DK1094834T3 - Farmaceutisk sammensætning til behandling af funktionel dybspepsi og/eller irritabel tarmsyndrom samt ny anvendelse deraf - Google Patents
Farmaceutisk sammensætning til behandling af funktionel dybspepsi og/eller irritabel tarmsyndrom samt ny anvendelse derafInfo
- Publication number
- DK1094834T3 DK1094834T3 DK99930089T DK99930089T DK1094834T3 DK 1094834 T3 DK1094834 T3 DK 1094834T3 DK 99930089 T DK99930089 T DK 99930089T DK 99930089 T DK99930089 T DK 99930089T DK 1094834 T3 DK1094834 T3 DK 1094834T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- bowel syndrome
- irritable bowel
- pharmaceutical composition
- sepsis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9802080A SE9802080D0 (sv) | 1998-06-11 | 1998-06-11 | Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein |
PCT/SE1999/000997 WO1999064060A1 (en) | 1998-06-11 | 1999-06-08 | Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1094834T3 true DK1094834T3 (da) | 2004-01-05 |
Family
ID=20411665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99930089T DK1094834T3 (da) | 1998-06-11 | 1999-06-08 | Farmaceutisk sammensætning til behandling af funktionel dybspepsi og/eller irritabel tarmsyndrom samt ny anvendelse deraf |
Country Status (19)
Country | Link |
---|---|
US (1) | US6348447B1 (da) |
EP (2) | EP1405642A1 (da) |
JP (2) | JP2002517468A (da) |
AT (1) | ATE252912T1 (da) |
AU (1) | AU738994B2 (da) |
CA (1) | CA2321700C (da) |
CZ (1) | CZ300873B6 (da) |
DE (1) | DE69912434T2 (da) |
DK (1) | DK1094834T3 (da) |
ES (1) | ES2205845T3 (da) |
HU (1) | HUP0103147A3 (da) |
NO (1) | NO327738B1 (da) |
NZ (1) | NZ506163A (da) |
PL (1) | PL198802B1 (da) |
PT (1) | PT1094834E (da) |
RU (1) | RU2226402C2 (da) |
SE (1) | SE9802080D0 (da) |
WO (1) | WO1999064060A1 (da) |
ZA (1) | ZA200004080B (da) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
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US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
EP2280004B1 (en) | 1999-06-29 | 2016-04-20 | MannKind Corporation | Pharmaceutical formulations comprising insulin complexed with a diketopiperazine |
US6528486B1 (en) | 1999-07-12 | 2003-03-04 | Zealand Pharma A/S | Peptide agonists of GLP-1 activity |
EP1267912A2 (en) | 2000-03-14 | 2003-01-02 | Burkhard Göke | Effects of glucagon-like peptide-1 (7-36) on antro-pyloro-duodenal motility |
DE60134403D1 (de) * | 2000-05-19 | 2008-07-24 | Amylin Pharmaceuticals Inc | Behandlung des akuten koronaren syndroms mit glp-1 |
ES2545090T3 (es) | 2001-12-21 | 2015-09-08 | Human Genome Sciences, Inc. | Proteínas de fusión de albúmina y GCSF |
WO2003072195A2 (en) | 2002-02-20 | 2003-09-04 | Eli Lilly And Company | Method for administering glp-1 molecules |
US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
US20080260838A1 (en) * | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
EP2368909A1 (en) | 2003-06-12 | 2011-09-28 | Eli Lilly and Company | GLP-1 analog fusion proteins |
EP2210612B1 (en) | 2003-06-18 | 2016-10-05 | Ocera Therapeutics, Inc. | Macrocyclic antagonists of the motilin receptor |
US20060286129A1 (en) | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
KR101273120B1 (ko) | 2004-08-20 | 2013-06-13 | 맨카인드 코포레이션 | 다이케토피페라진 합성의 촉매 작용 |
DK1791542T3 (da) | 2004-08-23 | 2015-06-15 | Mannkind Corp | Diketopiperazinsalte til lægemiddel-levering |
WO2006111169A1 (en) * | 2005-04-21 | 2006-10-26 | Gastrotech Pharma A/S | Pharmaceutical preparations of a glp-1 molecule and an anti-emetic drug |
BRPI0609676A2 (pt) | 2005-05-13 | 2011-10-18 | Lilly Co Eli | composto de glp-1 peguilado,e, uso do mesmo |
CN101258163B (zh) | 2005-06-30 | 2013-08-21 | 益普生制药股份有限公司 | Glp-1药物组合物 |
ES2531159T3 (es) * | 2005-07-29 | 2015-03-11 | Solasia Pharma K K | Compuestos y métodos para el tratamiento del cáncer |
RU2390325C2 (ru) | 2005-09-14 | 2010-05-27 | Маннкайнд Корпорейшн | Способ приготовления лекарственного препарата, основанный на увеличении сродства активных агентов к поверхностям кристаллических микрочастиц |
