PL4436662T3 - Pochodne naftyrydynonu do leczenia choroby lub zaburzenia - Google Patents

Pochodne naftyrydynonu do leczenia choroby lub zaburzenia

Info

Publication number
PL4436662T3
PL4436662T3 PL22817365.4T PL22817365T PL4436662T3 PL 4436662 T3 PL4436662 T3 PL 4436662T3 PL 22817365 T PL22817365 T PL 22817365T PL 4436662 T3 PL4436662 T3 PL 4436662T3
Authority
PL
Poland
Prior art keywords
disorder
disease
treatment
naphthyridinone derivatives
naphthyridinone
Prior art date
Application number
PL22817365.4T
Other languages
English (en)
Polish (pl)
Inventor
Atwood Kim Cheung
Donglei Liu
Stefan Peukert
Heng GE
Yu GAI
Xingjuan CHANG
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL4436662T3 publication Critical patent/PL4436662T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL22817365.4T 2021-11-23 2022-11-21 Pochodne naftyrydynonu do leczenia choroby lub zaburzenia PL4436662T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163282492P 2021-11-23 2021-11-23
CN2022128601 2022-10-31
PCT/IB2022/061218 WO2023094965A1 (en) 2021-11-23 2022-11-21 Naphthyridinone derivatives for the treatment of a disease or disorder

Publications (1)

Publication Number Publication Date
PL4436662T3 true PL4436662T3 (pl) 2026-02-16

Family

ID=84370237

Family Applications (1)

Application Number Title Priority Date Filing Date
PL22817365.4T PL4436662T3 (pl) 2021-11-23 2022-11-21 Pochodne naftyrydynonu do leczenia choroby lub zaburzenia

Country Status (29)

Country Link
US (2) US12084442B2 (enExample)
EP (2) EP4436662B1 (enExample)
JP (1) JP7826477B2 (enExample)
KR (1) KR20240110040A (enExample)
CN (1) CN118382623A (enExample)
AR (1) AR127698A1 (enExample)
AU (1) AU2022396087A1 (enExample)
CA (1) CA3235682A1 (enExample)
CL (1) CL2024001524A1 (enExample)
CO (1) CO2024006398A2 (enExample)
CR (1) CR20240216A (enExample)
DK (1) DK4436662T3 (enExample)
DO (1) DOP2024000096A (enExample)
EC (1) ECSP24038829A (enExample)
ES (1) ES3054973T3 (enExample)
FI (1) FI4436662T3 (enExample)
HR (1) HRP20251558T1 (enExample)
IL (1) IL312689A (enExample)
JO (1) JOP20240119A1 (enExample)
LT (1) LT4436662T (enExample)
MA (1) MA67325B1 (enExample)
MX (1) MX2024006176A (enExample)
PE (1) PE20241328A1 (enExample)
PL (1) PL4436662T3 (enExample)
PT (1) PT4436662T (enExample)
RS (1) RS67492B9 (enExample)
TW (1) TW202329949A (enExample)
UY (1) UY40025A (enExample)
WO (1) WO2023094965A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20260015867A (ko) * 2023-05-24 2026-02-03 노파르티스 아게 질환 또는 장애 치료용 나프티리디논 유도체

