ECSP23066120A - Agonistas del receptor de amilina de acción prolongada y usos de estos - Google Patents
Agonistas del receptor de amilina de acción prolongada y usos de estosInfo
- Publication number
- ECSP23066120A ECSP23066120A ECSENADI202366120A ECDI202366120A ECSP23066120A EC SP23066120 A ECSP23066120 A EC SP23066120A EC SENADI202366120 A ECSENADI202366120 A EC SENADI202366120A EC DI202366120 A ECDI202366120 A EC DI202366120A EC SP23066120 A ECSP23066120 A EC SP23066120A
- Authority
- EC
- Ecuador
- Prior art keywords
- compounds
- amylin receptor
- acting
- long
- receptor agonists
- Prior art date
Links
- 108091005466 amylin receptors Proteins 0.000 title abstract 2
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 2
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- 235000020824 obesity Nutrition 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 235000012631 food intake Nutrition 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 206010053219 non-alcoholic steatohepatitis Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 150000003626 triacylglycerols Chemical class 0.000 abstract 1
- 238000004260 weight control Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2235—Secretins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente descripción se relaciona con el campo de la medicina. Más particularmente, la descripción pertenece al campo del tratamiento de la diabetes, la obesidad y/o el control crónico del peso, la dislipidemia y/o la NASH. La descripción se relaciona con compuestos que actúan como agonistas del receptor de amilina y pueden reducir la ingestión de alimentos, el peso corporal, la glucosa y/o los triglicéridos, por lo que pueden usarse para tratar la diabetes, la obesidad y/o la dislipidemia. La presente descripción también incluye composiciones farmacéuticas que contienen tales compuestos y usos terapéuticos de tales compuestos y composiciones.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163155894P | 2021-03-03 | 2021-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP23066120A true ECSP23066120A (es) | 2023-10-31 |
Family
ID=81327330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSENADI202366120A ECSP23066120A (es) | 2021-03-03 | 2023-09-01 | Agonistas del receptor de amilina de acción prolongada y usos de estos |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20220288168A1 (es) |
| EP (1) | EP4301770A1 (es) |
| JP (1) | JP2024508312A (es) |
| KR (1) | KR20230137987A (es) |
| CN (1) | CN116917312A (es) |
| AR (1) | AR126036A1 (es) |
| AU (1) | AU2022228541B2 (es) |
| BR (1) | BR112023015038A2 (es) |
| CA (1) | CA3210140A1 (es) |
| CL (1) | CL2023002573A1 (es) |
| CO (1) | CO2023011491A2 (es) |
| CR (1) | CR20230426A (es) |
| DO (1) | DOP2023000173A (es) |
| EC (1) | ECSP23066120A (es) |
| IL (1) | IL304885A (es) |
| MX (1) | MX2023010319A (es) |
| PE (1) | PE20232037A1 (es) |
| TW (2) | TWI815327B (es) |
| WO (1) | WO2022187305A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3204051A1 (en) | 2021-01-20 | 2022-07-28 | Brian Lian | Compositions and methods for the treatment of metabolic and liver disorders |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2330124B1 (en) * | 2005-08-11 | 2015-02-25 | Amylin Pharmaceuticals, LLC | Hybrid polypeptides with selectable properties |
| EP2036923A1 (en) | 2007-09-11 | 2009-03-18 | Novo Nordisk A/S | Improved derivates of amylin |
| WO2010046357A1 (en) | 2008-10-21 | 2010-04-29 | Novo Nordisk A/S | Amylin derivatives |
| US8575090B2 (en) * | 2011-06-10 | 2013-11-05 | Novo Nordisk A/S | Amylin analogues and pharmaceutical compositions thereof |
| ES2732475T3 (es) * | 2011-07-08 | 2019-11-22 | Aegerion Pharmaceuticals Inc | Polipéptidos modificados por ingeniería genética que tienen una duración potenciada de la acción y una inmunogenicidad reducida |
| US8575091B1 (en) * | 2012-04-19 | 2013-11-05 | Novo Nordisk A/S | Amylin analogues and pharmaceutical compositions thereof |
| CN104395338B (zh) * | 2012-04-19 | 2019-05-10 | 诺和诺德股份有限公司 | 人胰岛淀粉样多肽类似物 |
| CA2947587C (en) * | 2014-05-02 | 2022-10-18 | The Research Foundation For The State University Of New York | Islet amyloid polypeptides with improved solubility |
| WO2020225781A1 (en) * | 2019-05-08 | 2020-11-12 | Auckland Uniservices Limited | Peptide conjugate amylin agonists and uses thereof |
-
2022
- 2022-03-01 TW TW111107293A patent/TWI815327B/zh active
- 2022-03-01 TW TW112134208A patent/TW202400632A/zh unknown
- 2022-03-02 WO PCT/US2022/018434 patent/WO2022187305A1/en active Application Filing
- 2022-03-02 CA CA3210140A patent/CA3210140A1/en active Pending
- 2022-03-02 AR ARP220100459A patent/AR126036A1/es unknown
- 2022-03-02 CR CR20230426A patent/CR20230426A/es unknown
- 2022-03-02 EP EP22714958.0A patent/EP4301770A1/en active Pending
