PL4301770T3 - Długodziałający agoniści receptora amyliny i ich zastosowania - Google Patents

Długodziałający agoniści receptora amyliny i ich zastosowania

Info

Publication number
PL4301770T3
PL4301770T3 PL22714958.0T PL22714958T PL4301770T3 PL 4301770 T3 PL4301770 T3 PL 4301770T3 PL 22714958 T PL22714958 T PL 22714958T PL 4301770 T3 PL4301770 T3 PL 4301770T3
Authority
PL
Poland
Prior art keywords
acting
long
receptor agonists
amylin receptor
amylin
Prior art date
Application number
PL22714958.0T
Other languages
English (en)
Inventor
Milata Mary Abraham
Daniel Anthony BRIERE
Lili Guo
Samantha Grace Lyons KEYSER
John Lee
Hongchang Qu
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of PL4301770T3 publication Critical patent/PL4301770T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2235—Secretins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL22714958.0T 2021-03-03 2022-03-02 Długodziałający agoniści receptora amyliny i ich zastosowania PL4301770T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163155894P 2021-03-03 2021-03-03
PCT/US2022/018434 WO2022187305A1 (en) 2021-03-03 2022-03-02 Long-acting amylin receptor agonists and uses thereof

Publications (1)

Publication Number Publication Date
PL4301770T3 true PL4301770T3 (pl) 2025-12-08

Family

ID=81327330

Family Applications (1)

Application Number Title Priority Date Filing Date
PL22714958.0T PL4301770T3 (pl) 2021-03-03 2022-03-02 Długodziałający agoniści receptora amyliny i ich zastosowania

Country Status (33)

Country Link
US (2) US12115210B2 (pl)
EP (2) EP4301770B1 (pl)
JP (2) JP7635412B2 (pl)
KR (1) KR20230137987A (pl)
CN (1) CN116917312A (pl)
AR (1) AR126036A1 (pl)
AU (2) AU2022228541C1 (pl)
BR (1) BR112023015038A2 (pl)
CA (1) CA3210140A1 (pl)
CL (1) CL2023002573A1 (pl)
CO (1) CO2023011491A2 (pl)
CR (1) CR20230426A (pl)
DK (1) DK4301770T3 (pl)
DO (1) DOP2023000173A (pl)
EC (1) ECSP23066120A (pl)
ES (1) ES3048909T3 (pl)
FI (1) FI4301770T3 (pl)
HR (1) HRP20251340T1 (pl)
IL (1) IL304885A (pl)
JO (1) JOP20230199A1 (pl)
LT (1) LT4301770T (pl)
MA (1) MA63605B1 (pl)
MD (1) MD4301770T2 (pl)
MX (1) MX2023010319A (pl)
PE (1) PE20232037A1 (pl)
PL (1) PL4301770T3 (pl)
PT (1) PT4301770T (pl)
RS (1) RS67305B1 (pl)
SI (1) SI4301770T1 (pl)
SM (1) SMT202600046T1 (pl)
TW (2) TW202400632A (pl)
UA (1) UA130591C2 (pl)
WO (1) WO2022187305A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022159395A1 (en) 2021-01-20 2022-07-28 Viking Therapeutics, Inc. Compositions and methods for the treatment of metabolic and liver disorders
IL311411A (en) 2021-09-15 2024-05-01 Viking Therapeutics Inc Preparations and methods for the treatment of metabolic and liver disorders
WO2025114501A1 (en) 2023-11-30 2025-06-05 Novo Nordisk A/S Tri-agonists of the glp-1, gip, and amylin receptors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060094652A1 (en) 2004-02-11 2006-05-04 Levy Odile E Hybrid polypeptides with selectable properties
AU2006279680B2 (en) * 2005-08-11 2012-12-06 Amylin Pharmaceuticals, Llc Hybrid polypeptides with selectable properties
JP5252435B2 (ja) 2006-03-15 2013-07-31 ノボ・ノルデイスク・エー/エス アミリン誘導体
EP2036923A1 (en) 2007-09-11 2009-03-18 Novo Nordisk A/S Improved derivates of amylin
WO2010046357A1 (en) * 2008-10-21 2010-04-29 Novo Nordisk A/S Amylin derivatives
MX2013013802A (es) 2011-05-25 2014-04-25 Amylin Pharmaceuticals Llc Peptidos de amilina y derivados y usos de los mismos.
KR102066987B1 (ko) 2011-06-10 2020-01-16 노보 노르디스크 에이/에스 폴리펩티드
ES2732475T3 (es) * 2011-07-08 2019-11-22 Aegerion Pharmaceuticals Inc Polipéptidos modificados por ingeniería genética que tienen una duración potenciada de la acción y una inmunogenicidad reducida
ES2640285T3 (es) * 2012-04-19 2017-11-02 Novo Nordisk A/S Análogos de amilina humana
EP3137494B1 (en) * 2014-05-02 2021-08-04 The Research Foundation for The State University of New York Islet amyloid polypeptides with improved solubility
AR109514A1 (es) 2016-09-09 2018-12-19 Zealand Pharma As Análogos de amilina
KR102911883B1 (ko) 2018-10-11 2026-01-13 인타르시아 세라퓨틱스 인코포레이티드 인간 아밀린 유사체 폴리펩타이드 및 사용 방법
WO2020225781A1 (en) * 2019-05-08 2020-11-12 Auckland Uniservices Limited Peptide conjugate amylin agonists and uses thereof
IL300620B2 (en) 2020-09-24 2025-12-01 Gubra As Ham15-52 analogues with improved amylin receptor (hamy3r) potency

