PL447994A1 - Nowe pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów, sposób ich otrzymywania oraz ich zastosowanie - Google Patents

Nowe pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów, sposób ich otrzymywania oraz ich zastosowanie

Info

Publication number
PL447994A1
PL447994A1 PL447994A PL44799424A PL447994A1 PL 447994 A1 PL447994 A1 PL 447994A1 PL 447994 A PL447994 A PL 447994A PL 44799424 A PL44799424 A PL 44799424A PL 447994 A1 PL447994 A1 PL 447994A1
Authority
PL
Poland
Prior art keywords
dihydroquinazolin
sulfonamides
naphthalene
preparation
new derivatives
Prior art date
Application number
PL447994A
Other languages
English (en)
Inventor
Przemysław Zaręba
Anna Karolina Drabczyk
Original Assignee
Politechnika Krakowska im. Tadeusza Kościuszki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Krakowska im. Tadeusza Kościuszki filed Critical Politechnika Krakowska im. Tadeusza Kościuszki
Priority to PL447994A priority Critical patent/PL447994A1/pl
Publication of PL447994A1 publication Critical patent/PL447994A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem zgłoszenia są nowe pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów, którymi według wynalazku są, halogenowane pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów o wzorze ogólnym I, bezrozpuszczalnikowy sposób ich otrzymywania i ich zastosowanie jako ligandy receptora 5-HT6.
PL447994A 2024-03-13 2024-03-13 Nowe pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów, sposób ich otrzymywania oraz ich zastosowanie PL447994A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL447994A PL447994A1 (pl) 2024-03-13 2024-03-13 Nowe pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów, sposób ich otrzymywania oraz ich zastosowanie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL447994A PL447994A1 (pl) 2024-03-13 2024-03-13 Nowe pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów, sposób ich otrzymywania oraz ich zastosowanie

Publications (1)

Publication Number Publication Date
PL447994A1 true PL447994A1 (pl) 2025-09-15

Family

ID=97026304

Family Applications (1)

Application Number Title Priority Date Filing Date
PL447994A PL447994A1 (pl) 2024-03-13 2024-03-13 Nowe pochodne N-(3,4-dihydrochinazolin-2-ylo)naftaleno-1-sulfonamidów, sposób ich otrzymywania oraz ich zastosowanie

Country Status (1)

Country Link
PL (1) PL447994A1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007022946A1 (de) * 2005-08-21 2007-03-01 Abbott Gmbh & Co. Kg Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
KR101730790B1 (ko) * 2015-12-24 2017-04-28 한국과학기술연구원 세로토닌 5-ｈｔ6 저해 활성을 갖는 5,6,7,8-테트라하이드로퀴나졸린-2-아민 화합물

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007022946A1 (de) * 2005-08-21 2007-03-01 Abbott Gmbh & Co. Kg Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
KR101730790B1 (ko) * 2015-12-24 2017-04-28 한국과학기술연구원 세로토닌 5-ｈｔ6 저해 활성을 갖는 5,6,7,8-테트라하이드로퀴나졸린-2-아민 화합물

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PRZEMYSŁAW ZARĘBA I INNI: "Bioorganic Chemistry, 2023, 139, 106730", „NEW CYCLIC ARYLGUANIDINE SCAFFOLDS AS A PLATFORM FOR DEVELOPMENT OF ANTIMICROBIAL AND ANTIVIRAL AGENTS" *
PRZEMYSŁAW ZARĘBA I INNI: "Ultrasonics Sonochemistry, 2022, 90, 106165", „ECO-FRIENDLY METHODS OF SYNTHESIS AND PRELIMINARY BIOLOGICAL EVALUATION OF SULFONAMIDE DERIVATIVES OF CYCLIC ARYLGUANIDINES" *

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