PT1009768E - Persefina e factores de crescimento relacionados - Google Patents
Persefina e factores de crescimento relacionadosInfo
- Publication number
- PT1009768E PT1009768E PT98948217T PT98948217T PT1009768E PT 1009768 E PT1009768 E PT 1009768E PT 98948217 T PT98948217 T PT 98948217T PT 98948217 T PT98948217 T PT 98948217T PT 1009768 E PT1009768 E PT 1009768E
- Authority
- PT
- Portugal
- Prior art keywords
- persephin
- methods
- growth factors
- mouse
- human
- Prior art date
Links
- 239000003102 growth factor Substances 0.000 title abstract 4
- 102100036660 Persephin Human genes 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 108010070453 persephin Proteins 0.000 abstract 4
- 230000010558 Gene Alterations Effects 0.000 abstract 1
- 102000034615 Glial cell line-derived neurotrophic factor Human genes 0.000 abstract 1
- 108091010837 Glial cell line-derived neurotrophic factor Proteins 0.000 abstract 1
- 101001136670 Homo sapiens Persephin Proteins 0.000 abstract 1
- 101001136669 Mus musculus Persephin Proteins 0.000 abstract 1
- 102100021584 Neurturin Human genes 0.000 abstract 1
- 108010015406 Neurturin Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 101001136668 Rattus norvegicus Persephin Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/931,858 US6222022B1 (en) | 1996-03-14 | 1997-09-16 | Persephin and related growth factors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1009768E true PT1009768E (pt) | 2006-06-30 |
Family
ID=25461462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98948217T PT1009768E (pt) | 1997-09-16 | 1998-09-15 | Persefina e factores de crescimento relacionados |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6222022B1 (enExample) |
| EP (1) | EP1009768B1 (enExample) |
| JP (1) | JP2001516764A (enExample) |
| AT (1) | ATE315581T1 (enExample) |
| AU (1) | AU758011B2 (enExample) |
| CA (1) | CA2296045A1 (enExample) |
| DE (1) | DE69833211T2 (enExample) |
| ES (1) | ES2259458T3 (enExample) |
| IL (1) | IL133834A0 (enExample) |
| NZ (1) | NZ502090A (enExample) |
| PT (1) | PT1009768E (enExample) |
| WO (1) | WO1999014235A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7015316B1 (en) * | 1996-03-14 | 2006-03-21 | Washington University | Polynucleotides encoding human persephin and related growth factors |
| WO2000006731A2 (en) * | 1998-07-31 | 2000-02-10 | Washington University | PERSEPHIN ARF, A PROTEIN ENCODED BY UNSPLICED PERSEPHIN mRNA |
| GB9915200D0 (en) * | 1999-06-29 | 1999-09-01 | Janssen Pharmaceutica Nv | Neurotrophic factor receptor |
| MXPA02002765A (es) * | 1999-09-16 | 2005-09-08 | Prescient Neuropharma Inc | Factores promotores de supervivencia neuronal, opaminergicos y sus usos. |
| HK1054680A1 (zh) | 2000-05-05 | 2003-12-12 | The Research Foundation Of The City University Of New York | 通过调节精氨酸酶和多胺的合成刺激神经系统再生和修复的方法 |
| AUPQ974900A0 (en) * | 2000-08-29 | 2000-09-21 | Macquarie Research Limited | Degenerate oligonucleotide gene-shuffling |
| GB0024550D0 (enExample) | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
| US6376640B1 (en) * | 2001-01-12 | 2002-04-23 | General Electric Company | Melt polycarbonate catalyst systems |
| WO2003099318A2 (en) | 2002-05-29 | 2003-12-04 | DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung | Pancreas-specific proteins |
| EP1463530A4 (en) * | 2001-12-19 | 2006-09-06 | Lijun Wang | ADENO-ASSOCIATED VIRUS-RELATED DELIVERY OF GDNF TO SKELETAL MUSCLES |
| US20060239966A1 (en) * | 2003-10-20 | 2006-10-26 | Tornoee Jens | In vivo gene therapy of parkinson's disease |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5141856A (en) | 1989-01-05 | 1992-08-25 | Synergen, Inc. | Expression of purified ciliary neurotrophic factor |
| US5011914A (en) | 1989-01-05 | 1991-04-30 | Collins Franklin D | Purified ciliary neurotrophic factor |
| US5260417A (en) | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
| US5235043A (en) | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
| MX9205293A (es) | 1991-09-20 | 1993-05-01 | Syntex Sinergen Neuroscience J | Factores neurotrofico derivado del glial |
| WO1995006662A1 (en) | 1993-09-01 | 1995-03-09 | Start Technology Partnership | Neuron regulatory factor for promoting neuron survival |
| AU1443095A (en) | 1993-12-22 | 1995-07-10 | University Of Medicine And Dentistry Of New Jersey | Novel nucleic acid sequences isolated from glial cells |
| US5739307A (en) | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
| WO1997033911A1 (en) * | 1996-03-14 | 1997-09-18 | Washington University | Persephin and related growth factors |
| WO2000006731A2 (en) * | 1998-07-31 | 2000-02-10 | Washington University | PERSEPHIN ARF, A PROTEIN ENCODED BY UNSPLICED PERSEPHIN mRNA |
-
1997
- 1997-09-16 US US08/931,858 patent/US6222022B1/en not_active Expired - Fee Related
-
1998
- 1998-09-15 CA CA002296045A patent/CA2296045A1/en not_active Abandoned
- 1998-09-15 AU AU94838/98A patent/AU758011B2/en not_active Ceased
- 1998-09-15 DE DE69833211T patent/DE69833211T2/de not_active Expired - Lifetime
- 1998-09-15 EP EP98948217A patent/EP1009768B1/en not_active Expired - Lifetime
- 1998-09-15 AT AT98948217T patent/ATE315581T1/de active
- 1998-09-15 JP JP2000511783A patent/JP2001516764A/ja not_active Withdrawn
- 1998-09-15 NZ NZ502090A patent/NZ502090A/xx not_active IP Right Cessation
- 1998-09-15 PT PT98948217T patent/PT1009768E/pt unknown
- 1998-09-15 IL IL13383498A patent/IL133834A0/xx unknown
- 1998-09-15 ES ES98948217T patent/ES2259458T3/es not_active Expired - Lifetime
- 1998-09-15 WO PCT/US1998/019163 patent/WO1999014235A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US6222022B1 (en) | 2001-04-24 |
| DE69833211D1 (de) | 2006-04-06 |
| IL133834A0 (en) | 2001-04-30 |
| EP1009768B1 (en) | 2006-01-11 |
| EP1009768A4 (en) | 2002-06-12 |
| ATE315581T1 (de) | 2006-02-15 |
| JP2001516764A (ja) | 2001-10-02 |
| AU9483898A (en) | 1999-04-05 |
| ES2259458T3 (es) | 2006-10-01 |
| WO1999014235A1 (en) | 1999-03-25 |
| AU758011B2 (en) | 2003-03-13 |
| DE69833211T2 (de) | 2006-09-21 |
| EP1009768A1 (en) | 2000-06-21 |
| CA2296045A1 (en) | 1999-03-25 |
| NZ502090A (en) | 2002-10-25 |
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