PL3870233T3 - Koniugat paklitakselu z kwasem hialuronowym do leczenia raka pęcherza moczowego nienaciekającego mięśniówki - Google Patents

Koniugat paklitakselu z kwasem hialuronowym do leczenia raka pęcherza moczowego nienaciekającego mięśniówki

Info

Publication number
PL3870233T3
PL3870233T3 PL19801630.5T PL19801630T PL3870233T3 PL 3870233 T3 PL3870233 T3 PL 3870233T3 PL 19801630 T PL19801630 T PL 19801630T PL 3870233 T3 PL3870233 T3 PL 3870233T3
Authority
PL
Poland
Prior art keywords
paclitaxel
treatment
hyaluronic acid
bladder cancer
acid conjugate
Prior art date
Application number
PL19801630.5T
Other languages
English (en)
Inventor
Giorgio Mosconi
Daniela Jabes
Carlo PIZZOCARO
Original Assignee
Fidia Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici S.P.A. filed Critical Fidia Farmaceutici S.P.A.
Publication of PL3870233T3 publication Critical patent/PL3870233T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL19801630.5T 2018-10-25 2019-10-23 Koniugat paklitakselu z kwasem hialuronowym do leczenia raka pęcherza moczowego nienaciekającego mięśniówki PL3870233T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102018000009731A IT201800009731A1 (it) 2018-10-25 2018-10-25 Coniugato paclitaxel - acido ialuronico nel trattamento del carcinoma vescicale non infiltrante
PCT/IB2019/059073 WO2020084525A1 (en) 2018-10-25 2019-10-23 Paclitaxel-hyaluronic acid conjugate in the treatment of non-muscle invasive bladder cancer

Publications (1)

Publication Number Publication Date
PL3870233T3 true PL3870233T3 (pl) 2024-05-06

Family

ID=65324453

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19801630.5T PL3870233T3 (pl) 2018-10-25 2019-10-23 Koniugat paklitakselu z kwasem hialuronowym do leczenia raka pęcherza moczowego nienaciekającego mięśniówki

Country Status (21)

Country Link
US (4) US20200397909A1 (pl)
EP (1) EP3870233B1 (pl)
JP (1) JP7518815B2 (pl)
KR (1) KR102913965B1 (pl)
CN (2) CN112805035A (pl)
CA (1) CA3112188A1 (pl)
DK (1) DK3870233T3 (pl)
EA (1) EA202190614A1 (pl)
ES (1) ES2971217T3 (pl)
FI (1) FI3870233T3 (pl)
HR (1) HRP20240188T1 (pl)
HU (1) HUE066288T2 (pl)
IT (1) IT201800009731A1 (pl)
LT (1) LT3870233T (pl)
MA (1) MA63879B1 (pl)
PL (1) PL3870233T3 (pl)
PT (1) PT3870233T (pl)
RS (1) RS65193B1 (pl)
SI (1) SI3870233T1 (pl)
SM (1) SMT202400021T1 (pl)
WO (1) WO2020084525A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202000007747A1 (it) 2020-04-10 2021-10-10 Fidia Farm Spa Coniugato acido ialuronico-paclitaxel nel trattamento del mesotelioma
IT202000008209A1 (it) * 2020-04-17 2021-10-17 Fidia Farm Spa Procedimento di sintesi di un coniugato acido ialuronico-paclitaxel

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN163192B (pl) 1983-10-11 1988-08-20 Fidia Spa
IT1263393B (it) 1993-07-30 1996-08-05 Fidia Advanced Biopolymers Srl Processo per la preparazione e purificazione di acido ialuronico ad alto peso molecolare
NZ516873A (en) 2001-02-12 2003-11-28 Warner Lambert Co Compositions containing retinoids and erb inhibitors and their use in inhibiting retinoid skin damage
ITPD20020271A1 (it) * 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
US20050080075A1 (en) * 2003-08-25 2005-04-14 Nichols M. James Formulations, conjugates, and combinations of drugs for the treatment of neoplasms
ITMI20071267A1 (it) 2007-06-22 2008-12-23 Fidia Farmaceutici Uso di coniugati dell'acido ialuronico nel trattamento locale di malattie cutanee iperproliferative
IT1402385B1 (it) 2010-09-09 2013-09-04 Fidia Farmaceutici Processo per la produzione di acido ialuronico in escherichia coli o bacillus subtilis
IT1402384B1 (it) 2010-09-09 2013-09-04 Fidia Farmaceutici Processo per la produzione di acido ialuronico in escherichia coli o bacillus megaterium
ES3057718T3 (en) 2011-11-09 2026-03-04 Fibrobiologics Inc Fibroblasts for use in the treatment of degenerative disc disease
IT201600079633A1 (it) 2016-07-28 2018-01-28 Fidia Farm Spa Procedimento di preparazione e purificazione del sale sodico dell’acido ialuronico
CN110859962B (zh) 2019-11-25 2021-01-22 山东大学 巴比妥酸衍生物修饰的二硫化钼二维纳米材料及其应用

Also Published As

Publication number Publication date
EP3870233A1 (en) 2021-09-01
RS65193B1 (sr) 2024-03-29
WO2020084525A1 (en) 2020-04-30
MA63879B1 (fr) 2024-02-29
EP3870233B1 (en) 2023-12-06
IT201800009731A1 (it) 2020-04-25
US12465649B2 (en) 2025-11-11
US20200397909A1 (en) 2020-12-24
HUE066288T2 (hu) 2024-07-28
US20210268119A1 (en) 2021-09-02
US20210196833A1 (en) 2021-07-01
JP7518815B2 (ja) 2024-07-18
CA3112188A1 (en) 2020-04-30
JP2022503771A (ja) 2022-01-12
FI3870233T3 (fi) 2024-02-07
KR102913965B1 (ko) 2026-01-16
PT3870233T (pt) 2024-02-01
CN112805035A (zh) 2021-05-14
KR20210083249A (ko) 2021-07-06
US20240123077A1 (en) 2024-04-18
CN119792555A (zh) 2025-04-11
LT3870233T (lt) 2024-02-26
SI3870233T1 (sl) 2024-03-29
DK3870233T3 (da) 2024-02-05
SMT202400021T1 (it) 2024-03-13
ES2971217T3 (es) 2024-06-04
HRP20240188T1 (hr) 2024-05-10
EA202190614A1 (ru) 2021-06-03

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