (en) 2022-10-07 2022-11-23 Nicoventures Trading Ltd Oral product
WO2024095163A1 (en) 2022-11-01 2024-05-10 Nicoventures Trading Limited Oral composition comprising encapsulated ph adjusting agent
GB202216465D0 (en) 2022-11-04 2022-12-21 Nicoventures Trading Ltd Oral product
WO2024095011A1 (en) 2022-11-04 2024-05-10 Nicoventures Trading Limited Oral product

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783207A (en) * 1985-05-01 1998-07-21 University Of Utah Research Foundation Selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine
JPS62175141A (ja) * 1986-01-29 1987-07-31 Kazuo Takatsu 複合チヨコレ−ト
US5017400A (en) * 1988-06-10 1991-05-21 Suomen Xyrofin Oy Non-cariogenic sweetener
US5004601A (en) * 1988-10-14 1991-04-02 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
US5098730A (en) * 1988-11-14 1992-03-24 Cultor Ltd. Dietetic sweetening composition
US5512306A (en) 1992-06-19 1996-04-30 Pharmica Ab Smoking substitute
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
JPH0940564A (ja) * 1995-07-26 1997-02-10 Taiyo Kagaku Co Ltd 悪酔予防改善用組成物
JPH0956333A (ja) * 1995-08-21 1997-03-04 Kozaburo Shiba 機能性梅チョコレート
JP2001518520A (ja) * 1997-10-03 2001-10-16 キャリー メディカル コーポレイション ニコチンレセプターアンタゴニストおよび抗抑うつ薬または抗不安薬を含有するニコチン嗜癖を治療する組成物

Also Published As

Publication number Publication date
HK1040614B (zh) 2004-10-08
EP1131071A1 (en) 2001-09-12
DK1131071T3 (da) 2004-05-10
HK1040614A1 (en) 2002-06-21
ATE264102T1 (de) 2004-04-15
EP1131071B1 (en) 2004-04-14
JP2002530335A (ja) 2002-09-17
AU1434000A (en) 2000-06-13
ES2220149T3 (es) 2004-12-01
DE69916486D1 (de) 2004-05-19
DE69916486T2 (de) 2004-08-26
WO2000030641A1 (en) 2000-06-02
US6676959B1 (en) 2004-01-13
SE9803986D0 (sv) 1998-11-23

Similar Documents

Publication Publication Date Title
PT1131071E (pt) Composicoes farmaceuticas contendo nicotina dando uma absorcao por via transmucosa rapida
EE200300033A (et) Tsüklopentanoindoolid, nende kasutamine ravimi valmistamiseks ning neid sisaldav farmatseutiline kompositsioon
IS8726A (is) Meðferðarfræðilegar samsetningar þrýstingslækkandi efna og efna sem hamla gegn æðamyndun
TR200002855T2 (tr) Raloksifenin solunum yolu ile veya burundan uygulanması.
MXPA06000381A (es) Composicion de dulce dental antiplaca y que puede ser masticada.
NO20062504L (no) Sammensetninger og doseringsformer for forbedret absorpsjon
DE60233967D1 (de) Verbesserte essbare filmformulierungen mit maltodextrin
AP1424A (en) 2-Phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole in combination with estrogens.
BR0109672A (pt) Uso de zd6126 ou de um seu sal farmaceuticamente aceitável e um de: um agente antitumoral de plantina e um taxano, composição farmacêutica, produto de combinação, kit, e, método para a produção de um efeito de danificação vascular em um animal de sangue quente
BRPI0008228B8 (pt) composição farmacêutica contendo n-benzoil estaurosporina e agentes solubilizantes
HUP0203844A2 (hu) Növekedési hormon kibocsátó tulajdonságú vegyület, ezt tartalmazó gyógyszerkészítmény és alkalmazása
ES2168457T3 (es) Composiciones farmaceuticas que comprenden una superoxido dismutasa.
PT1051159E (pt) Composicoes farmaceuticas solidas contendo miltefosina para administracao oral no tratamento de leishmaniose
DK0764023T3 (da) Forbindelser og præparater til administrering via oral inhalation eller insufflation
BR0212834A (pt) Formulações e uso das mesmas
DE60016567D1 (de) Makrophagenhaltige zusammensetzung mit antiinfektiösen und hematopoietischen eigenschaften sowie deren herstellungsmethode
DE69815277D1 (de) Nimelulide enthaltendes pharmazeutisches präparat zur oralen verabreichung
DK1061938T3 (da) Orale sammensætninger med cytotoksiske proteiner i lav dosis
ATE399544T1 (de) Synergistische zusammensetzung enthaltend roflumilast und (r,r)-formoterol
ATE194498T1 (de) Wasserfreies mittel auf lactulosebasis
SE9803158D0 (sv) A new composition
WO2002051404A8 (fr) Compositions orales
ES2165734T3 (es) Composiciones basadas en pentoxifilina y anticitoquina.
DE69938347D1 (de) Medikamentöse verabreichung von nikotin in form von kaugummi
ATE284685T1 (de) Stabile pharmazeutische nimesulidverbindungen