PL378560A1 - Sposób wytwarzania glimepirydu i odpowiedni związek wyjściowy - Google Patents

Sposób wytwarzania glimepirydu i odpowiedni związek wyjściowy

Info

Publication number
PL378560A1
PL378560A1 PL378560A PL37856004A PL378560A1 PL 378560 A1 PL378560 A1 PL 378560A1 PL 378560 A PL378560 A PL 378560A PL 37856004 A PL37856004 A PL 37856004A PL 378560 A1 PL378560 A1 PL 378560A1
Authority
PL
Poland
Prior art keywords
glimepiride
manufacturing
respective intermediate
manufacturing glimepiride
Prior art date
Application number
PL378560A
Other languages
English (en)
Inventor
Stanislav Radl
Kamal Jarrah
Original Assignee
Zentiva, A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentiva, A.S. filed Critical Zentiva, A.S.
Publication of PL378560A1 publication Critical patent/PL378560A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/382-Pyrrolones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL378560A 2003-02-21 2004-02-20 Sposób wytwarzania glimepirydu i odpowiedni związek wyjściowy PL378560A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ2003530A CZ293789B6 (cs) 2003-02-21 2003-02-21 Způsob výroby glimepiridu a příslušný meziprodukt

Publications (1)

Publication Number Publication Date
PL378560A1 true PL378560A1 (pl) 2006-05-02

Family

ID=32602129

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378560A PL378560A1 (pl) 2003-02-21 2004-02-20 Sposób wytwarzania glimepirydu i odpowiedni związek wyjściowy

Country Status (9)

Country Link
US (1) US7282517B2 (pl)
EP (1) EP1594839A2 (pl)
JP (1) JP2006522019A (pl)
CA (1) CA2515520A1 (pl)
CZ (1) CZ293789B6 (pl)
EA (1) EA008193B1 (pl)
PL (1) PL378560A1 (pl)
SK (1) SK50692005A3 (pl)
WO (1) WO2004073585A2 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070116778A (ko) * 2005-04-01 2007-12-11 유에스브이 리미티드 실질적으로 순수한 글리메피리드의 신규한 제조방법
CN103601661B (zh) * 2013-09-22 2015-10-21 江苏德峰药业有限公司 Ⅱ型糖尿病药物格列美脲三光气的合成方法
CN103508932B (zh) * 2013-09-22 2015-06-10 江苏德峰药业有限公司 糖尿病药物格列美脲的合成方法
CN106866487A (zh) * 2017-02-08 2017-06-20 深圳市新阳唯康科技有限公司 一种格列美脲ε晶型及其制备方法
CN106883161A (zh) * 2017-02-08 2017-06-23 深圳市新阳唯康科技有限公司 一种格列美脲β晶型及其制备方法
CN106866485A (zh) * 2017-02-08 2017-06-20 深圳市新阳唯康科技有限公司 一种格列美脲δ晶型及其制备方法
CN106866486A (zh) * 2017-02-08 2017-06-20 深圳市新阳唯康科技有限公司 一种格列美脲α晶型及其制备方法
CN106699631A (zh) * 2017-02-08 2017-05-24 深圳市新阳唯康科技有限公司 一种格列美脲γ晶型及其制备方法
CN112028807A (zh) * 2020-08-07 2020-12-04 重庆康刻尔制药股份有限公司 一种格列美脲原料药的精制方法
CN114264765B (zh) * 2020-09-16 2023-10-03 徐州万邦金桥制药有限公司 一种利用hplc测定格列美脲中间体中有关物质的分析方法
CN114839286B (zh) * 2022-04-26 2023-05-30 北京悦康科创医药科技股份有限公司 一种格列美脲原料药中有关物质的测定方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2951135A1 (de) * 1979-12-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung

Also Published As

Publication number Publication date
EA200501321A1 (ru) 2006-02-24
WO2004073585A2 (en) 2004-09-02
SK50692005A3 (sk) 2005-11-03
CZ2003530A3 (cs) 2004-07-14
US20070054954A1 (en) 2007-03-08
WO2004073585A3 (en) 2004-10-14
EA008193B1 (ru) 2007-04-27
JP2006522019A (ja) 2006-09-28
CA2515520A1 (en) 2004-09-02
CZ293789B6 (cs) 2004-07-14
EP1594839A2 (en) 2005-11-16
US7282517B2 (en) 2007-10-16

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)