KR20080096809A (ko) | 2006-02-22 | 2008-11-03 | 맨카인드 코포레이션 | 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법 |
US20100137204A1 (en) * | 2006-12-29 | 2010-06-03 | Zheng Xin Dong | Glp-1 pharmaceutical compositions |
US8236760B2 (en) * | 2007-04-27 | 2012-08-07 | Cedars-Sinsai Medical Center | Use of GLP-1 receptor agonists for the treatment of short bowel syndrome |
US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
BRPI0818874A2 (pt) * | 2007-10-24 | 2015-05-05 | Mannkind Corp | Liberação de agentes ativos |
CA2703338A1 (en) * | 2007-10-24 | 2009-04-30 | Mannkind Corporation | Method of preventing adverse effects by glp-1 |
ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
CA2727147A1 (en) | 2008-06-17 | 2009-12-23 | Otsuka Chemical Co., Ltd. | Glycosylated glp-1 peptide |
US9364619B2 (en) | 2008-06-20 | 2016-06-14 | Mannkind Corporation | Interactive apparatus and method for real-time profiling of inhalation efforts |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
EP2216042A1 (en) | 2009-02-09 | 2010-08-11 | Ipsen Pharma S.A.S. | GLP-1 analogues pharmaceutical compositions |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
US8614185B2 (en) | 2009-05-04 | 2013-12-24 | Centocor Ortho Biotech Inc. | Fusion proteins of alpha-MSH derivatives and Fc |
EP2427204B1 (en) | 2009-05-06 | 2017-04-05 | Janssen Biotech, Inc. | Melanocortin receptor binding conjugates |
KR20200028501A (ko) | 2009-06-12 | 2020-03-16 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
WO2011013728A1 (ja) * | 2009-07-29 | 2011-02-03 | 第一三共株式会社 | 経粘膜吸収性を付与したモチリン類似ペプチド化合物 |
RU2012122162A (ru) | 2009-10-30 | 2013-12-10 | Глитек,Инк. | Гликолизированная форма аналога антигенного glp-1 |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
EP2555791B1 (en) | 2010-04-09 | 2017-11-01 | Sinai Health System | Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist |
CN103003300B (zh) | 2010-04-27 | 2017-06-09 | 西兰制药公司 | Glp‑1受体激动剂和胃泌素的肽缀合物及其用途 |
RU2571331C1 (ru) | 2010-06-21 | 2015-12-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
AU2011274229A1 (en) | 2010-07-02 | 2013-01-10 | Angiochem Inc. | Short and D-amino acid-containing polypeptides for therapeutic conjugates and uses thereof |
PT2651398T (pt) | 2010-12-16 | 2018-03-09 | Novo Nordisk As | Composições sólidas compreendendo um agonista de glp-1 e um sal de ácido n-(8-(2-hidroxibenzoil)amino) caprílico |
EP2694402B1 (en) | 2011-04-01 | 2017-03-22 | MannKind Corporation | Blister package for pharmaceutical cartridges |
EP3225631B1 (en) | 2011-04-12 | 2019-01-09 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
CA2852536A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
US9259477B2 (en) | 2011-11-03 | 2016-02-16 | Zealand Pharma A/S | GLP-1 receptor agonist peptide gastrin conjugates |
PT2827845T (pt) | 2012-03-22 | 2019-03-29 | Novo Nordisk As | Composições compreendendo um agente de entrega e sua preparação |
EP2827885B1 (en) | 2012-03-22 | 2018-08-15 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
CN104203221A (zh) | 2012-03-22 | 2014-12-10 | 诺和诺德A/S(股份有限公司) | 包含递送剂的组合物及其制备 |
WO2013189988A1 (en) | 2012-06-20 | 2013-12-27 | Novo Nordisk A/S | Tablet formulation comprising a peptide and a delivery agent |
JP6312262B2 (ja) | 2012-07-12 | 2018-04-18 | マンカインド コーポレイション | 乾燥粉末薬物送達システム |
DK2875043T3 (da) | 2012-07-23 | 2017-03-27 | Zealand Pharma As | Glucagonanaloger |
TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
BR112016000937A8 (pt) | 2013-07-18 | 2021-06-22 | Mannkind Corp | formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco |
JP2016530930A (ja) | 2013-08-05 | 2016-10-06 | マンカインド コーポレイション | 通気装置及び方法 |
CN104371019B (zh) | 2013-08-13 | 2019-09-10 | 鸿运华宁(杭州)生物医药有限公司 | 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质 |
DK3057984T3 (da) | 2013-10-17 | 2018-10-08 | Zealand Pharma As | Acylerede glucagon-analoger |
US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
