PL4118092T3 - Immunomodulujące o‑het‑arylowe azalidy - Google Patents

Immunomodulujące o‑het‑arylowe azalidy

Info

Publication number
PL4118092T3
PL4118092T3 PL21716891.3T PL21716891T PL4118092T3 PL 4118092 T3 PL4118092 T3 PL 4118092T3 PL 21716891 T PL21716891 T PL 21716891T PL 4118092 T3 PL4118092 T3 PL 4118092T3
Authority
PL
Poland
Prior art keywords
azalides
immunomodulating
het
aryl
aryl azalides
Prior art date
Application number
PL21716891.3T
Other languages
English (en)
Inventor
Richard Andrew Ewin
Mark R. Cox
Imelda HOT
Matthew W. Bedore
Tomasz RESPONDEK
Susan M.K. SHEEHAN
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of PL4118092T3 publication Critical patent/PL4118092T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Fodder In General (AREA)
  • Saccharide Compounds (AREA)
PL21716891.3T 2020-03-12 2021-03-11 Immunomodulujące o‑het‑arylowe azalidy PL4118092T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062988492P 2020-03-12 2020-03-12
PCT/US2021/021906 WO2021183762A1 (en) 2020-03-12 2021-03-11 Immunomodulating o-het-aryl azalides

Publications (1)

Publication Number Publication Date
PL4118092T3 true PL4118092T3 (pl) 2025-10-20

Family

ID=75278424

Family Applications (2)

Application Number Title Priority Date Filing Date
PL21715446.7T PL4118091T3 (pl) 2020-03-12 2021-03-11 Immunomodulujące azalidy mocznikowe
PL21716891.3T PL4118092T3 (pl) 2020-03-12 2021-03-11 Immunomodulujące o‑het‑arylowe azalidy

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL21715446.7T PL4118091T3 (pl) 2020-03-12 2021-03-11 Immunomodulujące azalidy mocznikowe

Country Status (19)

Country Link
US (5) US20230129438A1 (pl)
EP (2) EP4118091B1 (pl)
JP (2) JP7779845B2 (pl)
KR (1) KR20220156570A (pl)
CN (2) CN115461353B (pl)
AR (1) AR121554A1 (pl)
AU (2) AU2021233895B2 (pl)
BR (1) BR112022017779A2 (pl)
CA (1) CA3175087A1 (pl)
DK (1) DK4118091T3 (pl)
ES (1) ES3038279T3 (pl)
HU (2) HUE072784T2 (pl)
MX (2) MX2022011242A (pl)
PL (2) PL4118091T3 (pl)
PT (1) PT4118091T (pl)
SI (1) SI4118091T1 (pl)
TW (2) TWI830987B (pl)
WO (4) WO2021183758A1 (pl)
ZA (1) ZA202209530B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI830987B (zh) 2020-03-12 2024-02-01 美商碩騰服務公司 免疫調節脲氮雜內酯
MX2024002892A (es) 2021-09-07 2024-04-05 Zoetis Services Llc Azalidos inmunomoduladores.
PE20231034A1 (es) 2023-04-05 2023-07-10 Agrovet Market S A Composicion farmaceutica inyectable que comprende tilvalosina tartrato y su metodo de fabricacion

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985844A (en) 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
HN1998000074A (es) * 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos
IT1306205B1 (it) 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
BRPI0017013B1 (pt) 2000-01-27 2015-07-14 Zoetis P Llc Composição de antibiótico azalídeo e método para sua obtenção
BR0110382A (pt) 2000-04-27 2003-06-24 Pfizer Prod Inc Utilização de composições antibióticas azalida para o tratamento ou prevenção de uma infecção causada por bactérias ou protozoários em mamìferos
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
ITMI20040124A1 (it) 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
PT1851236E (pt) * 2005-01-13 2010-10-25 Glaxosmithkline Zagreb Macrólidos com actividade anti-inflamatória
ES2343748T3 (es) * 2005-07-06 2010-08-09 Zambon S.P.A. Formas cristalinas de compuestos macrolidos dotados de una actividad antiinflamatoria.
RU2455308C2 (ru) * 2006-05-01 2012-07-10 Тайсо Фармасьютикал Ко., Лтд. Макролидные производные
EP2188281A1 (en) 2007-08-10 2010-05-26 Y's Therapeutics Co, Ltd. Modulation of immune responses by administration of roxithromycin or its derivative
WO2009106419A1 (en) 2008-02-08 2009-09-03 Basilea Pharmaceutica Ag New macrolides and their use
EP2271656A1 (en) 2008-04-23 2011-01-12 Glaxo Group Limited 2'-o,3'-n-bridged macrolides
CN102378763A (zh) 2009-01-30 2012-03-14 葛兰素集团有限公司 消炎的大环内酯
ES2582794T3 (es) * 2009-08-13 2016-09-15 Basilea Pharmaceutica Ag Nuevos macrólidos y su uso
WO2011116312A1 (en) 2010-03-19 2011-09-22 Catabasis Pharmaceuticals, Inc. Fatty acid macrolide derivatives and their uses
WO2011131749A1 (en) 2010-04-23 2011-10-27 Glaxo Group Limited New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases
AU2013239679A1 (en) * 2012-03-27 2014-10-30 Michael W. BURNET Anti-inflammatory macrolides
US20160031925A1 (en) 2013-04-10 2016-02-04 Probiotic Pharmaceuticals Aps Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect
GB201520419D0 (en) 2015-11-19 2016-01-06 Epi Endo Pharmaceuticals Ehf Compounds
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
TWI830987B (zh) 2020-03-12 2024-02-01 美商碩騰服務公司 免疫調節脲氮雜內酯

