PL4301770T3 - Długodziałający agoniści receptora amyliny i ich zastosowania - Google Patents

Długodziałający agoniści receptora amyliny i ich zastosowania

Info

Publication number
PL4301770T3
PL4301770T3 PL22714958.0T PL22714958T PL4301770T3 PL 4301770 T3 PL4301770 T3 PL 4301770T3 PL 22714958 T PL22714958 T PL 22714958T PL 4301770 T3 PL4301770 T3 PL 4301770T3
Authority
PL
Poland
Prior art keywords
acting
long
receptor agonists
amylin receptor
amylin
Prior art date
Application number
PL22714958.0T
Other languages
English (en)
Inventor
Milata Mary Abraham
Daniel Anthony BRIERE
Lili Guo
Samantha Grace Lyons KEYSER
John Lee
Hongchang Qu
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of PL4301770T3 publication Critical patent/PL4301770T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2235—Secretins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL22714958.0T 2021-03-03 2022-03-02 Długodziałający agoniści receptora amyliny i ich zastosowania PL4301770T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163155894P 2021-03-03 2021-03-03
PCT/US2022/018434 WO2022187305A1 (en) 2021-03-03 2022-03-02 Long-acting amylin receptor agonists and uses thereof

Publications (1)

Publication Number Publication Date
PL4301770T3 true PL4301770T3 (pl) 2025-12-08

Family

ID=81327330

Family Applications (1)

Application Number Title Priority Date Filing Date
PL22714958.0T PL4301770T3 (pl) 2021-03-03 2022-03-02 Długodziałający agoniści receptora amyliny i ich zastosowania

Country Status (33)

Country Link
US (2) US12115210B2 (pl)
EP (2) EP4301770B1 (pl)
JP (1) JP7635412B2 (pl)
KR (1) KR20230137987A (pl)
CN (1) CN116917312A (pl)
AR (1) AR126036A1 (pl)
AU (2) AU2022228541C1 (pl)
BR (1) BR112023015038A2 (pl)
CA (1) CA3210140A1 (pl)
CL (1) CL2023002573A1 (pl)
CO (1) CO2023011491A2 (pl)
CR (1) CR20230426A (pl)
DK (1) DK4301770T3 (pl)
DO (1) DOP2023000173A (pl)
EC (1) ECSP23066120A (pl)
ES (1) ES3048909T3 (pl)
FI (1) FI4301770T3 (pl)
HR (1) HRP20251340T1 (pl)
IL (1) IL304885A (pl)
JO (1) JOP20230199A1 (pl)
LT (1) LT4301770T (pl)
MA (1) MA63605B1 (pl)
MD (1) MD4301770T2 (pl)
MX (1) MX2023010319A (pl)
PE (1) PE20232037A1 (pl)
PL (1) PL4301770T3 (pl)
PT (1) PT4301770T (pl)
RS (1) RS67305B1 (pl)
SI (1) SI4301770T1 (pl)
SM (1) SMT202600046T1 (pl)
TW (2) TW202400632A (pl)
UA (1) UA130591C2 (pl)
WO (1) WO2022187305A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240118914A (ko) 2021-01-20 2024-08-05 바이킹 테라퓨틱스 인코포레이티드 대사 및 간 질환 치료를 위한 조성물 및 방법
CA3231953A1 (en) 2021-09-15 2023-03-23 Brian Lian Compositions and methods for the treatment of metabolic and liver disorders
TWI926512B (zh) 2023-11-30 2026-05-21 丹麥商諾佛 儂迪克股份有限公司 Glp-1、gip及澱粉素受體之三重促效劑
KR102991397B1 (ko) 2024-11-29 2026-07-21 노보 노르디스크 에이/에스 Glp-1, gip, 및 아밀린 수용체의 삼중작용제 및 이의 용도

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140011431A (ko) * 2004-02-11 2014-01-28 아밀린 파마슈티칼스, 엘엘씨. 선택가능한 특성을 갖는 하이브리드 폴리펩티드
EP1922336B1 (en) * 2005-08-11 2012-11-21 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
CN101400698A (zh) 2006-03-15 2009-04-01 诺沃-诺迪斯克有限公司 胰岛淀粉样多肽衍生物
EP2036923A1 (en) 2007-09-11 2009-03-18 Novo Nordisk A/S Improved derivates of amylin
WO2010046357A1 (en) * 2008-10-21 2010-04-29 Novo Nordisk A/S Amylin derivatives
JP2014516049A (ja) 2011-05-25 2014-07-07 アミリン・ファーマシューティカルズ,リミテッド・ライアビリティ・カンパニー アミリンペプチドおよび誘導体ならびにそれらの使用
EP2718315B1 (en) * 2011-06-10 2017-12-27 Novo Nordisk A/S Pramlintide derivatives
DK2729160T3 (da) * 2011-07-08 2019-07-01 Aegerion Pharmaceuticals Inc Manipulerede polypeptider, der har forbedret virkningstid og reduceret immunogenicitet
PL2838914T3 (pl) * 2012-04-19 2017-11-30 Novo Nordisk A/S Analogi ludzkiej amyliny
WO2015168488A2 (en) * 2014-05-02 2015-11-05 The Research Foundation For The State University Of New York Islet amyloid polypeptides with improved solubility
AR109514A1 (es) 2016-09-09 2018-12-19 Zealand Pharma As Análogos de amilina
AU2019357621B2 (en) 2018-10-11 2025-04-03 Intarcia Therapeutics, Inc. Human amylin analog polypeptides and methods of use
WO2020225781A1 (en) * 2019-05-08 2020-11-12 Auckland Uniservices Limited Peptide conjugate amylin agonists and uses thereof
KR20230073176A (ko) 2020-09-24 2023-05-25 구브라 에이피에스 개선된 아밀린 수용체(hAMY3R) 효능을 갖는 HAM15-52 유사체

