PL45717B1 - - Google Patents
Download PDFInfo
- Publication number
- PL45717B1 PL45717B1 PL45717A PL4571759A PL45717B1 PL 45717 B1 PL45717 B1 PL 45717B1 PL 45717 A PL45717 A PL 45717A PL 4571759 A PL4571759 A PL 4571759A PL 45717 B1 PL45717 B1 PL 45717B1
- Authority
- PL
- Poland
- Prior art keywords
- tablets
- phthalate
- zein
- coating
- gastric juice
- Prior art date
Links
- 238000000576 coating method Methods 0.000 claims description 16
- 229920002494 Zein Polymers 0.000 claims description 13
- 239000005019 zein Substances 0.000 claims description 13
- 229940093612 zein Drugs 0.000 claims description 13
- 239000011248 coating agent Substances 0.000 claims description 11
- GVIRAXRGZUXHCI-UHFFFAOYSA-N 2-acetyloxycarbonylbenzoic acid Chemical compound CC(=O)OC(=O)C1=CC=CC=C1C(O)=O GVIRAXRGZUXHCI-UHFFFAOYSA-N 0.000 claims description 10
- 229920002678 cellulose Polymers 0.000 claims description 10
- 239000001913 cellulose Substances 0.000 claims description 10
- 210000004051 gastric juice Anatomy 0.000 claims description 10
- 229940081735 acetylcellulose Drugs 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 claims description 5
- SMEGJBVQLJJKKX-HOTMZDKISA-N [(2R,3S,4S,5R,6R)-5-acetyloxy-3,4,6-trihydroxyoxan-2-yl]methyl acetate Chemical compound CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)OC(=O)C)O)O SMEGJBVQLJJKKX-HOTMZDKISA-N 0.000 claims description 4
- 229920002301 cellulose acetate Polymers 0.000 claims description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 3
- 230000000968 intestinal effect Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 239000003960 organic solvent Substances 0.000 claims description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 10
- 239000003814 drug Substances 0.000 description 10
- 229940079593 drug Drugs 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- FLKPEMZONWLCSK-UHFFFAOYSA-N diethyl phthalate Chemical group CCOC(=O)C1=CC=CC=C1C(=O)OCC FLKPEMZONWLCSK-UHFFFAOYSA-N 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 4
- 238000002156 mixing Methods 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 239000004014 plasticizer Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 206010033799 Paralysis Diseases 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 229920000623 Cellulose acetate phthalate Polymers 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 229920000875 Dissolving pulp Polymers 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 229940081734 cellulose acetate phthalate Drugs 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000011253 protective coating Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000002700 tablet coating Substances 0.000 description 1
- 238000009492 tablet coating Methods 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 231100000925 very toxic Toxicity 0.000 description 1
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL45717B1 true PL45717B1 (enExample) | 1962-04-15 |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3431338A (en) | Coated dosage form adapted to oral emetine or dehydroemetine therapy | |
| US3939259A (en) | Coating composition and therapeutic preparation incorporating same | |
| US4876092A (en) | Sheet-shaped adhesive preparation applicable to oral cavity | |
| US2928770A (en) | Sustained action pill | |
| KR960006063B1 (ko) | 대장에서만 방출할 수 있는 피복시킨 고체 약물형태 | |
| US3109775A (en) | Theophylline-noscapine sustained release composition for treatment of asthma | |
| DK142802B (da) | Fremgangsmåde til fremstilling af terapeutiske præparater til indføring i mavesækken. | |
| TR201905226T4 (tr) | Bir gecikmeli salım ilaç formülasyonu. | |
| AU2007242648B8 (en) | Colonic drug delivery formulation | |
| SI8710681A8 (en) | Process for obtaining new pharmaceutic substance for oral use | |
| CN102552159B (zh) | 雷贝拉唑钠肠溶微丸及其制备方法 | |
| WO1998013029A1 (en) | Oral delayed immediate release formulation and method of preparation therefor | |
| JPH03505448A (ja) | 遅延放出性製剤 | |
| JP5970189B2 (ja) | 医薬調製物 | |
| US3004893A (en) | Enteric coated trypsin and chymotrypsin anti-inflammatory compositions | |
| JPS6348219A (ja) | ジピリダモル又はモピダモルと、０―アセチルサリチル酸とを含む製薬組成物、及びその製造方法 | |
| CA2121038C (en) | Oral preparation for release in lower digestive tracts | |
| EP0425699B1 (en) | Oral preparation which can be released at suitable region in intestine | |
| JPH02106A (ja) | 味覚遮蔽剤を含有している咀嚼可能な薬物錠剤 | |
| JPH0624962A (ja) | 腸溶徐放性製剤 | |
| US2798024A (en) | Composite enteric tablet of erythromycin and sulfonamides | |
| JPS6113683B2 (enExample) | ||
| TW200918107A (en) | Oral pharmaceutical dosage form and manufacturing method thereof | |
| JPS5944311A (ja) | 徐放性顆粒およびその製造法 | |
| EP3741368B1 (en) | Capsule for use in treating ulcerative colitis |