PL97723B1 - Sposob wytwarzania rekombinanta szczepu wirusa grypy - Google Patents
Sposob wytwarzania rekombinanta szczepu wirusa grypy Download PDFInfo
- Publication number
- PL97723B1 PL97723B1 PL1974176013A PL17601374A PL97723B1 PL 97723 B1 PL97723 B1 PL 97723B1 PL 1974176013 A PL1974176013 A PL 1974176013A PL 17601374 A PL17601374 A PL 17601374A PL 97723 B1 PL97723 B1 PL 97723B1
- Authority
- PL
- Poland
- Prior art keywords
- strain
- virus
- virulent
- recombinant
- strains
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 9
- 241000700605 Viruses Species 0.000 claims description 56
- 238000000034 method Methods 0.000 claims description 48
- 235000013601 eggs Nutrition 0.000 claims description 41
- 230000000890 antigenic effect Effects 0.000 claims description 15
- 206010022000 influenza Diseases 0.000 claims description 14
- 230000035931 haemagglutination Effects 0.000 claims description 12
- 230000010076 replication Effects 0.000 claims description 10
- 238000011534 incubation Methods 0.000 claims description 9
- 210000002966 serum Anatomy 0.000 claims description 9
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- 239000000427 antigen Substances 0.000 claims description 7
- 102000036639 antigens Human genes 0.000 claims description 7
- 108091007433 antigens Proteins 0.000 claims description 7
- 241000712461 unidentified influenza virus Species 0.000 claims description 7
- 241000287828 Gallus gallus Species 0.000 claims description 6
- 238000002955 isolation Methods 0.000 claims description 6
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- 101001126084 Homo sapiens Piwi-like protein 2 Proteins 0.000 description 3
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- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
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- 230000002068 genetic effect Effects 0.000 description 3
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- 241001494479 Pecora Species 0.000 description 2
- 229930182555 Penicillin Natural products 0.000 description 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 235000017304 Ruaghas Nutrition 0.000 description 2
- 241000554738 Rusa Species 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 210000000991 chicken egg Anatomy 0.000 description 2
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- 229940049954 penicillin Drugs 0.000 description 2
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- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
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- 235000002294 Ilex volkensiana Nutrition 0.000 description 1
- 241000712431 Influenza A virus Species 0.000 description 1
- 241000371980 Influenza B virus (B/Shanghai/361/2002) Species 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
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- 206010027940 Mood altered Diseases 0.000 description 1
- 102000005348 Neuraminidase Human genes 0.000 description 1
- 108010006232 Neuraminidase Proteins 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000035415 Reinfection Diseases 0.000 description 1
- 208000036071 Rhinorrhea Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000109329 Rosa xanthina Species 0.000 description 1
- 241000282898 Sus scrofa Species 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 206010046865 Vaccinia virus infection Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 239000000910 agglutinin Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 229910052788 barium Inorganic materials 0.000 description 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
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- 235000011852 gelatine desserts Nutrition 0.000 description 1
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- 230000001492 haemagglutinating effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
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- 230000006872 improvement Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000001524 infective effect Effects 0.000 description 1
- 229960003971 influenza vaccine Drugs 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Virology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB55469/73A GB1488800A (en) | 1973-11-29 | 1973-11-29 | Influenza vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL97723B1 true PL97723B1 (pl) | 1978-03-30 |