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DK1537114T3 (da) 2002-08-07 2006-11-13 Novartis Ag Organiske forbindelser som midler til behandling af aldosteronmedierede tilstande
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US7612088B2 (en) 2004-05-28 2009-11-03 Speedel Experimenta Ag Heterocyclic compounds and their use as aldosterone synthase inhibitors
CA2568164A1 (en) 2004-05-28 2005-12-15 Speedel Experimenta Ag Heterocyclic compounds and their use as aldosterone synthase inhibitors
WO2006005726A2 (en) 2004-07-09 2006-01-19 Speedel Experimenta Ag Heterocyclic compounds
TW200716636A (en) 2005-05-31 2007-05-01 Speedel Experimenta Ag Heterocyclic spiro-compounds
TW200716634A (en) 2005-05-31 2007-05-01 Speedel Experimenta Ag Heterocyclic spiro-compounds
TW200716105A (en) 2005-05-31 2007-05-01 Speedel Experimenta Ag Imidazole compounds
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
TW200804378A (en) 2005-12-09 2008-01-16 Speedel Experimenta Ag Organic compounds
US20090156875A1 (en) 2006-04-04 2009-06-18 Takafumi Tomioka Methane separation method, methane separation apparatus, and methane utilization system
TW200808812A (en) 2006-04-12 2008-02-16 Speedel Experimenta Ag Imidazo compounds
TW200808813A (en) 2006-04-12 2008-02-16 Speedel Experimenta Ag Imidazo compounds
EP1886695A1 (en) 2006-06-27 2008-02-13 Speedel Experimenta AG Pharmaceutical combination of an aldosterone synthase inhibitor and a glucocorticoid receptor antagonist or a cortisol synthesis inhibitor or a corticotropin releasing factor antagonist
CA2660701A1 (en) 2006-08-25 2008-03-06 Novartis Ag Fused imidazole derivatives for the treatment of disorders mediated by aldosterone synthase and/or 11-beta-hydroxylase and/or aromatase
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KR20090090395A (ko) 2006-12-18 2009-08-25 노파르티스 아게 4-이미다졸릴-1,2,3,4-테트라히드로퀴놀린 유도체 및 알도스테론/11-베타-히드록실라제 억제제로서의 그의 용도
EP2094669A2 (en) 2006-12-18 2009-09-02 Novartis AG 1-substituted imidazole derivatives and their use as aldosterone synthase inhibitors
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HK1201455A1 (en) 2012-01-27 2015-09-04 Gilead Sciences Inc Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
JOP20190086A1 (ar) * 2016-10-21 2019-04-18 Novartis Ag مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب
WO2019241311A1 (en) * 2018-06-11 2019-12-19 Northeastern University Selective ligands for modulation of girk channels
KR20230022829A (ko) 2020-03-03 2023-02-16 트웬티에잇-세븐, 인크. Rna 결합 단백질 또는 rna 변형 단백질을 표적으로 하는 화합물
WO2022074567A1 (en) 2020-10-06 2022-04-14 Novartis Ag Pharmaceutical compositions comprising naphthyridinone derivatives and their use in the treatment of arrhythmia

Also Published As

Publication number Publication date
CA3235682A1 (en) 2023-06-01
TW202329949A (zh) 2023-08-01
UY40025A (es) 2023-06-15
HRP20251558T1 (hr) 2026-01-16
KR20240110040A (ko) 2024-07-12
DOP2024000096A (es) 2024-06-30
PT4436662T (pt) 2025-12-16
US12084442B2 (en) 2024-09-10
EP4436662A1 (en) 2024-10-02
US20230203032A1 (en) 2023-06-29
MA67325B1 (fr) 2025-11-28
RS67492B9 (sr) 2026-02-27
JP7826477B2 (ja) 2026-03-09
ES3054973T3 (en) 2026-02-09
JP2024543107A (ja) 2024-11-19
IL312689A (en) 2024-07-01
EP4656240A1 (en) 2025-12-03
JOP20240119A1 (ar) 2024-05-23
AU2022396087A1 (en) 2024-04-11
CN118382623A (zh) 2024-07-23
AR127698A1 (es) 2024-02-21
PE20241328A1 (es) 2024-06-26
FI4436662T3 (fi) 2025-12-12
WO2023094965A1 (en) 2023-06-01
CO2024006398A2 (es) 2024-07-18
CL2024001524A1 (es) 2024-11-08
LT4436662T (lt) 2025-12-29
MX2024006176A (es) 2024-06-11
CR20240216A (es) 2024-07-01
ECSP24038829A (es) 2024-06-28
DK4436662T3 (da) 2025-12-22
US20250214989A1 (en) 2025-07-03
RS67492B1 (sr) 2025-12-31
EP4436662B1 (en) 2025-09-17

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