JP6682432B2 (ja) | 2013-11-06 | 2020-04-15 | ジーランド ファーマ アクティーゼルスカブ | Gip−glp−1デュアルアゴニスト化合物及び方法 |
CN105829339B (zh) | 2013-11-06 | 2021-03-12 | 西兰制药公司 | 胰高血糖素-glp-1-gip三重激动剂化合物 |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
EP3212218B1 (en) | 2014-10-29 | 2021-06-30 | Zealand Pharma A/S | Gip agonist compounds and methods |
KR101825048B1 (ko) | 2014-12-31 | 2018-02-05 | 주식회사 제넥신 | GLP 및 면역글로불린 하이브리드 Fc 융합 폴리펩타이드 및 이의 용도 |
ES2833099T3 (es) | 2015-02-11 | 2021-06-14 | Gmax Biopharm Llc | Preparación de disolución estabilizada de una proteína de fusión de un anticuerpo de GLP-1R farmacéutica |
CA2980978A1 (en) | 2015-04-16 | 2016-10-20 | Zealand Pharma A/S | Acylated glucagon analogue |
RU2753193C2 (ru) | 2016-12-09 | 2021-08-12 | Зилэнд Фарма А/С | Ацилированные двойные агонисты glp-1/glp-2 |
SG11202006595RA (en) | 2018-02-02 | 2020-08-28 | Novo Nordisk As | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
CN117126279A (zh) | 2018-03-20 | 2023-11-28 | 鸿运华宁(杭州)生物医药有限公司 | Gipr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用 |
CN112521501A (zh) | 2019-09-18 | 2021-03-19 | 鸿运华宁(杭州)生物医药有限公司 | Gipr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY147327A (en) * | 1995-06-29 | 2012-11-30 | Novartis Ag | Somatostatin peptides |
US5994500A (en) * | 1996-07-19 | 1999-11-30 | 1149336 Ontario Inc. | Antagonists of intestinotrophic GLP-2 peptides |
-
1998
- 1998-06-11 SE SE9802080A patent/SE9802080D0/xx unknown
-
1999
- 1999-06-08 NZ NZ506163A patent/NZ506163A/en unknown
- 1999-06-08 EP EP20030024624 patent/EP1405642A1/en not_active Withdrawn
- 1999-06-08 WO PCT/SE1999/000997 patent/WO1999064060A1/en active IP Right Grant
- 1999-06-08 CA CA2321700A patent/CA2321700C/en not_active Expired - Fee Related
- 1999-06-08 US US09/445,571 patent/US6348447B1/en not_active Expired - Lifetime
- 1999-06-08 HU HU0103147A patent/HUP0103147A3/hu unknown
- 1999-06-08 AU AU46697/99A patent/AU738994B2/en not_active Ceased
- 1999-06-08 EP EP99930089A patent/EP1094834B1/en not_active Expired - Lifetime
- 1999-06-08 ES ES99930089T patent/ES2205845T3/es not_active Expired - Lifetime
- 1999-06-08 DK DK99930089T patent/DK1094834T3/da active
- 1999-06-08 CZ CZ20004491A patent/CZ300873B6/cs not_active IP Right Cessation
- 1999-06-08 DE DE69912434T patent/DE69912434T2/de not_active Expired - Lifetime
- 1999-06-08 JP JP2000553128A patent/JP2002517468A/ja not_active Ceased
- 1999-06-08 AT AT99930089T patent/ATE252912T1/de not_active IP Right Cessation
- 1999-06-08 PL PL343104A patent/PL198802B1/pl not_active IP Right Cessation
- 1999-06-08 RU RU2000133249/14A patent/RU2226402C2/ru not_active IP Right Cessation
- 1999-06-08 PT PT99930089T patent/PT1094834E/pt unknown
-
2000
- 2000-08-10 ZA ZA200004080A patent/ZA200004080B/xx unknown
- 2000-12-06 NO NO20006194A patent/NO327738B1/no not_active IP Right Cessation
-
2010
- 2010-07-01 JP JP2010151403A patent/JP2010270125A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NO20006194L (no) | 2001-01-25 |
NZ506163A (en) | 2004-10-29 |
CZ300873B6 (cs) | 2009-09-02 |
NO327738B1 (no) | 2009-09-14 |
SE9802080D0 (sv) | 1998-06-11 |
JP2002517468A (ja) | 2002-06-18 |
HUP0103147A3 (en) | 2002-02-28 |
AU738994B2 (en) | 2001-10-04 |
WO1999064060A1 (en) | 1999-12-16 |
PT1094834E (pt) | 2004-03-31 |
AU4669799A (en) | 1999-12-30 |
PL343104A1 (en) | 2001-07-30 |
CA2321700C (en) | 2011-05-03 |
ES2205845T3 (es) | 2004-05-01 |
PL198802B1 (pl) | 2008-07-31 |
JP2010270125A (ja) | 2010-12-02 |
ATE252912T1 (de) | 2003-11-15 |
EP1094834B1 (en) | 2003-10-29 |
EP1405642A1 (en) | 2004-04-07 |
HUP0103147A2 (hu) | 2002-01-28 |
NO20006194D0 (no) | 2000-12-06 |
CA2321700A1 (en) | 1999-12-16 |
ZA200004080B (en) | 2001-12-24 |
US6348447B1 (en) | 2002-02-19 |
CZ20004491A3 (en) | 2001-05-16 |
EP1094834A1 (en) | 2001-05-02 |
DE69912434T2 (de) | 2004-05-06 |
RU2226402C2 (ru) | 2004-04-10 |
DE69912434D1 (de) | 2003-12-04 |
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