PL3846903T3 - Bicykliczne pochodne heteroarylowe - Google Patents
Bicykliczne pochodne heteroaryloweInfo
- Publication number
- PL3846903T3 PL3846903T3 PL19759411.2T PL19759411T PL3846903T3 PL 3846903 T3 PL3846903 T3 PL 3846903T3 PL 19759411 T PL19759411 T PL 19759411T PL 3846903 T3 PL3846903 T3 PL 3846903T3
- Authority
- PL
- Poland
- Prior art keywords
- bicyclic heteroaryl
- heteroaryl derivatives
- derivatives
- bicyclic
- heteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18192219 | 2018-09-03 | ||
| PCT/EP2019/073303 WO2020048904A1 (en) | 2018-09-03 | 2019-09-02 | Bicyclic heteroaryl derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3846903T3 true PL3846903T3 (pl) | 2024-05-06 |
Family
ID=63490310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19759411.2T PL3846903T3 (pl) | 2018-09-03 | 2019-09-02 | Bicykliczne pochodne heteroarylowe |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US12084461B2 (pl) |
| EP (1) | EP3846903B1 (pl) |
| JP (1) | JP7398435B2 (pl) |
| KR (1) | KR102829709B1 (pl) |
| CN (1) | CN112566696B (pl) |
| AR (1) | AR116051A1 (pl) |
| AU (1) | AU2019336492B2 (pl) |
| BR (1) | BR112021002170A2 (pl) |
| CA (1) | CA3107593A1 (pl) |
| CL (1) | CL2021000486A1 (pl) |
| CO (1) | CO2021002415A2 (pl) |
| CR (1) | CR20210104A (pl) |
| DK (1) | DK3846903T3 (pl) |
| ES (1) | ES2966947T3 (pl) |
| FI (1) | FI3846903T3 (pl) |
| HR (1) | HRP20231663T1 (pl) |
| HU (1) | HUE064554T2 (pl) |
| IL (1) | IL281175B2 (pl) |
| LT (1) | LT3846903T (pl) |
| MA (1) | MA53541B1 (pl) |
| MX (1) | MX2021002087A (pl) |
| MY (1) | MY208133A (pl) |
| PE (1) | PE20210860A1 (pl) |
| PH (1) | PH12021550320A1 (pl) |
| PL (1) | PL3846903T3 (pl) |
| PT (1) | PT3846903T (pl) |
| RS (1) | RS64950B1 (pl) |
| SG (1) | SG11202102137SA (pl) |
| SI (1) | SI3846903T1 (pl) |
| TW (1) | TWI841592B (pl) |
| UA (1) | UA128482C2 (pl) |
| WO (1) | WO2020048904A1 (pl) |
| ZA (1) | ZA202007831B (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019412747B8 (en) | 2018-12-27 | 2025-04-24 | F. Hoffmann-La Roche Ag | Process for the preparation exo-tert-butyl N-(3-azabicyclo[3.2.1]octan-8-yl)carbamate |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994349A (en) | 1997-10-27 | 1999-11-30 | Howard University | 3-carboalkoxy-2, 3-dihydro-1H-phenothiazin-4[10H]-one derivatives |
| CN1217918C (zh) | 1998-04-01 | 2005-09-07 | 卡迪欧梅制药公司 | 氨基环己基醚化合物和其用途 |
| WO2000047547A2 (en) | 1999-02-12 | 2000-08-17 | Nortran Pharmaceuticals Inc. | Cycloalkyl amine compounds and uses thereof |
| US7507545B2 (en) | 1999-03-31 | 2009-03-24 | Cardiome Pharma Corp. | Ion channel modulating activity method |
| US6448246B1 (en) | 1999-05-25 | 2002-09-10 | Neurogen Corporation | Substituted 4H-1,4-benzothiazine-2-carboxamide: GABA brain receptor ligands |
| AU775102B2 (en) | 1999-09-13 | 2004-07-15 | David M. Swope | Composition and method for decreasing neurologic symptomatology |
| US7057053B2 (en) | 2000-10-06 | 2006-06-06 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
| WO2007032009A2 (en) | 2005-09-15 | 2007-03-22 | Biomas Ltd. | Use of tellurium compounds for treatment of basal cell carcinoma and/or actinic keratosis |
| CN101675045B (zh) | 2007-05-11 | 2012-11-28 | 弗·哈夫曼-拉罗切有限公司 | 作为β-淀粉样蛋白调节剂的杂芳基苯胺 |
| ATE543799T1 (de) | 2007-10-19 | 2012-02-15 | Janssen Pharmaceutica Nv | Piperidinyl- und piperazinylmodulatoren von g- sekretase |
| JP5503663B2 (ja) | 2008-11-13 | 2014-05-28 | メルク・シャープ・アンド・ドーム・コーポレーション | ガンマセクレターゼモジュレータ |
| RU2515976C2 (ru) | 2009-02-26 | 2014-05-20 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Азотсодержащие конденсированные гетероциклические соединения и их применение в качестве ингибиторов продукции бета-амилоида |
| WO2010138901A1 (en) | 2009-05-29 | 2010-12-02 | Biogen Idec Ma Inc | Carboxylic acid-containing compounds, derivatives thereof, and related methods of use |
