PL377320A1 - Pochodne indolilowe - Google Patents

Pochodne indolilowe

Info

Publication number
PL377320A1
PL377320A1 PL377320A PL37732003A PL377320A1 PL 377320 A1 PL377320 A1 PL 377320A1 PL 377320 A PL377320 A PL 377320A PL 37732003 A PL37732003 A PL 37732003A PL 377320 A1 PL377320 A1 PL 377320A1
Authority
PL
Poland
Prior art keywords
indolyl derivatives
indolyl
derivatives
Prior art date
Application number
PL377320A
Other languages
English (en)
Inventor
Alfred Binggeli
Uwe Grether
Hans Hilpert
Georges Hirth
Bernd Kuhn
Hans-Peter Maerki
Markus Meyer
Peter Mohr
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL377320A1 publication Critical patent/PL377320A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL377320A 2002-11-25 2003-11-17 Pochodne indolilowe PL377320A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02026366 2002-11-25

Publications (1)

Publication Number Publication Date
PL377320A1 true PL377320A1 (pl) 2006-01-23

Family

ID=32338000

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377320A PL377320A1 (pl) 2002-11-25 2003-11-17 Pochodne indolilowe

Country Status (21)

Country Link
US (1) US7098228B2 (pl)
EP (1) EP1567523B1 (pl)
JP (1) JP4384052B2 (pl)
KR (1) KR100713266B1 (pl)
CN (1) CN100343250C (pl)
AR (1) AR042117A1 (pl)
AT (1) ATE405560T1 (pl)
AU (1) AU2003292030B2 (pl)
BR (1) BR0316556A (pl)
CA (1) CA2505545C (pl)
DE (1) DE60323130D1 (pl)
ES (1) ES2312819T3 (pl)
GT (1) GT200300251A (pl)
MX (1) MXPA05005445A (pl)
PA (1) PA8589401A1 (pl)
PE (1) PE20040843A1 (pl)
PL (1) PL377320A1 (pl)
RU (1) RU2315767C2 (pl)
TW (1) TW200413357A (pl)
UY (1) UY28091A1 (pl)
WO (1) WO2004048371A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050203151A1 (en) * 2003-12-19 2005-09-15 Kalypsys, Inc. Novel compounds, compositions and uses thereof for treatment of metabolic disorders and related conditions
WO2008098857A1 (en) * 2007-02-15 2008-08-21 F. Hoffmann-La Roche Ag 2-aminooxazolines as taar1 ligands

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011326A (en) * 1975-07-29 1977-03-08 Merck & Co., Inc. 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents
DE3034005C2 (de) 1980-09-10 1982-12-09 A. Nattermann & Cie GmbH, 5000 Köln Indolessigsäure-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
CA1247547A (en) * 1983-06-22 1988-12-28 Paul Hadvary Leucine derivatives
CA1328881C (en) 1984-12-21 1994-04-26 Pierre Barbier Process for the manufacture of oxetanones
CA1270837A (en) 1984-12-21 1990-06-26 Hoffmann-La Roche Limited Oxetanones
CA2035972C (en) 1990-02-23 2006-07-11 Martin Karpf Process for the preparation of oxetanones
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
US5274143A (en) 1991-07-23 1993-12-28 Hoffmann-La Roche Inc. Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione
PL176885B1 (pl) 1992-07-03 1999-08-31 Smithkline Beecham Plc Kompozycja farmaceutyczna
GB9225386D0 (en) 1992-12-04 1993-01-27 Smithkline Beecham Plc Novel compounds
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
GB9326171D0 (en) 1993-12-22 1994-02-23 Smithkline Beecham Plc Novel compounds
JPH09176162A (ja) * 1995-12-22 1997-07-08 Toubishi Yakuhin Kogyo Kk チアゾリジンジオン誘導体及びその製造法並びにそれを含む医薬組成物
GB9600464D0 (en) 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
EP0914321B1 (en) * 1996-07-09 2004-09-22 Nikem Research S.R.L. Indole derivatives for the treatment of osteoporosis
WO1998025606A1 (en) * 1996-12-10 1998-06-18 Bristol-Myers Squibb Company Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agents
US6004996A (en) * 1997-02-05 1999-12-21 Hoffman-La Roche Inc. Tetrahydrolipstatin containing compositions
DE19711616A1 (de) * 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
US6121397A (en) * 1997-07-14 2000-09-19 Xerox Corporation Polymerization processes using oligomeric compound, monomer and surfactant
HN1998000118A (es) 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.
EP0903343B1 (en) 1997-09-19 2003-05-28 SSP Co., Ltd. Alpha-Substituted phenylpropionic acid derivative and medicine containing the same
DE69828445D1 (de) 1998-04-23 2005-02-03 Reddys Lab Ltd Dr Heterozyklische verbindungen,und deren verwendung in arzneimittel,verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
GB9817118D0 (en) 1998-08-07 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds
CN1152680C (zh) 1998-08-14 2004-06-09 霍夫曼-拉罗奇有限公司 含有脂酶抑制剂和壳聚糖的药物组合物
ATE293970T1 (de) 1998-08-14 2005-05-15 Hoffmann La Roche Lipasehemmer enthaltende pharmazeutische zusammensetzungen
GB9902459D0 (en) * 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9914977D0 (en) 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
ES2258431T3 (es) * 1999-08-02 2006-09-01 F. Hoffmann-La Roche Ag Proceso para la preparacion de derivados de benzotiofeno.
JP2004501863A (ja) * 2000-01-19 2004-01-22 アルテオン　インコーポレーテッド チアゾール、イミダゾールおよびオキサゾール化合物、ならびにタンパク質老化関連疾患の治療
CA2418104A1 (en) 2000-08-23 2002-02-28 Eli Lilly And Company Oxazolyl-arylpropionic acid derivatives and their use as ppar agonists
US6949566B2 (en) * 2000-09-29 2005-09-27 Shionogi & Co. Ltd. Thiazole and oxazole derivatives
SI1392295T1 (sl) * 2001-05-15 2006-10-31 Hoffmann La Roche Derivati oksazola, substituirani s karboksilno kislino, za uporabo kot ppar -alfa in -gama aktivatorji pri zdravljenju diabetesa
WO2003004458A1 (en) 2001-07-03 2003-01-16 Biovitrum Ab New compounds
US6903104B2 (en) * 2001-12-06 2005-06-07 National Health Research Institutes Indol-3-YL-2-oxoacetamide compounds and methods of use thereof
TWI317634B (en) * 2001-12-13 2009-12-01 Nat Health Research Institutes Aroyl indoles compounds
WO2003053976A1 (en) 2001-12-20 2003-07-03 Biovitrum Ab PIPAZOLO [1,5-a] PYRIMIDINE DERIVATIVES AS MODULATORS OF PPAR

