PL3774897T3 - Sposoby i układ do selekcji i leczenia pacjentów z chorobami zapalnymi - Google Patents

Sposoby i układ do selekcji i leczenia pacjentów z chorobami zapalnymi

Info

Publication number
PL3774897T3
PL3774897T3 PL19796203.8T PL19796203T PL3774897T3 PL 3774897 T3 PL3774897 T3 PL 3774897T3 PL 19796203 T PL19796203 T PL 19796203T PL 3774897 T3 PL3774897 T3 PL 3774897T3
Authority
PL
Poland
Prior art keywords
selecting
methods
inflammatory diseases
treating patients
patients
Prior art date
Application number
PL19796203.8T
Other languages
English (en)
Inventor
Janine Bilsborough
Dermot P. Mcgovern
Stephan Targan
Alka POTDAR
Jeffry D. Watkins
Cindy T. DICKERSON
Original Assignee
Cedars-Sinai Medical Center
Prometheus Biosciences, Inc.
Dr. Falk Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cedars-Sinai Medical Center, Prometheus Biosciences, Inc., Dr. Falk Pharma Gmbh filed Critical Cedars-Sinai Medical Center
Publication of PL3774897T3 publication Critical patent/PL3774897T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
PL19796203.8T 2018-04-30 2019-04-26 Sposoby i układ do selekcji i leczenia pacjentów z chorobami zapalnymi PL3774897T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862664720P 2018-04-30 2018-04-30
US201862681557P 2018-06-06 2018-06-06
US201862784179P 2018-12-21 2018-12-21
PCT/US2019/029402 WO2019212899A1 (en) 2018-04-30 2019-04-26 Methods and systems for selection and treatment of patients with inflammatory diseases

Publications (1)

Publication Number Publication Date
PL3774897T3 true PL3774897T3 (pl) 2024-01-29

Family

ID=68386125

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19796203.8T PL3774897T3 (pl) 2018-04-30 2019-04-26 Sposoby i układ do selekcji i leczenia pacjentów z chorobami zapalnymi

Country Status (21)

Country Link
US (2) US12305236B2 (pl)
EP (2) EP4296285A3 (pl)
JP (2) JP2021532060A (pl)
KR (2) KR20250111409A (pl)
CN (1) CN112368301B (pl)
AU (1) AU2019261933B2 (pl)
CA (1) CA3098720A1 (pl)
DK (1) DK3774897T5 (pl)
ES (1) ES2962715T3 (pl)
FI (1) FI3774897T3 (pl)
HR (1) HRP20231367T1 (pl)
HU (1) HUE063908T2 (pl)
LT (1) LT3774897T (pl)
MA (1) MA52251A (pl)
MD (1) MD3774897T2 (pl)
PL (1) PL3774897T3 (pl)
PT (1) PT3774897T (pl)
RS (1) RS64747B1 (pl)
SI (1) SI3774897T1 (pl)
TW (1) TW202003573A (pl)
WO (1) WO2019212899A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104114577A (zh) 2011-09-30 2014-10-22 特瓦制药澳大利亚私人有限公司 针对TL1a的抗体及其用途
TWI703158B (zh) 2015-09-18 2020-09-01 美商希佛隆公司 特異性結合tl1a之抗體
RS64747B1 (sr) 2018-04-30 2023-11-30 Cedars Sinai Medical Center Postupci i sistemi za odabir i lečenje pacijenata sa inflamatornim bolestima
WO2020112890A1 (en) 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Rnaset2 compositions and methods of treatment therewith
MA54903A (fr) * 2019-02-08 2021-12-15 Cedars Sinai Medical Center Méthodes, compositions et kits pour traiter une maladie inflammatoire ciblant il18r1
BR112021022789A2 (pt) 2019-05-14 2022-04-19 Cedars Sinai Medical Center Métodos, sistemas e dispositivos para a seleção de pacientes para tl1a
MX2023005688A (es) * 2020-11-13 2023-07-18 Prometheus Biosciences Inc Metodos, sistemas y equipos para el tratamiento de enfermedades inflamatorias dirigidas al tl1a.
CA3200256A1 (en) * 2020-12-01 2022-06-09 Rebecca GONSKY Methods and systems of stratifying inflammatory disease patients
CN117255802A (zh) * 2021-02-17 2023-12-19 普罗米修斯生物科学公司 抗cd30l抗体和其用途
AR130041A1 (es) * 2022-07-27 2024-10-30 Cephalon Llc Formulaciones de anticuerpos anti-tl1a
AU2023314783A1 (en) * 2022-07-27 2025-03-06 Cephalon Llc Anti-tl1a antibodies for the treatment of ulcerative colitis and crohn's disease
WO2024143497A1 (ja) * 2022-12-28 2024-07-04 国立大学法人京都大学 Cd153を標的とする医薬組成物
AU2024324300A1 (en) 2023-08-11 2026-02-12 Paragon Therapeutics, Inc. Tl1a binding antibodies and methods of use

