PT1094834E - Composicao farmaceutica para o tratamento de dispepsia funcional e/ou da sindroma do intestino irritavel e nova utilizacao de substancias contidas nessa composicao - Google Patents
Composicao farmaceutica para o tratamento de dispepsia funcional e/ou da sindroma do intestino irritavel e nova utilizacao de substancias contidas nessa composicaoInfo
- Publication number
- PT1094834E PT1094834E PT99930089T PT99930089T PT1094834E PT 1094834 E PT1094834 E PT 1094834E PT 99930089 T PT99930089 T PT 99930089T PT 99930089 T PT99930089 T PT 99930089T PT 1094834 E PT1094834 E PT 1094834E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- composition
- pharmaceutical composition
- functional
- irritavel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9802080A SE9802080D0 (sv) | 1998-06-11 | 1998-06-11 | Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1094834E true PT1094834E (pt) | 2004-03-31 |
Family
ID=20411665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99930089T PT1094834E (pt) | 1998-06-11 | 1999-06-08 | Composicao farmaceutica para o tratamento de dispepsia funcional e/ou da sindroma do intestino irritavel e nova utilizacao de substancias contidas nessa composicao |
Country Status (19)
Country | Link |
---|---|
US (1) | US6348447B1 (pt) |
EP (2) | EP1405642A1 (pt) |
JP (2) | JP2002517468A (pt) |
AT (1) | ATE252912T1 (pt) |
AU (1) | AU738994B2 (pt) |
CA (1) | CA2321700C (pt) |
CZ (1) | CZ300873B6 (pt) |
DE (1) | DE69912434T2 (pt) |
DK (1) | DK1094834T3 (pt) |
ES (1) | ES2205845T3 (pt) |
HU (1) | HUP0103147A3 (pt) |
NO (1) | NO327738B1 (pt) |
NZ (1) | NZ506163A (pt) |
PL (1) | PL198802B1 (pt) |
PT (1) | PT1094834E (pt) |
RU (1) | RU2226402C2 (pt) |
SE (1) | SE9802080D0 (pt) |
WO (1) | WO1999064060A1 (pt) |
ZA (1) | ZA200004080B (pt) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE545652T1 (de) | 1999-06-29 | 2012-03-15 | Mannkind Corp | Reinigung und stabilisierung von proteinen und peptiden in pharmaceutischen agentien |
US9006175B2 (en) * | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US6528486B1 (en) | 1999-07-12 | 2003-03-04 | Zealand Pharma A/S | Peptide agonists of GLP-1 activity |
MXPA02009031A (es) | 2000-03-14 | 2004-08-19 | Amylin Pharmaceuticals Inc | Efectos del peptido-1(7-36) tipo glucagon en la motilidad antro-piloro.duodenal. |
EP1282436B1 (en) * | 2000-05-19 | 2008-06-11 | Amylin Pharmaceuticals, Inc. | Treatment of acute coronary syndrome with glp-1 |
DK1463751T3 (da) | 2001-12-21 | 2013-08-26 | Human Genome Sciences Inc | Albuminfusionsproteiner. |
ES2614603T3 (es) | 2002-02-20 | 2017-06-01 | Emisphere Technologies, Inc. | Procedimiento de administración de moléculas GLP-1 |
ES2300568T3 (es) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | Aparato de inhalacion. |
US20080260838A1 (en) * | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
EA008831B1 (ru) | 2003-06-12 | 2007-08-31 | Эли Лилли Энд Компани | Слитые белки аналогов glp-1 |
DK1633774T3 (da) * | 2003-06-18 | 2010-05-25 | Tranzyme Pharma Inc | Makrocykliske motilinreceptorantagonister |
US20060286129A1 (en) | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
JP2008536881A (ja) * | 2005-04-21 | 2008-09-11 | ガストロテック・ファルマ・アクティーゼルスカブ | Glp−1分子と制吐剤との医薬製剤 |
AU2006247734B2 (en) | 2005-05-13 | 2011-06-23 | Eli Lilly And Company | GLP-1 pegylated compounds |
US8236759B2 (en) | 2005-06-30 | 2012-08-07 | Ipsen Pharma Sas | GLP-1 pharmaceutical compositions |
ES2532666T3 (es) * | 2005-07-29 | 2015-03-30 | Solasia Pharma K.K. | Compuestos y métodos para el tratamiento del cáncer |
CN104324362B (zh) | 2005-09-14 | 2018-04-24 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
MX2008010721A (es) | 2006-02-22 | 2008-09-01 | Mannkind Corp | Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo. |
RU2445972C2 (ru) * | 2006-12-29 | 2012-03-27 | Ипсен Фарма С.А.С. | Фармацевтические композиции glp-1 |
US8236760B2 (en) * | 2007-04-27 | 2012-08-07 | Cedars-Sinsai Medical Center | Use of GLP-1 receptor agonists for the treatment of short bowel syndrome |