Also Published As

Publication number Publication date
ES3048909T3 (en) 2025-12-12
EP4301770B1 (en) 2025-08-27
EP4643872A3 (en) 2025-11-26
AU2022228541C1 (en) 2025-11-13
JP2025090588A (ja) 2025-06-17
US20220288168A1 (en) 2022-09-15
TWI815327B (zh) 2023-09-11
RS67305B1 (sr) 2025-11-28
AU2022228541A9 (en) 2024-05-16
MX2023010319A (es) 2023-09-14
SMT202600046T1 (it) 2026-03-09
SI4301770T1 (sl) 2025-12-31
DK4301770T3 (da) 2025-10-20
JP2024508312A (ja) 2024-02-26
CO2023011491A2 (es) 2023-09-18
HRP20251340T1 (hr) 2025-12-19
BR112023015038A2 (pt) 2023-11-28
PT4301770T (pt) 2025-10-21
LT4301770T (lt) 2025-11-10
FI4301770T3 (fi) 2025-10-15
AR126036A1 (es) 2023-09-06
MA63605B1 (fr) 2025-09-30
PE20232037A1 (es) 2023-12-21
JP7635412B2 (ja) 2025-02-25
TW202300508A (zh) 2023-01-01
US20250025533A1 (en) 2025-01-23
MD4301770T2 (ro) 2026-01-31
WO2022187305A1 (en) 2022-09-09
CN116917312A (zh) 2023-10-20
US12551532B2 (en) 2026-02-17
CR20230426A (es) 2023-10-03
US12115210B2 (en) 2024-10-15
TW202400632A (zh) 2024-01-01
AU2022228541A1 (en) 2023-08-17
IL304885A (en) 2023-10-01
CA3210140A1 (en) 2022-09-09
JOP20230199A1 (ar) 2023-08-31
DOP2023000173A (es) 2023-10-15
EP4643872A2 (en) 2025-11-05
KR20230137987A (ko) 2023-10-05
EP4301770A1 (en) 2024-01-10
AU2022228541B2 (en) 2024-06-20
UA130591C2 (uk) 2026-03-25
ECSP23066120A (es) 2023-10-31
CL2023002573A1 (es) 2024-05-24
AU2024219783A1 (en) 2024-10-10

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