PL4041713T3 - Postacie krystaliczne w stanie stałym selektywnego modulatora kanału potasowego - Google Patents

Postacie krystaliczne w stanie stałym selektywnego modulatora kanału potasowego

Info

Publication number
PL4041713T3
PL4041713T3 PL20800444.0T PL20800444T PL4041713T3 PL 4041713 T3 PL4041713 T3 PL 4041713T3 PL 20800444 T PL20800444 T PL 20800444T PL 4041713 T3 PL4041713 T3 PL 4041713T3
Authority
PL
Poland
Prior art keywords
solid state
crystalline forms
potassium channel
channel modulator
state crystalline
Prior art date
Application number
PL20800444.0T
Other languages
English (en)
Polish (pl)
Inventor
Paul Robert BICHLER
Jean-Jacques A. CADIEUX
Matthew David Tandy
Gregory N. Beatch
Original Assignee
Xenon Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenon Pharmaceuticals Inc. filed Critical Xenon Pharmaceuticals Inc.
Publication of PL4041713T3 publication Critical patent/PL4041713T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Liquid Crystal Substances (AREA)
  • Transmitters (AREA)
  • Laminated Bodies (AREA)
  • Medicinal Preparation (AREA)
PL20800444.0T 2019-10-10 2020-10-09 Postacie krystaliczne w stanie stałym selektywnego modulatora kanału potasowego PL4041713T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962913574P 2019-10-10 2019-10-10
PCT/US2020/055129 WO2021072307A1 (en) 2019-10-10 2020-10-09 Solid state crystalline forms of a selective potassium channel modulator

Publications (1)

Publication Number Publication Date
PL4041713T3 true PL4041713T3 (pl) 2025-04-14

Family

ID=73040296

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20800444.0T PL4041713T3 (pl) 2019-10-10 2020-10-09 Postacie krystaliczne w stanie stałym selektywnego modulatora kanału potasowego

Country Status (30)

Country Link
US (4) US11091441B2 (https=)
EP (2) EP4523687A3 (https=)
JP (1) JP2022552187A (https=)
KR (1) KR20220080119A (https=)
CN (4) CN119100981A (https=)
AU (1) AU2020364142A1 (https=)
BR (1) BR112022006583A2 (https=)
CA (1) CA3153752A1 (https=)
CL (1) CL2022000881A1 (https=)
CO (1) CO2022005890A2 (https=)
CR (1) CR20220187A (https=)
DK (1) DK4041713T3 (https=)
ES (1) ES3014703T3 (https=)
FI (1) FI4041713T3 (https=)
GE (2) GEP20247689B (https=)
HR (1) HRP20250134T1 (https=)
HU (1) HUE070295T2 (https=)
IL (2) IL292005B2 (https=)
LT (1) LT4041713T (https=)
MA (2) MA56288A1 (https=)
MX (3) MX2022004209A (https=)
PE (1) PE20221023A1 (https=)
PH (1) PH12022550854A1 (https=)
PL (1) PL4041713T3 (https=)
PT (1) PT4041713T (https=)
RS (1) RS66531B1 (https=)
SI (1) SI4041713T1 (https=)
SM (1) SMT202500101T1 (https=)
TW (1) TWI886158B (https=)
WO (1) WO2021072307A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI886158B (zh) * 2019-10-10 2025-06-11 加拿大商再諾製藥公司 選擇性鉀通道調節劑之固態晶型
MX2022005490A (es) 2019-11-08 2022-08-10 Xenon Pharmaceuticals Inc Metodos para el tratamiento de trastornos depresivos.
US11957675B2 (en) 2021-02-09 2024-04-16 Xenon Pharmaceuticals Inc. Methods and uses for treating anhedonia
CA3151863C (en) 2021-10-27 2024-01-02 Shanghai Zhimeng Biopharma, Inc. Compound as potassium channel regulator and preparation and use thereof
CN113698345B (zh) * 2021-10-27 2022-02-01 上海挚盟医药科技有限公司 作为钾通道调节剂的化合物及其制备和应用
CN120441482A (zh) * 2024-02-08 2025-08-08 上海挚盟医药科技有限公司 四氢异喹啉基化合物的晶型及其应用
WO2025179128A1 (en) 2024-02-22 2025-08-28 Xenon Pharmaceuticals Inc. Azetukalner for use in the treatment of depression, anhedonia or a seizure disorder such as epilepsy in pediatric subjects

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BR112022006583A2 (pt) 2022-06-28
PE20221023A1 (es) 2022-06-16
CN119100981A (zh) 2024-12-10
MA65149A1 (fr) 2026-03-31
MX2025010194A (es) 2025-10-01
CA3153752A1 (en) 2021-04-15
EP4523687A3 (en) 2025-05-21
SI4041713T1 (sl) 2025-07-31
HUE070295T2 (hu) 2025-05-28
ES3014703T3 (en) 2025-04-24
CN120157617A (zh) 2025-06-17
RS66531B1 (sr) 2025-03-31
IL292005A (en) 2022-06-01
US20220064120A1 (en) 2022-03-03
US20240279182A1 (en) 2024-08-22
SMT202500101T1 (it) 2025-05-12
IL292005B2 (en) 2025-05-01
IL292005B1 (en) 2025-01-01
CN120247795A (zh) 2025-07-04
EP4041713B1 (en) 2024-12-11
US11091441B2 (en) 2021-08-17
MX2022004209A (es) 2022-05-03
US20210147363A1 (en) 2021-05-20
KR20220080119A (ko) 2022-06-14
WO2021072307A1 (en) 2021-04-15
CO2022005890A2 (es) 2022-05-31
EP4041713B8 (en) 2025-01-15
AU2020364142A1 (en) 2022-04-21
CR20220187A (es) 2022-07-21
EP4523687A2 (en) 2025-03-19
MX2025010193A (es) 2025-10-01
EP4041713A1 (en) 2022-08-17
PH12022550854A1 (en) 2023-05-03
CL2022000881A1 (es) 2023-01-13
TW202128627A (zh) 2021-08-01
LT4041713T (lt) 2025-02-25
FI4041713T3 (fi) 2025-03-18
MA56288A1 (fr) 2023-01-31
PT4041713T (pt) 2025-02-25
TWI886158B (zh) 2025-06-11
DK4041713T3 (da) 2025-03-03
GEAP202415926A (en) 2024-07-10
IL316068A (en) 2024-12-01
CN115190874A (zh) 2022-10-14
JP2022552187A (ja) 2022-12-15
US12319657B1 (en) 2025-06-03
GEP20247689B (en) 2024-11-11
HRP20250134T1 (hr) 2025-03-28

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