PT1019195E - Aparelho de elevado gradiente magnetico e metodo de separacao de celulas ou purificacao - Google Patents
Aparelho de elevado gradiente magnetico e metodo de separacao de celulas ou purificacaoInfo
- Publication number
- PT1019195E PT1019195E PT98955422T PT98955422T PT1019195E PT 1019195 E PT1019195 E PT 1019195E PT 98955422 T PT98955422 T PT 98955422T PT 98955422 T PT98955422 T PT 98955422T PT 1019195 E PT1019195 E PT 1019195E
- Authority
- PT
- Portugal
- Prior art keywords
- channel
- separating material
- cells
- container
- purification
- Prior art date
Links
- 238000000926 separation method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
- Y10S977/888—Shaping or removal of materials, e.g. etching
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/948,357 US6241894B1 (en) | 1997-10-10 | 1997-10-10 | High gradient magnetic device and method for cell separation or purification |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1019195E true PT1019195E (pt) | 2003-01-31 |
Family
ID=25487708
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98955422T PT1019195E (pt) | 1997-10-10 | 1998-10-09 | Aparelho de elevado gradiente magnetico e metodo de separacao de celulas ou purificacao |
Country Status (9)
Country | Link |
---|---|
US (1) | US6241894B1 (pt) |
EP (1) | EP1019195B1 (pt) |
AT (1) | ATE223759T1 (pt) |
AU (1) | AU1226999A (pt) |
DE (1) | DE69807905T2 (pt) |
DK (1) | DK1019195T3 (pt) |
ES (1) | ES2184332T3 (pt) |
PT (1) | PT1019195E (pt) |
WO (1) | WO1999019071A1 (pt) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
DE10127069A1 (de) * | 2001-05-23 | 2002-11-28 | Bio Medical Apherese Systeme G | Magnetfilter zur Abtrennung von strömenden magnetischen Objekten |
EP1331035A1 (en) * | 2002-01-23 | 2003-07-30 | F. Hoffmann-La Roche AG | Apparatus for retaining magnetic particles within a flow-through cell |
AU2003216175A1 (en) * | 2002-02-04 | 2003-09-02 | Colorado School Of Mines | Laminar flow-based separations of colloidal and cellular particles |
WO2004029221A2 (en) | 2002-09-27 | 2004-04-08 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
CA2532414C (en) | 2003-07-12 | 2017-03-14 | Accelr8 Technology Corporation | Sensitive and rapid biodetection |
US20120077206A1 (en) | 2003-07-12 | 2012-03-29 | Accelr8 Technology Corporation | Rapid Microbial Detection and Antimicrobial Susceptibility Testing |
WO2005065267A2 (en) * | 2003-12-24 | 2005-07-21 | Massachusetts Institute Of Technology | Magnetophoretic cell clarification |
WO2005084374A2 (en) * | 2004-03-03 | 2005-09-15 | The General Hospital Corporation | Magnetic device for isolation of cells and biomolecules in a microfluidic environment |
US20060171846A1 (en) * | 2005-01-10 | 2006-08-03 | Marr David W M | Microfluidic systems incorporating integrated optical waveguides |
US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US20070059716A1 (en) * | 2005-09-15 | 2007-03-15 | Ulysses Balis | Methods for detecting fetal abnormality |
WO2007044642A2 (en) * | 2005-10-06 | 2007-04-19 | President And Fellows Of Harvard College And Children's Medical Center Corporation | Device and method for combined microfluidic-micromagnetic separation of material in continuous flow |
US9487812B2 (en) | 2012-02-17 | 2016-11-08 | Colorado School Of Mines | Optical alignment deformation spectroscopy |
US9885644B2 (en) | 2006-01-10 | 2018-02-06 | Colorado School Of Mines | Dynamic viscoelasticity as a rapid single-cell biomarker |
US9878326B2 (en) * | 2007-09-26 | 2018-01-30 | Colorado School Of Mines | Fiber-focused diode-bar optical trapping for microfluidic manipulation |
US8119976B2 (en) * | 2007-07-03 | 2012-02-21 | Colorado School Of Mines | Optical-based cell deformability |
US20080007838A1 (en) * | 2006-07-07 | 2008-01-10 | Omnitech Partners, Inc. | Field-of-view indicator, and optical system and associated method employing the same |
US10722250B2 (en) | 2007-09-04 | 2020-07-28 | Colorado School Of Mines | Magnetic-field driven colloidal microbots, methods for forming and using the same |
US20090062828A1 (en) * | 2007-09-04 | 2009-03-05 | Colorado School Of Mines | Magnetic field-based colloidal atherectomy |
DE102007043281A1 (de) | 2007-09-11 | 2009-05-28 | Sebastian Dr. med. Chakrit Bhakdi | Vorrichtung, Materialien und Verfahren zur Hochgradientenmagnetseparation biologischen Materials |
DE102008047855A1 (de) * | 2008-09-18 | 2010-04-22 | Siemens Aktiengesellschaft | Trenneinrichtung zur Trennung von in einer durch einen Trennkanal strömenden Suspension transportierten magnetisierbaren und nichtmagnetisierbaren Teilchen |
WO2010123594A2 (en) * | 2009-01-15 | 2010-10-28 | Children's Medical Center Corporation | Device for filtration of fluids there through and accompanying method |
US8083069B2 (en) * | 2009-07-31 | 2011-12-27 | General Electric Company | High throughput magnetic isolation technique and device for biological materials |
TWI362964B (en) | 2009-12-23 | 2012-05-01 | Ind Tech Res Inst | Magnetic separation device and method for separating magnetic substances in bio-samples |
EP2683831B1 (en) | 2011-03-07 | 2015-09-23 | Accelerate Diagnostics, Inc. | Rapid cell purification systems |
US10254204B2 (en) | 2011-03-07 | 2019-04-09 | Accelerate Diagnostics, Inc. | Membrane-assisted purification |
TWI407101B (zh) | 2011-04-11 | 2013-09-01 | Ind Tech Res Inst | 磁分離單元、磁性分離裝置以及分離生化試樣內磁性物質之方法 |
BR112013024148B1 (pt) | 2011-04-27 | 2022-01-25 | Becton, Dickinson And Company | Dispositivo, método e sistema para separar partes marcadas magneticamente em uma amostra, método de separar partes marcadas magneticamente em uma amostra |
WO2014066553A1 (en) * | 2012-10-26 | 2014-05-01 | Becton, Dickinson And Company | Devices and methods for manipulating components in a fluid sample |
WO2014145152A2 (en) | 2013-03-15 | 2014-09-18 | Gpb Scientific, Llc | On-chip microfluidic processing of particles |
US10324011B2 (en) | 2013-03-15 | 2019-06-18 | The Trustees Of Princeton University | Methods and devices for high throughput purification |
US9677109B2 (en) | 2013-03-15 | 2017-06-13 | Accelerate Diagnostics, Inc. | Rapid determination of microbial growth and antimicrobial susceptibility |
US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
CN105339090B (zh) * | 2013-06-28 | 2017-03-08 | 独立行政法人产业技术综合研究所 | 磁选机用介质以及磁选机 |
US10253355B2 (en) | 2015-03-30 | 2019-04-09 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
EP3278115A2 (en) | 2015-03-30 | 2018-02-07 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
GB201519668D0 (en) * | 2015-11-06 | 2015-12-23 | Ge Healthcare Bio Sciences Ab | Method and chromatography media |
TWI673105B (zh) | 2015-11-18 | 2019-10-01 | 財團法人工業技術研究院 | 磁分離器 |
WO2018024819A1 (en) * | 2016-08-05 | 2018-02-08 | Haute Ecole D'ingenierie Et De Gestion Du Canton De Vaud (Heig-Vd) | Device for removing particles from a material in movement |
BR102016022548B1 (pt) * | 2016-09-28 | 2022-03-22 | José Pancrácio Ribeiro | Matriz magnética ondulada para separador magnético de alta intensidade |
WO2019046052A1 (en) | 2017-09-01 | 2019-03-07 | Gpb Scientific, Llc | METHODS FOR PREPARING THERAPEUTICALLY ACTIVE CELLS USING MICROFLUIDIC |
WO2020058136A1 (en) * | 2018-09-20 | 2020-03-26 | Hemotune Ag | Assembly for magnetic separation-based body fluid purification |
WO2021161221A1 (en) * | 2020-02-11 | 2021-08-19 | Khalifa University of Science and Technology | Systems and methods for enhancing the efficiency of separation processes |
US11529636B2 (en) | 2020-10-09 | 2022-12-20 | Cláudio Henrique Teixeira Ribeiro | Magnetic matrices and methods of using the same |
CN112553043A (zh) * | 2020-12-09 | 2021-03-26 | 深圳先进技术研究院 | 用于胎儿有核红细胞分离纯化的微流控芯片 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB236808A (en) * | 1924-12-02 | 1925-07-16 | Krupp Fried Grusonwerk Ag | Improvements in or relating to zone poles for magnetic separators |
US4212651A (en) * | 1979-05-30 | 1980-07-15 | The United States Of America As Represented By The United States Department Of Energy | High gradient magnetic beneficiation of dry pulverized coal via upwardly directed recirculating fluidization |
US4387286A (en) | 1980-03-26 | 1983-06-07 | Inoue-Japax Research Incorporated | Apparatus for controlling splashes and purification of a machining liquid |
US4560484A (en) * | 1980-04-25 | 1985-12-24 | Purdue Research Foundation | Method and apparatus for magnetically separating particles from a liquid |
US4743364A (en) | 1984-03-16 | 1988-05-10 | Kyrazis Demos T | Magnetic separation of electrically conducting particles from non-conducting material |
US4710472A (en) * | 1985-09-25 | 1987-12-01 | The United States Of America As Represented By The Secretary Of The Navy | Magnetic separation device |
US5512332A (en) * | 1985-10-04 | 1996-04-30 | Immunivest Corporation | Process of making resuspendable coated magnetic particles |
US4795698A (en) * | 1985-10-04 | 1989-01-03 | Immunicon Corporation | Magnetic-polymer particles |
US5076950A (en) * | 1985-12-20 | 1991-12-31 | Syntex (U.S.A.) Inc. | Magnetic composition for particle separation |
DE68916843T2 (de) * | 1988-04-26 | 1995-02-02 | Nippon Telegraph & Telephone | Mikropartikel, Verfahren und Gerät zur Sammlung von Proben zur Verwendung bei der Markierung von Immunreaktionen und Verfahren und Gerät zur Bereitung von Proben. |
US5536475A (en) | 1988-10-11 | 1996-07-16 | Baxter International Inc. | Apparatus for magnetic cell separation |
US5385707A (en) | 1988-12-28 | 1995-01-31 | Stefan Miltenyi | Metal matrices for use in high gradient magnetic separation of biological materials and method for coating the same |
WO1990007380A2 (en) * | 1988-12-28 | 1990-07-12 | Stefan Miltenyi | Methods and materials for high gradient magnetic separation of biological materials |
US5081030A (en) * | 1989-04-25 | 1992-01-14 | The Johns Hopkins University | Release of cells from affinity matrices |
WO1994011078A1 (en) * | 1992-11-16 | 1994-05-26 | Immunivest Corporation | Magnetic immobilization and manipulation of biological entities |
GB9106284D0 (en) * | 1991-03-25 | 1991-05-08 | Cryogenic Consult | Improvements in and relating to magnetic separators |
US5466574A (en) | 1991-03-25 | 1995-11-14 | Immunivest Corporation | Apparatus and methods for magnetic separation featuring external magnetic means |
EP0589636B1 (en) | 1992-09-24 | 2000-08-02 | Amersham Pharmacia Biotech UK Limited | Magnetic separation method and apparatus therefor |
US5514340A (en) * | 1994-01-24 | 1996-05-07 | Magnetix Biotechnology, Inc. | Device for separating magnetically labelled cells |
US5520158A (en) * | 1995-01-12 | 1996-05-28 | Gasmaster International, Inc. | Magnetic field fuel treatment device |
EP0819250B1 (en) * | 1995-04-06 | 2006-09-20 | Miltenyi Biotec Inc. | Multiparameter cell separation using releasable colloidal magnetic particles |
WO1997016835A1 (en) | 1995-11-03 | 1997-05-09 | David Sarnoff Research Center | Magnet |
-
1997
- 1997-10-10 US US08/948,357 patent/US6241894B1/en not_active Expired - Fee Related
-
1998
- 1998-10-09 AT AT98955422T patent/ATE223759T1/de not_active IP Right Cessation