Also Published As

Publication number Publication date
JP2025090588A (ja) 2025-06-17
AR126036A1 (es) 2023-09-06
ES3048909T3 (en) 2025-12-12
AU2024219783A1 (en) 2024-10-10
CO2023011491A2 (es) 2023-09-18
US20250025533A1 (en) 2025-01-23
HRP20251340T1 (hr) 2025-12-19
US12115210B2 (en) 2024-10-15
EP4301770A1 (en) 2024-01-10
CL2023002573A1 (es) 2024-05-24
WO2022187305A1 (en) 2022-09-09
AU2022228541C1 (en) 2025-11-13
AU2022228541A1 (en) 2023-08-17
PT4301770T (pt) 2025-10-21
RS67305B1 (sr) 2025-11-28
AU2022228541A9 (en) 2024-05-16
SI4301770T1 (sl) 2025-12-31
DOP2023000173A (es) 2023-10-15
CR20230426A (es) 2023-10-03
AU2022228541B2 (en) 2024-06-20
DK4301770T3 (da) 2025-10-20
KR20230137987A (ko) 2023-10-05
CN116917312A (zh) 2023-10-20
CA3210140A1 (en) 2022-09-09
EP4301770B1 (en) 2025-08-27
JP2024508312A (ja) 2024-02-26
EP4643872A2 (en) 2025-11-05
MA63605B1 (fr) 2025-09-30
PE20232037A1 (es) 2023-12-21
TW202300508A (zh) 2023-01-01
MD4301770T2 (ro) 2026-01-31
JP7635412B2 (ja) 2025-02-25
LT4301770T (lt) 2025-11-10
MX2023010319A (es) 2023-09-14
TWI815327B (zh) 2023-09-11
JOP20230199A1 (ar) 2023-08-31
TW202400632A (zh) 2024-01-01
ECSP23066120A (es) 2023-10-31
EP4643872A3 (en) 2025-11-26
BR112023015038A2 (pt) 2023-11-28
IL304885A (en) 2023-10-01
US20220288168A1 (en) 2022-09-15
US12551532B2 (en) 2026-02-17
FI4301770T3 (fi) 2025-10-15
UA130591C2 (uk) 2026-03-25
SMT202600046T1 (it) 2026-03-09

Similar Documents

Publication Publication Date Title
SMT202600046T1 (it) Agonisti di recettori di amilina con azione a lunga durata e loro usi
IL279300A (en) 1-GLP agonist receptors and their use
IL279224B1 (en) 1-glp agonist receptors and their use
IL269068A (en) Paranoid X receptor agonists and uses thereof
PT3807267T (pt) Agonistas do recetor da hormona da tiroide e usos dos mesmos
SI3609888T1 (sl) Agonisti farnezoidnega receptorja x in njihove uporabe
ZA201904616B (en) Glp-1 receptor agonists and uses thereof
IL281471A (en) Farnesoid x receptor agonists and uses thereof
IL308099A (en) Orexin receptor agonists and uses thereof
IL281474A (en) Farnesoid x receptor agonists and uses thereof
IL270634A (en) Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods
PL4021929T3 (pl) Analogi ham15-52 z poprawioną si‎łą działania receptora amyliny (hamy3r)
GB202003762D0 (en) GLP receptor agonists
GB201816637D0 (en) Selective somatostatin receptor agonists
HK40093975A (en) Dual amylin and calcitonin receptor agonists and uses thereof
GB201903900D0 (en) Adenosine receptor agonists
CA3275750A1 (en) Amylin receptor agonists
HK40079209A (en) Glp receptor agonists
IL305242B1 (en) New glucocorticoid receptor agonists
GB201903985D0 (en) GLP receptor agonists
IL317600B2 (en) AMYLIN RECEPTOR (hAMY3R) AGONISTS WITH IMPROVED CHEMICAL STABILITY
HK40107459A (en) Orexin receptor agonists and uses thereof
GB202003764D0 (en) Oral GLP receptor agonists
GB202003766D0 (en) Oral GLP receptor agonists
GB201903953D0 (en) Oral GLP receptor agonists