Also Published As

Publication number Publication date
WO2004048371A1 (en) 2004-06-10
AU2003292030A1 (en) 2004-06-18
DE60323130D1 (de) 2008-10-02
MXPA05005445A (es) 2005-08-26
EP1567523B1 (en) 2008-08-20
PA8589401A1 (es) 2004-07-20
US7098228B2 (en) 2006-08-29
EP1567523A1 (en) 2005-08-31
CA2505545A1 (en) 2004-06-10
ATE405560T1 (de) 2008-09-15
RU2315767C2 (ru) 2008-01-27
UY28091A1 (es) 2004-05-31
CN1717407A (zh) 2006-01-04
JP2006513173A (ja) 2006-04-20
KR100713266B1 (ko) 2007-05-04
JP4384052B2 (ja) 2009-12-16
CN100343250C (zh) 2007-10-17
KR20050086759A (ko) 2005-08-30
TW200413357A (en) 2004-08-01
AU2003292030B2 (en) 2007-01-04
BR0316556A (pt) 2005-10-04
CA2505545C (en) 2011-06-07
ES2312819T3 (es) 2009-03-01
GT200300251A (es) 2004-06-28
US20040106657A1 (en) 2004-06-03
PE20040843A1 (es) 2004-12-24
AR042117A1 (es) 2005-06-08
RU2005120152A (ru) 2006-05-27

Similar Documents

Publication Publication Date Title
AP1850A (en) Spiroindolineplperidine derivatives
EG24050A (en) Heterocylocarboxamide derivatives
HK1077068A1 (en) Azolidinone-vinyl fused-benzene derivatives
IL166121A0 (en) Indole-3-sulphur derivatives
EP1522540A4 (en) AZAARENE DERIVATIVES
IL163892A0 (en) Indolylmaleimide derivatives
PL376475A1 (pl) Pochodne N-podstawionej 2-oksodihydropirydyny
ZA200500471B (en) N-biarylmethyl aminocycloalkanecarboxamide derivatives
PL375111A1 (pl) Nowe podstawione indole
GB0317665D0 (en) Qinazoline derivatives
IL166404A0 (en) Indoline derivatives substituted in
IL165572A0 (en) 1-Ä(indoÜ-3-yl)carbonylÜpiperazine derivatives
AU2003222659A8 (en) 23-o-substituted 5-o-mycaminosyltylonide derivatives
GB0227259D0 (en) Porphyrin derivatives
HK1069579A1 (en) Novel indole derivatives
EP1531854A4 (en) O-DERIVATED NOCATHIACIN DERIVATIVES
GB0319793D0 (en) Pyridinylmorpholine derivatives
GB0213488D0 (en) 2-Naphthamide derivatives
PL377320A1 (pl) Pochodne indolilowe
AU2003243397A8 (en) Homo-camptothecin derivatives
GB0219894D0 (en) Dihydropyridinone derivatives
GB0210512D0 (en) Tetrahydro-napthalene derivatives
AU2003285777A8 (en) 3-substituted-4-pyrimidone derivatives
GB0119696D0 (en) Indole derivatives
GB0119820D0 (en) Indole derivatives

Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)