- 1998-10-09 DE DE69807905T patent/DE69807905T2/de not_active Expired - Fee Related
- 1998-10-09 EP EP98955422A patent/EP1019195B1/en not_active Expired - Lifetime
- 1998-10-09 DK DK98955422T patent/DK1019195T3/da active
- 1998-10-09 ES ES98955422T patent/ES2184332T3/es not_active Expired - Lifetime
- 1998-10-09 AU AU12269/99A patent/AU1226999A/en not_active Abandoned
- 1998-10-09 WO PCT/EP1998/006420 patent/WO1999019071A1/en active IP Right Grant
- 1998-10-09 PT PT98955422T patent/PT1019195E/pt unknown
Also Published As
Publication number | Publication date |
---|---|
WO1999019071A1 (en) | 1999-04-22 |
US6241894B1 (en) | 2001-06-05 |
ES2184332T3 (es) | 2003-04-01 |
DE69807905T2 (de) | 2003-05-22 |
AU1226999A (en) | 1999-05-03 |
DE69807905D1 (de) | 2002-10-17 |
ATE223759T1 (de) | 2002-09-15 |
DK1019195T3 (da) | 2002-12-30 |
EP1019195B1 (en) | 2002-09-11 |
EP1019195A1 (en) | 2000-07-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1019195E (pt) | Aparelho de elevado gradiente magnetico e metodo de separacao de celulas ou purificacao | |
WO1998058725A8 (en) | Apparatus for separation and concentration of particles from a fluid stream | |
EP0475533A3 (en) | Method and apparatus for the introduction of a volume of at least one fluid in a tube, in particular suitable for capillary electrophoresis systems and method and apparatus for separating and/or analyzing a fluid material | |
DE60207412D1 (de) | Verfahren, vorrichtung und einrichtung zur nasstrennung von magnetischen mikroteilchen | |
SE9702291D0 (sv) | Anordning för att tillföra en vätska under tryck | |
EP0359900A3 (en) | Process for separating highly molecular substances from liquid culture media, and device for carrying out the process | |
IT8023465A0 (it) | Procedimento e dispositivo per analizzare l'aliquota di sostanze solide in una corrente di convogliamento idraulica composta di particelle solide e di un liquido vettore. | |
DE59606602D1 (de) | Vorrichtung zum filtern und trennen von strömungsmedien | |
IL134404A (en) | Method and apparatus for separating particulate matter from a liquid specimen | |
FI961832A (fi) | Menetelmä ja laite rajapinnan säätämiseksi kahden hallitusti virtaavanja toisistaan erottuvan liuoksen välillä sekä molempien liuosten ulosjohtamiseksi erotustilasta | |
ATE8848T1 (de) | Elektrostatische filtervorrichtung zur reinigung von gasen. | |
DE60212647D1 (de) | Antimikrobielles mittel | |
EP0199470A3 (en) | Method and apparatus for separating complex mixtures of bio-organic materials | |
DE3686714D1 (de) | Elektrophorese-verfahren und vorrichtung zur trennung von teilchen in einem trennmedium. | |
BR9509355A (pt) | Sistema separador e aparelho divisor do tipo classificador | |
ATE256866T1 (de) | Verfahren und vorrichtung zur isoelektrischen teilchentrennung | |
ES2001874A6 (es) | Metodo y aparato para hacer flocular continuamente una pasta de particulas minerales y mejorar su filtracion. | |
IT1240081B (it) | Metodo e apparecchio per bagnare le particelle contenute in un flusso di gas. | |
SE0004352D0 (sv) | System och metod för anslutning av vätskor i ett mikrofluidiskt flödescellsystem | |
DE69508238D1 (de) | Vorrichtung zur reinigung von schwermetalle enthaltendem bodenmaterial | |
EP0005408A3 (en) | Recovery of small particles by flow centrifugation | |
EA199900607A1 (ru) | Устройство для пропускания газа через спекаемый материал | |
HUT39100A (en) | Apparatus for clearing away the floating solid material particles from gaseous medium | |
SE8602816L (sv) | Pa centrifugalprincipen verkande anordning | |
RU94037161A (ru) | Способ разделения жидких гетерогенных систем и устройство для его осуществления |