Family
ID=10474009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1974176013A PL97723B1 (pl) | 1973-11-29 | 1974-11-28 | Sposob wytwarzania rekombinanta szczepu wirusa grypy |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3991179A (en, 2012) |
| JP (1) | JPS5094115A (en, 2012) |
| AT (1) | AT331980B (en, 2012) |
| AU (1) | AU498810B2 (en, 2012) |
| BE (1) | BE822736A (en, 2012) |
| CA (1) | CA1044138A (en, 2012) |
| CH (1) | CH616959A5 (en, 2012) |
| CS (1) | CS199569B2 (en, 2012) |
| DE (1) | DE2456636A1 (en, 2012) |
| DK (1) | DK139807B (en, 2012) |
| ES (1) | ES432385A1 (en, 2012) |
| FR (1) | FR2253535B1 (en, 2012) |
| GB (1) | GB1488800A (en, 2012) |
| HU (1) | HU173548B (en, 2012) |
| IE (1) | IE40221B1 (en, 2012) |
| NL (1) | NL7415614A (en, 2012) |
| PL (1) | PL97723B1 (en, 2012) |
| SE (1) | SE422154B (en, 2012) |
| ZA (1) | ZA747602B (en, 2012) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6042209B2 (ja) * | 1974-05-31 | 1985-09-20 | 北里研究所（社団法人） | インフルエンザウイルスの新鮮分離株を発育鶏卵へ短期間で順化させる方法 |
| US4318903A (en) * | 1978-07-12 | 1982-03-09 | Smithkline-Rit | Live influenza virus vaccine and the preparation thereof |
| US4278662A (en) * | 1979-10-16 | 1981-07-14 | Smith Kline - Rit | Attenuated influenza type A virus vaccine |
| US4338296A (en) * | 1979-10-16 | 1982-07-06 | Smithkline-Rit | Influenza virus and process of producing a vaccine therefrom |
| US4554159A (en) * | 1981-11-12 | 1985-11-19 | Institute Merieux | Vaccine and method of immunizing against herpes simplex virus (types 1 and 2) |
| US4743553A (en) * | 1984-07-18 | 1988-05-10 | W. R. Grace & Co. | Synthetic genes for bovine parainfluenza virus |
| US4783411A (en) * | 1984-10-22 | 1988-11-08 | Janis Gabliks | Influenza-A virus vaccine from fish cell cultures |
| WO2005112463A2 (en) * | 2004-05-19 | 2005-11-24 | Alza Corporation | Method and formulation for transdermal delivery of immunologically active agents |
| US7468187B2 (en) | 2005-10-18 | 2008-12-23 | Iowa State University Research Foundation, Inc. | Canine influenza virus and related compositions and methods of use |
-
1973
- 1973-11-29 GB GB55469/73A patent/GB1488800A/en not_active Expired
-
1974
- 1974-11-28 HU HU74WE514A patent/HU173548B/hu unknown
- 1974-11-28 AU AU75876/74A patent/AU498810B2/en not_active Expired
- 1974-11-28 DK DK618274AA patent/DK139807B/da not_active IP Right Cessation
- 1974-11-28 IE IE2447/74A patent/IE40221B1/xx unknown
- 1974-11-28 PL PL1974176013A patent/PL97723B1/pl unknown
- 1974-11-28 ZA ZA00747602A patent/ZA747602B/xx unknown
- 1974-11-28 BE BE150978A patent/BE822736A/xx not_active IP Right Cessation
- 1974-11-28 CS CS748153A patent/CS199569B2/cs unknown
- 1974-11-28 ES ES432385A patent/ES432385A1/es not_active Expired
- 1974-11-28 AT AT953774A patent/AT331980B/de not_active IP Right Cessation
- 1974-11-28 SE SE7414918A patent/SE422154B/xx unknown
- 1974-11-28 CA CA214,815A patent/CA1044138A/en not_active Expired
- 1974-11-29 US US05/528,555 patent/US3991179A/en not_active Expired - Lifetime
- 1974-11-29 DE DE19742456636 patent/DE2456636A1/de not_active Ceased
- 1974-11-29 CH CH1590874A patent/CH616959A5/de not_active IP Right Cessation
- 1974-11-29 NL NL7415614A patent/NL7415614A/xx not_active Application Discontinuation
- 1974-11-29 JP JP49137613A patent/JPS5094115A/ja active Pending
- 1974-12-26 FR FR7442881A patent/FR2253535B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK139807C (en, 2012) | 1979-09-24 |
| GB1488800A (en) | 1977-10-12 |
| DK618274A (en, 2012) | 1975-07-28 |
| DK139807B (da) | 1979-04-23 |
| AU7587674A (en) | 1976-06-03 |
| AU498810B2 (en) | 1979-03-29 |
| FR2253535B1 (en, 2012) | 1978-07-21 |
| AT331980B (de) | 1976-09-10 |
| CA1044138A (en) | 1978-12-12 |
| IE40221L (en) | 1975-05-29 |
| ZA747602B (en) | 1976-07-28 |
| FR2253535A1 (en, 2012) | 1975-07-04 |
| BE822736A (fr) | 1975-05-28 |
| CS199569B2 (en) | 1980-07-31 |
| ES432385A1 (es) | 1977-06-16 |
| SE7414918L (en, 2012) | 1975-05-30 |
| HU173548B (hu) | 1979-06-28 |
| US3991179A (en) | 1976-11-09 |
| DE2456636A1 (de) | 1975-06-05 |
| JPS5094115A (en, 2012) | 1975-07-26 |
| SE422154B (sv) | 1982-02-22 |
| NL7415614A (nl) | 1975-06-02 |
| IE40221B1 (en) | 1979-04-11 |
| CH616959A5 (en, 2012) | 1980-04-30 |
| ATA953774A (de) | 1975-12-15 |
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