- 2022-03-02 CN CN202280018226.7A patent/CN116917312A/zh active Pending
- 2022-03-02 KR KR1020237029462A patent/KR20230137987A/ko active Search and Examination
- 2022-03-02 JP JP2023553248A patent/JP2024508312A/ja active Pending
- 2022-03-02 IL IL304885A patent/IL304885A/en unknown
- 2022-03-02 PE PE2023002460A patent/PE20232037A1/es unknown
- 2022-03-02 MX MX2023010319A patent/MX2023010319A/es unknown
- 2022-03-02 AU AU2022228541A patent/AU2022228541B2/en active Active
- 2022-03-02 BR BR112023015038A patent/BR112023015038A2/pt unknown
- 2022-03-02 US US17/684,578 patent/US20220288168A1/en active Pending
-
2023
- 2023-08-30 CL CL2023002573A patent/CL2023002573A1/es unknown
- 2023-08-30 DO DO2023000173A patent/DOP2023000173A/es unknown
- 2023-08-30 CO CONC2023/0011491A patent/CO2023011491A2/es unknown
- 2023-09-01 EC ECSENADI202366120A patent/ECSP23066120A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DOP2023000173A (es) | 2023-10-15 |
| KR20230137987A (ko) | 2023-10-05 |
| CR20230426A (es) | 2023-10-03 |
| IL304885A (en) | 2023-10-01 |
| PE20232037A1 (es) | 2023-12-21 |
| WO2022187305A1 (en) | 2022-09-09 |
| AU2022228541A1 (en) | 2023-08-17 |
| MX2023010319A (es) | 2023-09-14 |
| TW202400632A (zh) | 2024-01-01 |
| CA3210140A1 (en) | 2022-09-09 |
| CL2023002573A1 (es) | 2024-05-24 |
| CN116917312A (zh) | 2023-10-20 |
| US20220288168A1 (en) | 2022-09-15 |
| BR112023015038A2 (pt) | 2023-11-28 |
| AU2022228541A9 (en) | 2024-05-16 |
| TW202300508A (zh) | 2023-01-01 |
| AR126036A1 (es) | 2023-09-06 |
| CO2023011491A2 (es) | 2023-09-18 |
| EP4301770A1 (en) | 2024-01-10 |
| AU2022228541B2 (en) | 2024-06-20 |
| TWI815327B (zh) | 2023-09-11 |
| JP2024508312A (ja) | 2024-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CL2019001144A1 (es) | Dímeros de insulina, agonistas parciales del receptor de insulina (divisional solicitud 201701288) | |
| ECSP23045245A (es) | Agonistas duales del receptor de amilina y calcitonina y usos de los mismos | |
| ECSP23066120A (es) | Agonistas del receptor de amilina de acción prolongada y usos de estos | |
| CO2020014180A2 (es) | Derivados de gip y usos de estos | |
| BR112022022331A2 (pt) | Método para melhorar efeitos terapêuticos positivos de um psicodélico, composição, e método para tratar um paciente | |
| EA201790568A1 (ru) | Применение двойного агониста рецепторов glp-1/глюкагона пролонгированного действия для лечения неалкогольной жировой болезни печени | |
| EA201800199A1 (ru) | Применение akkermansia muciniphila для лечения метаболических расстройств, увеличения расхода энергии и снижения веса, композиции, лекарственное стедство | |
| CL2017000201A1 (es) | Composiciones y métodos de uso para tratar trastornos metabólicos | |
| CO2019007409A2 (es) | Derivados de la pirimidin enona tricíclica para la inhibición de rorγ y otros usos | |
| BR112016008540A2 (pt) | análogos de glucagon | |
| EA201991345A1 (ru) | Новые соединения в качестве пептидных тройных агонистов рецепторов glp1/глюкагона/gip | |
| PE20211202A1 (es) | Composiciones de glp-1 y sus usos | |
| DOP2012000246A (es) | Composiciones de anticuerpos anti-factor de crecimiento nervioso (ngf) | |
| CL2022002813A1 (es) | Semaglutida para el tratamiento de esteatohepatitis no alcoholica. | |
| MX2017006938A (es) | Terapia de combinacion para el tratamiento de cancer. | |
| CL2019001586A1 (es) | Insulina que contiene composiciones farmacéuticas. | |
| BR112016027435A2 (pt) | formulação inovadora de meloxicam | |
| EA201992272A1 (ru) | Ацилированное инсулиновое соединение | |
| BR112014011641A2 (pt) | composto; composição; uso de um composto; método para tratar pelo menos uma doença, distúrbio ou condição selecionada de obesidade, sobrepeso ou distribuição de gordura anormal e condições ou doenças associadas com os mesmos em um sujeito em necessidade do mesmo; método para remodelar tecido adiposo branco para tecido adiposo tipo marrom em um sujeito; método para tratar uma doença, distúrbio ou condição associada com ou se beneficiando da remodelação de tecido adiposo branco para tecido adiposo tipo marrom em um sujeito; e método para reduzir o tecido adiposo branco (wat) em um sujeito em necessidade do mesmo | |
| JOP20210201A1 (ar) | مركب لخفض جلوكوز الدم | |
| BR112023000747A2 (pt) | Composições para o tratamento de obesidade | |
| CO2024006728A2 (es) | Derivados del ácido 3-fenil-1-benzotiofeno-2-carboxílico como inhibidores de la quinasa deshidrogenasa de alfa cetoácidos de cadena ramificada para el tratamiento de la diabetes, enfermedades renales, nash e insuficiencia cardiaca | |
| BR112015023806A2 (pt) | Novos regimes de dosagem de celgosivir para o tratamento de dengue | |
| CO2020002500A2 (es) | Análogos de insulina acilados novedosos y usos de estos | |
| BR112017022478A2 (pt) | composição farmacêutica de liberação sustentada que contém rivastigmina |