KR101736535B1 (ko) * | 2007-10-24 | 2017-05-16 | 맨카인드 코포레이션 | Glp-1에 의한 유해 효과의 예방 방법 |
US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
RU2467741C2 (ru) * | 2007-10-24 | 2012-11-27 | Маннкайнд Корпорейшн | Доставка активных веществ |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
US8424518B2 (en) | 2008-06-13 | 2013-04-23 | Mannkind Corporation | Dry powder inhaler and system for drug delivery |
AU2009261441B2 (en) | 2008-06-17 | 2013-01-10 | Glytech, Inc. | Oligosaccharide chain added glp-1 peptide |
EP2609954B1 (en) | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
EP2216042A1 (en) | 2009-02-09 | 2010-08-11 | Ipsen Pharma S.A.S. | GLP-1 analogues pharmaceutical compositions |
JP5667095B2 (ja) | 2009-03-11 | 2015-02-12 | マンカインド コーポレイション | 吸入器の抵抗を測定するための装置、システムおよび方法 |
US8614185B2 (en) | 2009-05-04 | 2013-12-24 | Centocor Ortho Biotech Inc. | Fusion proteins of alpha-MSH derivatives and Fc |
JP5751641B2 (ja) | 2009-05-06 | 2015-07-22 | ヤンセン バイオテツク,インコーポレーテツド | メラノコルチン受容体結合コンジュゲート |
KR20180036807A (ko) | 2009-06-12 | 2018-04-09 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
RU2540012C2 (ru) * | 2009-07-29 | 2015-01-27 | Дайити Санкио Компани, Лимитед | Мотилин-подобное пептидное соединение, обладающее приданной ему трансмукозальной абсорбционной способностью |
US20120264684A1 (en) | 2009-10-30 | 2012-10-18 | Yasuhiro Kajihara | Glycosylated Form of Antigenic GLP-1 Analogue |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
WO2011123943A1 (en) | 2010-04-09 | 2011-10-13 | Mount Sinai Hospital | Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist |
NZ603169A (en) | 2010-04-27 | 2015-02-27 | Zealand Pharma As | Peptide conjugates of glp-1 receptor agonists and gastrin and their use |
CA2801936C (en) | 2010-06-21 | 2021-06-01 | Mannkind Corporation | Dry powder drug delivery system and methods |
AU2011274229A1 (en) | 2010-07-02 | 2013-01-10 | Angiochem Inc. | Short and D-amino acid-containing polypeptides for therapeutic conjugates and uses thereof |
RU2600440C3 (ru) | 2010-12-16 | 2021-12-10 | Ново Нордиск А/С | Твердые композиции, содержащие агонист glp-1 и соль n-(8-(2-гидроксибензоил)амино)каприловой кислоты |
CN103826988B (zh) | 2011-04-01 | 2016-03-09 | 曼金德公司 | 用于药物药盒的泡罩包装 |
MY161450A (en) | 2011-04-12 | 2017-04-14 | Novo Nordisk As | Double-acylated glp-1 derivatives |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
AU2012328885B2 (en) | 2011-10-24 | 2017-08-31 | Mannkind Corporation | Methods and compositions for treating pain |
CA2853884A1 (en) | 2011-11-03 | 2013-05-10 | Zealand Pharma A/S | Glp-1 receptor agonist peptide gastrin conjugates |
DK2827845T3 (en) | 2012-03-22 | 2019-04-01 | Novo Nordisk As | COMPOSITIONS INCLUDING A PROCEDURE AND PREPARING THEREOF |
RS64942B1 (sr) | 2012-03-22 | 2024-01-31 | Novo Nordisk As | Kompozicije koje obuhvataju sredstvo za isporuku i njihova priprema |
RS57727B1 (sr) | 2012-03-22 | 2018-12-31 | Novo Nordisk As | Kompozicije glp-1 peptida i njihovo dobijanje |
ES2871328T3 (es) | 2012-06-20 | 2021-10-28 | Novo Nordisk As | Formulación de comprimido que comprende un péptido y un agente de suministro |
AU2013289957B2 (en) | 2012-07-12 | 2017-02-23 | Mannkind Corporation | Dry powder drug delivery systems and methods |
MY170671A (en) | 2012-07-23 | 2019-08-26 | Zealand Pharma As | Glucagon analogues |
TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
CA2906817C (en) | 2013-03-15 | 2022-01-18 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
MX2016000739A (es) | 2013-07-18 | 2017-04-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
CN104371019B (zh) | 2013-08-13 | 2019-09-10 | 鸿运华宁(杭州)生物医药有限公司 | 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质 |
HUE039616T2 (hu) | 2013-10-17 | 2019-01-28 | Zealand Pharma As | Acilezett glükagon analógok |
US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
