PL374558A1 - Methods for the purification of levofloxacin - Google Patents
Methods for the purification of levofloxacinInfo
- Publication number
- PL374558A1 PL374558A1 PL02374558A PL37455802A PL374558A1 PL 374558 A1 PL374558 A1 PL 374558A1 PL 02374558 A PL02374558 A PL 02374558A PL 37455802 A PL37455802 A PL 37455802A PL 374558 A1 PL374558 A1 PL 374558A1
- Authority
- PL
- Poland
- Prior art keywords
- levofloxacin
- purification
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33431601P | 2001-11-29 | 2001-11-29 | |
US35493902P | 2002-02-11 | 2002-02-11 | |
US26296502A | 2002-10-03 | 2002-10-03 | |
US10/263,192 US7629458B2 (en) | 2001-10-03 | 2002-10-03 | Preparation of levofloxacin and hemihydrate thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL374558A1 true PL374558A1 (en) | 2005-10-31 |
Family
ID=31892240
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL02374558A PL374558A1 (en) | 2001-11-29 | 2002-11-27 | Methods for the purification of levofloxacin |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1460997A4 (xx) |
JP (3) | JP2005527484A (xx) |
CN (1) | CN1596256A (xx) |
AU (1) | AU2002365416A1 (xx) |
CA (1) | CA2466860A1 (xx) |
HR (1) | HRP20040546A2 (xx) |
HU (1) | HUP0500285A3 (xx) |
IL (1) | IL162172A0 (xx) |
IS (1) | IS7288A (xx) |
MX (1) | MXPA04005196A (xx) |
NO (1) | NO20042731L (xx) |
PL (1) | PL374558A1 (xx) |
WO (1) | WO2003045329A2 (xx) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2272781T5 (es) | 2001-10-03 | 2010-04-06 | Teva Pharmaceutical Industries Ltd. | Preparacion de levofloxacino hemihidratado. |
CN1735620A (zh) * | 2002-12-16 | 2006-02-15 | 兰贝克赛实验室有限公司 | 纯的左氧氟沙星半水合物和它的制备方法 |
KR100704641B1 (ko) * | 2004-07-21 | 2007-04-06 | 주식회사유한양행 | 고순도의 레보플록사신 제조방법 |
JP2006273718A (ja) * | 2005-03-28 | 2006-10-12 | Shiono Chemical Co Ltd | レボフロキサシン・1/2水和物の製法 |
CN1321121C (zh) * | 2005-04-21 | 2007-06-13 | 浙江医药股份有限公司新昌制药厂 | 左氧氟沙星制备及后处理方法 |
US7964723B2 (en) * | 2008-08-02 | 2011-06-21 | Apeloa-Kangyu | And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate |
CN102070650B (zh) * | 2011-01-28 | 2012-06-27 | 山东省药品检验所 | 左氧氟沙星-n-氧化物的制备方法 |
US20120251685A1 (en) * | 2011-04-04 | 2012-10-04 | Martek Biosciences Corporation | Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same |
CN105823851A (zh) * | 2015-12-15 | 2016-08-03 | 浙江海洋学院 | 一种检测海水中氧氟沙星对映体的方法 |
CN108218892A (zh) * | 2018-03-16 | 2018-06-29 | 乐山职业技术学院 | 一种左氧氟沙星的纯化方法 |
CN114507242B (zh) * | 2022-01-26 | 2023-05-19 | 上虞京新药业有限公司 | 高光学纯度左氧氟沙星的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO166131C (no) * | 1985-06-20 | 1991-06-05 | Daiichi Seiyaku Co | Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser. |
US5237060A (en) * | 1985-12-10 | 1993-08-17 | Bayer Aktiengesellschaft | Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids |
TW208013B (xx) * | 1990-03-01 | 1993-06-21 | Daiichi Co Ltd | |
AU674542B2 (en) * | 1992-10-07 | 1997-01-02 | Derivados Del Etilo, S.A. | Process for obtaining benzoxazines useful for the synthesis of ofloxacin, levofloxacin and derivatives thereof |
KR0125115B1 (ko) * | 1994-03-22 | 1997-12-05 | 김은영 | (-)피페라진 벤즈옥사진 유도체의 제조방법 |
KR100309871B1 (ko) * | 1999-02-24 | 2001-10-29 | 윤종용 | (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법 |
ES2272781T5 (es) * | 2001-10-03 | 2010-04-06 | Teva Pharmaceutical Industries Ltd. | Preparacion de levofloxacino hemihidratado. |
-
2002
- 2002-11-27 AU AU2002365416A patent/AU2002365416A1/en not_active Abandoned
- 2002-11-27 JP JP2003546834A patent/JP2005527484A/ja active Pending
- 2002-11-27 EP EP02791339A patent/EP1460997A4/en not_active Withdrawn
- 2002-11-27 PL PL02374558A patent/PL374558A1/xx not_active Application Discontinuation
- 2002-11-27 CN CNA028236440A patent/CN1596256A/zh active Pending
- 2002-11-27 HU HU0500285A patent/HUP0500285A3/hu unknown
- 2002-11-27 MX MXPA04005196A patent/MXPA04005196A/es not_active Application Discontinuation
- 2002-11-27 CA CA002466860A patent/CA2466860A1/en not_active Abandoned
- 2002-11-27 IL IL16217202A patent/IL162172A0/xx unknown
- 2002-11-27 WO PCT/US2002/038182 patent/WO2003045329A2/en active Application Filing
-
2004
- 2004-05-27 IS IS7288A patent/IS7288A/is unknown
- 2004-06-15 HR HR20040546A patent/HRP20040546A2/hr not_active Application Discontinuation
- 2004-06-29 NO NO20042731A patent/NO20042731L/no not_active Application Discontinuation
-
2006
- 2006-05-01 JP JP2006127862A patent/JP2006219496A/ja not_active Withdrawn
-
2007
- 2007-08-22 JP JP2007216178A patent/JP2008007517A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN1596256A (zh) | 2005-03-16 |
JP2006219496A (ja) | 2006-08-24 |
IS7288A (is) | 2004-06-21 |
EP1460997A4 (en) | 2005-06-15 |
AU2002365416A1 (en) | 2003-06-10 |
JP2005527484A (ja) | 2005-09-15 |
HUP0500285A3 (en) | 2009-03-30 |
WO2003045329A2 (en) | 2003-06-05 |
CA2466860A1 (en) | 2003-06-05 |
JP2008007517A (ja) | 2008-01-17 |
EP1460997A2 (en) | 2004-09-29 |
MXPA04005196A (es) | 2005-11-23 |
NO20042731L (no) | 2004-06-29 |
HUP0500285A2 (hu) | 2005-06-28 |
WO2003045329A3 (en) | 2004-02-19 |
IL162172A0 (en) | 2005-11-20 |
HRP20040546A2 (en) | 2004-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |