PL376346A1 - Agoniści adrenoreceptora alfa 2B lub 2B/2C do leczenia neurodegeneracji - Google Patents
Agoniści adrenoreceptora alfa 2B lub 2B/2C do leczenia neurodegeneracjiInfo
- Publication number
- PL376346A1 PL376346A1 PL03376346A PL37634603A PL376346A1 PL 376346 A1 PL376346 A1 PL 376346A1 PL 03376346 A PL03376346 A PL 03376346A PL 37634603 A PL37634603 A PL 37634603A PL 376346 A1 PL376346 A1 PL 376346A1
- Authority
- PL
- Poland
- Prior art keywords
- alpha
- neurodegeneration
- treatment
- adrenoceptor agonists
- disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41704902P | 2002-10-08 | 2002-10-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
PL376346A1 true PL376346A1 (pl) | 2005-12-27 |
PL216373B1 PL216373B1 (pl) | 2014-03-31 |
Family
ID=32093954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL376346A PL216373B1 (pl) | 2002-10-08 | 2003-10-07 | Zastosowanie selektywnego agonisty receptora α 2B adrenergicznego lub α 2B/2C adrenergicznego |
Country Status (20)
Country | Link |
---|---|
US (1) | US20040138312A1 (pl) |
EP (1) | EP1549305B1 (pl) |
JP (2) | JP4724421B2 (pl) |
KR (1) | KR20050050124A (pl) |
CN (1) | CN100431536C (pl) |
AT (1) | ATE429216T1 (pl) |
AU (2) | AU2003282758A1 (pl) |
BR (1) | BR0314540A (pl) |
CA (1) | CA2501347A1 (pl) |
DE (1) | DE60327335D1 (pl) |
ES (1) | ES2322954T3 (pl) |
HK (1) | HK1081880A1 (pl) |
IL (1) | IL167849A (pl) |
MX (1) | MXPA05003664A (pl) |
NO (1) | NO20051663L (pl) |
NZ (1) | NZ539328A (pl) |
PL (1) | PL216373B1 (pl) |
RU (1) | RU2330649C2 (pl) |
WO (1) | WO2004032913A1 (pl) |
ZA (1) | ZA200502744B (pl) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2007206A4 (en) * | 2006-03-16 | 2010-12-08 | Yeda Res & Dev | METHOD AND COMPOSITION FOR THE PROTECTION OF NEURONAL TISSUE FROM DEGATES INDUCED BY HIGH LEVELS OF GLUTAMATE |
US20100216857A1 (en) * | 2007-10-18 | 2010-08-26 | Luhrs Lauren M B | Method of treating motor disorders with 4-(1-(2,3-dimethylphenyl)ethyl)-1h-imidazole-2(3h)-thione |
WO2009052075A2 (en) * | 2007-10-18 | 2009-04-23 | Allergan, Inc. | Method of treating motor disorders with alpha-2b adrenergic receptor agonists |
WO2009052073A2 (en) * | 2007-10-18 | 2009-04-23 | Allergan, Inc. | Method of treating sensorimotor disorders with alpha-2 adrenergic receptor agonists |
AU2009333620A1 (en) * | 2008-12-08 | 2011-07-07 | Allergan, Inc. | N-(1-phenyl-2-arylethyl)-4,5-dihydro-3H-pyrrol-2-amine compounds as subtype selective modulators of alpha2B or alpha2B and alpha2C adrenoceptors |
JP6868698B2 (ja) | 2016-12-31 | 2021-05-12 | バイオエクセル セラピューティクス,インコーポレイテッド | 激越の治療のための舌下デクスメデトミジンの使用 |
MX2020014000A (es) | 2018-06-27 | 2021-06-15 | Bioxcel Therapeutics Inc | Formulaciones en lámina que contienen dexmedetomidina y métodos para producirlas. |
BR112022000992A2 (pt) | 2019-07-19 | 2022-06-14 | Arx Llc | Regimes de tratamento de dexmedetomidina não sedantes |
US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4029792A (en) * | 1972-02-29 | 1977-06-14 | Pfizer Inc. | (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents |
BE795970A (fr) * | 1972-02-29 | 1973-08-27 | Pfizer | Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant |
US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
US6194415B1 (en) * | 1995-06-28 | 2001-02-27 | Allergan Sales, Inc. | Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury |
NZ504667A (en) * | 1997-12-04 | 2003-03-28 | Allergan Sales Inc | Substituted imidazole derivatives having agonist-like activity at alpha 2B or 2B/2C adrenergic receptors |
US6329369B1 (en) * | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
US6841684B2 (en) * | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
BR0109317A (pt) * | 2000-07-14 | 2003-06-17 | Allergan Inc | Composições contendo componentes agonistas alfa-2-adrenérgicos |
AU2002248284A1 (en) * | 2000-11-01 | 2002-08-06 | Allergan, Inc. | Compositions for treatment of ocular neovascularization |
US7091232B2 (en) * | 2002-05-21 | 2006-08-15 | Allergan, Inc. | 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds |
-
2003
- 2003-10-07 DE DE60327335T patent/DE60327335D1/de not_active Expired - Lifetime
- 2003-10-07 JP JP2004543495A patent/JP4724421B2/ja not_active Expired - Fee Related
- 2003-10-07 BR BR0314540-9A patent/BR0314540A/pt not_active Application Discontinuation
- 2003-10-07 KR KR1020057006114A patent/KR20050050124A/ko active IP Right Grant
- 2003-10-07 RU RU2005114504/14A patent/RU2330649C2/ru not_active IP Right Cessation
- 2003-10-07 ES ES03774642T patent/ES2322954T3/es not_active Expired - Lifetime
- 2003-10-07 CA CA002501347A patent/CA2501347A1/en not_active Abandoned
- 2003-10-07 EP EP03774642A patent/EP1549305B1/en not_active Expired - Lifetime
- 2003-10-07 PL PL376346A patent/PL216373B1/pl unknown
- 2003-10-07 NZ NZ539328A patent/NZ539328A/en not_active IP Right Cessation
- 2003-10-07 US US10/680,879 patent/US20040138312A1/en not_active Abandoned
- 2003-10-07 CN CNB200380101115XA patent/CN100431536C/zh not_active Expired - Fee Related
- 2003-10-07 WO PCT/US2003/031809 patent/WO2004032913A1/en active Application Filing
- 2003-10-07 MX MXPA05003664A patent/MXPA05003664A/es active IP Right Grant
- 2003-10-07 AU AU2003282758A patent/AU2003282758A1/en not_active Abandoned
- 2003-10-07 AT AT03774642T patent/ATE429216T1/de not_active IP Right Cessation
-
2005
- 2005-04-04 IL IL167849A patent/IL167849A/en active IP Right Grant
- 2005-04-04 NO NO20051663A patent/NO20051663L/no unknown
- 2005-04-05 ZA ZA200502744A patent/ZA200502744B/en unknown
-
2006
- 2006-03-31 HK HK06104018.4A patent/HK1081880A1/xx not_active IP Right Cessation
-
2009
- 2009-11-20 AU AU2009238370A patent/AU2009238370B2/en not_active Ceased
-
2010
- 2010-12-03 JP JP2010270724A patent/JP2011057700A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NZ539328A (en) | 2007-01-26 |
AU2009238370B2 (en) | 2011-07-21 |
JP2006504739A (ja) | 2006-02-09 |
ATE429216T1 (de) | 2009-05-15 |
HK1081880A1 (en) | 2006-05-26 |
MXPA05003664A (es) | 2005-06-08 |
ES2322954T3 (es) | 2009-07-02 |
AU2009238370A1 (en) | 2009-12-17 |
AU2003282758A1 (en) | 2004-05-04 |
WO2004032913A1 (en) | 2004-04-22 |
KR20050050124A (ko) | 2005-05-27 |
RU2005114504A (ru) | 2005-10-27 |
EP1549305B1 (en) | 2009-04-22 |
BR0314540A (pt) | 2005-07-26 |
PL216373B1 (pl) | 2014-03-31 |
JP2011057700A (ja) | 2011-03-24 |
RU2330649C2 (ru) | 2008-08-10 |
JP4724421B2 (ja) | 2011-07-13 |
CN1703213A (zh) | 2005-11-30 |
CA2501347A1 (en) | 2004-04-22 |
CN100431536C (zh) | 2008-11-12 |
IL167849A (en) | 2011-04-28 |
EP1549305A1 (en) | 2005-07-06 |
DE60327335D1 (de) | 2009-06-04 |
NO20051663L (no) | 2005-05-31 |
US20040138312A1 (en) | 2004-07-15 |
ZA200502744B (en) | 2006-02-22 |
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