Also Published As

Publication number Publication date
TWI847935B (zh) 2024-07-01
AU2021232959B2 (en) 2023-09-07
MX2022011240A (es) 2022-12-15
WO2021183754A1 (en) 2021-09-16
AU2021233895A1 (en) 2022-09-29
JP7779845B2 (ja) 2025-12-03
US11771677B2 (en) 2023-10-03
US12390441B2 (en) 2025-08-19
BR112022017779A2 (pt) 2022-11-29
PL4118091T3 (pl) 2025-09-15
US12390440B2 (en) 2025-08-19
EP4118092A1 (en) 2023-01-18
WO2021183762A1 (en) 2021-09-16
CN115461352B (zh) 2026-01-27
MX2022011242A (es) 2022-12-15
BR112022017015A2 (pt) 2022-11-16
PT4118091T (pt) 2025-08-20
US20230129438A1 (en) 2023-04-27
SI4118091T1 (sl) 2025-09-30
WO2021183758A1 (en) 2021-09-16
HUE072784T2 (hu) 2025-12-28
AU2021232959A1 (en) 2022-09-15
ES3038279T3 (en) 2025-10-10
CN115461353B (zh) 2026-01-27
DK4118091T3 (da) 2025-08-18
ZA202209530B (en) 2024-02-28
HUE072382T2 (hu) 2025-11-28
WO2021183759A1 (en) 2021-09-16
US12295936B2 (en) 2025-05-13
CA3175087A1 (en) 2021-09-16
CN115461352A (zh) 2022-12-09
JP2023517673A (ja) 2023-04-26
JP7496427B2 (ja) 2024-06-06
EP4118091B1 (en) 2025-06-18
JP2023517674A (ja) 2023-04-26
US20210290591A1 (en) 2021-09-23
KR20220156570A (ko) 2022-11-25
AU2021233895B2 (en) 2026-04-02
TW202415385A (zh) 2024-04-16
NZ791481A (en) 2025-05-30
EP4118092B1 (en) 2025-07-16
EP4118091A1 (en) 2023-01-18
AR121554A1 (es) 2022-06-15
US20230390237A1 (en) 2023-12-07
EP4118092C0 (en) 2025-07-16
TWI830987B (zh) 2024-02-01
CN115461353A (zh) 2022-12-09
US20230137567A1 (en) 2023-05-04
CA3175114A1 (en) 2021-09-16
US20230136177A1 (en) 2023-05-04
TW202200158A (zh) 2022-01-01

Similar Documents

Publication Publication Date Title
JP1687679S (ja) コントローラー
JP1698267S (ja) コントローラー
EP4177501A4 (en) SLIDING COMPONENT
EP4107782A4 (en) MICROARRAYS
EP4160057A4 (en) SLIDING ELEMENT
HUE072194T2 (hu) Triazolil-metil-szubsztituált alfa-D-galaktopiranozid származékok
EP4160058A4 (en) Sliding component
PL4118092T3 (pl) Immunomodulujące o‑het‑arylowe azalidy
EP4177485A4 (en) SLIDING ELEMENT
JP1706136S (ja) コントローラ
EP4308572C0 (en) NEW THIENOPYRIMIDINONE DERIVATIVES
EP4063561C0 (en) REFINER SEGMENT
EP4394217A4 (en) SLIDING COMPONENT
EP4372253A4 (en) SLIDING ELEMENTS
EP4308576C0 (en) NEW THIAZOLOPYRIMIDINONE DERIVATIVES
EP4177487A4 (en) SLIDING COMPONENT
EP4151870A4 (en) SLIDING COMPONENT
DK4399216T3 (da) Immunmodulerende azalider
EP4394215A4 (en) SLIDING COMPONENT
EP4394216A4 (en) SLIDING COMPONENT
EP4394214A4 (en) SLIDING COMPONENT
EP4311082A4 (en) COMPONENT
EP4177486A4 (en) SLIDING ELEMENT
EP4130499A4 (en) SLIDING ELEMENT
EP3985472C0 (en) REGULATOR