BR112016009995B1 (pt) | 2013-11-06 | 2023-04-18 | Zealand Pharma A/S | Compostos agonistas triplos glucagon-glp-1-gip |
AU2014345569B2 (en) | 2013-11-06 | 2020-08-13 | Zealand Pharma A/S | GIP-GLP-1 dual agonist compounds and methods |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
CA2965732A1 (en) | 2014-10-29 | 2016-05-06 | Zealand Pharma A/S | Gip agonist compounds and methods |
KR101825048B1 (ko) | 2014-12-31 | 2018-02-05 | 주식회사 제넥신 | GLP 및 면역글로불린 하이브리드 Fc 융합 폴리펩타이드 및 이의 용도 |
CA2975633A1 (en) | 2015-02-11 | 2016-08-18 | Gmax Biopharm Llc. | Stable pharmaceutical solution formulation of glp-1r antibody fusion protein |
KR20170137198A (ko) | 2015-04-16 | 2017-12-12 | 질랜드 파마 에이/에스 | 아실화된 글루카곤 유사체 |
CN117384274A (zh) | 2016-12-09 | 2024-01-12 | 西兰制药公司 | 酰化的glp-1/glp-2双重激动剂 |
BR112020014624A2 (pt) | 2018-02-02 | 2020-12-08 | Novo Nordisk A/S | Composições sólidas compreendendo agonista de glp-1, sal de ácido n-(8-(2-hidroxibenzoil) amino)caprílico e lubrificante |
CN117126279A (zh) | 2018-03-20 | 2023-11-28 | 鸿运华宁(杭州)生物医药有限公司 | Gipr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用 |
CN112521501A (zh) | 2019-09-18 | 2021-03-19 | 鸿运华宁(杭州)生物医药有限公司 | Gipr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY147327A (en) * | 1995-06-29 | 2012-11-30 | Novartis Ag | Somatostatin peptides |
US5994500A (en) * | 1996-07-19 | 1999-11-30 | 1149336 Ontario Inc. | Antagonists of intestinotrophic GLP-2 peptides |
-
1998
- 1998-06-11 SE SE9802080A patent/SE9802080D0/xx unknown
-
1999
- 1999-06-08 PL PL343104A patent/PL198802B1/pl not_active IP Right Cessation
- 1999-06-08 EP EP20030024624 patent/EP1405642A1/en not_active Withdrawn
- 1999-06-08 DK DK99930089T patent/DK1094834T3/da active
- 1999-06-08 JP JP2000553128A patent/JP2002517468A/ja not_active Ceased
- 1999-06-08 AT AT99930089T patent/ATE252912T1/de not_active IP Right Cessation
- 1999-06-08 DE DE69912434T patent/DE69912434T2/de not_active Expired - Lifetime
- 1999-06-08 RU RU2000133249/14A patent/RU2226402C2/ru not_active IP Right Cessation
- 1999-06-08 ES ES99930089T patent/ES2205845T3/es not_active Expired - Lifetime
- 1999-06-08 AU AU46697/99A patent/AU738994B2/en not_active Ceased
- 1999-06-08 NZ NZ506163A patent/NZ506163A/en unknown
- 1999-06-08 US US09/445,571 patent/US6348447B1/en not_active Expired - Lifetime
- 1999-06-08 PT PT99930089T patent/PT1094834E/pt unknown
- 1999-06-08 WO PCT/SE1999/000997 patent/WO1999064060A1/en active IP Right Grant
- 1999-06-08 HU HU0103147A patent/HUP0103147A3/hu unknown
- 1999-06-08 EP EP99930089A patent/EP1094834B1/en not_active Expired - Lifetime
- 1999-06-08 CZ CZ20004491A patent/CZ300873B6/cs not_active IP Right Cessation
- 1999-06-08 CA CA2321700A patent/CA2321700C/en not_active Expired - Fee Related
-
2000
- 2000-08-10 ZA ZA200004080A patent/ZA200004080B/xx unknown
- 2000-12-06 NO NO20006194A patent/NO327738B1/no not_active IP Right Cessation
-
2010
- 2010-07-01 JP JP2010151403A patent/JP2010270125A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NZ506163A (en) | 2004-10-29 |
US6348447B1 (en) | 2002-02-19 |
PL343104A1 (en) | 2001-07-30 |
HUP0103147A3 (en) | 2002-02-28 |
CZ300873B6 (cs) | 2009-09-02 |
DE69912434T2 (de) | 2004-05-06 |
NO20006194D0 (no) | 2000-12-06 |
CA2321700A1 (en) | 1999-12-16 |
NO327738B1 (no) | 2009-09-14 |
ATE252912T1 (de) | 2003-11-15 |
WO1999064060A1 (en) | 1999-12-16 |
HUP0103147A2 (hu) | 2002-01-28 |
AU738994B2 (en) | 2001-10-04 |
EP1405642A1 (en) | 2004-04-07 |
PL198802B1 (pl) | 2008-07-31 |
JP2010270125A (ja) | 2010-12-02 |
SE9802080D0 (sv) | 1998-06-11 |
CA2321700C (en) | 2011-05-03 |
CZ20004491A3 (en) | 2001-05-16 |
DE69912434D1 (de) | 2003-12-04 |
ZA200004080B (en) | 2001-12-24 |
AU4669799A (en) | 1999-12-30 |
JP2002517468A (ja) | 2002-06-18 |
RU2226402C2 (ru) | 2004-04-10 |
EP1094834A1 (en) | 2001-05-02 |
DK1094834T3 (da) | 2004-01-05 |
ES2205845T3 (es) | 2004-05-01 |
NO20006194L (no) | 2001-01-25 |
EP1094834B1 (en) | 2003-10-29 |
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