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US4229447A (en) 1979-06-04 1980-10-21 American Home Products Corporation Intraoral methods of using benzodiazepines
US5116817A (en) 1982-12-10 1992-05-26 Syntex (U.S.A.) Inc. LHRH preparations for intranasal administration
US4476116A (en) 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
US4596795A (en) 1984-04-25 1986-06-24 The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
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US5739136A (en) 1989-10-17 1998-04-14 Ellinwood, Jr.; Everett H. Intraoral dosing method of administering medicaments
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US6960563B2 (en) 2001-08-31 2005-11-01 Morton Grove Pharmaceuticals, Inc. Spontaneous emulsions containing cyclosporine
US20060194265A1 (en) * 2001-10-23 2006-08-31 Morris David W Novel therapeutic targets in cancer
DK1667730T3 (da) 2003-08-20 2013-09-23 Univ Miami Sammensætninger og fremgangsmåder til behandling af inflammatorisk lungesygdom
US20100190162A1 (en) 2007-02-26 2010-07-29 Cedars-Sinai Medical Center Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease
SG172988A1 (en) * 2009-03-27 2011-08-29 Merck Serono Sa Genetic severity markers in multiple sclerosis
EP2451802A1 (en) 2009-07-07 2012-05-16 Pathway Therapeutics, Inc. Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy
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CN113416257A (zh) 2011-11-30 2021-09-21 中外制药株式会社 包含进入细胞内以形成免疫复合体的搬运体(载体)的药物
LT3431492T (lt) * 2012-04-27 2021-04-26 Novo Nordisk A/S Žmogaus cd30 ligandą-antigeną surišantys baltymai
AU2013271336B2 (en) 2012-06-04 2017-11-30 Centre For Digestive Diseases Compositions and methods for treating Crohn's Disease and related conditions and infections
EP3389781B1 (en) 2015-12-15 2021-08-11 University of Miami Inhibitors of tnf superfamily costimulatory interactions and methods for uses of the same
CN110121509B (zh) 2016-10-26 2024-05-07 西达-赛奈医疗中心 中和抗tl1a单克隆抗体
RS64747B1 (sr) 2018-04-30 2023-11-30 Cedars Sinai Medical Center Postupci i sistemi za odabir i lečenje pacijenata sa inflamatornim bolestima

Also Published As

Publication number Publication date
DK3774897T3 (da) 2023-11-06
EP4296285A3 (en) 2024-02-28
TW202003573A (zh) 2020-01-16
KR20210013062A (ko) 2021-02-03
WO2019212899A1 (en) 2019-11-07
EP3774897A4 (en) 2022-02-16
CN112368301B (zh) 2025-12-02
EP3774897B1 (en) 2023-09-27
AU2019261933B2 (en) 2025-12-18
ES2962715T3 (es) 2024-03-20
AU2019261933A1 (en) 2020-12-03
JP2024133462A (ja) 2024-10-02
KR20250111409A (ko) 2025-07-22
RS64747B1 (sr) 2023-11-30
CA3098720A1 (en) 2019-11-07
PT3774897T (pt) 2023-11-10
US20210238684A1 (en) 2021-08-05
JP7832987B2 (ja) 2026-03-18
US12305236B2 (en) 2025-05-20
EP4296285A2 (en) 2023-12-27
MA52251A (fr) 2021-02-17
EP3774897A1 (en) 2021-02-17
JP2021532060A (ja) 2021-11-25
FI3774897T3 (fi) 2023-11-03
HUE063908T2 (hu) 2024-02-28
CN112368301A (zh) 2021-02-12
US20250290143A1 (en) 2025-09-18
DK3774897T5 (da) 2024-08-19
HRP20231367T1 (hr) 2024-02-16
LT3774897T (lt) 2023-11-10
MD3774897T2 (ro) 2024-02-29
SI3774897T1 (sl) 2024-01-31

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