| US20120142672A1 (en) * | 2009-07-13 | 2012-06-07 | Tatsuki Koike | Heterocyclic compound and use thereof |
| KR20120046327A (ko) | 2009-09-04 | 2012-05-09 | 휴렛-팩커드 디벨롭먼트 컴퍼니, 엘.피. | 혼합된-금속-원자가 화합물에 기초한 멤리스터 |
| US20110190269A1 (en) | 2010-02-01 | 2011-08-04 | Karlheinz Baumann | Gamma secretase modulators |
| US8486967B2 (en) * | 2010-02-17 | 2013-07-16 | Hoffmann-La Roche Inc. | Heteroaryl substituted piperidines |
| US8703763B2 (en) | 2011-03-02 | 2014-04-22 | Hoffmann-La Roche Inc. | Bridged piperidine derivatives |
| CN103874702B (zh) * | 2011-07-15 | 2015-12-09 | 杨森制药公司 | 作为γ分泌酶调节剂的经取代的吲哚衍生物 |
| WO2014060112A1 (en) | 2012-10-19 | 2014-04-24 | Origenis Gmbh | Pyrazolo[4,3-d]pyrimidines as kinase inhibitors |
| WO2017042114A1 (en) | 2015-09-09 | 2017-03-16 | F. Hoffmann-La Roche Ag | Bridged piperidine derivatives |
| EP3386978B1 (en) | 2015-12-10 | 2021-01-27 | H. Hoffnabb-La Roche Ag | Bridged piperidine derivatives |
| CN109311878B (zh) | 2016-06-27 | 2022-05-24 | 豪夫迈·罗氏有限公司 | 作为γ-分泌酶调节剂的三唑并吡啶类化合物 |
| AR109829A1 (es) | 2016-09-29 | 2019-01-30 | Hoffmann La Roche | Derivados de piperidina puenteados |
| EP3535266B1 (en) | 2016-11-01 | 2021-12-29 | F. Hoffmann-La Roche AG | Bicyclic heteroaryl derivatives |
| US11319314B2 (en) | 2016-11-08 | 2022-05-03 | Hoffmann-La Roche Inc. | Phenoxytriazoles |
| EP3554502A4 (en) | 2016-12-16 | 2021-01-06 | Pipeline Therapeutics, Inc. | METHOD FOR TREATMENT OF COCHLEA SYNAPTOPATHY |
| US11370802B2 (en) | 2018-01-22 | 2022-06-28 | Hoffmann-La Roche, Inc. | Triazolo-azepine derivatives |
-
2019
- 2019-09-02 MX MX2021002087A patent/MX2021002087A/es unknown
- 2019-09-02 AR ARP190102494A patent/AR116051A1/es unknown
- 2019-09-02 KR KR1020217006240A patent/KR102829709B1/ko active Active
- 2019-09-02 HU HUE19759411A patent/HUE064554T2/hu unknown
- 2019-09-02 PL PL19759411.2T patent/PL3846903T3/pl unknown
- 2019-09-02 PT PT197594112T patent/PT3846903T/pt unknown
- 2019-09-02 PE PE2021000165A patent/PE20210860A1/es unknown
- 2019-09-02 BR BR112021002170-1A patent/BR112021002170A2/pt unknown
- 2019-09-02 UA UAA202101190A patent/UA128482C2/uk unknown
- 2019-09-02 CA CA3107593A patent/CA3107593A1/en active Pending
- 2019-09-02 RS RS20231189A patent/RS64950B1/sr unknown
- 2019-09-02 SI SI201930682T patent/SI3846903T1/sl unknown
- 2019-09-02 SG SG11202102137SA patent/SG11202102137SA/en unknown
- 2019-09-02 IL IL281175A patent/IL281175B2/en unknown
- 2019-09-02 WO PCT/EP2019/073303 patent/WO2020048904A1/en not_active Ceased
- 2019-09-02 US US17/273,278 patent/US12084461B2/en active Active
- 2019-09-02 DK DK19759411.2T patent/DK3846903T3/da active
- 2019-09-02 MY MYPI2021001098A patent/MY208133A/en unknown
- 2019-09-02 EP EP19759411.2A patent/EP3846903B1/en active Active
- 2019-09-02 MA MA53541A patent/MA53541B1/fr unknown
- 2019-09-02 FI FIEP19759411.2T patent/FI3846903T3/fi active
- 2019-09-02 CN CN201980054254.2A patent/CN112566696B/zh active Active
- 2019-09-02 LT LTEPPCT/EP2019/073303T patent/LT3846903T/lt unknown
- 2019-09-02 HR HRP20231663TT patent/HRP20231663T1/hr unknown
- 2019-09-02 AU AU2019336492A patent/AU2019336492B2/en active Active
- 2019-09-02 JP JP2021512272A patent/JP7398435B2/ja active Active
- 2019-09-02 ES ES19759411T patent/ES2966947T3/es active Active
- 2019-09-02 TW TW108131458A patent/TWI841592B/zh active
- 2019-09-02 CR CR20210104A patent/CR20210104A/es unknown
-
2020
- 2020-12-15 ZA ZA2020/07831A patent/ZA202007831B/en unknown
-
2021
- 2021-02-15 PH PH12021550320A patent/PH12021550320A1/en unknown
- 2021-02-24 CO CONC2021/0002415A patent/CO2021002415A2/es unknown
- 2021-02-26 CL CL2021000486A patent/CL2021000486A1/es unknown
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